@relation 'Reuters-21578 Corn ModApte Test-weka.filters.unsupervised.attribute.NumericToBinary-weka.filters.unsupervised.instance.RemoveFolds-S0-N5-F1' @attribute Text string @attribute class-att {0,1} @data 'After 4 well tolerated cycles of bortezomib and dexamethasone, blood tests showed a complete hematological response with full reversal of cholestasis.',1 'AIM : To describe the clinical, endoscopic and histopathological features of patients with ulcerative esophagitis associated with alendronate sodium.',1 'The relative risk of death for oral naltrexone subjects was 7.4 times (high-risk period, p < 0.0001) or 2.8 times (low-risk period, p = 0.055) that of methadone subjects.',1 'Prolonged bradyasystole and seizures following intravenous adenosine for supraventricular tachycardia.',1 'Dipyridamole administration provokes an activation of sympathetic tone which can be detected even in the absence of myocardial ischemia and is not related to blood pressure changes.',1 'We investigated the effects of the nonsteroidal antiinflammatory agent, ibuprofen, in a rat model of chronic Pseudomonas endobronchial infection and inflammation.',1 'The number of reports of blurred vision and tearing was significantly higher in the timolol GS group than in the timolol solution group (P = 0.04), whereas burning/stinging was reported more frequently in the timolol solution group than in the timolol GS group (P = 0.04).',1 'Atorvastatin-induced hemorrhagic cystitis: a case report.',1 'Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia.',1 'Compared with cyclosporine treatment, tacrolimus has been shown to be associated with decreased acute and chronic rejection, improved renal function over the long-term post-transplant, and a lower incidence of hyperlipidaemia and hypertension.',1 'Nasal midazolam is efficient in the treatment of acute seizures.',1 'RESULTS : Of the tested mediators (prostaglandin [PG]D2, leukotriene (LT)B4, platelet-activating factor (PAF), histamine, LTC4, and eosinophil chemotactic factor of anaphylaxis [ECF-A]), LTB4 and PAF induced ECP release from eosinophils.',1 'The purpose of this study was to describe the dose-response relationship of epidural morphine for postcesarean analgesia for quality of analgesia and relation to the side effects of pruritus, nausea, and vomiting.',1 'The most common toxicities were Grade 3 or 4 myelosuppression after cyclophosphamide/cytarabine and allergic reactions to asparaginase.',1 'Diarrhea occurred in 24% of patients in the flutamide plus LHRH-A group compared with 10% of patients in the bicalutamide plus LHRH-A group (P < 0.001).',1 'RESULTS : Nicotine-facilitated norepinephrine release was significantly and maximally inhibited by isoflurane at concentrations that enhance pain sensitivity in vivo (0.38%).',1 'Children were tested for gait ataxia, amnesia, and diplopia during a screening session and again after triazolam.',1 'CONCLUSION : From a societal perspective, treatment with cholinesterase inhibitors or memantine was more effective but also more costly than standard care for mild to moderate vascular dementia.',1 'SR 141716A (2 mg/kg, i.p.) administered 40 min before apomorphine (40 and 80 microg/kg, s.c.) increased the number of penile erection and yawning responses.',1 'Letter: Hypotension with intravenous salbutamol in premature labour.',1 'High-dose peripheral inositol also reverses the limbic seizures induced by Li-pilocarpine, and using gas chromatography was shown to increase brain inositol levels that had been reduced by Li treatment.',1 '[The use of cortisone preparations in acute and chronic pancreatitis].',1 'Combined fluticasone propionate and salmeterol reduces RSV infection more effectively than either of them alone in allergen-sensitized mice.',1 'Endothelin modulates L-NG-nitroarginine-induced enhancement of vasoconstriction evoked by norepinephrine.',1 'Furthermore, these findings may indicate the dysregulation of 3beta-hydroxysteroid dehydrogenase (3beta-HSD) activity, the enzyme involved in the biosynthesis of cortisol and DHEA through the pregnenolone-progesterone pathway, and that it may offer an opportunity for drug discovery targeting re-regulation of 3beta-HSD activity for potential therapeutic application in HIV-1C infection.',1 'Relationship between testosterone, sex hormone binding globulin and plasma amyloid beta peptide 40 in older men with subjective memory loss or dementia.',1 'Preventive effects of Hange-shashin-to on irinotecan hydrochloride-caused diarrhea and its relevance to the colonic prostaglandin E2 and water absorption in the rat.',1 'Twelve weeks after streptozotocin-induced diabetes, these transgenic mice showed a more severe proteinuria, mesangial expansion, and a decrease in matrix metalloproteinase-2 activity compared to diabetic wild-type mice.',1 'Vertebral osteomyelitis and epidural abscess in a patient receiving enfuvirtide.',1 'The primary toxicity was leukopenia with the carboplatin regimens and nausea and vomiting with the cisplatin regimen.',1 'We describe here a case of severe acute pancreatitis related to tigecycline in order to highlight the possible occurrence of this adverse event and to remind clinicians to measure the lipase rate if in any doubt.',1 'Coma induced by abuse of gamma-hydroxybutyrate (GBH or liquid ecstasy): a case report.',1 'Influence of cyclophosphamide treatment and neonatal thymectomy on glomerular changes in rats with long-term alloxan diabetes.',1 'The pain was rapidly relieved by the administration of intravenous aminophylline.',1 'Early onset of nephrotic syndrome after treatment with D-penicillamine in a patient with Wilsons disease.',1 'Endotoxin-induced fever in dogs resulted in a decrease of approximately 25% in levels of gentamicin in serum 30 and 60 min after intravenous injection of the antibiotic (1.5 mg/kg) when compared with corresponding afebrile values.',1 'Selective inhibition of COX-2 by rofecoxib reduces portal hypertension and this is associated with antifibrotic activity as well as a reduction of COX-2-derived vasoactive substance.',1 'With the release of duloxetine, the first FDA-approved medication for stress urinary incontinence, pharmacologic therapy (which has not had a significant role in stress urinary incontinence) will gain more attention.',1 'In the first case, the mother took 800 mcg of misoprostol orally at the time of expected menses and experienced slight vaginal bleeding and intense abdominal pain.',1 'We compared the degree of sedation and frequency and intensity of adverse behaviors in dogs associated with nalbuphine when combined with acepromazine or xylazine compared with those of acepromazine or xylazine alone.',1 'We have therefore studied the elimination of the nonionic x-ray contrast medium iopromide (Ultravist) during dialysis in nine anuric patients with end-stage renal failure.',1 'Diabetes was induced by streptozotocin and chemical carcinogenesis was induced by the carcinogen 4-nitroquinoline N-oxide.',1 'Although the efficacy of sildenafil was negatively affected by factors as poor control and longer duration of diabetes and presence of more than one diabetes-related complication, however, the global efficacy and the overall patients satisfaction were high.',1 'The efficacy of labetalol, an alpha and beta receptor antagonist, was evaluated in 12 normotensive patients with stable angina pectoris in a single blind dose ranging study.',1 'Thymus involution and inhibition of spleen growth accompanies streptozotocin-induced diabetes in rats; possible relationship of these changes to the elevated hydrolase levels in diabetic plasma.',1 'OBJECTIVE : To investigate the clinical efficacy and safety of intravenous diltiazem compared with nitroglycerin in the patients with unstable angina pectoris.',1 'Since, unlike many other cell types, proliferating early (CD34+) hematopoietic precursors do not induce alkyltransferase, myelosuppression may be the dose-limiting toxicity of the combination of O6-benzylguanine plus BCNU in clinical trials.',1 'Eighty percent (70/87) of Parkinsons disease patients and 90% (10/11) of DLB patients had partial to complete resolution of psychosis using quetiapine (p = .40).',1 'Evaluation of hypersensitivity to microencapsulated ampicillin in guinea pigs.',1 'Pretreatment with methylprednisolone did not increase the time to arrhythmia or death and did not decrease the number of cats dying after acute coronary occlusion.',1 'CONCLUSIONS : In persons who stopped smoking with 7 weeks of bupropion treatment, sustained-release bupropion for 12 months delayed smoking relapse and resulted in less weight gain.',1 'OBJECTIVES : To evaluate the long-term safety, tolerability, effectiveness, impact on quality of life, and medication satisfaction of sumatriptan/naproxen sodium in the acute treatment of migraine headache in adolescents.',1 'Because of its relatively few and less serious side-effects tamoxifen is the agent of first choice for soft tissue and lung metastases.',1 'omega-Conotoxin GVIA and prazosin, but not felodipine, cause postural hypotension in rabbits.',1 'We report here that hypoxia inhibits mRNA translation by suppressing multiple key regulators, including eIF2alpha, eEF2, and the mammalian target of rapamycin (mTOR) effectors 4EBP1, p70S6K, and rpS6, independent of HIF.',1 'The anti-ischemic effect of IS-5-MN, diltiazem and metoprolol was evaluated by assessing the time to onset of ischemia (400.8 +/- 41.1 vs 394.1 +/- 36.0 vs 412.7 +/- 36.6 secs respectively, all p > or = 0.05), duration of ischemia (390.9 +/- 58.5 vs 447.6 +/- 65.9 vs 419.4 +/- 58.7 secs respectively, all p > or = 0.05), duration of exercise 464.0 +/- 32.9 vs 476.8 +/- 32.5 vs 502.6 +/- 31.3 secs respectively, all p > or = 0.05) and severity of ischemia by scoring system (10.0 +/- 1.5 vs 10.7 +/- 1.4 vs 9.8 +/- 1.5 respectively, all p > or = 0.05).',1 'OBJECTIVE : To investigate the effects of Egb761, an extract of ginkgo biloba , and dipyridamole on inducible NO synthase (iNOS) in rabbits after myocardial ischemia-reperfusion injury.',1 'However, amiodarone reduced the incidence of atrial fibrillation in elderly patients (age > or = 60 years): it occurred in 20 of 75 (26.7%) patients on amiodarone and in 28 of 65 (43.1%) patients in the placebo group (P = .05).',1 'Another case that presented with a severe picture of intracranial hypertension and visual impairment was treated with Escin and dexamethasone without positive results.',1 'We therefore leave this an open question, only laying down that, as indicated by the hyalin albuminous matrix left when calcium salts are dissolved out of an area of calcification, there must exist a calcium soap- or fat-albuminate similar to the potassium and sodium soap-albuminates already mentioned-such an albuminate as we can form with calcium soaps in the test tube.',1 '[Prevention of hemorrhagic cystitis due to cyclophosphamide for conditioning of bone marrow transplantation].',1 'In the first study, patients with moderate or severe atopic dermatitis on the trunk and extremities were randomised to 3 weeks of treatment with topical 0.1% tacrolimus or the mid-potency topical corticosteroid 0.12% betamethasone valerate.',1 'About one year after the combined administration to rats of alloxan or streptozotocin with poly(ADP-ribose) synthetase inhibitors, diabetes did not develop but islet B-cell tumors were found frequently.',1 'Therefore, the aim of this study was to compare the temporal activation of NF-κB in rat and human insulin producing cells and relate this to the dynamics of cell death, STAT-1 activation and the production of nitric oxide (NO).',1 'Biopsies from donors with steroid treatment, drug abuse and combined nicotine and alcohol abuse could not be established beyond passage 0 degrees or 1 degree, respectively.',1 'Ketoprofen, peginterferon 2a and ribavirin for genotype 1 chronic hepatitis C: a phase II study.',1 'Thus, while we agree that physicians must be aware of the potential for antimicrobial hepatotoxicity, we believe that this case study is not a solidly documented case of hepatitis attributable to gatifloxacin and overlooks other possible causes of acute hepatitis of which prescribers should be aware.',1 'Platelet prostaglandin generation (malondialdehyde production) and platelet sensitivity to prostacyclin (a vasodilator and platelet aggregation inhibitor) and to epoxymethanodienoic acid (EMA) (a vasoconstrictor and platelet aggregation stimulant endoperoxide analog) were studied in patients with angina pectoris and in control subjects.',1 'This first evaluation must be completed by a karyotype analysis in case of primary amenorrhea or by the measurements of free testosterone, androstanediol glucuronide and testosterone glucuronide in case of hirsutism, and may be followed by X-rays, echography or dynamic tests depending on the first results.',1 'After establishing conditions that achieved significant gene delivery, the authors introduced the Herpes Simplex Virus Thymidine kinase (HSV-tk) gene into the cells using the cationic liposome reagent, Metafectene, followed by the administration of ganciclovir.',1 'Azoospermia or severe oligospermia was found in 13 of 17 patients receiving cyclophosphamide with or without colchicine, whereas the sperm count was almost normal in six patients treated with colchicine alone and in four patients receiving neither drug (control patients).',1 'After releasing the tourniquet, propofol 2 mg kg(-1) was injected in 30 s. Pain was evaluated on a numerical scale (0-10) where 0 represented no pain and 10 the most severe pain possible.',1 'It is known that prostate specific antigen (PSA) is strongly androgen dependent, but little is known about the effects of gonadotropin and testosterone treatments on the prostate and serum PSA levels in male hypogonadism.',1 'Co-supplementation of single and multi doses of vitamins C and E ameliorates cisplatin-induced acute renal failure in mice.',1 'Three cases of myocardial infarction (MI) in women taking bromocriptine for milk suppression are presented.',1 'Both are free of episodes of choreoathetosis under the administration or very low dosis of carbamazepine.',1 'Subjects receiving theophylline had more emesis (p < 0.05), and control patients had more tremor (p < 0.05).',1 'The 9-year-old female Boxer was being treated with an IV constant rate infusion of lidocaine hydrochloride because of ventricular arrhythmias during the initial examination; physical examination re-vealed weakness, pale mucous membranes, prolonged capillary refill time, weak femoral pulses, and tachycardia (heart rate, 265 beats/min).',1 'METHODS : Thirty-nine pretreated patients with advanced solid tumors received escalated doses of PEG-LD (10-16 mg/m(2)), paclitaxel (100-120 mg/m(2)) and L-OHP (50-70 mg/m(2)) every 2 weeks.',1 'All had dermatological manifestations, eosinophilia and systemic (haematological and hepatic) manifestations that could be attributed to treatment with aromatic AEDs (carbamazepine, 2 patients; lamotrigine, 3 patients; phenytoin, 3 patients).',1 'METHODS : The Cochrane Library, MEDLINE, EMBASE and PsycINFO were searched (from 1980 to June 22, 2010) using terms for included drugs (aripiprazole, clozapine, olanzapine, quetiapine, risperidone, ziprasidone, SGAs) and indications (elderly, dementia, Alzheimers disease).',1 'CONCLUSION : The injection of prilocaine plus meperidine into the nasal pack 15 minutes before nasal packing removal provides effective analgesia and mild sedation during the procedure.',1 'The cytological hallmarks of het-R het-V incompatibility (increased septation, vacuolization, coalescence of lipid droplets, induction of autophagy, and cell death) are also observed during rapamycin treatment.',1 'To rule out a possible decrease in cisplatin antitumor activity by a direct effect of short-term glucocorticosteroid treatment, survival was studied in mice inoculated with P388 leukemia and then treated with cisplatin preceded by a single high dose (1.5 mg/kg) of dexamethasone (Dex).',1 'We describe eosinophilic meningitis associated with ibuprofen therapy in a young woman who had no evidence of underlying illness.',1 'Stewarts physicochemical approach in neurosurgical patients with hyperchloremic metabolic acidosis during propofol anesthesia.',1 'One hundred twenty patients undergoing major abdominal surgery under general and thoracic epidural anesthesia (T9-11) were assigned to groups receiving patient-controlled epidural analgesia with ropivacaine 0.2% wt/vol (R), ropivacaine 0.2% wt/vol + sufentanil 0.5 microg/mL (R+S0.5), 0.',1 'Capsaicin-induced ear edema was significantly inhibited by preadministration of 5-HT2 receptor antagonists such as ketanserin (2 mg/kg, i.v.) and LY 53857 (1 mg/kg, i.v.), but not 5-HT1-, 5-HT3- and 5-HT4-receptor antagonists.',1 'The case history of a man with refractory chronic lymphocytic leukaemia who developed acute renal failure following treatment with fludarabine is presented.',1 'CONCLUSION : This study suggests that the daytime diurnal IOP is not statistically different between the dorzolamide/timolol fixed combination and latanoprost/timolol fixed combination in primary open-angle glaucoma and ocular hypertensive patients.',1 'Lacosamide for pain.',1 'The most useful oral medications for erythromelalgia seem to be aspirin, propranolol, clonazepam, cyproheptadine, drugs inhibiting serotonin re-uptake (venlafaxine and sertraline), tricyclic antidepressants (amitriptyline, imipramine), anticonvulsants (gabapentin), calcium antagonists (nifedipine, diltiazem), and prostaglandins (micoprostol).',1 '[Thrombophlebitis by megestrol acetate in patients with human immunodeficiency virus infection].',1 'In experiments measuring antigen-induced release of slow reacting substance of anaphylaxis and histamine from minced lung, virus infection did not alter the sensitivity or the maximum effects of ovalbumin.',1 'Efficacy and tolerability of losartan in hypertensive patients with renal impairment. Collaborative Group.',1 'CONCLUSION : CEC is suggested to be a promising predictive marker of the clinical efficacy of the CBDCA plus paclitaxel regimen in patients with NSCLC.',1 'Effects of 6-hydroxydopamine lesions of the nucleus accumbens septi and olfactory tubercle on feeding, locomotor activity, and amphetamine anorexia in the rat.',1 'Findings were: 1) in all 4 groups the parasite rates declined to levels of 3.3-7% on day 3 and to only 1.3-3.4% of the original level by day 5, 2) the percentage of recrudescence among subjects with diarrhea (10.8%) at the time of medication is slightly higher than that among those without diarrhea (7.1%) and in the 14 and over age group recrudescence was less in group 1 (4.1%) than group 4 (9.7%), in which the adult dosage was limited to a standard 450 mg of chloroquine base, 3) of the 32 detected cases that became positive again between day 10-60, malaria parasites were found on only 1 occasion in 21 and twice in 2 of them, 4) the gametocyte rates increased in all groups but the rise in the 14 and over age group was less pronounced, 5) no side effects other than vomiting were reported (rate of between 2.5-8%), 6) a single-dose treatment with chloroquine in dosages of 10 mg of base/kg body weight or higher failed to prevent the reappearance of parasites within 2 months of treatment in 6.5-11% of children in the 1-9 year age group, 7) the 4 types of treatment with chloroquine proved to be equally effective in all age groups, and 8) dosages of chloroquine adjusted to body weight range would appear preferable and could be used by health professionals in mass drug administration studies.',1 'To evaluate the potential contribution of aldosterone towards the cardiac complications of diabetes, this study examined the effects of chronic aldosterone receptor blockade (with spironolactone) on isolated working heart function in streptozotocin (STZ) - induced diabetic rats.',1 'We have measured testosterone and dihydrotestosterone in procured recurrent prostate cancer specimens using liquid chromatography tandem mass spectrometry.',1 'Lidocaine is particularly useful when ventricular fibrillation or ventricular tachycardia tends to recur.',1 'The most common adverse effects related to doripenem therapy were headache, nausea, diarrhea, rash, and phlebitis.',1 'Morphological effects of sympathetic nerve stimulation on rat parotid glands 3-4 weeks after the induction of streptozotocin diabetes.',1 'In contrast, captopril given from 1 to 21 days after infarction did not lead to improved cardiac function; instead, tachycardia together with a decreased stroke volume suggested deterioration, rather than improvement, of cardiac function.',1 'CONCLUSIONS : The antagonist profile from the current study is most consistent with the theory that the alpha2B-adrenergic receptor subtype mediates the analgesic effect of intrathecally administered tizanidine on CCI-associated neuropathic pain.',1 'BACKGROUND: The American Academy of Ophthalmology recommendations for screening of chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy were published in 2002, but improved screening tools and new knowledge about the prevalence of toxicity have appeared in the ensuing years.',1 '[Acute renal failure caused by sulfadiazine crystalluria in AIDS. An historical resurgent iatrogenic complication].',1 'The third-generation AIs, anastrozole and letrozole, have been shown to be as effective or more effective than megestrol acetate and tamoxifen as second- and first-line therapies for the treatment of postmenopausal patients with metastatic breast cancer, and exemestane has been approved for second-line use.',1 'In thrombocytopenia, heparin therapy must be discontinued before hemorrhagic or thromboembolic complications occur.',1 'Trandolapril led to a significant decrease in serum EPO in patients with chronic renal failure.',1 'Granulomatous hepatitis due to combination of amoxicillin and clavulanic acid.',1 'The major effect of milrinone at the 2 highest doses was the induction of ventricular fibrillation and death in approximately 25% of the rats (SHAM 2/9, CHF 1/10 and CLIP 7/22).',1 'In the subsample, the epinephrine and norepinephrine levels were higher in those reporting more frequent episodes of back pain, the largest differences occurring at the end of work.',1 'Comparison of epidural fentanyl with sufentanil. Analgesia and side effects after a single bolus dose during elective caesarean section.',1 'The beneficial effect of n-3 polyunsaturated fatty acids on doxorubicin-induced chronic heart failure in rats.',1 'Efficacy and tolerability of candesartan cilexetil vs. amlodipine as assessed by home blood pressure in hypertensive patients.',1 'Management of a pediatric patient on the Berlin Heart Excor ventricular assist device with argatroban after heparin-induced thrombocytopenia.',1 'It is proposed that alterations in fatty acid composition in vivo and evidence of lipid peroxidation occur as a result of cell death rather than an initiating event in halothane induced hepatic necrosis in rats.',1 'Pharmacological modulation of leukotriene D(4) attenuates the development of opioid dependence in a mouse model of naloxone-induced opioid withdrawal syndrome.',1 'We investigated the activity of a weekly continuous paclitaxel regimen in