1.metabolites.counter Description: the extracted human metabolites from five fields of MEDLINE records. 11,986 Format: metabolite|frequency (document count) 2.CoMN.counter Description: the weighted co-occurrence metabolite network (CoMN), 6,996 nodes and 986,186 edge Format: metabolite1|metabolite2| co-occurrence 3.CoMN_normalized.counter Description: the weighted co-occurrence metabolite network (CoMN) and normalized, 6,996 nodes and 986,186 edge Format: metabolite1|metabolite2| normalized weight 4. ranked_medline_all_butyric_p-cresol_sulfate_TMAO.counter Description:11,706 metabolites ranked using the combined seeds of butyric acid, p-cresol sulfate and trimethylamine n-oxide (TMAO), weighted co-occurrence metabolite network (CoMN) was used. Format: metabolite|score 5. ranked_medline_all_butyric_p-cresol_sulfate_TMAO_top100.curated Description: Manually curated top 100 metabolites ranked based on weighted CoMN constructed from metabolites extacted from five fields of MEDLINE records, using comined seeds (butyric acid, p-cresol, and TMAO). Format: metabolite|evidence. 6. combined_curatedTop100_HMDB.txt Description: the list of 220 microbial metabolites (172 from HMDB and additional 48 from manual curation of top 100 metabolites). 7. count_pathway.output Description: a total of 1,316 genetic pathways that are significanlty associated with at least one microbial metabolite and ranked by the number of signficantly associated microbial metabolites Format: pathway|the list of significantly associated microbial metabolites| number of significantly associated microbial metabolites 8. count_pathway.output ranked_medline_all_butyric_p-cresol_sulfate_TMAO_top100.curated