patients with recurrent platinum-resistant ovarian cancer.',1 'The effect of tumor cell density on the cellular pharmacokinetics of doxorubicin (DXR) and cisplatin (CDDP) was studied using MOLT-3 human acute lymphoblastic leukemia cells.',1 'PURPOSE : To clarify and compare the antitumor effects and specific biodistribution of NK012, an SN-38-incorporating polymeric micelle, in mice bearing multiple liver metastases of human colon cancer HT-29 cells with irinotecan hydrochloride (CPT-11).',1 'The identification and characterization of the pathways that mediate imatinib-induced cell death in GIST provide for a better understanding of targeted therapy and may facilitate the development of new therapeutic approaches to further exploit these pathways.',1 'The cases were a 64-year-old man with brain metastases from a small cell carcinoma of the lung, a 64-year-old woman with bone metastases from carcinoma of the breast on tamoxifen and a 59-year-old man with a squamous cell carcinoma (NSCLC) of the bronchus and positive mediastinal lymph nodes.',1 'Patients with asthma and bronchitis showed the greatest response to salbutamol and their results were used to analyze the usefulness of the reversibility indices.',1 'Mazzotti-type reactions, such as itching, rash, peripheral sensory phenomena and swellings, were more severe or frequent with amocarzine than ivermectin.',1 'In patients with N2 stage IIIA NSCLC, paclitaxel/carboplatin is an active and very well-tolerated induction regimen.',1 'One patient in the danazol group discontinued treatment due to a cutaneous rash as a probable adverse reaction at the beginning of the study.',1 'Instead, the reproducibility of the hematuria from the upper urinary system strongly suggests an unexpected gefitinib-related adverse effect.',1 'Our study suggests that the addition of verapamil to ACE inhibitors can reverse ACE-induced increase in creatinine levels in elderly hypertensive patients in whom this side effect is observed.',1 'Because of recent recommendations that lidocaine be used prophylactically in all coronary care unit (CCU) patients with suspected myocardial infarction (MI), an approach not used in our CCU, we analysed our experience with ventricular fibrillation (VF) occurring in the setting of an acute MI.',1 'Dose-dense cisplatin/paclitaxel. a well-tolerated and highly effective chemotherapeutic regimen in patients with advanced ovarian cancer.',1 'The dog was considered to have systemic aspergillosis and was treated with itraconazole for 7 months, until it was euthanatized because of persistent vomiting and anorexia.',1 'The developed propofol method was applied to a forensic autopsy case where a suspected propofol misinjection occurred eight days prior to death, and the tissue analysis was vital to the case.',1 'The first patient was a 57-year-old man with plaque-type psoriasis on intermittent methotrexate therapy.',1 'BACKGROUND : Because the combination of loperamide and some antimicrobials has proven to be more efficacious than the antimicrobial agent alone in the treatment of travelers diarrhea, we set out to prove loperamide plus azithromycin was more efficacious than azithromycin alone.',1 'However, among Caucasians, but not African-Americans, prostate cancer risk was positively associated with the ratio of total testosterone to total estradiol (odds ratio relating the fourth to the first quartile: 3.01; 95% confidence interval: 1.42-6.39).',1 'BACKGROUND : We compared the outcome of lifelong treatment with the ACE inhibitor ramipril in young prehypertensive stroke-prone spontaneously hypertensive rats (SHR-SP) and age-matched normotensive Wistar-Kyoto (WKY) rats.',1 'Acute carbamazepine poisoning and hyponatremia.',1 'This report demonstrates the acquisition of nonlinear heart rate dynamics and possible chaos in developing human infants and its loss in brain death and with the administration of atropine.',1 'Recently, several series have reported skin cancer, particularly cutaneous squamous cell carcinoma (C-SCC), following photosensitivity reactions among patients receiving long-term voriconazole (>12 months).',1 'Levetiracetam was safe and well tolerated; the most common levetiracetam-related adverse events were dizziness (6.8%), convulsion (5.7%), and somnolence (5.0%).',1 'A patient being treated for leukemia received lithium carbonate and ticarcillin for sepsis, and polyuria and severe hypernatremia developed.',1 'One female patient (aged 70 years old) developed a marked QTc prolongation (QTc = 0.62 s) within 24 hours of ciprofloxacin administration, with documented torsades de pointes and recurrent syncope that required defibrillation.',1 'The side-effect profile was different than that for tamoxifen, with fewer hot flushes, gynecologic symptoms, endometrial cancers, strokes and thromboembolic events; however, an increased incidence of fractures, joint symptoms and carpal tunnel syndrome was observed.',1 'Although there was a wide individual variation in the dose required, remifentanil seems effective for labor analgesia.',1 'The influence of an increased Ca concentration on reactive hyperemia, work induced vasodilation and pharmacologically induced dilation (adenosine, nifedipine, verapamil) was studied in the blood perfused gastrocnemius of dogs.',1 'We conclude that labetalol is a drug of choice to treat hypertension in acute myocardial infarction because it is very effective; its haemodynamic effects are likely to reduce myocardial oxygen requirements and suggest that labetalol administration does not worsen moderate left sided heart failure.',1 'METHOD : After a 2-week, single-blind placebo lead-in phase, 81 outpatients with DSM-III-R-defined nonpsychotic unipolar major depression and ischemic heart disease were randomly assigned to double-blind treatment with paroxetine or nortriptyline for 6 weeks.',1 'Further studies are required before this device can be recommended as a treatment for endometriosis-associated pelvic pain, hyperplasia, or endometrial adenocarcinoma, or as adjuvant therapy with tamoxifen.',1 'Amiodarone, an iodine-containing drug used frequently in the treatment of cardiac arrhythmias and angina pectoris, has many effects on thyroid hormone metabolism, including decreasing the production of triiodothyronine (T3) and decreasing the clearance of thyroxine and reverse T3.',1 'We characterized the der(11) and der(9) genomic breakpoint junctions in a case of AML following etoposide and doxorubicin.',1 'The Streptozotocin (STZ) model of diabetes is commonly used for studies of diabetic nephropathy although the histological lesions of the kidney are mild and do not resemble those seen in diabetic patients.',1 'Topical imiquimod treatment prevents UV-light induced loss of contact hypersensitivity and immune tolerance.',1 'CONCLUSIONS : The results suggest that VX-710 with paclitaxel has modest activity in paclitaxel-resistant ovarian cancer.',1 'Pravastatin treatment attenuates interstitial inflammation and fibrosis in a rat model of chronic cyclosporine-induced nephropathy.',1 'During therapy, patients receiving oxaliplatin experienced significantly more hand/foot toxicity (eg, "quite a bit" of cold-induced hand/foot pain 26% FLOX v 2.6% FULV) and overall weakness (eg, moderate weakness in 27.4% FLOX v 16.2% FULV).',1 'Less than 1% of participants with asthma or wheeze in our nested study reported avoidance of aspirin because of asthma symptoms.',1 'METHODS : Male Wistar rats received a high fat diet during 2 months followed by a low dose of streptozotocin to induce diabetes (D).',1 'The results suggest usefulness of concurrent therapy of granisetron with methylpredonisolone sodium for cisplatin-induced nausea, vomiting and anorexia.',1 'Acute poisoning with isoniazid causes generalized convulsions which should be treated with intravenous pyridoxine and a rapidly-acting anticonvulsant.',1 'Use of the Naranjo adverse drug reaction probability scale indicated a probable relationship (score of 7) between the patients worsening psychosis and her varenicline therapy.',1 'The ability of FG 7142 to reduce restraint-stress induced gastric ulcer formation was blocked by the benzodiazepine receptor antagonist ZK 93426 and the beta-adrenoceptor antagonist propranolol.',1 'We conclude that nicardipine and phentolamine increase the cumulative dose but do not affect the threshold plasma or brain concentrations required for bupivacaine-induced convulsions.',1 'METHODS AND RESULTS : Forty-six men with stable angina completed a 2-week, single-blind placebo run-in, followed by double-blind randomization to 5 mg testosterone daily by transdermal patch or matching placebo for 12 weeks, in addition to their current medication.',1 'Two patients developed alopecia with carboplatin.',1 'Three episodes of severe hypoglycemia occurred after initiation of insulin glargine therapy.',1 'Bupivacaine infiltration significantly reduced the incidence of wide complex extrasystoles (P less than 0.05) during surgery and the severity of dental pain (P less than 0.05), when assessed at 6 h after operation.',1 'H. pylori infection attenuated the aspirin-induced inhibition of ulcer healing and accompanying fall in the gastric blood flow.',1 'Cancer, thrombosis and heparin-induced thrombocytopenia.',1 'A retrospective review of 25 patients who underwent orthotopic liver transplantation was performed to relate the prevalence and preferred sites of microscopic calcium deposition seen at autopsy to clinical parameters, namely, hypercalcemia, hypercalcemia, hyperphosphatemia, and renal failure.',1 'OBJECTIVE : To report a patient with unrecognized amantadine-induced corneal edema.',1 'METHOD : We examined 21 patients suffering from drug-induced headache during their in-hospital withdrawal from ergotamine (n=8) and compared them with patients during withdrawal from analgesics (n=13) and with healthy controls (n=14).',1 '[Beneficial effect of bromocriptine in a patient with malignant syndrome and hepatic dysfunctions].',1 'Heparin is the usual anticoagulant used, but systemic anticoagulation may persist for hours, and hemorrhage is common.',1 'Occurrence of psychosis in patients with epilepsy randomized to tiagabine or placebo treatment.',1 '[An interesting drug for the treatment of constipation: the association of calcium pantothenate and danthron].',1 'Renal histology revealed more advanced papillary necrosis in rats gavage fed mefenamic acid and caffeine compared with all other groups (p less than 0.0001).',1 'RESULTS : All patients had optic neuropathy between 1 to 6 months (mean = 2.9 months) after starting ethambutol therapy at a dosage ranging from 13 to 20 mg/kg/day (mean = 17 mg/kg/day).',1 'For all patients, aqueous humour was collected during cataract surgery or during an intravitreal injection of triamcinolone acetonide.',1 'This report addresses dose-dependent gabapentin-induced sexual dysfunction reaching total sexual dysfunction (loss of libido, anejaculation, anorgasmia, and impotence) at a total daily dose of only 300 mg.',1 'A longitudinal mixed-model regression for weight change controlling for age, race, sex, body mass index, and percent body fat estimated that zonisamide treatment over the 16-week study duration was associated with significantly greater weight loss than was placebo (t = 6.4; P<.001).',1 'Naproxen in otitis media with effusion.',1 'Synergistic effect of phosphatidylserine with gamma-aminobutyric acid in antagonizing the isoniazid-induced convulsions in mice.',1 'To investigate how corticosteroids affect differentiation of human dendritic cells (DC) in a defined inflammatory environment, we incubated immature DC with dexamethasone in the presence of tumor necrosis factor alpha (TNF-alpha), interleukin-1beta (IL-1beta), and prostaglandin E2.',1 'Uncertainty as to the patholophysiologic processes leading to development of neurologic symptoms, particularly in patients with systemic lupus, and difficulty in following response to clinical trials objectively have been associated with a relative lack of information about the efficacy of cyclophosphamide therapy.',1 'Ventricular tachycardia and/or ventricular fibrillation occurred in 11 of the 16 animals (69%) both before and after methylprednisolone pretreatment.',1 'Valproic acid (VPA) is widely used as an anticonvulsant, but therapy with the drug has been associated with hepatotoxicity, either reversible hepatic dysfunction or irreversible hepatic failure.',1 'Myocardial prostacyclin and thromboxane A2 synthetase activities during ischemia and reperfusion in isolated rabbit heart.',1 'The aim of this paper is to assess the efficacy of albumin and dopamine compared with albumin and dobutamine in treating hypotension in preterm newborn infants (PNI).',1 'Apparatus for measuring limb tonicity in the rat: application to the study of morphine-induced rigidity [proceedings].',1 'Somatostatin analogue (SMS 201-995) but not somatostatin reduces indocyanine green clearance in the portal hypertensive rat.',1 'METHODS : Stable vector control and MOR1 overexpressing human bronchioloalveolar carcinoma cells were evaluated using immunoblot analysis, proliferation and transendothelial extravasation assays with or without Akt inhibitor, mTOR inhibitor (temsirolimus), or the peripheral MOR antagonist, methylnaltrexone.',1 'Yeast-injected rats developed marked fever and exhibited an approximately 7-fold increase in brain levels of prostaglandin E2 and an approximately 2-fold increase in the expression of cyclooxygenase-2 mRNA despite an almost unchanged expression of cyclooxygenase-1 mRNA.',1 'Use of peripheral dopamine antagonist (Motilium) in the treatment of dyspeptic complaints of different origin and in nausea, vomiting.',1 'Severe coagulopathy caused by rifampicin in patients with primary sclerosing cholangitis and refractory pruritus.',1 'Anorexia, nausea, or vomiting developed in 16 patients (59%) but disappeared in all ten patients for whom the digoxin dose alone was reduced, suggesting that digoxin excess caused these symptoms.',1 'We show that CRABPI (encoding cellular retinoic acid binding protein I) is a target of PLZF, which is fused to RARalpha by the t(11;17)(q23;q21) translocation associated with retinoic acid (RA)-resistant acute promyelocytic leukemia (APL).',1 'RESULTS : All patients underwent unilateral tibial bone harvesting using a nontrephination technique under sedation with meperidine and methohexital.',1 'Hypercalcemia and status epilepticus relates to salmon calcitonin administration in breast cancer.',1 'The effects of intravenous clonidine and tizanidine on nociceptive neurons in the nucleus ventralis posterolateralis (VPL) of the thalamus, a key station in the lateral system of ascending pain pathways, were evaluated in urethane-chloralose anesthetized cats.',1 'Plasma testosterone, dominance rank and aggressive behaviour in male rhesus monkeys.',1 'The patients on clobazam maintained greater improvement during the placebo trial period for the variables "somatic anxiety" and "nights of sleep disturbance."',1 'Primary or second renal allograft recipients treated with basiliximab, cyclosporine microemulsion and prednisone immunosuppression were randomized to two study groups in which cyclosporine microemulsion therapy was monitored using a multipointalgorithm or by trough levels.',1 'Oral administration of prednisone to control refractory vertigo in Ménières disease: a pilot study.',1 'Our data also indicate that CYP1A2 poor metabolizers might be more susceptible than extensive metabolizers to dose-related adverse effects of clozapine, such as sedation, myoclonus and seizures.',1 'METHODS : In 12 healthy subjects, anodal excitability-enhancing or cathodal excitability-diminishing tDCS was applied to the motor cortex under a single dose of 20-mg citalopram or placebo medication.',1 'The patient reported benefit from tricyclic antidepressants, guanethidine, and trospium chloride (an anti-cholinergic quaternary amine used in Europe for urinary urgency).',1 'The only other side effect possibly related to ramipril was a dry cough in 1 subject.',1 'PURPOSE : To describe the clinical spectrum of amiodarone-associated optic neuropathy.',1 'Tamoxifen may rarely cause serious TG-related side effects, like acute pancreatitis.',1 'Most are still underway but 3 studies have recently reported their results: the second Cardiac Insufficiency Bisoprolol Study (CIBIS II), the Research in Left Ventricular Dysfunction Study (RESOLVD), and the Metoprolol CR/XL Randomised Intervention Trial in Heart Failure (MERIT-HF) study.',1 'A weakness of CT, however, is its inability to show clearly intraocular lesions that do not contain calcium.',1 'In contrast, for patients who did not receive heparin within the previous 3 months, HIT is an unlikely explanation for thrombocytopenia that occurs within the first 5 days.',1 'This report describes a 31-year-old Korean male patient with schizophrenia who developed dilated cardiomyopathy on treatment with clozapine.',1 'Significance of elevated serum squamous cell carcinoma (SCC)-related antigen and lactate dehydrogenase (LDH) levels in senile erythroderma following eczema.',1 'Other adverse effects of ifosfamide include nephrotoxicity, alopecia, and nausea/vomiting.',1 'An hitherto undefined androgen binding macromolecule(s), with high-capacity binding for natural and synthetic androgens, but not for estrogen and progesterone, seems to be present in these ovarian cancer tissues.',1 '[Acute myocardial infarction as a possible consequence of abrupt withdrawal of verapamil].',1 'D-kyotorphin (D-Kyo) is a synthetic analogue of the neuropeptide kyotorphin and produces naloxone reversible analgesia.',1 'In the follow-up of mild 2HPT after RTx, hypercalcemia and vascular calcification should be monitored carefully by serum parathyroid hormone, calcium and phosphate concentrations, alkaline phosphatase activity, and bone X-ray film.',1 'METHODS : FVB/N wild-type mice (n = 13) were used to evaluate carboplatin-induced myelosuppression in bone marrow by complete blood cell counts after treatment with the CDK4/6 inhibitor PD0332991.',1 'Epidural neostigmine combined with sufentanil provides balanced and selective analgesia in early labor.',1 'The effects of GANU on TLX5 lymphoma and Lewis lung carcinoma are less pronounced than those of BCNU and CCNU, as already reported for L1210 leukemia.',1 'Acute oral treatment with propafenone is simple and effective for the conversion of recent onset AF to SR in patients without clinical signs of heart failure.',1 'OBJECTIVE : To investigate the frequency, mortality rate, and characteristics of stroke in heparin-induced thrombocytopenia and the effect of argatroban therapy in that setting.',1 'However, lidocaine had no effect at some sites where stimulation arrested tremor.',1 'Diabetes mellitus (DM) rats were induced by combination of high-fat diet (HFD) and streptozotocin.',1 'On the basis of clinical observations suggesting interactive effects of biliary obstruction and estrogen therapy on plasma cholesterol levels, a prospective study of the effect of ethinyl estradiol on plasma lipid levels was carried out in a patient with total biliary obstruction.',1 'Administration of multiple doses of ipratropium bromide has been shown to decrease the hospitalization rate in children and adolescents with severe asthma.',1 'Here, we evaluated the efficacy and safety of bevacizumab plus FOLFIRI (irinotecan, 5-fluorouracil, and leucovorin) or FOLFOX (oxaliplatin, 5-fluorouracil, and leucovorin) in metastatic colorectal cancer cases after failure to FOLFIRI and FOLFOX.',1 'From these data the conclusion seems warranted that short-term cyproterone acetate treatment in the given dose not significantly influences pituitary-adrenal function in adult women with idiopathic hirsutism.',1 'Lactulose feeding in piglets: a model for persistent diarrhea and colitis induced by severe sugar malabsorption.',1 'The density of larger microvessels (200 to 500 microm) was selectively decreased in hypercholesterolemia plus thalidomide and accompanied by a decreased fraction of angiogenic, integrin beta(3)-positive microvessels (9.9%+/-0.9% versus 25.5%+/-1.7%; P<0.05 versus hypercholesterolemia), implying decreased angiogenic activity.',1 'Chronic treatment (30 days) with vitamin C or metformin, and donepezil during training trials also improved diabetes-induced memory impairment and reduced oxidative stress and/or choline esterase activity.',1 'CONCLUSIONS : Viral infection appeared to affect theophylline metabolism.',1 'The sensitivity of APL cells to all-trans retinoic acid (ATRA)-induced differentiation has been successfully exploited for treatment of the disease.',1 'We present a case of acute psychosis following sustained release bupropion (SR) overdose.',1 'Low peripheral lymphocyte count before focal radiotherapy plus concomitant temozolomide predicts severe lymphopenia during malignant glioma treatment.',1 'Patients with cyclosporine (n = 42) as first-line immunosuppression displayed more often immunoreactivity to IA-2 and IAA than patients treated with tacrolimus (n = 49) (31% vs. 14%, P = 0.04; 67% vs. 47%, P = 0.04).',1 'The frequency of myopathy in patients with rheumatoid arthritis treated with triamcinolone.',1 'A 72-year-old critically ill and intubated man was transferred to our hospital, because of worsening pneumonia unresponsive to Cefazolin and Meropenem, from the hospital where he had been admitted 8 days before to start maintenance hemodialysis for chronic renal failure but had fever from admission.',1 'Patients treated with zonisamide showed significant weight loss.',1 'Early clinical trials of eptifibatide did not show a significant association between eptifibatide and the development of thrombocytopenia, thrombosis, or disseminated intravascular coagulation.',1 'Exercise-induced acute renal failure (ARF) developed in a 45-year-old man during antihypertensive therapy with losartan and trichlormethiazide.',1 '[Bone and Mens Health. Association between serum testosterone and bone mineral density in patients with diabetes].',1 'A new ulcer model, "unhealed gastric ulcers", induced by chronic treatment with indomethacin in rats with acetic acid ulcers.',1 'We studied the pharmacokinetic and pharmacodynamic aspects of an oral 15-mg dose of midazolam in 6 patients with epilepsy who are also taking carbamazepine (CBZ) or phenytoin (PHT).',1 'The results of these investigations indicate the involvement of spinal adenosine receptors in spinal pathways of central sensitization and in the modulation of somatically induced noxious pain.',1 'We herein report the results of observations on the frequency of cardiomyopathy in doxorubicin-treated sarcoma patients in Germany, Austria, and Switzerland.',1 'Tapering prednisone was used for the first five days of the cycle due to patients history of autoimmune disease (vasculitis and Crohns disease).',1 'Nebulizied solutions of misoprostol and PGE2 effectively blocked the acute bronchospasm caused by a subsequent inhaled antigen challenge in actively sensitized guinea pigs.',1 'Heparin-induced thrombocytopenia (HIT) is a severe immunological adverse effect of heparin treatment.',1 'Compared to ceftriaxone, gatifloxacin was associated with an increased risk of hypoglycemia: (adjusted odds ratio (OR) 2.34, 95% confidence interval (CI) 1.4-4.0).',1 'Phase II studies have shown significant efficacy and a favorable toxicity profile of the combination of pemetrexed plus platinum as first-line therapy for NSCLC.',1 'Prospective study of the neuroprotective activity of sildenafil in a rat spinal ischemia model.',1 'There were also high levels of estradiol and low of gonadotropins in functional ovarian cyst fluid.',1 'The heterotopic calcification in the burn patients is commonly found either in periarticular region or in the muscles, but the occurrence of heterotopic calcification of the burn scar itself in the presence of normal serum calcium, phosphate and alkaline phosphatase is not reported earlier.',1 'Prednisolone, indomethacin, phenylbutazone and aspirin inhibited the carrageenin, formalin-induced edema, cotton pellet granuloma and adjuvant arthritis apparently, but flufenamic acid showed no inhibition on the carrageenin and formalin-induced edema.',1 'CONCLUSION : Our data suggest the involvement of GCS in resistance to imatinib-induced apoptosis, and that targeting GCS by PDMP increased imatinib-induced cell death in drug-sensitive and drug-resistant K562 cells via enhancing ceramide accumulation.',1 'Patients treated a single migraine within 1 hour of onset of migraine head pain and while the pain was mild with either sumatriptan/naproxen or placebo.',1 'CONTEXT : Lorazepam is currently recommended for sustained sedation of mechanically ventilated intensive care unit (ICU) patients, but this and other benzodiazepine drugs may contribute to acute brain dysfunction, ie, delirium and coma, associated with prolonged hospital stays, costs, and increased mortality.',1 '[Treatment of asthma in the adult using a combination of salbutamol 100 micrograms--beclomethasone 50 micrograms. Results of a study on 1917 patients seen in general medicine].',1 'DISCUSSION : Patients and prescribers are reminded of the risk of severe morbidity including seizures associated with tramadol withdrawal.',1 'Glycation of the aorta in rats with streptozotocin-induced diabetes was estimated by determining the early-stage product and the advanced product of the Maillard reaction.',1 'Hypoglycemia induced by the interaction of chlorpropamide and co-trimoxazole.',1 'The incidence of nonhematologic toxicities also was similar, although nausea and vomiting appeared to be less frequent among patients assigned to docetaxel plus carboplatin than among patients receiving comparator regimens.',1 'A positive correlation between baseline breast pain score and serum estradiol level was observed in patients with cyclical mastalgia (r = 0.35, P = .003).',1 'Efficacy of pregabalin and venlafaxine-XR in generalized anxiety disorder: results of a double-blind, placebo-controlled 8-week trial.',1 'The present study aimed at evaluating the efficacy of lacosamide (0.3 to 30 mg/kg), a new anticonvulsant drug, in a model of essential tremor in comparison to the reference compounds propranolol and primidone.',1 'Prompt treatment of acute HZ with acyclovir, valacyclovir or famciclovir is recommend, if patients are over 50 years old or have severe or moderate pain or severe or moderate rash or they are immonocompromised or suffer from herpes zoster ophtalmicus.',1 'Treatment of aged AXC rats with exogenous testosterone did not enhance ventral prostate AMDC activity per 100 micrograms DNA, but it did elevate dorsolateral prostate AMDC activity per 100 micrograms DNA to levels indistinguishable from those characteristic of untreated young AXC rats and caused a 303% increase in ventral prostate ODC activity per 100 micrograms DNA.',1 'Recent case reports indicate that some forms of periodic alternating nystagmus may respond favorably to baclofen therapy.',1 'In the present study, serologic changes in a 69-year-old man were monitored during his treatment with procainamide and after discontinuation of procainamide because of symptoms of drug-induced lupus.',1 'Monitoring methotrexate-induced hepatic fibrosis in patients with psoriasis: are serial liver biopsies justified?',1 'Effect of long-term Helicobacter felis infection in a mouse model of streptozotocin-induced diabetes.',1 'Grades 1 and 2 sensory neuropathy limited thalidomide dose escalation in 3 of 12 patients.',1 'The aging male with reduced testosterone availability may present with a wide variety of symptoms which in addition to frailty and weakness include: fatigue, decreased energy, decreased motivation, cognitive impairment, decreased self-confidence, depression, irritability, osteoporotic pain and the lethargy of anemia.',1 'Psychostimulants such as methylphenidate are used for fatigue in cancer patients.',1 'Superficial edema (42% versus 15%) and fluid retention (45% versus 30%) were more prevalent with imatinib; pleural effusion was more common with dasatinib (17% versus 0%).',1 'Buspirone decreased postprandial aggregate symptom and nausea scores.',1 'Symptomatic hypoglycemia associated with trimethoprim/sulfamethoxazole and repaglinide in a diabetic patient.',1 '96 weeks combination of adefovir dipivoxil plus emtricitabine vs. adefovir dipivoxil monotherapy in the treatment of chronic hepatitis B.',1 'Phase II investigation of docetaxel in pediatric patients with recurrent solid tumors: a report from the Childrens Oncology Group.',1 'Although as many as 121 referred to links between the drug and endometrial abnormalities (polyps or cancers), 55 articles studied the relationship with changes of pap smears, four of which indicated isolated cervical metastasis followed tamoxifen use in patients with breast cancer.',1 'The Kaplan-Meier curve of the incidence of major cardiovascular events in PRoFESS has a striking similarity with the Kaplan-Meier curves of Heart Outcomes Prevention Evaluation (HOPE), EURopean trial On reduction of cardiac events with Perindopril in stable coronary Artery disease (EUROPA) and Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (TRANSCEND) trials for a similar endpoint.',1 'The role of this enzyme has been well demonstrated in the streptozotocin (STZ) induced model of diabetes.',1 'Candesartan prevented development of diabetes mellitus in heart failure.',1 'Finasteride (a drug that blocks testosterone activation) reduced prostate cancer risk by 25%.',1 'The 2-ODS heparin oligosaccharides may be a potential agent for the prevention of C. trachomatis infection.',1 'The serum HMG CoA reductase activity, RBC membrane Na+-K+ ATPase activity, serum digoxin, magnesium, tryptophan catabolites (serotonin, quinolinic acid, strychnine, and nicotine), and tyrosine catabolites (morphine, dopamine, and noradrenaline) were measured in anorexia nervosa, bulimia nervosa, right hemispheric dominant, left hemispheric dominant, and bihemispheric dominant individuals.',1 'Neoadjuvant or pre-radiotherapy chemotherapy administration may reduce chemotherapy-related side effects such as leukoencephalopathy secondary to high-dose intravenous methotrexate, neutropenia and thrombocytopenia following intensive chemotherapy, especially when craniospinal radiotherapy is required.',1 'Systemic administration of the selective KOPr-1 agonist, U69593 (0.16-0.6mg/kg; s.c.), failed to modify cocaine-evoked convulsions or cocaine kindling.',1 'Compared to those without zoster, patients with zoster were significantly more likely to have previously had serious disease manifestations including nephritis, thrombocytopenia or hemolytic anemia, and to have received treatment with cyclophosphamide (all p < or = 0.05).',1 'Sunitinib-induced tumor growth inhibition was associated with increased apoptosis, reduced microvessel density and inhibition of cell proliferation.',1 'Tumour necrosis factor alpha and interleukin 6 barely altered DNA synthesis, whereas hepatocyte growth factor (HGF), keratinocyte growth factor (KGF) and the heparin-binding epidermal growth factor-like growth factor (HB-EGF) were potent inducers of DNA replication in both, GSTp-neg and GSTp-pos cells.',1 'Phenytoin and postoperative epilepsy. A double-blind study.',1 'RESULTS : In this study, we first demonstrated differential change in expression of proton-sensing GPCRs in peripheral inflammation induced by the inflammatory agents capsaicin, carrageenan, and complete Freunds adjuvant (CFA).',1 'Community pharmacists counseling about metformin-associated lactic acidosis.',1 '[Tetracycline ulcer of esophagus].',1 'In aspirin-sensitive asthma, inhibition of aggregation is observed; platelets become refractory to the action of ADP, with the decrease but not increase of cAMP level accompanying it after the action of the aggregation inducer.',1 'An early substitution of testosterone could prevent a full fledged gynecomastia.',1 'Our results suggest that 5 mg/day folic acid as preconception supplementation in women with epilepsy is effective to balance the impact of AEDs on folate metabolism in women with epilepsy.',1 'BACKGROUND AND PURPOSE : Argatroban, a direct thrombin inhibitor, has been shown to reduce neural injury after transient cerebral ischemia.',1 'Pain, analgesic requirements, mouth opening and emesis were assessed in 60 patients who received either piroxicam 40 mg or placebo before dental surgery under general anaesthesia which included breathing either halothane or isoflurane.',1 'Calcinosis universalis is characterized by the deposit of calcium salts in skin, subcutaneous tissue, tendons and muscles.',1 '[Severe sinus node dysfunction during a lithium intoxication (authors transl)].',1 'In this work, we examined the contribution of GABA receptors to the effect of sildenafil, a phosphodiesterase 5 inhibitor, in a neuropathic pain rat, and assessed the hemodynamic effect of sildenafil in normal rats.',1 'To identify risk factors associated with taste loss to terbinafine, we performed a case-control study of 87 reports of probably terbinafine-induced taste loss and 362 controls on terbinafine without taste loss, who had filled prescriptions from the same pharmacy and GP.',1 'Pretreatment with chlorpromazine (20 mg/kg) 30 minutes before inducing ischemia for up to 3 hours virtually completely prevented this ischemic cell death.',1 'Here we show that retinoic acid-inducible gene (RIG)-I-like receptors (RLRs) in cooperation with Toll-like receptor (TLR) 9 is required for expression of type I interferons (IFNs) after infection with herpes simplex virus (HSV).',1 'Diltiazem, and possibly verapamil and nifedipine as well, appears to retard myocardial damage that accompanies ischemia.',1 'Analysis of variance indicated that both doses of adenosine reduced the renin response to renal artery hypotension.',1 'Univariate analysis showed that patients with low serum magnesium level, low serum potassium level, high serum creatine kinase level, changes of electrocardiogram, chest distress and palpitation, nausea and vomiting as well as muscular soreness had more severe paralysis, while multivariate analysis revealed that serum magnesium < 0.8 mmol/L (OR 8.3, 95%CI 1.0 - 68.4, P < 0.05), serum potassium 1.5 - 1.8 mmol/L (OR 1.3, 95% CI 1.1 - 16.0, P < 0.01) and serum creatine kinase > 200 U/L (OR 1.1, 95%CI 1.0 - 1.1, P < 0.01) were the independent factors for the severity of paralysis.',1 'Moreover, we demonstrated that raltitrexed/5-fluorouracil plus folinic acid induced a distinct S-phase block of the cell cycle, as well as a potentiation of the apoptotic cell death, compared with 5-fluorouracil plus folinic acid or raltitrexed/5-fluorouracil combination.',1 'Flecainide: steady state electrophysiologic effects in patients with remote myocardial infarction and inducible sustained ventricular arrhythmia.',1 '[The hypertensive emergency and severe hypertension: experiences with nifedipine].',1 'In addition, a strong correlation was found between actual daily mean dose and time to onset of pleural effusions in patients treated with a daily mean dose >100 mg/day of dasatinib (P = 0.01).',1 '[Acute effects of nifedipine and verapamil on arterial pressure, at rest and during and after exercise in hypertensive patients].',1 'Thus, nifedipine improved endothelial function and EPC function in stage 1 hypertensive subjects.',1 'Riluzole prevented or attenuated ischemia-induced necrosis, apoptosis, and cytoskeletal proteolysis, depending on the dose and the timing of administration.',1 'PURPOSE OF REVIEW : Heparin-induced thrombocytopenia (HIT) is a prothrombotic complication of heparin therapy caused by antibodies against platelet factor 4/heparin complexes.',1 'Judicious use of cyclophosphamide seems to be beneficial for severe ocular inflammation cases where the potentially vision-saving benefits outweigh the substantial potential side effects of therapy, or when indicated for associated systemic inflammatory diseases.',1 '[Percutaneous extracorporal circulation in cardiogenic shock caused by a mixed poisoning with metildigoxin, nifedipine and indapamide].',1 'Minocycline hyperpigmentation: skin, tooth, nail, and bone involvement.',1 'Only 3 cases of imatinib-induced tumor lysis syndrome have been reported.',1 'Enhanced endogenous epinephrine release from the vascular adrenergic neurons in spontaneously hypertensive rats.',1 'To investigate the influence of the renal prostaglandins on these parameters, pigs with complete unilateral ureteral obstruction (UUO) were studied under general anesthesia after administration of indomethacin 30 minutes before obstruction.',1 'In this study we investigated the development of a cisplatin-induced neuropathy and the protective and therapeutic actions of ORG 2766 in mature rats.',1 'The wide use of sildenafil by patients with erectile dysfunction and cardiovascular disease has resulted in a considerable number of independent studies investigating the cardiovascular safety and functional role of the phosphodiesterase type 5-cyclic guanosine monophosphate-nitric oxide pathway in the cardiovascular system.',1 'Lidocaine and particularly ketamine were associated with frequent side-effects, the most common being somnolence and dizziness.',1 'The purpose of this study was to determine the relationship of epithelial cell types in the ventral prostate glands of castrated mice treated with testosterone during the period of maximum DNA synthesis, mitosis, and restitution of the epithelium.',1 'Problems of post-reversal anxiety seen with high-dose bolus flumazenil (0.1 mg kg-1) were not seen when flumazenil was titrated to effect and 1.0 mg not exceeded.',1 'Four patients with angina and one patient with VT recovered on stopping capecitabine, four patients required additional medical management and the remaining patient died suddenly at home.',1 'Five children in the erythromycin group developed mild diarrhea.',1 'Melphalan reduces the severity of experimental colitis in mice by blocking tumor necrosis factor-alpha signaling pathway.',1 'To decrease infectious complications, lower doses of cyclosporine and oral prednisone than previously reported were used for maintenance immunosuppression in 22 operative survivors of orthotopic cardiac transplantation.',1 'A patient complaining of secondary amenorrhea and hirsutism with elevated levels of plasma total testosterone, dehydroepiandrosterone sulfate, free androgen index and serum inhibin A, and a left ovarian septated, cystic mass was admitted to the hospital.',1 'In bivagotomised, atropinised pithed rats, ranolazine per se evoked marked bradycardia at doses above 10 mg/kg i.v. (maximum variation at 80 mg/kg -125+/-15 bpm, n=6, P<0.001) by a mechanism apparently unrelated to blockade of beta1- or beta2-adrenoceptors.',1 'Epicutaneous, scratch and intracutaneous tests with various penicillins and their major as well as minor determinants were performed on 495 patients either because they were suspected of having a penicillin allergy, or in order to exclude such allergy, or before starting penicillin treatment, or because they suffered from chronic recurrent urticaria.',1 'These results suggest that the relaxation elicited by nifedipine: (1) depends on the strain, with a tendency to be greater in the hypertensive strain; (2) is negatively and positively modulated by endothelium in WKY and SHR, respectively, and (3) is influenced by age, and this influence depends on both the contractile agent and the strain.',1 'The aim of this study was to evaluate whether combinations of quercetin and epigallocatechin 3-gallate (EGCG), flavonoid antioxidants and mesna could prevent cystitis induced by cyclophosphamide, better than mesna alone.',1 'A major criticism is that many of the reported symptoms could be attributable to anemia, which at the time the L-carnitine studies were taking place, was generally being corrected with EPO.',1 'Effects of flurbiprofen on recombinant human IL-1 alpha-induced fever and associated clinical, haematological and blood biochemical changes in the dwarf goat.',1 'At the second level (75 mg/m(2)), two out of two patients experienced dose-limiting toxicities (neutropenia and thrombocytopenia) and no further dose-escalation was attempted, thus an etoposide dose of 50 mg/m(2) was defined as the MTD.',1 'Safety of transvenous temporary cardiac pacing in patients with accidental digoxin overdose and symptomatic bradycardia.',1 'Taking into account the changes in long-term prognosis of lupus nephritis, we reevaluate the role of cytotoxic agents compared to conventional corticosteroid treatment, the choice of immunosuppressive agent (cyclophosphamide, azathioprine, cyclosporine A, etc.), the mode of administration (initial phase/maintenance phase) and the optimal length of treatment.',1 'In the current study, a cost effectiveness analysis was conducted to estimate the economic value of posaconazole as an alternative to Flu/Itra when used to prevent IFI in this patient population.',1 'The incidence of rubeosis in central retinal vein occlusion demonstrating retinal ischemia on fluorescein angiography was 60%, while in patients with central retinal vein occlusion and good capillary perfusion, the incidence of rubeosis only 1%.',1 'The present study was aimed to investigate the anti-atherosclerotic activity of an aqueous extract of Withania coagulans (AWC) in terms of atherogenic index (AI) in normal and streptozotocin (STZ)-induced diabetes.',1 'OBJECTIVE : It has been suggested that the high prevalence of subnormal free testosterone concentrations, along with low or inappropriately normal gonadotropins in men with type 2 diabetes, may be the result of an increase in plasma estradiol concentrations secondary to an increase in aromatase activity in the adipose tissue that leads to the suppression of the hypothalamo-hypophyseal-gonadal axis.',1 'The combined analysis indicated a significant association of rs12762549 in ABCC2 (P = 0.00022) and rs11045585 in SLCO1B3 (P = 0.00017) with docetaxel-induced leukopenia/neutropenia.',1 'In this study, we examined the effects of a specific aurora kinase inhibitor, VE-465, in combination with various conventional anti-leukemia agents, including doxorubicin, daunorubicin, idarubicin, mitoxantron, cytosine arabinoside, vincristine and etoposide, on acute myeloid leukemia cell lines (HL60, U937, THP-1 and KY821), chronic myeloid leukemia cell lines (KCL22, K562 and KU812) and primary leukemia cells.',1 'In this protocol, antigen-specific immunoadsorption to remove existing AB antibodies is used in addition to rituximab to prevent rebound of antibodies and conventional immunosuppression (tacrolimus, mycophenolate mofetil, and prednisolone).',1 'In vitro (7 minus-3H)-testosterone metabolism by the rat ventral prostate effect of some exogenous compounds.',1 'Anti-IL-8 or -FasL antibody, dominant negative TRAF6 (TRAF6-DN), or TRAF6 binding peptide (TRAF6-BP) inhibited doxorubicin-mediated late phase induction of NF-kappaB and diminished cell death.',1 'To assess the influence of calcium channel antagonists on the expression of behavioral sensitization to cocaine, the L-type calcium channel antagonist diltiazem or the N-type calcium channel antagonist omega-conotoxin GVIA was microinjected into the medial nucleus accumbens before a systemic cocaine challenge injection among rats that were previously treated with daily systemic saline or cocaine injections.',1 'Recent studies also have demonstrated that less frequent nocturnal hypoglycemia incidence is associated with insulin glargine compared with NPH insulin.',1 'This case report describes a 54-year-old male on warfarin for atrial fibrillation who presented to the emergency department (ED) following a syncopal episode with persistent hypotension.',1 'After ruling out infectious, parasitic or systemic diseases drug-induced eosinophilic pneumonia was diagnosed due to topical diclofenac therapy and subsequent percutaneous drug absorption.',1 'Post-treatment with propofol slightly, but not significantly, affected the LPS-induced systemic hypotension, tachycardia, leukocytopenia and anaemia.',1 'Immunosuppressive therapy with prednisone did not appear to significantly prolong the course of the B19 infection.',1 'Our study confirmed in this highly specific clinical model the existence of cisplatin peripheral neuropathy: we observed definite clinical signs or symptoms of neuropathy in 80% of patients receiving a cumulative cisplatin dosage of 675 mg/m2; there was a progressive dose-related decrease in SAP amplitudes, expression of a sensory axonopathy or neuronopathy.',1 'The interaction between alpha1-adrenergic and dopamine receptors, especially D1-like and D3 receptors in VSMCs, could be involved in the pathogenesis of hypertension.',1 'METHODS : To explain enhanced sensitivity to AMP in asthma, mast cell expression of the adenosine A2A and A2B receptors and histamine release were measured after incubation of human mast cell line 1 (HMC-1) cells with AMP and the non-specific adenosine receptor agonist 5-N-ethylcarboxamidoadenosine (NECA) for 1.5 and 6 h. To establish a Thelper-2 environment resembling the asthma phenotype, HMC-1 cells were additionally cultured with IL-4 and IL-13 alone or stimulated with the combination of both cytokines and AMP and NECA.',1 'Unfortunately, no effective treatment for established doxorubicin cardiomyopathy is presently available.',1 'Protection of gerbils from amebic liver abscess by immunization with the galactose-specific adherence lectin of Entamoeba histolytica.',1 'Among the 25 patients 55 years old or older, the 16 with involuntary movements were not distinguished from the nine without involuntary movements by past or current exposure to neuroleptics, anticholinergics, or carbamazepine, but they showed poorer cognitive function, had fewer major depressive episodes, and had received briefer exposure to lithium.',1 'While weight loss should be taken into consideration when interpreting cause and effect relationships in streptozotocin-treated animals, epididymal ABP levels appear to be well correlated with the altered metabolic state characteristic of diabetes.',1 'Aglycemia did not elicit neurosecretion in dissociated chemoreceptor cells or in intact CB in culture, but potentiated hypoxia-elicited neurosecretion, exclusively, in 1-day-old intact CB cultures and dissociated chemoreceptor cells cultured for 24 h. In fura 2-loaded cells, aglycemia (but not 1 mM) caused a slow Ca(2+)-dependent and nifedipine-insensitive increase in fluorescence at 340- to 380-nm wavelength emission ratio and augmented the fluorescent signal elicited by hypoxia.',1 'As women with stages I and II operable breast cancer have recurrences of their tumors after exposure to antiestrogen therapy, it is practical to consider treatment with megestrol acetate, whose mechanism of action of killing tumor cells may be different from that of tamoxifen.',1 'Severe hypersensitivity reactions have been reported with bolus injection of heparin contaminated with oversulfated chondroitin sulphate, which has been shown to activate the plasma contact system.',1 'A phase I trial of lomeguatrib and irinotecan in metastatic colorectal cancer.',1 'A withdrawal syndrome after abrupt discontinuation of alprazolam.',1 'Patients with asymptomatic myocardial ischemia are less sensitive to adenosine, whereas patients with Syndrome X are more sensitive with respect to adenosine-provoked pain.',1 'Phase I study of the farnesyltransferase inhibitor lonafarnib with paclitaxel in solid tumors.',1 'In the aspirin induced asthma group there were 66 women (66%) and 34 men (34%).',1 'A total of 1660 hypertensive patients with dyslipidemia received 1 of 15 combinations of amlodipine (placebo, 5, or 10 mg) and atorvastatin (placebo, 10, 20, 40, or 80 mg) in a 3 x 5 factorial randomized, placebo-controlled design.',1 'Primary cultures of hepatocytes isolated from phenobarbital-induced rats were exposed to cocaine (0-1000 microM) for 24 hr, and cell death (apoptosis or necrosis), antioxidant enzyme activities and mRNA levels, and peroxide generation were determined.',1 'Gefitinib prevents bleomycin-induced lung fibrosis in mice.',1 'In the first week of treatment more patients on omeprazole became free of pain in the latter study.',1 'The treatment of doxorubicin nor caffeine, and any treatment schedule did not change the amount and appearance of GLUT 1 as glucose transporter on Ehrlich ascites carcinoma cell.',1 'In order to clarify the degradation of elastin under abnormal conditions, we examined the aortic elastolytic activity in rat experimental diabetes mellitus induced by treatment with streptozotocin and in rat experimental aneurysm induced by treatment with an inhibitor of lysyloxidase (beta-aminopropionitrile: BAPN).',1 'To reverse completely the antidiarrheal effect of equivalent analgesic doses of the opioids (their ED50S for analgesia lasting 2 hours), much more naloxone was required in the case of morphine (5.4 mg/kg) than in the case of fentanyl (0.19 mg/kg).',1 'Plasma concentrations of ghrelin, cortisol, tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta, IL-6, IL-8, soluble IL-2 receptor, C reactive protein, and alpha1-antitrypsin were estimated repeatedly during a 72-hour postoperative period.',1 'BACKGROUND : Malignant idiopathic anaphylaxis refers to the most severe form of idiopathic anaphylaxis where defined episodes of idiopathic anaphylaxis are not controlled when the prednisone is reduced below at least 60 mg every other day or 20 mg daily.',1 'An open multicentre study of tropisetron for cisplatin-induced nausea and vomiting.',1 'Intraduodenal administration of histamine was responsible for the development of an attack of urticaria in 64% of patients, while control subjects were asymptomatic.',1 'This pilot study aimed to evaluate the efficacy and tolerability of a low dose of cabergoline, a D(2) agonist, in the treatment of risperidone-induced hyperprolactinemia.',1 'Medications for anaphylaxis treatment were reported to be available in the 44 responding countries as follows: epinephrine (adrenaline) for injection, 100%; any intravenous glucocorticoid, 89%; any intravenous H1-antihistamine, 77%; any intravenous H2-antihistamine, 70%; glucagon, 73%; atropine, 73%; dopamine, 86%; noradrenaline, 70%; vasopressin, 64%; and a beta 2-agonist for nebulization, 86%.',1 'On the basis of such findings, we propose that the adverse interaction of sulfonylureas and exenatide to induce hypoglycemia involves at least in part, a functional interaction of these two compounds to close K(ATP) channels, to depolarize ß-cells and to promote insulin secretion.',1 'Distinct molecular mechanisms responsible for bortezomib-induced death of therapy-resistant versus -sensitive B-NHL cells.',1 'Dose-limiting toxicities (DLT) were defined as: neutrophils <1000/microl or platelets <50,000/microl before completing administration of etoposide or topotecan; neutropenic fever; platelets <20,000/microl; or a delay greater than 2 weeks in starting cycle 2 due to hematologic toxicity (ANC <1500/microl or platelets <100,000/microl on scheduled day of treatment).',1 'However, a multicenter, randomized, placebo-controlled, double-blind ACTION trial, which compared the effect of long-acting nifedipine or placebo on mortality and cardiovascular morbidity in patients with stable angina, revealed that nifedipine reduced the risk for new-onset overt heart failure by 29%.',1 'Peptide inhibitor or small interfering RNA targeting ER-resident caspase-4 blocked DNA fragmentation, establishing a central role for caspase-4 in bortezomib-induced cell death.',1 'Clozapine, an atypical antipsychotic, has been successfully used in the treatment of psychosis in PD patients.',1 'THE CONTEXT OF OCCURRENCE: Iodine-induced hypothyroidism is observed in fetuses, newborn, adults and in the elderly.',1 'Enhanced sensitivity to tumor necrosis factor-alpha in doxorubicin-resistant tumor cell lines due to down-regulated c-erbB2.',1 'ED50 value of vasodilation for salbutamol (a selective beta-2 agonist) was approximately 80 times greater than that for isoproterenol (a non-selective beta-agonist) in large coronary arteries, but was approximately 20 times in small coronary arteries.',1 'Butyrolactone-I and roscovitine, two Cdk5 kinase inhibitors, were also found to prevent digoxin-triggered LNCaP cell death.',1 'For both heroin/morphine and methadone, deaths were strongly associated with seizures (Spearmans coefficient for males: heroin, P = 0.95, P < 0.001 and methadone, P = 0.83, P = 0.0013).',1 'Administration of heparin can lead to osteoporosis.',1 'D-003 is a mixture of high-molecular-weight acids purified from sugarcane wax which inhibits cholesterol biosynthesis through HMG-CoA reductase regulation, preventing bone loss in osteoporosis induced with ovariectomy and prednisolone in rats.',1 'For immunosuppression, the following subtherapeutic doses were used: calcitriol 0.5 microg/kg/day, cyclosporine A 2.5 mg/kg/day i.p., and tacrolimus 40 microg/kg i.m. Five groups (n = 5) were analyzed: cyclosporine A; cyclosporine A and calcitriol; calcitriol; tacrolimus and calcitriol; and tacrolimus.',1 'In RA patients, the IgG content of galactose was also negatively correlated with the pain index (P less than 0.05) and was lower in the presence of rheumatoid factor (P less than 0.05).',1 'In the antigen-induced arthritis mouse model testosterone had significant inhibitory effects on inflammation (synovial hyperplasia) and cartilage erosion.',1 'Effects of telmisartan on insulin resistance and visceral fat distribution in Chinese hypertensive patients with obesity.',1 'RESULTS : Atrial fibrillation occurred in 3 of 51 patients (5.88%) in the amiodarone group, compared to 24 of 92 patients (26.08%) in the control group.',1 'The incidence of hypoglycemia (minor or major) with concomitant sulfonylurea (exenatide 26.5%, pooled comparator 20.7%) was higher than that without sulfonylurea (exenatide 3.1%, pooled comparator 2.7%) in all groups.',1 '[Thrombopenic purpura and Gougerot-Sjögren syndrome in a woman patient treated by quinidine and beta-blockaders].',1 'In comparison to the potent opioid alfentanil, epidural clonidine produces a similar degree of analgesia but less respiratory depression.',1 'A 52 year old woman is reported who was on long term treatment with chlorambucil and taking a short course of prednisone for familial CLL before she developed progressive dyspnoea, and P carinii pneumonia was diagnosed in bronchoalveolar lavage fluid.',1 'Observations were made of 12 cases of psoriasis that developed and three cases of psoriasis that became exacerbated during treatment with lithium compounds.',1 'Adenovirus-mediated herpes simplex virus thymidine kinase gene and ganciclovir therapy leads to systemic activity against spontaneous and induced metastasis in an orthotopic mouse model of prostate cancer.',1 'Phentolamine, however, abolished the L-NAME-induced hypertension (P < 0.05).',1 'We report the case of a 14-year-old girl in whom doxorubicin-induced cardiomyopathy developed after aggressive therapy for a fibroblastic osteosarcoma.',1 'Bronchodilator reversibility, airway eosinophilia and anti-inflammatory effects of inhaled fluticasone in COPD are not related.',1 'In patients with an increased ulcer risk, postoperative analgesia should be based on paracetamol and tramadol.',1 'PURPOSE : To describe a patient with nonexudative age-related macular degeneration (AMD) who underwent intravitreal pegaptanib sodium injection for drusenoid pigment epithelium detachment (PED).',1 'OBJECTIVES : Docetaxel and pemetrexed have been validated as therapeutics for previously treated advanced non-small-cell lung cancer (NSCLC), but tolerability is a concern for standard treatment with docetaxel administered once every 3 weeks (tri-weekly 75-mg/m(2) schedule).',1 'Confusion and SIRPIDs regress with parenteral lorazepam.',1 'In a first experiment, mice (n = 200) had tacrolimus applied on their dorsal skin three times weekly followed by SSR (2, 4 or 6 standard erythema doses, SED) 3-4 h later.',1 'We conclude that the atypical antipsychotic drug clozapine is helpful in the treatment of tremor in PD and should be considered when all other drug therapies fail.',1 'In 28 breast cyst fluids obtained from 20 patients (age 29-65 years) sodium, potassium and the sulfates (S) of estrone (E1), estradiol (E2), dehydroepiandrosterone (DHEA) and androsterone (A) were determined.',1 'A mild, but statistically significant, increase in conjunctival hyperemia was observed in both latanoprost treatment groups.',1 'Both pantoprazole and placebo resulted in a marked improvement in laryngitis scores (decrease of 8.0 +/- 1.4 versus 5.6 +/- 2.6; no significant difference between the 2 treatments) and symptoms after the first 3 months (decrease of oesophageal symptom score of 2.2 +/- 1.4 versus 5.4 +/- 2.8; decrease of laryngeal scores of 8.3 +/- 3.6 versus 10.3 +/- 3.9; also no significant difference between the 2 treatments).',1 'Overall quality of life is similar with raloxifene or tamoxifen, but the incidence of dyspareunia, weight gain, and musculoskeletal complaints is higher with raloxifene use, whereas vasomotor symptoms, bladder incontinence, gynecologic symptoms, and leg cramps were higher with tamoxifen use.',1 '[Hepatitis caused by fenofibrate].',1 'In this report a case of acute myocardial infarction due to oral amphetamine therapy is presented.',1 'Effects of benazepril and nicardipine on microalbuminuria in normotensive and hypertensive patients with diabetes.',1 'OBJECTIVE : To examine the time course and clinical relevance of changes in prostaglandin E2 (PGE2) to pain and outcome in surgical drainage, and circulating blood after functional endoscopic sinus surgery (FESS).',1 'NGF rescues HMC-1(V560G c-Kit) cells from imatinib mediated cell death and promotes proliferation.',1 'Diarrhea and alanine aminotransferase increases occurred at higher rates in the leflunomide group.',1 'Because the cocaine concentration range we studied is achieved in humans, HERG block may provide an additional mechanism for cocaine-induced arrhythmias and sudden death.',1 'METHODS : Inclusion criteria were laparotomically or laparoscopically documented microscopic or macroscopic (<2 cm) residual disease after first-line chemotherapy including carboplatinum plus paclitaxel in patients with histologically documented epithelial ovarian cancer FIGO stage III or IV at first diagnosis.',1 'Augmentative quetiapine in partial/nonresponders with generalized anxiety disorder: a randomized, placebo-controlled study.',1 'In order to study changes in respiratory sounds associated with acute bronchoconstriction and -dilatation, breath sounds of 11 children with asthma (age range, 10-14 years) were recorded at the chest and at the trachea during histamine challenge test and after subsequent bronchodilatation.',1 'We report a case of acute hemolytic anemia in a 21-year-old Nigerian woman after high-dose misoprostol (4 mg), used for medical abortion.',1 'OBJECTIVES : We evaluated the effect of carvedilol, a nonselective beta-blocker with vasodilating action, on coronary flow reserve (CFR) in patients with idiopathic dilated cardiomyopathy (IDC).',1 'We therefore measured NE, epinephrine (E), and VO2 at rest and during graded maximal treadmill exercise in 24 healthy male volunteers (ages 22-77 yr) from the Baltimore Longitudinal Study of Aging who were rigorously screened to exclude the presence of cardiovascular disease.',1 'BACKGROUND : Atomoxetine is a non-amphetamine medication approved to treat ADHD in children, adolescents, and adults.',1 'Radiotherapy does not influence the severe pulmonary toxicity observed with the administration of gemcitabine and bleomycin in patients with advanced-stage Hodgkins lymphoma treated with the BAGCOPP regimen: a report by the German Hodgkins Lymphoma Study Group.',1 'Principal responses to hemorrhage in rats receiving enflurane were 1) constriction in first-, third-, and fourth-order arterioles, and 2) tissue hypoxia.',1 'Nebivolol reduces experimentally induced warm renal ischemia reperfusion injury in rats.',1 'There does not seem to be a relationship between estrogen dosage and hypertension, while a relationship between progesterone and hypertension seems more possible.',1 'When lipid A was injected in rats pretreated with aspirin or with naloxone, the hypotensive effect was significantly reduced and the decrease in heart rate was reverted in tachycardia.',1 '[Drug-induced hepatitis due to fenofibrate].',1 'Agmatine enhances the anticonvulsant effect of lithium chloride on pentylenetetrazole-induced seizures in mice: Involvement of L-arginine/nitric oxide pathway.',1 'Although weight gain and metabolic adverse events had occurred more often with olanzapine and risperidone during the acute trial, no significant between-drug differences emerged in most of these parameters during maintenance treatment.',1 'Does lithium balance the neuronal bilateral asymmetries in cluster headache?',1 'Administration of methadone, initially as an adjuvant and eventually as the sole analgesic, at a much smaller dose than expected resulted in very satisfactory analgesia, without the development of serious side effects.',1 'Neither the use of atropine nor the induction of ischaemia were associated with an increased incidence of cardiac arrhythmias or hypotension.',1 'The captopril group was associated with hypotension (P < 0.01) but again PRA, HR and RR were not significantly altered.',1 'The following parameters were studied at 0, 6, and 12months: body mass index, abdominal circumference, Ferriman-Gallwey score, presence of acne and acanthosis nigricans, serum testosterone and sex-hormone-binding globulin levels, fasting glucose and fasting insulin levels.',1 'His headache, dementia, and imaging abnormalities abated after treatment with prednisone.',1 'However, ganglionectomized rats were less responsive to amphetamine anorexia than were vagotomized ones.',1 'OBJECTIVES : The purpose of this study was to clarify the cause of decreased metabolic clearance of losartan in patients with end-stage renal failure.',1 'Diabetes was induced in male Wistar rats by a single IV injection of 60mg/kg streptozotocin, and treated groups received 15mg/kg/day metoprolol delivered subcutaneously by osmotic pumps.',1 '[Cholestatic hepatitis caused by D-penicillamine].',1 'Implants with a regime of fibrosis suppression (prednisolone 30 mg daily plus fluphenamic acid 200 mg three times a day for 6 to 8 weeks) controlled the intraocular pressure (applanation tonometry (AT) less than 21 mm Hg) in seven out of ten patients with different types of glaucoma.',1 'Streptozotocin (STZ)-induced diabetes depresses the rate of vascular collagen synthesis in the spontaneously hypertensive rat (SHR), but it also reduces arterial pressure (SAP) in this strain.',1 'In patients with chronic hepatitis C and not with IBS, fatigue scores were negatively correlated with plasma levels of carnitine.',1 'The plasminogen activating factor of tissue detectable by fibrinolysis autography is diminished in varicosis with and without postthrombotic syndrome, in diabetic nephropathy, in viral pneumonia and after short-term cyclophosphamide therapy.',1 'To test the hypothesis that lung sensory C fibers protect the small distal airways and alveoli from oxidant injury, we compared the effects of inhalation of ozone (1 ppm) or filtered air for 8 h on lung injury and lung inflammation in four groups of rats: (1) normal rats exposed to filtered air; (2) normal rats exposed to ozone; (3) rats treated as neonates with capsaicin (50 mg/kg, intraperitoneally) and subsequently exposed to filtered air; and (4) rats treated as neonates with capsaicin and subsequently exposed to ozone.',1 '[Three cases of advanced gastric cancer successfully treated by combination therapy of biweekly S-1 and docetaxel].',1 'Dexmedetomidine as the primary sedative during invasive procedures in infants and toddlers with congenital heart disease.',1 'We describe successful use of immunoablative cyclophosphamide in halting relapses in a patient with systemic lupus erythematosus-associated NMO who was unresponsive to high-dose oral and intravenous corticosteroids, intravenous immunoglobulin, mycophenolate mofetil, tacrolimus, low-dose daily oral cyclophosphamide and rituximab.',1 'Synergistic effect of bortezomib and valproic acid treatment on the proliferation and apoptosis of acute myeloid leukemia and myelodysplastic syndrome cells.',1 'OBSERVATIONS : We report 2 cases of hypersensitivity syndrome induced by the use of sulfasalazine.',1 'Cardiac death, non-fatal myocardial infarction, or target lesion revascularisation occurred in 44 [5%] patients in the everolimus-eluting stent group versus 74 [8%] patients in the paclitaxel-eluting stent group, p value for superiority was 0.005.',1 'OBJECTIVE : An open label study to determine the feasibility and acute toxicity of a 6 month course of outpatient intermittent bolus high dose oral cyclophosphamide in patients with active systemic lupus erythematosus (SLE).',1 'Attenuating effect of mexiletine hydrochloride on herpetic pain in mice infected with herpes simplex virus.',1 'Because of evidence that failure to deliver full dose CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) may compromise the outcome of elderly patients with aggressive non-Hodgkins lymphoma (NHL), we attempted to deliver full dose CHOP to these patients.',1 '[Antihypertensive action and inhibition of tissue conversion enzyme by ramipril, perindopril and enalapril in the spontaneously hypertensive rat (SHRSP)].',1 'Hyperosmolar metabolic acidosis and intravenous Lorazepam.',1 'Pre-existing coagulopathies include antithrombin III deficiency, heparin-induced thrombocytopenia, cancer, factor XII deficiency, hemophilia, idiopathic thrombocytopenic purpura, protein S deficiency, and drug-induced platelet inhibition.',1 'Electron microscopy showed focal fusion of the epithelial cell foot processes that was not described in the previous report of ranitidine-induced interstitial nephritis.',1 'The present study examined further the role of opiates in 2-DG analgesia by examining whether the opiate antagonist, naloxone, would affect 2-DG analgesia, and whether ineffective doses of 2-DG and morphine would interact in a synergistic fashion to induce analgesia.',1 'The predominant amitriptyline adverse experiences were of the anticholinergic type; the predominant mianserin adverse experience was drowsiness/fatigue.',1 'Corneal stromal edema was resolved in response to treatment with topically applied and systemic acyclovir.',1 'Even in the bronchial inflammation and the asthma symptoms are easy to treat with anti-inflammatory medicines, a considerable component of BHR usually still remains, as measured with methacholine or histamine.',1 'In humans, Olanzapine induces weight gain and increases the risk of type 2 diabetes.',1 'Pulmonary complications resulting from use of the drug are uncommon but should be considered in any patient on methotrexate who develops pulmonary symptoms in the absence of infection.',1 'Applying the principle and equipment of patient-controlled analgesia, this double-blind randomised study was designed to determine the premedication dose of midazolam and to provide information about the need for preoperative anxiety control.',1 'OBJECTIVE : The case of a 69-year-old woman taking minocycline for rheumatoid arthritis is presented, and its differential diagnosis discussed in order to characterize the clinical features of minocycline-induced cutaneous pigmentation.',1 'Treatment and management protocols include corticosteroids, methotrexate and other disease-modifying agents such as ciclosporin (cyclosporin) and intravenous immunoglobulin, as well as newer treatments such as tumour necrosis factor blockade or B-cell depletion.',1 'SRL in combination with tacrolimus and/or MMF had no higher incidence of hyperlipidemia than CI and MMF.',1 'Grade 3 esophagitis developed in 4/5 patients on the second dose level of chemoradiotherapy (i.e. vinorelbine 15 mg/m2) and was considered dose-limiting.',1 'Flu syndrome on once monthly rifampicin: a case report.',1 'Effect of high-dose melphalan and peripheral blood stem cell transplantation on renal function in patients with multiple myeloma and renal insufficiency: a case report and review of the literature.',1 'Effects of nebivolol on platelet activation in hypertensive patients: a comparative study with metoprolol.',1 'All children had received naproxen for more than 5 months when pseudoporphyria occurred.',1 'Thus, the well established effect of metformin in reducing insulin resistance makes this drug an excellent candidate for the prevention of progression of impaired glucose tolerance to type 2 diabetes, and for the reduction of mortality associated with cardiovascular disease.',1 'Ulcerative irritant contact dermatitis from lindane.',1 'Cortisol, growth hormone response, and pain following tetracosactrin depot and ACTH gel.',1 'Dipyridamole thallium imaging is useful in the assessment of SMI in elderly patients with Q wave myocardial infarction.',1 'This study examined the effect of experimentally induced fever on the pharmacokinetics of cefepime (75 mg/kg BW) administered intramuscularly to six rabbits.',1 'The authors feel that the reversal of overdose effect of opioid by naloxone after intravascular blood volume expansion puts the patient at risk to develop pulmonary edema.',1 'Empirical monotherapy with meropenem in serious bacterial infections. Meropenem Study Group.',1 'In a randomized cross-over study 10 asymptomatic patients with previous (1-6 years) myocardial infarction underwent two sequential 15-day treatments, respectively, on heparin and on placebo (saline solution), preceded and separated by 10-day wash-out periods.',1 'The overall anxiolytic properties of tianeptine in patients with coexisting depression and anxiety appear to be similar to those of amitriptyline, imipramine and fluoxetine and may be superior to those of maprotiline, although submaximal dosages of amitriptyline and maprotiline were used.',1 'OBJECTIVE : Our purpose was to investigate fetal cerebral blood flow and the incidence of intraventricular hemorrhage in patients undergoing tocolysis with either indomethacin or magnesium sulfate at < 30 weeks gestation.',1 'AIM : To assess efficacy and complications of trans-Tenons retrobulbar infusion of triamcinolone acetonide for posterior uveitic inflammation.',1 'It should be noted that although imipramine is efficient in both depressive disorder and separation anxiety, this does not implicate a common physiopathologic basis.',1 'Peripheral edema was the only adverse event seen more frequently in amlodipine-treated patients.',1 'The adverse reactions occurred both after oral and nebulized administration of N-acetylcysteine, resulting in severe dyspnea and the feeling of drowning.',1 'Anammox (anaerobic ammonium oxidation), which is a reaction that oxidizes ammonium to dinitrogen gas using nitrite as the electron acceptor under anoxic conditions, was an important discovery in the nitrogen cycle.',1 'Three patients with autoimmune hemolytic anemia had macrocytosis (MCV greater than 110 fl) without folate or vitamin B12 deficiency.',1 'Since the amount of necrosis is proportional to dose from about 10(2) to 10(5) mug/kg, while the changes in [Ca](m) are not proportional to dose over this entire range, it is concluded that ISO-induced myocardial necrosis is not mediated exclusively by flooding of heart muscle with plasma-derived calcium, although this is undoubtedly an important factor.',1 'Theophylline treatment was not efficient in preventing HUT-induced syncope in sensitive subjects; however, it prevented dipyridamole-induced syncope in 75% of the moderately sensitive group.',1 'Unlike carcinogen-treated animals with control cell transplants, rats with BEP cell transplants showed rare development of glandular hyperplasia, prostatic intraepithelial neoplasia (PIN), or well differentiated adenocarcinoma with invasion after N-methyl-N-nitrosourea (MNU) and testosterone treatments.',1 'Clinical efficacy has been assessed and proved in over 20 published patient series focussing on patients with acute coronary syndrome with or without myocardial infarction, patients undergoing percutaneous coronary interventions, patients receiving various adjunctive anti-platelet medications, patients with heparin induced thrombocytopenia or patients undergoing cardiac surgery.',1 'CONCLUSION : Long-term exposure to minocycline may be associated with drug-induced lupus.',1 'Efficacy and pharmacokinetics of tobramycin in patients with chronic urinary tract infections and various degrees of renal impairment.',1 'Dexmedetomidine in cardiac surgery patients who fail extubation and present with a delirium state.',1 'Administration of cisplatin to rats induced a marked renal failure, characterized with a significant increase in plasma creatinine and urea concentrations.',1 'First, in rats subjected to 30 min of cardiac ischemia followed by 24 h of reperfusion, carvedilol was administered both pre- and post-ischemia (1 mg/kg, intravenously).',1 'The current findings demonstrate that injections of midazolam produced a regional dissociation of the anxiety-related and motor-related parameters and provide evidence that the stimulant and anxiolytic effects of benzodiazepines are independent phenomena regulated by different central mechanisms.',1 'We measured pica in rats to quantify cisplatin-induced nausea, and to evaluate the antinausea effect of pretreatment with S. baicalensis extract (SbE) given intraperitoneally.',1 'Lactic acidosis is a rare and often lethal complication of metformin therapy.',1 'CPX at a dose of 0.03 mg kg-1 significantly antagonized adenosine-induced bradycardia for up to 2.5 h, while doses of 0.1 and 0.3 mg kg-1 produced significant blockade for periods longer than 5 h. 3.',1 'The objective of this study was to determine the antioxidant activity of a bisbenzylisoquinoline alkaloidal compound (BIQAC) and a series of chemicals, including allopurinol, used clinically for the treatment of chemotherapy-induced mucositis.',1 'Renal failure regressed in both cases on withdrawal of amiodarone and with steroid therapy.',1 'Nonsteroidal antiinflammatory drugs, naproxen, piroxicam, indomethacin, and ibuprofen, significantly delayed the healing of ulcer and acetylsalicylic acid showed no significant effect on the healing.',1 'Individual sera of 3 other patients with heparin induced thrombocytopenia showed considerable variation in the lag phase and rate of platelet aggregation when tested with different normal platelet rich plasma preparations.',1 'This result implies that the increased hemodynamics that occur following the "delay" procedure are effected by prostacyclin, which is a potent humoral factor for vasodilation.',1 'AIM : Studies on the use of intrathecal baclofen (ITB) for ambulant adults with spasticity and/or dystonia of cerebral origin are scarce, and are even more limited for children and adolescents.',1 'Nifedipine for the treatment of high altitude pulmonary edema.',1 'We describe a patient with chronic hypernatraemia (plasma sodium 148-155 mmol/l) and partial nephrogenic diabetes insipidus who had received prolonged lithium treatment.',1 'BACKGROUND : The influence of hypothermia on doxorubicin, cisplatin and radiation cytotoxicity was investigated in vitro.',1 'The study was designed to investigate the role of three proteolytic enzymes viz., chymotrypsin, trypsin and serratiopeptidase on hind paw edema and cotton pellet induced granuloma and their possible interactions with aspirin in albino rats.',1 'All patients given colchicine developed diarrhea after a median time of 24 hours (mean dose of colchicine 6.7 mg).',1 'DEBATE (see Elaldi N et al, Efficacy of oral ribavirin treatment in Crimean-Congo haemorrhagic fever: a quasi-experimental study from Turkey. Journal of Infection 2009; 58: 238-244): Biases and misinterpretation in the assessment of the efficacy of oral ribavirin in the treatment of Crimean-Congo hemorrhagic fever.',1 'The concomitant administration of pethidine (meperidine) and phenobarbitone results in enhanced sedation in a patient previously tolerant of pethidine.',1 'Review: Low-molecular-weight heparin-induced osteoporosis and osteoporotic fractures: a myth or an existing entity?',1 'Combined therapy with weekly irinotecan, infusional 5-fluorouracil and the selective COX-2 inhibitor rofecoxib is a safe and effective second-line treatment in metastatic colorectal cancer.',1 'Cerivastatin induces rhabdomyolysis and acute renal failure.',1 'Interestingly, 9CTT enhanced the differentiation of APL cells induced by ATRA, 9-cis retinoic acid, and synthetic retinobenzoic acids.',1 'These preliminary results suggest that fluoxetine and methylphenidate in combination may be safe and effective for some children with attention-deficit hyperactivity disorder (and with comorbid anxiety or depressive symptoms) who do not show adequate responses to methylphenidate or fluoxetine alone.',1 'Among the studies using a single dose of gabapentin, four did not describe adverse effects; 52.9% showed no differences, 11.8% detected more nausea or vomiting, 5.9% experienced more dizziness, 5.9% more sedation, less nausea or vomiting in one, and less urinary retention in one.',1 'This study compared the effect of single-dose caudal epidural bupivacaine, bupivacaine plus ketamine and bupivacaine plus tramadol for postoperative pain management in children having surgery for inguinal hernia.',1 '3-day treatment with azithromycin 1.5% eye drops versus 7-day treatment with tobramycin 0.3% for purulent bacterial conjunctivitis: multicentre, randomised and controlled trial in adults and children.',1 'High dose oral amiodarone loading exerts important hemodynamic actions in patients with congestive heart failure.',1 'The K. lactis strain harbouring the Klpmr1 disrupted gene is not able to grow in presence of low calcium concentrations and shows hypersensitivity to high concentrations of EGTA in the medium.',1 'We have utilized in vitro and in vivo model systems to examine the biologic processes whereby long-term estradiol deprivation (LTED) causes cells to adapt and develop hypersensitivity to estradiol.',1 'METHODS : Forty-two patients diagnosed with either colonic cancer, diverticulitis, polyps, or adenoma, and scheduled for elective colorectal surgery, were randomly assigned to either postoperative patient-controlled analgesia (PCA) with intravenous morphine (n = 21) or epidural analgesia with a mixture of bupivacaine and fentanyl (n = 21).',1 '[Transient hypothyroidism due to skin contamination with iodine in a newborn infant with an omphalocele].',1 'On this basis we hypothesized that amiodarone-induced alveolar epithelial cell apoptosis and lung fibrosis in vivo might be inhibitable by the angiotensin converting enzyme inhibitor captopril or the angiotensin receptor antagonist losartan.',1 'Here we show that consistent with the vaccinia virus (VACV) and cowpox virus (CPXV) requirement for cytoskeleton alterations early during the infection cycle, PBK/Akt was phosphorylated at S473 [Akt(S473-P)], a modification associated with the mammalian target of rapamycin complex 2 (mTORC2), which was paralleled by phosphorylation at T308 [Akt(T308-P)] by PI3K/PDK1, which is required for host survival.',1 'We are developing tetracyclines as anti-allergy drugs to prevent IgE production, based on our findings that minocycline or doxycycline treatment of allergic asthmatic humans significantly improves their asthma symptoms, reduces their oral steroid requirements, and strongly suppresses their ongoing IgE responses (ELISA, mast cell mediated cutaneous late phase responses); the tetracyclines also strongly suppress peak IgE responses of BPO-KLH sensitized mice (ELISPOT assay, ELISA, skin tests).',1 'CONCLUSIONS : Short-term, intermittent nitroglycerin patch therapy significantly reduces myocardial ischemia, particularly in patients with large ischemic perfusion defects.',1 'We suggest that APT should be considered among the differential diagnosis of hemoptysis in a patient receiving amiodarone.',1 'In conclusion, terfenadine is as effective as chlorpheniramine in the treatment of symptoms of seasonal allergic rhinitis and conjunctivitis with an incidence of sedation not significantly different from that with placebo and significantly less than with chlorpheniramine.',1 'CONCLUSION : Weekly low-dose carboplatin and paclitaxel has significant activity in both platinum-sensitive and platinum-resistant recurrent ovarian cancer with acceptable toxicity that is easily managed by dose adjustment.',1 'Clonazepam-induced incontinence.',1 'Flurbiprofen axetil, a nonselective COX2 inhibitor, is most likely the causative agent in this case, although there are no prior reports of asthma caused by this agent.',1 'Radiation induced early necrosis in patients with malignant gliomas receiving temozolomide.',1 'The formation of a large gastric concretion of nifedipine tablets may have enhanced its local vasodilatory effects thereby producing mesenteric hypoperfusion, ischemia, and infarction.',1 'In this study, we evaluated the effect of intrathecal and oral clonidine as supplements to spinal anesthesia with lidocaine in patients at risk of postoperative alcohol withdrawal syndrome (AWS).',1 'Induced immunosuppression with the drug cyclophosphamide was shown to convert the relatively harmless infection with an avirulent strain of Kunz influenza virus into a fatal pneumonic illness.',1 'The estrogenic activity of tamoxifen is associated with deleterious clinical side effects, including vaginal bleeding, endometrial cancer, and thromboembolism.',1 '[Thrombosis of a cardiopulmonary bypass circuit despite recommended hypocoagulation with danaparoid during the acute phase of type II heparin-induced thrombocytopenia].',1 'Based on the initial measured concentrations, the leflunomide dose was increased to 20 mg/d for several weeks before being reduced to 15 mg due to elevated liver enzymes.',1 'Adrenaline arrhythmia, which is suppressed by Ca channel blockers, was induced by adrenaline infusion in halothane-anesthetized dogs.',1 'A 23-year-old, white male with history of paranoid schizophrenia developed a withdrawal-emergent dyskinesia during a dose reduction of risperidone.',1 'In the cerulein-induced pancreatitis rat model, paclitaxel with dimethyl sulfoxide as a vehicle prevents pancreatitis, suggesting that another causal agent is responsible.',1 'MAIN OUTCOME MEASURES : Outcomes included diagnosis of pneumonia, dispensing of an antibiotic, or hospitalization within 30 days after an ILI diagnosis or oseltamivir dispensing.',1 'A phase I-II, dose-escalating trial of ZD9331 in combination with irinotecan (CPT11) in previously pretreated metastatic colorectal cancer patients.',1 'No calcification was seen at von Kossa staining, confirmed by low calcium content levels of the valve wall and leaflets at atomic absorption spectrometry.',1 'The Cl- secretory response induced by egg albumin during intestinal anaphylaxis was similar to that after addition of 5-hydroxytryptamine (5-HT), histamine, and prostaglandins D2 and E2 to jejunal tissue.',1 'A mechanism for P-glycoprotein-mediated apoptosis as revealed by verapamil hypersensitivity.',1 'Valacyclovir HCl, the L-valyl ester of acyclovir, is an antiviral drug that is used to accelerate the resolution of the herpes zoster rash and associated pain and reduce the duration of postherpetic neuralgia.',1 'CONCLUSION : In this study it was found that CL(VP16) is reduced in patients with elevated serum creatinine, whilst ifosfamide coadministration increases CL(VP16) and reduces AUC(VP16), demonstrating the interaction between VP16 and ifosfamide.',1 'She had been treated with prednisolone, elcatonin and alfacalcidol under the diagnosis of systemic lupus erythematosus (SLE) and aseptic necrosis of femoral bone head.',1 'Gemcitabine induced digital ischaemia and necrosis.',1 'RESULTS : All 13 patients had comorbid Axis I psychiatric disorders along with binge-eating disorder and were receiving psychotropic medications at the time of topiramate administration.',1 'A pravastatin dose-escalation study in systemic lupus erythematosus.',1 'A 75-year old woman with lichen planus, diabetes mellitus, and a foot ulcer was prescribed tacrolimus for the treatment of her lichen planus.',1 'Intravenous diclofenac as prophylactic treatment for verteporfin-associated low back pain.',1 'Prostacyclin mediation of vasodilation following mesenteric traction.',1 'BACKGROUND : Pegylated-interferon (PEG-IFN) and ribavirin (RBV), current standard treatment for hepatitis C virus (HCV) infection, are frequently associated with neutropenia and anemia, leading to high treatment discontinuation rates in HIV/HCV-coinfected patients.',1 'Reversible sensorineural hearing loss with intravenous erythromycin lactobionate.',1 'BACKGROUND : Patients with preoperatively diagnosed type II heparin-induced thrombocytopenia (HIT) scheduled for cardiopulmonary bypass (CPB) present a challenge in their intraoperative anticoagulation management because re-exposure to heparin may result in profound thrombocytopenia, intravascular thromboses, bleeding, and even death.',1 'We examined the mechanism of the inhibitory effect of prostanoid EP(3) receptor agonists on naloxone-precipitated withdrawal syndrome in morphine-dependent rats.',1 'The adrenocorticotropin, corticosterone, prolactin, and renin responses to cocaine are generally unaltered by prior cocaine exposure, suggesting that tolerance or sensitization to the endocrine effects of cocaine does not occur.',1 'Dosages giving optimal sensitization were 25 mg/kg per day for cocaine and 3 mg/kg for WIN 35,065-2.',1 'We therefore used the streptozotocin rat model of short-term diabetic retinopathy to study glial reactivity and other glial functions in the retina in the first months after onset of diabetes.',1 'Pre-treatment with SHPE 7 days before manipulation prevented remifentanil-induced thermal hyperalgesia and mechanical allodynia and the increase in incisional pain observed when surgery was performed under remifentanil anesthesia.',1 'Cortisol and the renal handling of electrolytes: role in glucocorticoid-induced hypertension and bone disease.',1 'Nausea and vomiting, which were most disturbing to the patients, were seen only with buprenorphine.',1 'To investigate UVB DNA damage response in higher plants, we used a genetic screen to isolate Arabidopsis thaliana mutants that are hypersensitive to UVB irradiation, and isolated a UVB-sensitive mutant, termed suv2 (for sensitive to UV 2) that also displayed hypersensitivity to gamma-radiation and hydroxyurea.',1 'However, any hormonal therapeutic strategy must take into account the fact that two almost equivalent sources of androgens act in the prostate, namely testosterone of testicular origin, and the locally produced androgens testosterone and dihydrotestosterone (DHT) derived from dehydroepiandrosterone of adrenal origin.',1 'RESEARCH DESIGN AND METHODS : Long-Evans rats, C57BL/6 mice, and angiotensin II type 1 receptor (AT1-R)-deficient mice with streptozotocin-induced diabetes were treated with (pro)renin receptor blocker (PRRB).',1 'Two compounds 2g and 2k showed more potent anti-inflammatory activity than celecoxib at 5h in carrageenan-induced rat paw edema bioassay.',1 'However, little information is available regarding the mRNA expression patterns of functional molecules, such as T-bet, GATA-3, FOXP3, and retinoic acid-inducible gene-I (RIG-I), in urinary sediment, from patients with immunocomplex-mediated glomerulonephritis.',1 'OBJECTIVE : The aim of this analysis was to compare the effects of 3-year treatment with raloxifene 60 mg/d versus placebo on glycemic control and markers of cardiovascular disease risk in osteoporotic postmenopausal women with and without type 2 diabetes.',1 'Both histamine and betahistine induced reproducible dose-dependent bronchoconstriction in all subjects, as assessed by all measurements made.',1 'Acute doses of imipramine inhibit symptoms of anxiety as well as the exploratory behavior so that the rats appear totally disinterested in their environment.',1 'Effectiveness of prostaglandin E1 for the treatment of patients with neuropathic pain following herpes zoster.',1 'Propofol alone versus propofol in combination with meperidine for sedation during colonoscopy.',1 'The effects of mannitol, methylprednisolone, furosemide, inosine, indomethacin and captopril on the recovery from hydronephrosis were examined in rat kidneys.',1 'RECENT FINDINGS : A number of studies, which initially focused on nociception, also revealed an important role of the peripheral opioid receptor system in opioid-induced bowel dysfunction and pruritus, as well as in wound healing, cardioprotection, and the analgesic effects of celecoxib.',1 'While it is not possible to draw definitive conclusions, further larger studies exploring the use of quetiapine in other delirium populations seem justified.',1 'Effects of physiological levels of estradiol-17 beta and progesterone on oviduct edema and ovum transport in the rabbit.',1 'Prajmalium bitartrate was well tolerated, while three patients receiving procaine amide complained of nausea and gastrointestinal symptoms, so that treatment had to be discontinued in two.',1 'Diarrhea associated with lansoprazole.',1 'Latanoprost may lead a serous retinal detachment in the posterior pole.',1 'Methimazole-induced cholestatic jaundice in an elderly hyperthyroid patient.',1 '[Hypertensive crisis: comparative study of oral captopril, sublingual captopril and sublingual nifedipine].',1 'We studied the effect of maternal diabetes on beta-cell function in the offspring of streptozotocin (STZ)-induced diabetic rat mothers (STZ-offspring).',1 'Five patients in the CA arm and three in the C arm had their planned treatment discontinued owing to progressive disease (n = 3), amifostine side-effects (hypotension, sneezing and sickness, n = 4), and carboplatin-induced thrombocytopenia (n = 1).',1 'RESULTS : Hypotension induced by sevoflurane resulted in a 50% decrease of mean arterial pressure due to a 30% reduction in systemic vascular resistance associated with a 30% decrease in cardiac index.',1 'Controversial risk factors were high-dose NSAID use, concomitant clopidogrel or selective serotonin reuptake inhibitor use, a history of gastrointestinal symptoms, rheumatoid arthritis disability and cardiovascular disease.',1 'Flutamide versus a cyproterone acetate-ethinyl estradiol combination in moderate acne: a pilot randomized clinical trial.',1 'With regard to perioperative dysrhythmias, there was a significantly lower incidence of sinus tachycardia (9%) and atrial flutter/fibrillation (6%) in the NM group as compared to the nifedipine group (33 and 27%, p < 0.05).',1 'CONCLUSIONS : Preharvest immunosuppression with mycophenolate mofetil and tacrolimus significantly decreases immediate posttransplant reactive oxygen species and inflammatory cytokine production, enhances the protective effect of ischemic training, and should not only reduce ischemiareperfusion injury in transplanted kidneys but also should enhance immediate and long-term graft function while preventing acute rejection.',1 'Treatment groups--control (C), ketorolac (5 mg x kg(-1) x d(-1)) (K), large-dose ketorolac (15 mg x kg(-1) x d(-1)) (KH), dehydration-ketorolac (5 mg x kg(-1) x d(-1)) (DK), gentamicin (20 mg x kg(-1) x d(-1)) (G), and gentamicin (20 mg x kg(-1) x d(-1)) with ketorolac (5 mg x kg(-1) x d(-1)) (GK)--each comprised 10 animals.',1 'Incidence rates were similar, except for higher incidence of endocrine disorders in budesonide versus placebo patients (P = 0.0042) caused by a higher overall occurrence of cutaneous GCS symptoms (P = 0.0036) in the budesonide group; differences in individual symptoms were nonsignificant.',1 'Increased renal calcium reabsorption by parathyroid hormone-related protein is a causative factor in the development of humoral hypercalcemia of malignancy refractory to osteoclastic bone resorption inhibitors.',1 'Serum testosterone, luteinizing hormone and follicle stimulating hormone are determined, and it is well to test for diabetes, hypothyroidism, and antisperm antibodies in the partners cervical mucus.',1 '[Effect of propranolol and quinidine on the threshold of experimental auricular fibrillation].',1 'The effect of the selective serotonin reuptake inhibitor citalopram on diabetic neuropathy symptoms was examined in a double-blind, placebo-controlled, crossover study for two 3-week periods.',1 'Methotrexate and its effect on the anti-GAD titre in two patients with rheumatoid arthritis and diabetes mellitus.',1 'CONCLUSIONS : Although the in vitro concentration of cetirizine was required to be quite high, cetirizine may affect in vivo airway inflammation through its inhibition of IL-5-dependent eosinophil survival.',1 'Other medications included furosemide 20 mg/d, ramipril 5 mg/d, clopidogrel 75 mg/d, nitroglycerin patch 0.4 mg/h, and lorazepam 1 mg taken occasionally for agitation.',1 'Antihypertensive action of the novel angiotensin converting enzyme inhibitor benazepril hydrochloride in hypertensive rat models.',1 'Twenty-four patients have kept normal cardiac function, 7 patients had a cardiac toxicity as defined by the institution [4 (24%) of 17 patients received 360 mg/m2 of doxorubicin (A), 2 of 4 presented congestive heart failure (CHF), and 3 (21%) of 14 patients received 240 mg/m(2) of A without CHF].',1 'CONCLUSION : Oral ondansetron had a significant effect in the control of cisplatin-induced delayed emesis and nausea in patients who had not required rescue antiemetics during the acute emesis period.',1 'Sequential methotrexate, 5-fluorouracil, and calcium leucovorin in colorectal carcinoma.',1 '[Pregnancy after treatment of primary sterility with zoladex in patient with essential thrombocytopenia].',1 '[Asthma, nasal polyposis and aspirin intolerance--a triad to remember].',1 'A lower dose of propranolol (2.5 mg/kg) or clofilium (1.5 mg/kg) but not quinidine (10 mg/kg), procainamide (10 mg/kg), or phenytoin (10 mg/kg) also reduced the incidence of ventricular fibrillation.',1 '[Respiratory complications in the course of treatment with D-penicillamine : alveolitis and bronchiolitis. A report of 4 cases (authors transl)].',1 'Anaerobic ammonium oxidation (anammox) is the microbial oxidation of ammonium with nitrite to dinitrogen gas under strict anoxic conditions mediated by planctomycete-like bacteria.',1 'Discontinuation of phenytoin, carbamazepine, and valproate in patients with active epilepsy.',1 'To establish whether chronic opiate use might impair brain dopamine neurons in humans, we assessed dopamine transporter (DAT) uptake function in the striatum (caudate and putamen), and analyzed the correlation between DAT in the striatum and heroin craving and subjective anxiety in former heroin users with prolonged abstinence and in patients receiving methadone maintenance treatment.',1 'These results indicate that the reduction in plasma uric acid caused by allopurinol or oxypurinol does not benefit patients with heart failure.',1 'We measured in vivo hemodynamics and left ventricular (LV) systolic and diastolic function (echocardiograms/Doppler), and ex vivo infarct size (triphenyl tetrazolium chloride), regional AT1R and AT2R proteins (immunoblots), and apoptosis (TUNEL assay and DNA ladder) after regional anterior RMI (60 min ischemia, 90 min reperfusion) in Sprague-Dawley rats randomized to intravenous AT1R blockade with candesartan (1 mg/kg, n = 9) or saline (controls, n = 14) over 30 min before RMI, and sham (n = 8).',1 'CONCLUSION : An increased dosage of cilazapril (twice the maximum recommended dose) in addition to combination therapy with telmisartan was associated with increased blockade of the renin-angiotensin-aldosterone system, with no additional effect on proteinuria, markers of tubular injury or renal fibrosis.',1 'In most patients, allopurinol or any of the potent uricosuric drugs will allow maintenance of normouricaemia but renal failure, renal calculi, transplantation, and allopurinol allergy narrow the options and complicate management.',1 'The second patient did not survive his severe aplastic anemia (with neutropenia) and hemochromatosis (treated with desferrioxamine), complicated with a systemic Rhizopus infection, despite treatment with amphotericin B and granulocyte-colony-stimulating factors.',1 'Furthermore, this bronchoconstriction in the monkey is probably not explained by the action of histamine or mediator release alone and an acute inflammatory reaction may be involved.',1 'RESULTS : Specific antigen administration (4-week repeated dosing) combined with rapamycin and interleukin-10 led to substantial reductions in Teffs, via activation-induced cell death, and induced CD4+CD25+FoxP3+ Tregs to a large extent in multiple organs.',1 'PSAP aggressive responses positively correlated with catecholamines changes, BDHI direct and irritability scores, MMPI psychopathic deviate scores both in methadone subjects and controls, and with CORT responses only in healthy subjects.',1 'The purpose of this study was to test the effect of alendronate in preventing early collapse of the femoral head in patients with nontraumatic osteonecrosis.',1 'Among all patients receiving >or= 1 dose of miglustat (n=28), the most frequent adverse events were diarrhoea, weight decrease, flatulence and tremor.',1 'Therefore, auricular edema and erythema, without fever, fluctuance, and pain, must be recognized by surgeons as a possible mafenide acetate allergy and must be considered in the differential diagnosis for patients who present with recurrent acute suppurative chondritis.',1 'd-Amphetamine sulfate in the treatment of prepartum nausea and vomiting: a two-year study of 150 unwed mothers.',1 'In the post-MI phase, two specific groups of patients benefit from diltiazem or verapamil: (1) those who had non-Q-wave infarcts and (2) those who are hypertensive.',1 'We report a 52-year-old female who developed acute renal insufficiency after administration of one dose of 150 mg of cisplatin for treatment of squamous cell cancer of the esophagus.',1 'Using 0-05 M-tris-HCl buffer, pH 8-0, in the presence of poly-L-ornithine or poly-D-lysine, 50 to 80 % infection was obtained.',1 'OBJECTIVE : To evaluate the efficacy and safety of donepezil for severe Alzheimer disease (AD).',1 'Differences in the rates of hypothyroidism could not be accounted for by differences in age or prior exposure to lithium and/or carbamazepine.',1 'Hyperpigmentation associated with oral minocycline.',1 'Treatment with iloprost for 5 days resulted in highly significant pain reduction.',1 'Micafungin is an echinocandin approved by the European Medicines Evaluation Agency for the treatment of invasive candidiasis in children, including premature infants born before 29 weeks of pregnancy, and as prophylaxis in children undergoing hematopoietic stem-cell transplantation or patients at risk of prolonged neutropenia.',1 'Anticonvulsant activities of diazepam in mice given pentylenetetrazol (PTZ), as well as effects of diazepam against potentiating activities of caffeine on these convulsions, were studied.',1 'Reversible severe neutropenia after ceftriaxone.',1 'The effect of prednisolone suggests that a subsequent antigen-antibody interaction caused by a streptococcal infection may participate in the formation of the purpura.',1 'A major disadvantage of a new cancer treatment, porfimer sodium (Photofrin)-mediated photodynamic therapy (PF-PDT), is photosensitivity for several weeks after cessation of the treatment.',1 'To examine the effect of treatment on lactate-induced anxiety in a controlled study, we infused 44 panic disorder patients with lactate and placebo before and after eight weeks of double-blind treatment with imipramine, diazepam, or placebo.',1 'In this review we discuss fundamental and clinical research which underscores the potential of the testosterone-cortisol ratio as a possible marker for criminal aggressive tendencies.',1 'This program identifies patients using a computerized unit dose system, and is aided by a software able to calculate creatinine clearance using the Cockroft-Gault formula from an interphase between laboratory, pharmacy and admissions data, and by an algorithm to establish a recommended pharmaceutical intervention according to renal failure severity and low molecular weight heparin indication, either with prophylactic or therapeutic purposes.',1 'It is known that significant amount of iodine being incorporated in children or persons with compromised thyroid gland could lead to a number of pathological changes, primarily to autoimmune thyroiditis which is a reason of other consequent pathologies of this organ.',1 'Severe bullous fixed drug eruption due to metronidazole mimicking a localized form of toxic epidermal necrolysis.',1 'Sorafenib may exert its anti-neoplastic effect in part by altering vascular permeability and reducing intra-tumoral interstitial hypertension.',1 'Further large-scale studies of sildenafils effects in women with neurogenic sexual dysfunction are strongly indicated.',1 'Patients in the butorphanol group proved to have less postoperative respiratory depression as determined by arterial carbon dioxide tension on arrival in the recovery room (42.8 mm Hg vs 51.1 mm Hg).',1 'Imipramine in alopecia areata. A double-blind, placebo-controlled study.',1 'This schedule seems to reduce the occurrence of stomatitis of the docetaxel and infusional 5-FU regimen.',1 'Clozapine was used concomitantly to control her psychosis.',1 'Rash mediated by immune complexes associated with ranitidine treatment.',1 'In summary, quinidine inhibited induction of sustained atrioventricular nodal reentrant tachycardia with depression of the retrograde pathway.',1 'The purpose of our study was to clarify whether subtle cortisol-producing tumors, such as not only subclinical Cushings syndrome (SubCS) but also subclinical hypercortisolism (SH), influence the prevalence of hypertension, since numerous basic research studies have noted that glucocorticoid excess influences blood pressure.80 patients with adrenocortical adenomas (39 women and 41 men; mean age 62.1 years) were enrolled.',1 'Solifenacin-induced small bowel pseudo-obstruction.',1 'Some animals also underwent ischemic preconditioning, elicited by either one (IP1) or two (IP2) cycles of 5 min ischemia and 5 min reperfusion, and/or remifentanil, administered either as a transient infusion mimicking the preconditioning protocol (RP2, 10 microg x kg x min) or as a continuous infusion (R, 3-10 microg x kg x min).',1 'Digoxin (1 microM) improved Ca2+-contraction coupling and cooperativity of contraction after but not before ischemia.',1 'TREATMENT AND COURSE : As a drug-induced vasculitis was suspected treatment was started with methylprednisolone, 100 mg daily.',1 'Withdrawal symptoms in long term benzodiazepine users and seizures in patients who have taken an overdose of TCA or carbamazepine and a benzodiazepine can occur with flumazenil; these symptoms are avoidable by utilising slow flumazenil dose titration.',1 'When exploring the importance of the different substances for the cause of death, we found that the detection of some substances, such as fentanyl and morphine, strongly indicated a poisoning, whereas certain other substances, such as benzodiazepines more often were incidental findings.',1 'A phase I study of pegylated liposomal doxorubicin and irinotecan in patients with solid tumors.',1 'The probability of substantial hearing loss was directly related to the cumulative dose of cisplatin.',1 'The clinical signs resolved following radioactive iodine, and the cat subsequently developed clinical hypothyroidism.',1 'Phenytoin dose to ataxia did not change with infusion rate but the total and unbound serum concentrations at onset of ataxia increased with increasing infusion (input) rate.',1 'These results are in contrast with those obtained previously with lidocaine and quinidine, and indicate that the influence of acidosis on class 1 antiarrhythmic agents may also depend on the characteristics of the individual drug.',1 'Acute pancreatitis has been reported in a few cases treated with atorvastatin, fluvastatin, lovastatin, simvastatin and pravastatin.',1 'Role of endogenous morphine in the attenuation of opiate withdrawal syndrome by N-acetylmuramyl-L-alanine-D-isoglutamine (MDP).',1 'Rapamycin (0.5 mg/kg per day) or cyclosporine (5 mg/kg per day) inhibited intimal hyperplasia, medial ECM accumulation and expansive vascular remodelling (increasing vessel circumference) in rat aortic allografts.',1 'METHODS : After obtaining Institutional Review Board approval and informed consent, 50 patients undergoing unilateral TKR were randomly assigned to receive either sufentanil in ropivacaine alone (Group C, n = 25) or the same solution with naloxone (Group N, n = 25) for their postoperative epidural analgesia.',1 'Temozolomide (TMZ) is a DNA methylating agent that has shown promising antitumor activity against high grade glioma.',1 'One patient stopped cevimeline at 4 weeks because of headache and nausea.',1 'Similarly the use of quinidine following cardioversion of atrial fibrillation may be associated with increased mortality.',1 'CONCLUSIONS : Long-term control of blood pressure with perindopril or nifedipine stabilizes AER and attenuates GFR decline in proportion to MAP in non-hypertensive patients with Type 2 diabetes and microalbuminuria.',1 'PURPOSE : The combination of bolus doxorubicin followed by a 3-h infusion of paclitaxel has high antitumor activity in patients with metastatic breast cancer, but is limited by unexpected cardiac toxicity.',1 'Both dipyridamole and exercise-201Tl imaging are sensitive, specific and of prognostic value in patients with suspected coronary artery disease, following myocardial infarction, and undergoing major noncardiac surgery.',1 'Moreover, reflux-induced gastritis was definitely alleviated in the meloxicam group compared with the control group.',1 'Both a low initial serum TSH and a high initial urinary iodine concentration can be predictable factors for a recovery from hypothyroidism due to Hashimotos thyroiditis after restricting their iodine intake.',1 'There was a significant increase in the diverse fear-induced responses caused by bicuculline with the pretreatment of the inferior colliculus with morphine, and the opposite effect was recorded after the pretreatment of the inferior colliculus nuclei with naloxone followed by bicuculline local administration.',1 'Etoposide rapidly induced apoptosis, dependent on caspase-3 and -8, but inhibition of these caspases did not prevent major cell death, but promoted a switch in late morphology.',1 'One trial compared treatment with paclitaxel plus a platinum compound with re-treatment with platinum, and a second trial compared carboplatin plus gemcitabine re-treatment against carboplatin in patients with platinum-sensitive recurrent ovarian cancer.',1 'This case represents a further instance of D-penicillamine-induced cholestatic hepatitis.',1 'A statistically greater number of patients with delirium (CAM-ICU+) received continuous infusions of midazolam (59% vs. 32%, p < .05) or fentanyl (57% vs. 32%, p < .05) and physical soft-limb restraints (77% vs. 50%, p < .05) compared with patients without delirium (CAM-ICU-).',1 'A nonhistone protein having a molecular weight of about 20,000 (20K-NHP), abundantly localized in the dorsolateral prostate, increased rapidly in content during the early stage of sexual maturation (6-11 weeks of age) in association with increases of serum testosterone concentration and prostatic tissue weight.',1 'Adjunctive low molecular weight heparin during fibrinolytic therapy in acute ST-segment elevation myocardial infarction: a meta-analysis of randomized control trials.',1 'Since adequate surgical or hormonal treatment resulted in complete recovery of sexual potency in the majority of patients with varicocele and sexual inadequacy, it is suggested that the decreased testosterone production might have contributed to the impairment of sexual function.',1 'We started argatroban and aspirin to prevent exacerbation of ischemia.',1 'Tacrolimus treatment of mice for 1 week dose-dependently decreased splenic CD4(+)/FoxP3(+) (regulatory T cells), increased splenic CD4(+)/IL-17(+) (T-helper 17) cells, and caused endothelial dysfunction and hypertension.',1 'Continuous intraventricular morphine- or peptide-infusion for intractable cancer pain.',1 'CONCLUSION : In this study of adult Japanese surgical patients, pretreatment with flurbiprofen axetil 50 mg preceded by venous occlusion was found to be more effective in reducing pain on injection of propofol than the other flurbiprofen axetil administration strategies tested.',1 'Rofecoxib-treated L-NAME-hypertensive rats exhibited a significant increase in mean arterial pressure at 6 weeks (168.3+/-5.7 mmHg) as compared with DOCA-hypertensive rats (128.818+/-7.2 mmHg).',1 'An antibiotic combination that includes a proton pump inhibitor such as omeprazole and an antibiotic such as clarithromycin is likely to become the new standard regimen for treatment of Helicobacter pylori gastritis because this combination is extremely effective and very well tolerated.',1 'The incidence of ventricular tachycardia (VT) on ischemia and reperfusion was significantly reduced by captopril and lisinopril.',1 'The effects of different schedules of cocaine administration on circadian activity patterns and locomotor sensitization were studied.',1 'Moreover, the use of capecitabine alone may be insufficient for patients with an intestinal obstruction or perforation.',1 '[Hypersensitivity interstitial pneumopathy and ulcero-hemorrhagic rectocolitis: role of methotrexate].',1 'It seems that the 5-HT1A partial agonist buspirone is of limited value in the treatment of acute neuroleptic-induced akathisia.',1 'CONCLUSIONS : These data, although retrospectively collected, suggest that fludarabine-based chemotherapy is not associated with an increased incidence of infections, in particular IFIs, compared to conventional regimens commonly used for AML induction.',1 'Pharmacologically, this reticular nucleus may be engaged by the centrally-acting antihypertensive agent, clonidine (Catapres, Boehringer Ingelheim), to produce hypotension and bradycardia.',1 'Diffuse alveolar hemorrhage following administration of tirofiban in a patient with acute coronary syndrome: a fatal complication.',1 'BACKGROUND : Substitution of stavudine with zidovudine may lead to recovery from lipodystrophy (LD) in HIV-infected children.',1 'Together, our results demonstrate that bortezomib has significant antiproliferative activity in aggressive bladder cancer cells, which is best exploited within the context of combination chemotherapy.',1 'To study the association between smoking and thyroid disease (Graves disease [E05.0], nodular toxic goiter [E05.2], and autoimmune hypothyroidism [E03.9]) in a low-iodine intake area a case-control study was undertaken.',1 'Treatment with low-dose carbamazepine was successful in abolishing both the paroxysms of nystagmus and the symptoms of vertigo and visual disturbance.',1 'In order to correlate the blood level of testosterone with the degree of erectile dysfunction (ED) and chronic renal failure (CRF) (stage I-V) we selected a group of patients with renal failure on conservative treatment, who attended our nephrology outpatients clinic.',1 'Thrombelastography in a patient with heparin-induced thrombocytopenia treated with argatroban.',1 'We describe a case of rapidly appearing acute renal failure following a single intramuscular dose of ketorolac.',1 'Olanzapine is safe and highly effective in controlling acute and delayed chemotherapy-induced nausea and vomiting in patients receiving highly and moderately emetogenic chemotherapy.',1 'Pretreatment of animals with diazepam (10 mg/kg i.p.) prevented the development of sustained limbic seizures and brain damage caused by morphine, while pretreatment with naloxone hydrochloride (2-20 mg/kg i.p.) failed to affect morphine-induced convulsant activity and brain damage.',1 'After norepinephrine vasoconstriction sufficient to increase renal vascular resistance (RVR) by 50%, the superimposition of 10(-5) M nitrendipine increased the glomerular filtration rate (GFR) of high-salt DS rat kidneys by 125% over control values but returned the GFR of high-salt DR kidneys only to control.',1 'Attenuation of IL-1 beta expression in the hippocampus by chronic exposure to morphine may be one of the mechanisms underlying the neuro-endocrine-immune modulatory effects of opiate addiction.',1 'We recommend caution to be exercised when considering Erlotinib treatment during WBRT, particularly in regard to drug-drug interactions and infection control.',1 'Based on previous observations of cardioplegic ionic myocardial distress, myocardial stress dyskinesia was investigated as another possible cause of exercise stress testing-induced silent myocardial ischemia by analyzing the efficacy of the myocytic calcium channel blocker diltiazem in normalizing the results of patients who previously tested positive.',1 'Women with mild abdominal cramping received amoxicillin plus erythromycin for 1 week; those with severe abdominal pain received amoxicillin plus clindamycin for 1 week.',1 'Modulation of delta9-tetrahydrocannabinol-induced hypothermia by fluoxetine in the rat.',1 'Death from any cause occurred 374 (8.4%) in the simvastatin group and 366 (8.2%) in the atorvastatin group (p = 0.81).',1 'METHODS : The effect of VDM11, an anandamide membrane transporter inhibitor, on capsaicin- and anandamide-induced cough in mice was examined.',1 'Carvedilol was effective in controlling hypertension and preserving renal function in a rat model of progressive hypertensive renal disease.',1 'Heparin-induced thrombocytopenia (HIT) is a life- and limb-threatening prothrombotic, immune-mediated adverse drug effect that occurs with unfractionated heparin and to a lesser extent with low molecular weight heparin.',1 'Intractable hemorrhagic cystitis secondary to radiation or cyclophosphamide (Cytoxan) therapy could lead to serious complications; however, intravesical instillation of phenol has reduced the dilemma of this life-threatening problem.',1 'Both the angiotensin-converting enzyme inhibitor, lisinopril, and the non-steroidal anti-inflammatory drug, indomethacin, lower urinary protein excretion in renal disease and improve the selectivity of the residual proteinuria.',1 'Protocol B induced diabetes using streptozotocin.',1 'EphB receptor signaling in mouse spinal cord contributes to physical dependence on morphine.',1 'Dry mouth was more likely with scopolamine than with meth-scopolamine or cinnarizine.',1 'Maximal morphine-induced physical dependence, measured by jumping during naloxone-induced withdrawal, was observed 3--5 days after implantation.',1 'Anemia was associated with lymphopenia (adjusted OR 4.0, 95% CI 1.36-11.80), high erythropoietin levels (adjusted OR 7.73, 95% CI 2.92-20.48), and low testosterone levels (adjusted OR 3.27, 95% CI 1.01-10.60).',1 'PURPOSE : A case of propofol infusion syndrome in a patient with respiratory failure and sepsis is reported.',1 'Treatment of K562 cells with Ara-C in combination with imatinib mesylate revealed synergistic effects at the level of STAT-5 tyrosine-phosphorylation and DNA binding, Hck tyrosine-phosphorylation, cell growth and induction of apoptosis.',1 'Amiodarone induced a dosage-dependent redistribution of isomyosins similar to hypothyroidism, while simultaneously inducing a low T3 syndrome at the higher dose level.',1 'Doxycycline treatment alone had no effect on lesion scores, whereas the combination of doxycycline and ivermectin resulted in less severe perivascular inflammation.',1 'It was learned that the patient was administered succinylcholine during both of these previous operations and that he did not have a history of prolonged recovery or postoperative apnea.',1 'The effect of nifedipine on serum theophylline levels in 13 female hypertensive patients having asthma on theophylline therapy has been investigated.',1 'BACKGROUND : The purpose of the study was to evaluate first-line platinum/paclitaxel (Taxol) under phase III trial conditions in ovarian cancer (OC) patients aged >or=70 years.',1 'This retrospective study was conducted to determine whether the addition of a third injection of biphasic insulin aspart 70/30 (BIAsp 30) just before lunch in older patients with type 2 diabetes who did not achieve goals with a twice-daily (BID) regimen would optimize glycemic control in a clinical practice setting.',1 'Both 15-HPAA (1-20 micrograms ml(-1) min (-1)) and 13-hydroperoxy linoleic acid (13-HPLA, 20 micrograms ml(-1) min(-1)) caused a marked enhancement of the anaphylactic release of histamine, slow-reacting substance of anaphylaxis (SRS-A) and rabbit aorta contracting substance (RCS) from guinea-pig isolated perfused lungs.',1 'Selegiline treatment in chronic heart failure animals reduced plasma norepinephrine, cardiac oxidative stress and myocyte apoptosis, prevented the changes of Bcl-2 and Bcl-2 to Bax ratio, and improved left ventricular fractional shortening and dP/dt.',1 'To reverse completely the antidiarrheal effect of equivalent analgesic oral doses of the opioids (their ED50S for analgesia lasting 2 hours), more naloxone was required in the case of morphine (11 mg/kg) than in the case of fentanyl (2.0 mg/kg).',1 'Fondaparinux is the alternative to LMWH in people after major orthopaedic surgeries and with a history of heparin induced thrombocytopenia over the past three months.',1 'We hypothesized that pulmonary toxicity can be diagnosed more readily when these scans indicate the presence of increased attenuation of either pleural or pulmonary densities representing high iodine amiodarone deposits.',1 'Methylprednisolone (MP) was evaluated for the treatment of intracerebral hemorrhage in a Sprague-Dawley rat model of cerebral hematoma induced by subcortical injection of collagenase.',1 'In a group of rats with streptozotocin induced diabetes the excretion of calcium, magnesium, phosphorus and creatinine in urine was investigated and the calcium, magnesium and phosphorus content of bone in relation to the duration of the disease.',1 'METHODS : Postmenopausal women with breast cancer who were receiving tamoxifen, with ultrasonographic endometrial thickness greater than 4 mm or vaginal bleeding, had hysteroscopy with selective endometrial biopsies.',1 'In the Zoladex versus orchiectomy trial, there was no significant difference between the treatment groups with regard to subjective and objective responses (British Prostate Group criteria), endocrine responses, clinical effects and side effects, time to treatment failure and death, or survival after similar median follow-up periods.',1 'Oral lamotrigine did not reduce secondary hyperalgesia or acute thermal nociception but produced side effects of severity comparable with that of oral hydromorphone.',1 'AUTHORS CONCLUSIONS : Rofecoxib 50 mg (two to four times the standard daily dose for chronic pain) is an effective single dose oral analgesic for acute postoperative pain in adults, with a relatively long duration of action.',1 '[Acute pancreatitis following azathioprine therapy of crohns disease--a case report and the overview of the literature].',1 'Indomethacin lessened disease severity (parasite burden and pathology), and promoted a Th1 response, but the mice still succumbed to infection.',1 'BACKGROUND : Fluticasone furoate nasal spray (FFNS), an intranasal corticosteroid, has been shown to be effective in perennial allergic rhinitis in randomized, double-blind, placebo-controlled studies but has been less extensively studied in perennial allergic rhinitis than seasonal allergic rhinitis.',1 'Multivariate logistic regression analysis revealed that serum magnesium concentration was a significant independent factor associated with the presence of vascular calcification in hemodialysis patients (odds ratio 0.28, 95% CI 0.09 - 0.92/1 mg/dl increase in serum magnesium, p = 0.036) after adjustment for age, gender, duration of hemodialysis, calcium, phosphate and intact parathyroid hormone concentrations.',1 'Thymidine-cisplatin vs thymidine-carboplatin interactions in human T-cell acute leukemia.',1 'Remission-inducing chemotherapy and symptomatic treatment of hypercalcemia corrected the serum calcium.',1 'We report two children who developed mycolonic seizures and had abnormal electroencephalograms when oxcarbazepine was introduced.',1 'Melphalan-induced supraventricular tachycardia: incidence and risk factors.',1 'Tacrolimus was significantly superior to oil-based cyclosporine with regard to hypertension (RR 0.66; 95% CI 0.54-0.80, p < 0.0001), and hyperlipidaemia (RR 0.57; 95% CI 0.38-0.87, p = 0.009).',1 'AIM : To evaluate the efficacy and tolerability of ketoprofen (a non-steroidal anti-inflammatory drug) plus interferon alpha (group B) compared to interferon alpha plus ribavirin (group C) and interferon alpha alone (group A) in chronic hepatitis C non-responders after a 5-month course with interferon alpha.',1 'The effect of hysterectomy or levonorgestrel-releasing intrauterine system on lower abdominal pain and back pain among women treated for menorrhagia: a five-year randomized controlled trial.',1 'CONCLUSIONS : Because pentoxifylline restored the depressed CO and tissue perfusion and decreased the susceptibility to sepsis, this agent appears to be a useful adjunct to crystalloid resuscitation after trauma and hemorrhage, even in the absence of blood resuscitation.',1 'PURPOSE : A Gynecologic Oncology Group (GOG) randomized phase III trial (GOG 172) in optimal stage III epithelial ovarian cancer showed that intravenous (IV) paclitaxel plus intraperitoneal (IP) cisplatin and paclitaxel significantly lengthened progression-free survival and overall survival compared with IV paclitaxel and cisplatin.',1 'The hazard ratio for death of men treated with cabazitaxel compared with those taking mitoxantrone was 0·70 (95% CI 0·59-0·83, p<0·0001).',1 '[Safety of Sildenafil in men with cardiovascular diseases].',1 'These data support the view that hypertension and hypotension in dysautonomia are related to the rate of norepinephrine release.',1 'AEBM (270 mg/kg) in indomethacin and iodoacetamide induced colitis significantly reduced the ulcer score and myeloperoxidase (MPO) activity.',1 'We hypothesized that a steroid-free immunosuppression with rapamycin and tacrolimus may have contributed to changes in the portal microenvironment.',1 'Spatial and temporal evolution of neuronal activation, stress and injury in lithium-pilocarpine seizures in adult rats.',1 'ULCERATIVE COLITIS: In ulcerative colitis, these are steroid dependency, the maintenance of remission in chronic active ulcerative colitis and the maintenance of remission after induction of remission with cyclosporin or tacrolimus in acute attacks of disease.',1 'BACKGROUND : Optic neuropathy has been reported to occur during antiarrhythmic therapy with amiodarone.',1 'Hypoxia increased the release and overflow of endogenous norepinephrine.',1 'The effect of citalopram hydrobromide on 5-HT2A receptors in the impulsive-aggressive dog, as measured with 123I-5-I-R91150 SPECT.',1 'This case demonstrates that clomipramine-induced urinary retention is not limited to older individuals.',1 'RESULTS : Ten of the 11 patients received clopidogrel for 14 days or less before the onset of thrombotic thrombocytopenic purpura.',1 'Furthermore, the absence of change in substance P-like immunoreactivity in the enteric system of rats with streptozotocin-induced diabetes of the same duration suggests that calcitonin gene-related peptide and substance P are contained in different populations of intrinsic nerve fibers in the gastrointestinal tract of the rat.',1 'To examine the effects of baclofen and SKF 97541 on the expression of cocaine sensitization, the drugs were given acutely before a challenge dose of cocaine (10 mg/kg) on day 10.',1 'Our case suggests that a transesophageal echocardiographic examination can be useful in the early diagnosis of heparin-associated thrombocytopenia and thrombosis.',1 'Effects of topical nitroglycerin and intravenous lidocaine on propofol-induced pain on injection.',1 'Sudden death from superior mesenteric artery thrombosis in a cocaine user.',1 'METHODS : A two-stage phase II trial was designed for patients with advanced ovarian cancer with progressive disease despite prior treatment with platinum and paclitaxel.',1 'An open randomized study was conducted in mild to moderate hypertensive patients to evaluate, over a 3 months treatment period, the efficacy and tolerability of carvedilol 25 mg OD and to compare, in case of insufficient results with 25 mg, the efficacy and tolerance of carvedilol 50 mg and carvedilol 25 mg coadministered with diuretics.',1 'Perhaps the best-documented beneficial effect of B is on calcium (Ca) metabolism or utilization, and thus, bone calcification and maintenance.',1 'Twenty hypertensive men, aged 58 to 62 years, who had been treated with a combination of different drugs for many years, had their therapy changed in a stepwise manner to a combination of 50 mg of atenolol per day and 2 to 15 mg of prazosin per day.',1 'Midazolam itself does not exhibit analgetic action, but its application allows to break through the circulus vitiosus anxiety-tension-pain.',1 'Adriamycin (doxorubicin) is a potent and broad-spectrum antineoplastic agent, the clinical utility of which is limited by the development of a cumulative and irreversible cardiomyopathy.',1 'RESULTS : Indinavir therapy averaged 5.7 months prior to presentation with renal colic.',1 'The progression of Taxol-induced mechanical hypersensitivity coincides with loss of intraepidermal nerve fibers, and the hyperalgesia and nerve fiber loss were prevented with minocycline treatment.',1 'Ischemia-induced expression of several inflammatory cytokines and chemokines was markedly reduced in rosiglitazone-treated brains, as determined using proteomic-array analysis.',1 'Amlodipine-induced reduction of oxidative stress in the brain is associated with sympatho-inhibitory effects in stroke-prone spontaneously hypertensive rats.',1 'Progesterone has been used in the hormonal treatment of endometrial cancer (EC) for many years, but the response rates are unsatisfying.',1 'CASE SUMMARY : A 24-year-old woman was admitted to the hospital because of convulsions, severe myopathy, and acute renal failure after taking ciprofloxacin for sinusitis, and urinary tract infections.',1 'Shock, seizures, cardiac arrhythmias, and respiratory and cardiac arrests developed in a patient who ingested 8.5 g of theophylline.',1 'HeartMate II implantation in patients with heparin-induced thrombocytopenia type II.',1 'Muscle weakness gradually improved after cyclophosphamide therapy.',1 'Relief of cough and nasal symptoms associated with allergic rhinitis by mometasone furoate nasal spray.',1 'We observed that ischemia-induced learning impairment assessed in the Morris water maze, and microglial activation visualized by immunocytochemistry, were prevented by diazoxide as determined at 13 weeks after 2VO.',1 'The etiology of valproic acid-induced thrombocytopenia has not been elucidated.',1 'In addition to the inhibition of serum protein-mediated coagulation, heparin inactivates or prevents the release of mediators of vascular injury inflammation, permeability, and edema.',1 'AIMS : The present study was to determine whether prenatal cocaine exposure induced apoptosis and the possible role of Bcl-2 family genes in the programming cell death in fetal rat brain.',1 'Further research may provide more information, such as which headache types best respond to lidocaine, if higher concentrations of lidocaine are more effective, if lidocaine solution is more effective than lidocaine nose spray, and if other local anesthetics are as effective.',1 'A comparison of fosinopril and hydrochlorothiazide with hydrochlorothiazide in non-insulin-dependent diabetes mellitus patients with mild to moderate hypertension.',1 'Frequent varicella zoster reactivation associated with therapeutic use of arsenic trioxide: portents of an old scourge.',1 'Signal-averaged electrocardiogram (ECG) variables were analyzed in 81 patients with ventricular tachyarrhythmia and nonischemic heart disease using the ART LVP 101 EPX system (Austin, TX): 15 ventricular tachycardia patients with arrhythmogenic right ventricular dysplasia (ARVD), 7 ventricular tachycardia patients with dilated cardiomyopathy, 25 patients with "idiopathic" verapamil-sensitive left ventricular tachycardia, 24 patients with "idiopathic" right ventricular tachycardia, and 10 "idiopathic" ventricular fibrillation (IVF) patients with rbbb pattern and ST-segment elevation in the precordial leads.',1 'The development of delayed doxorubicin cardiomyopathy in the rat is accompanied by profound anorexia, dramatically reducing the caloric intake.',1 'We describe a severe case of warfarin-induced skin necrosis with extensive full-thickness tissue loss involving approximately 12 per cent of the body surface area.',1 'For this, C57BL/6J mice were pre-treated with PPA (0-40 mg/kg) during postnatal days 35-44, and the capacity of cocaine (4 x 15 mg/kg) to elicit a conditioned place-preference, as well as behavioral and neurochemical sensitization within the NAC, were then assessed in adulthood.',1 'The potentiation of SNP-induced hypotension by sildenafil may be related to an augmented accumulation of cGMP.',1 'At the dose administered, dexamethasone was unhelpful for chronic pain after cholecystectomy and did not result in suppression of the sympathetic nervous system as assessed by urinary excretion of NE.',1 'Both Ang II-induced superoxide anion and LTC(4) generation were decreased in control cells by pertussis toxin and fluvastatin (Flu), whereas in each patient group, mepacrin, verapamil and Flu were effective, suggesting alterations in signal pathways, which may be attributed to isoprenylation.',1 'The present results show that adenosine A2ARs and DA D3Rs exert inhibitory actions on acute locomotor responses to cocaine and on the expression of cocaine sensitization, while DA D2Rs had an opposing role in such effects.',1 'This case reported to a patient with AIDS who presented persistent sterile leukocyturia and hematuria, lower back pain, bladder suffering symptoms, and renal papillary necrosis which were thought to be secondary to urinary tuberculosis but were demonstrated to be indinavir-associated side effects.',1 'Because, in our experience, several patients with primary biliary cirrhosis (PBC) claimed that sertraline had improved their pruritus, we sought to determine whether sertraline use was associated with changes in pruritus medications or self-reported severity of pruritus in a large cohort of patients with PBC.',1 'RESULTS : The first patient is a 10-year-old boy who had been treated unsuccessfully for a left vernal corneal ulcer with topical prednisolone 0.5% and olopatadine.',1 'Significant morphine-induced analgesia was observed in both pain models and was reversed by naloxone but unaffected by buspirone.',1 'While intrathecal injection of ACPT-I, a selective group III mGluR agonist, failed to induce any change in vocalization thresholds of healthy animals submitted to mechanical or thermal stimuli, it dose-dependently inhibited the nociceptive behavior of rats submitted to the formalin test and the mechanical hyperalgesia associated with different animal models of inflammatory (carrageenan-treated and monoarthritic rats) or neuropathic pain (mononeuropathic and vincristine-treated rats).',1 'The spinal ischemia-induced allodynia was not relieved by morphine, but it was relieved by the gamma-aminobutyric acid (GABA)-B receptor agonist baclofen, indicating that the allodynia may be related to dysfunction of the spinal GABA-ergic inhibitory system.',1 'These observations were compared with findings in age- and gender-matched subjects who died from cocaine overdose and in patients who had sudden cardiac death (acute thrombosis) without a history of illicit drug abuse.',1 'In vivo in streptozotocin-diabetic rats, selected agents at 20 mg/kg/day, orally for 21 days reduced significantly the sorbitol levels of rbc, lens and sciatic nerves, suggesting that these derivatives may have some usefulness to treat clinical complications of diabetes mellitus.',1 'Thus, enhanced levels of catecholamines or histamine could be involved in the development of receptor-specific changes in the lymphocyte adenylate cyclase system of allergic patients with asthma.',1 'Effect of naloxone infusion on analgesia and respiratory depression after epidural fentanyl.',1 'AIM : To investigate whether mitochondrial calcium uniporter participates in the cardioprotection of tumor necrosis factor alpha (TNFalpha) pretreatment in isolated rat hearts subjected to ischemia/reperfusion.',1 'Reported complications after tacrolimus conversion included hyperglycemia, hyperkalemia, lymphoproliferative disorder, infection, and neurologic problems.',1 'Glucose-stimulated insulin secretion was maintained in transgenic mice, which were resistant to streptozotocin-induced diabetes.',1 'Thrombocytopenia associated with human immunodeficiency virus (HIV) is well described, and two recent reports show a beneficial effect with the antiretroviral agent zidovudine (ZDV).',1 'This study monitored cardiac siderosis using T2* MRI in a cohort of 19 heavily iron-overloaded patients with beta-thalassemia major receiving iron chelation therapy with deferasirox over an 18-month period.',1 'METHODS : Data were obtained from three sources: 1) the time course of skin photosensitivity in 17 volunteers by measuring erythema/edema over time after verteporfin, using red light exposure; 2) the duration of skin photosensitivity in 30 patients with skin cancer by exposing skin to simulated solar light and calculating the daily minimal erythematous dose; and 3) the incidences of photosensitivity reactions as recorded in three phase III trials in patients with CNV secondary to age-related macular degeneration or pathologic myopia who received the regimen of verteporfin therapy currently approved by regulatory authorities (infusion of 6 mg/m(2) body surface area).',1 'Effect of dexamethasone on experimental cerebral infarction in the gerbil.',1 '[Studies of renal function in diabetes insipidus treated with hydrochlorothiazide].',1 'Patch test study with calcipotriol ointment in different patient groups, including psoriatic patients with and without adverse dermatitis.',1 'Seizures occurred in 3 of 29 patients (10.3%) who were receiving 4 g/d of imipenem, in 3 of 136 patients (2.2%) who were receiving cefoperazone plus piperacillin, in 0 of the 132 patients who were receiving ceftazidime plus piperacillin, and in 1 of 106 patients (0.9%) who were receiving 2 g/d of imipenem (P less than 0.005).',1 'The patient had prominent gastrointestinal symptoms, splenic infarction, splenomegaly with hypersplenism, and hemophagocytic histiocytosis in the spleen and lymph nodes; the organism displayed growth on Campy-selective blood agar, thermotolerance, and resistance to quinolones, piperacillin/tazobactam, ceftazidime, and erythromycin.',1 '5-fluorouracil and gemcitabine potentiate the efficacy of oncolytic herpes viral gene therapy in the treatment of pancreatic cancer.',1 '[Infantile hypothyroidism caused by iodotyrosine-dehalogenase deficiency. II. Results of iodine treatment in 5 cases (8 years of recession in 1 case].',1 'We describe three patients with RA who developed cirrhosis while taking low dose methotrexate (MTX).',1 'OBJECTIVE : In the present study, immunohistochemical parameters for proliferation, differentiation, inflammation, and apoptosis were investigated in a group of bexarotene-treated psoriatic patients.',1 'Because Graves disease remitted, PEG-IFN-alpha plus ribavirin treatment was started for chronic hepatitis C. She was examined because of complaints of general fatigue, weight loss, and palpitations after 24 weeks of the treatment.',1 'An unusual pattern of testosterone metabolism in tissue associated with a keratin-filled cutaneous cyst.',1 'RESULTS : Overall 13 studies examined the use of risperidone, olanzapine, and quetiapine, two cases were reported about ziprasidone, and no publication was found using aripiprazole in the treatment of delirium.',1 'After treatment with intavitreal methotrexate the subretinal lesions disappeared, but corneal epitheliopathy, macular edema, and cotton wool spots appeared in both eyes.',1 'In this study, we have tested the effect of cilostazol on the development of vascular inflammation in rats with streptozotocin-induced diabetes and determined the mechanism by which cilostazol prevents diabetes-induced vascular inflammation in the aorta.',1 'Melphalan-total body irradiation and autologous bone marrow transplantation for adult acute leukemia beyond first remission.',1 'There was no difference between amiodarone and the remaining compounds in patients suffering from ischaemic heart disease, congestive heart failure and chronic obstructive lung disease.',1 'CASE PRESENTATION : In a case of metastatic adenocarcinoma of the gastroesophageal junction, the progression of bone metastasis was observed during a chemotherapy regimen of epirubicin, oxaliplatin and capecitabine, whereas lung-, liver and lymph node metastases as well as the primary tumor were regressing.',1 'The two-compound formulation of calcipotriol and betamethasone dipropionate for treatment of moderately severe body and scalp psoriasis - an introduction.',1 'CONCLUSIONS : In this model, clonidine given prophylactically delays the toxic manifestations of bupivacaine overdose and does not accentuate the subsequent hypotension.',1 'Dimaprit (0.1-30 mumol/kg i.v.) did not modify heart rate but caused a modest bradycardia at 100 mumol/kg i.v. Amthamine (1-100 mumol/kg i.v.) induced a dose-dependent tachycardia, which was only partially (approximately 20%) reduced by famotidine and was totally blocked by propranolol (0.3 mg/kg i.v.).',1 'PURPOSE : To determine the risk ratios and incidence of intraoperative floppy iris syndrome (IFIS) during cataract surgery in patients using tamsulosin, and to assess management strategies for IFIS.',1 'RESULTS : Based on the 95% confidence intervals for the incidences of breast cancer, and the Fisher exact test, there is no indication of a difference between the levonorgestrel system users and average Finnish female population in any of the 5-year age groups.',1 '[Bilateral hematoma of the adrenals and thrombopenia induced by heparin].',1 'An 18-year-old patient is described who presented with febrile neutropenia and hepatitis caused by minocycline therapy.',1 'We hypothesized that stress-induced release of norepinephrine in the BSTL modulates anxiety-like behavioral responses to stress and activation of the hypothalamic-pituitary-adrenal stress axis.',1 'A special group is comprised of essential hypertension with renin suppression, which is associated with a relatively high level of urinary excretion of dopamine as compared with noradrenalin.',1 'Dapsone also causes a mononucleosis-like syndrome.',1 'The usefulness of the serum calcium, parathyroid hormone, chloride, phosphorus, serum 25-OHD, and 1,25-(OH)2D, and urinary calcium in the differential diagnosis of hypercalcemia is discussed.',1 'We believe that mucositis was a contributing factor to this case of fatal hyperkalemia after administration of succinylcholine, with a mechanism similar to that reported with thermal injury.',1 'Most of these studies have serious limitations, however; until better studies have been completed, the decision to use clozapine for Parkinsons disease-related psychosis should be made on a case-by-case basis, with thorough evaluation of risks, benefits, and other therapeutic options.',1 'Doses of 50-200 micrograms/kg medetomidine alone or 30-125 micrograms/kg medetomidine combined with greater than or equal to 300 micrograms/kg ketamine induced complete immobilization, good muscle relaxation and persistent, deep sedation with little respiratory depression in NR; SR required higher doses.',1 'The results indicate that sequential use of midazolam and propofol for long-term sedation could reduce the incidence of agitation compared with midazolam alone.',1 'Successful use of zonisamide for central poststroke pain.',1 'Heparin-induced thrombocytopenia II-induced critical limb ischaemia treated with urokinase and argatroban.',1 'RESULTS : Pruritus, tenderness, and erythema were resolved in all 3 patients after 7 to 10 consecutive days use of tacrolimus 0.075% ointment in conjunction with avoidance of topical steroids, caffeine, spicy food, alcohol, hot fluids, and fluoride.',1 'In the present study we have examined the effects of three different lymphocyte- and macrophage-derived cytokines--tumor necrosis factor alpha (TNF alpha), interleukin-1 beta (IL-1 beta), and interleukin-2 (IL-2)--on the production of ovulatory mediators such as prostaglandins and progesterone in the preovulatory follicle of the eCG/hCG-primed immature rat.',1 'Therapeutic equivalence of a novel HFA134a-containing metered-dose inhaler and the conventional CFC inhaler (Berodual) for the delivery of a fixed combination of fenoterol/ipratropium bromide. A randomized double-blind placebo-controlled crossover study in patients with asthma.',1 'Objective: To investigate the specific effect of adjunctive aripiprazole on sexual function in patients with major depressive disorder and a history of an inadequate response to antidepressant medication by controlling for improvement in depressive symptoms as measured by improvement in Montgomery-Asberg Depression Rating Scale (MADRS) total scores.',1 'We noted that the delirium resembled serotonin toxicity and that the patient had been taking paroxetine until 2 days before surgery.',1 'BACKGROUND : The role of testosterone on the development of coronary artery disease in men is controversial.',1 'Iodine-induced thyroiditis in the non-obese diabetic (NOD) mouse--more questions than answers.',1 'METHODS : Plasma concentrations of adenosine, norepinephrine, and tumor necrosis factor-alpha relating to the pathogenesis of preeclampsia were measured in women with mild (n = 21) and severe (n = 21) preeclampsia and normal pregnancies (n = 21), matched for age, gestational age, and parity, in the third trimester of pregnancy.',1 'In this case report, even a moderate dose of dexmedetomidine, a very selective alpha(2)-adrenergic agent, resulted in a rapid response to alcohol withdrawal delirium after the standard treatment.',1 'Concomitantly, leakage of the macromolecule fluorescein isothiocyanate-dextran (5 mg in 0.1 ml saline i.v., M(r) 150,000) into the perivascular space increased from 0% before ischemia to approximately 12% at 0.5 h reperfusion.',1 'METHODS : In 1991-1994, 50 patients having refractory cancer pain were treated with a continuous intrathecal infusion of morphine using an external pump with patient-controlled boluses.',1 'Thirty-three of the 44 patients who received ketamine showed signs of systemic absorption (blurred vision, sedation) within 10 min of injection.',1 'Sustained effect of the aromatase inhibitors anastrozole and letrozole on endometrial thickness in patients with endometrial hyperplasia and endometrial carcinoma.',1 'Initial results of this investigation suggest that topical glycopyrrolate in concentrations 0f 0.5% and 1.0% provide complete effective control of gustatory sweating for at least several days duration after a single application.',1 'Phase II/III trials in patients with previously treated or untreated metastatic colorectal cancer, including those with documented refractory disease, demonstrate activity of the monoclonal antibody cetuximab (Erbitux) as a single agent or in combination with both irinotecan (Camptosar)- and oxaliplatin (Eloxatin)-based chemotherapy.',1 'The dose of peptides and of morphine in the physical dependence test was determined from the AD50 to inhibit the tail-flick test in rats.',1 'Sequential magnetic resonance imaging analysis of celecoxib-fed mice documented lower prostate volume compared with the AIN 76A-fed group.',1 'The present study compared in a clinical non-experimental setting the efficacy of buprenorphine (BUP) and methadone (METH) in the treatment of opioid dependence: all the subjects included in the study showed severe long-lasting heroin addiction.',1 'Headache, dyspepsia, and flushing were the most common adverse events in sildenafil-treated patients.',1 'In the rabbit model of S. aureus keratitis, following the treatments, the median number of CFU of recoverable bacteria for chlorhexidine (n = 10), ciprofloxacin (n = 12), tobramycin/cefazolin (n = 12), and controls (n = 10) was 1.1 x 10(3), 4.7 x 10(4), 1.9 x 10(5), and 6.7 x 10(4), respectively.',1 'RESULTS : There were no significant interactions between drug assignment and number of capsules in the proportional hazards analyses of time to all cause discontinuation (p=.77, excluding ziprasidone and .74 in the ziprasidone cohort) or in the mixed model analysis of PANSS symptoms (p=.49), quality of life (p=.45); or measures of tardive dyskinesia (AIMS, p=.47).',1 'In conclusion, intraoperative dexmedetomidine infusion attenuated the hemodynamic and neuroendocrinal response to surgical trauma and cardiopulmonary bypass in pediatric patients undergoing corrective surgery for congenital heart disease.',1 'The mean percent tumor necrosis for dogs receiving radiation therapy plus IA cisplatin or radiation therapy plus IV cisplatin was 83.7% and 78.2%, respectively.',1 'Cocaine produced higher ambulatory and non-ambulatory activity in animals pre-exposed to neurotensin than in the vehicle pre-exposed animals, a sensitization effect that was not prevented by CPP at 1 week post-training but that was blocked at 3 weeks at the high dose.',1 '[Serum digoxin levels and echocardiographic indices of myocardial contractility in acute ischemic heart disease].',1 'RESULTS : Atovaquone-proguanil was stopped for 3/48 children because of vomiting.',1 'Further supporting the relationship between sexual dysfunction and antidepressant mechanism of action, data from a number of studies indicate that bupropion, nefazodone, and mirtazapine alleviate symptoms of sexual dysfunction and are as effective as SSRIs at controlling depressive symptoms.',1 'Hypertrichosis in females applying minoxidil topical solution and in normal controls.',1 '[Cortisone therapy of a hirsutism goiter hyperthyroid syndrome; determination by fractionation of urinary 17-ketosteroids].',1 'OBJECTIVE : To report a case of postnatal, postoperative amiodarone-induced hypothyroidism in an infant with a congenital heart defect.',1 'Concentrations of 2 X 10(-9) to 2 X 10(-8) mol/L 1,25(OH)2D3 and 10(-8) to 10(-7) mol/L retinoic acid had a stimulatory effect on myeloid colony growth in five of the six patients with sideroblastic and refractory anemia, but in only two of the 11 patients with refractory anemia with excess of blasts and chronic myelomonocytic leukemia.',1 'We evaluated the effect of pregabalin in the treatment of uraemic pruritus not due to secondary hyperparathyroidism.',1 'Catheter ablation vs. amiodarone plus losartan for prevention of atrial fibrillation recurrence in patients with paroxysmal atrial fibrillation.',1 '[Effects of electroacupuncture pretreatment on ischemic arrhythmia and intracellular calcium oscillation in single cardiocyte isolated from rats with myocardial ischemia and reperfusion].',1 'The authors critically examined the relationships among anxiety, anxiety disorders, tobacco use, and nicotine dependence and reviewed the existing empirical literature.',1 'Neither d- nor l-verapamil in concentrations that exert a profound negative chronotropic effect or cause AV block, has any significant effect on transatrial or His bundle conduction.',1 'In addition, heparin-associated thrombocytopenia developed in 13 of the 23 LA patients (56.5%) and in none of the control patients.',1 'When groups of female albino mice, pretreated with cyclophosphamide, were exposed to quinidine 100 mg/kg i.p. followed by 0.1 J/cm2 UVB and 5.0 J/cm2 UVA, a positive challenge reaction, measured as ear edema, could be registered as early as the third day after induction and peaked on days 5-12.',1 'The condition was worsened by pilocarpine; however, atropine and cyclopentolate opened the angle and deepened the anterior chamber, resulting in resolution of the malignant glaucoma.',1 'The utility of methadone and morphine for analgesia and of methadone for substitution therapy for heroin addiction is a consequence of these drugs acting as opioid receptor agonists.',1 'Routine elective penicillin allergy skin testing in children and adolescents: study of sensitization.',1 'Most AEs were mild to moderate and transitory; discontinuation of topiramate was observed in 13 patients (4.1%) as a result of AEs such as impaired memory (seven patients [54%]), paraesthesias (four patients [31%]), and weight loss and cutaneous reaction (each one patient [7.5% each]).',1 'As increased sedation and impaired psychomotor and cognitive functions often occur, a number of studies have investigated the use of amphetamine derivatives to counteract the sedative side-effects of opioid.',1 'The MAC of halothane decreased significantly during hypotension in all three groups: in the pentolinium group from a control MAC of 1.2 +/- 0.14 (SEM) to a MAC of 0.7 +/- 0.11 during hypotension, in the trimethaphan group from a control MAC of 1.02 +/- 0.06 to a MAC of 0.72 +/- 0.07 during hypotension, and in the nitroprusside group from a control MAC of 1.02 +/- 0.07 to a MAC of 0.73 +/- 0.07 during hypotension.',1 'METHODS : After diabetes was induced by injection of streptozotocin (STZ), the rats were divided into two subgroups.',1 'Absence of cochleotoxicity measured by standard and high-frequency pure tone audiometry in a trial of once- versus three-times-daily tobramycin in cystic fibrosis patients.',1 'To develop a model system for evaluation of chemotherapy-related fatigue, we studied mice treated with either a commonly used formulation of the chemotherapeutic agent paclitaxel (paclitaxel; Taxol), which is known to have neurotoxic properties, or a nano- particle formulation of paclitaxel (nab-paclitaxel; Abraxane) that is reported to have greater potency and efficacy yet fewer side effects than does paclitaxel.',1 'The effect of cadmium administration in vivo on plasma testosterone and the ultrastructure of rat lateral prostate.',1 'We describe a patient with delayed-onset HIT triggered by low-molecular-weight heparin (LMWH) which occurred during fondaparinux prophylaxis and which was complicated by microangiopathic hemolytic anemia.',1 'Iatrogenic chest pain: a case of 5-fluorouracil cardiotoxicity.',1 'In a double-blind randomized parallel-group study, six investigators enrolled 43 subjects to study the prophylactic effect of 10 mg cetirizine b.i.d. on grass pollen-induced asthma.',1 'Chlormadinone acetate decreased testosterone and dihydrotestosterone but finasteride decreased only dihydrotestosterone in the prostate gland.',1 'There were no significant changes in blood pressure, cortisol, pain, nausea, or fatigue.',1 'Therefore, we hypothesize a beneficial effect of atorvastatin on NO-dependent vasodilation in patients with type 2 diabetes and mild dyslipidemia (low density lipoproteins >4.0 mmol/L and/or triglycerides >1.8 mmol/L).',1 'Patients with left ventricular ejection fraction (LVEF) < 40%, symptoms of heart failure or angina class III and IV, severe diseases and DAP > or =110 mmHg during the four-week wash-out with atenolol treatment alone, were excluded.',1 'The immunosuppressant azathioprine (or its metabolite, 6-mercaptopurine) is considered an efficient maintenance therapy for Crohns, but there is always concern about bone-marrow suppression, liver damage, and other adverse effects.',1 'Propofol shortens the action potential duration (APD) but lessens the ischemia-induced decrease in the APD.',1 'A selective diagnostic approach by laboratory measures should exclude any confusion with heparin-induced thrombocytopenia and pseudo thrombocytopenia.',1 'Rosiglitazone improved GI, insulin sensitiveness, and adiponectin immunostaining, but it resulted in body weight gain, hyperphagia, and adipocyte and heart hypertrophy.',1 'Five patients developed hypertension (increases greater than 20% over the baseline value), which was controlled with additional sufentanil or a vasodilator.',1 'During chemotherapy, the side effect and complications were tolerable, and she experienced only grade-1 nausea caused by 5-fluorouracil.',1 'CONCLUSIONS : The sequence of carboplatin/paclitaxel administration does not exert a significant influence on the level of observed neutropenia.',1 'Efficacy of nimesulide versus meloxicam in the control of pain, swelling and trismus following extraction of impacted lower third molar.',1 'Although all-trans retinoic acid (ATRA) has been shown to improve the outcome of patients with acute promyelocytic leukemia (APL) compared with chemotherapy alone, various adverse effects have been reported.',1 'The presentations were (1) 4-Methylpyrazole as a tool in the investigation of the role of ADH in the actions of alcohol in humans, by Taisto Sarkola and C. J. Peter Eriksson; (2) ADH2 polymorphism and flushing in Asian populations, by Wei J. Chen, C. C. Chen, J. M. Ju, and Andrew T. A. Cheng; (3) Role of ADH3 genotypes in the acute effects of alcohol in a Finnish population, by Hidetaka Yamamoto, Kathrin Kohlenberg-Müller, and C. J. Peter Eriksson; (4) Clinical characteristics and disease course of alcoholics with different ADH2 genotypes, by Mitsuru Kimura, Masanobu Murayama, Sachio Matsushita, Haruo Kashima, and Susumu Higuchi; (5) ADH2 polymorphism, alcohol drinking, and birth defects, by Lucinda Carr, D. Viljoen, L. Brooke, T. Stewart, T. Foroud, J. Su, and Ting-Kai Li; and (6) ADH genotypes and alcohol use in Europeans, by John B. Whitfield.',1 'A single injection of lorazepam (1 mg/kg i.v.) blocks the first type of myoclonus but favors the appearance of the second.',1 'A stable, mild diabetes in rats maintained on a normal laboratory diet was induced by a single i.p. injection of streptozotocin.',1 'Our purpose here is to argue in favor of combined mild hypothermia (35 degrees C) and magnesium as an acute neuroprotective treatment to minimize ischemic brain injury.',1 '(1) The action of benazepril on the progression of renal failure in non diabetic patients has been assessed in a comparative placebo-controlled trial involving nearly 600 patients, most of whom were hypertensive.',1 'Experimental colitis studied by colonoscopy in the rat: effect of indomethacin.',1 'However, the increased use of mefloquine over the past decade has resulted in reports of rare, but severe, neuropsychiatric adverse reactions, such as anxiety, depression, hallucinations and psychosis.',1 'AIM : To demonstrate the hypothesis that dexamethasone (Dex) could improve chronic heart failure (CHF) by inhibiting the downstream signaling transduction of leptin but had no influence on the upregulation of leptin and its receptor in myocardium.',1 'Fevers, rigors, myalgias, and fatigue were partially alleviated by premedication with acetaminophen or hydrocortisone.',1 'To investigate whether lithium carbonate, propranolol or chloroquine aggravate psoriasis through influencing cytokines of the psoriatic cytokine network, HaCaT keratinocytes were stimulated with TNF-a after treatment with these drugs.',1 'Skin necrosis developed in rats injected with doxorubicin concentrations ranging from 0.02 mg/ml to 2 mg/ml.',1 'There was one case of CMV colitis in the ganciclovir group, whereas four cases of CMV syndrome, three cases of CMV pneumonia, and one case of CMV hepatitis developed in the acyclovir group.',1 '[Echocardiographic and electrocardiographic evaluation of the effects of propranolol and verapamil in obstructive hypertrophic cardiomyopathy].',1 'METHODS AND RESULTS : Sixty patients (53 +/- 10 years) with essential hypertension were randomized to 6 weeks of double-blind therapy with either valsartan (80 mg), hydrochlorothiazide (HCTZ) (25 mg), or placebo once daily.',1 'In hypobaric and anoxic hypoxia the interaction of cinnarizine with the effect of prostacyclin (PGI2) was investigated.',1 'CASE REPORT : A 48-year-old woman with refractory diabetic cystoid macular oedema underwent successive intravitreal triamcinolone injections, which were followed by a progressive thinning of the neurosensory retina at the fovea, and then by a full-thickness macular hole, associated with a perifoveal posterior hyaloid detachment, visible on OCT.',1 'Risperidone in the treatment of acute mania: double-blind, placebo-controlled study.',1 'With regard to persistent pulmonary hypertension in newborns, enoximone was also used in piglets to investigate the effects on endotoxin-induced, dopamine-resistant pulmonary hypertension.',1 'Association studies showed that the A(-444)C polymorphism was weakly associated with asthma per se, but there was no association between the C(-444) allele and chronic asthma severity or aspirin intolerance.',1 'We have examined the chronic haemodynamic effect of combined captopril and hydrochlorothiazide treatment at rest and during 50 and 100 W dynamic exercise in 12 patients with severe therapy resistant essential hypertension.',1 'Warfarin for refractory chronic cluster headache: a randomized pilot study.',1 'METHODS : Relevant articles were identified through a PubMed search of clinical trials and postmarketing surveillance studies of vardenafil in patients with ED including those with diabetes, hypertension and dyslipidaemia.',1 'The histamine release was significantly higher in the asthma group (both responders and nonresponders) than in the healthy control group.',1 'Alpha2-adrenoreceptor mediated sympathoinhibition of heart rate during acute hypoxia is diminished in conscious prostacyclin synthase deficient mice.',1 'We describe two patients with treatment-resistant schizophrenia characterized by unremitting delusions, thought disorder and self-neglect who had a sustained improvement in their symptoms soon after starting risperidone.',1 'When orally administered to genetically obese and diabetic yellow KK mice (2.4-24.5 mg/kg/d), and Zucker fatty rats (0.1-10 mg/kg/d) for 4 days, pioglitazone markedly decreased hyperglycemia, hyperlipidemia, hyperinsulinemia, and glucose intolerance characterized as insulin resistant states in these animals.',1 'In addition, well-conducted studies using verapamil and diltiazem have suggested that these calcium antagonists may even improve cardiovascular mortality and morbidity of the hypertensive patient.',1 'BACKGROUND : The Thrombolysis in Myocardial Infarction (TIMI) 8 trial was undertaken to compare the efficacy and safety of bivalirudin versus unfractionated heparin in a double-blind phase III trial of patients with unstable angina/non-ST-elevation myocardial infarction (MI).',1 'Although calcium (Ca) precipitation may play a pathogenic role in atherosclerosis, information on temporal patterns of microcalcifications in human coronary arteries, their relation to expression of calcification-regulating proteins, and colocalization with iron (Fe) and zinc (Zn) is scarce.',1 'BACKGROUND : Propofol and droperidol decrease the incidence of postoperative nausea and vomiting (PONV).',1 'In vivo, APL patients treated with oral all-trans retinoic acid (all-trans RA) alone achieve complete remission in 80% of the cases.',1 'Minor side effects of iloprost administration are represented by facial flushing, tachycardia, headache, nausea, vomiting, abdominal cramping, diarrhoea, whose frequency ranges from 16% to 70%; major collateral effects, occurring in less than 5% of patients, are above all represented by severe hypotension and angina pectoris.',1 'OBJECTIVE : To study the effect of methylprednisolone (MP) and cyclophosphamide (CPA) intermittent intravenous pulse therapy and the clinical prognosis in children with severe juvenile onset systemic lupus erythematosus (JOSLE).',1 'In a comparison of the patients who received azithromycin with those who received erythromycin, there was no significant difference (P >.05) in the reduction of pain at any time of the study.',1 'A blinded observer collected data on maternal sedation, lightheadedness, hemodynamics, oxygenation, and fetal heart rate over a one-hour period following sufentanil injection.',1 'We describe a case of unusually severe acute tubular necrosis occurring in an adolescent with cystic fibrosis receiving i.v. gentamicin plus ceftazidime and discuss the possible mechanisms.',1 'The potentiation of seizures and death by 2 mg/kg nifedipine pretreatment was further shown by challenge with three different doses of cocaine.',1 '[Effects of nebivolol, metoprolol and enalapril maleate on the state of endothelium-dependent arteriolar vasodilation in patients with essential hypertension].',1 'INTRODUCTION : This study was designed to determine the short-term effect of acetyl-l-carnitine (ALC) on symptoms of withdrawal in opiate-dependent subjects and animals and, in particular, on pain, given the efficacy of ALC in other typologies of pain.',1 '[2 new liquid forms of clobetasol propionate in seborrheoic eczema].',1 'Some years ago a buprenorphine formulation for transdermal therapy of chronic cancer-related and non-cancer-related pain became available.',1 'Morphine is recommended by WHO as the analgesic of choice for effective treatment of moderate to severe cancer pain .',1 'OBJECTIVE : To explore the significance of combined therapy of arsenic trioxide (As2O3) and all-trans retinoic acid (ATRA) in acute promyelocytic leukemia (APL).',1 'OBJECTIVE : To study the effects of severe renal failure and haemodialysis on the pharmacokinetics of citalopram.',1 'The most common adverse events associated with topiramate are paresthesia, weight loss, and other centrally mediated symptoms, many of which may be ameliorated by proper titration and dosing and by good communication between physician and patient.',1 'Plasma IL-6, tumor necrosis factor-alpha, norepinephrine (NE), endothelin-1, atrial and brain natriuretic peptide, and cyclic guanosine monophosphate (cGMP) levels were determined.',1 'Identification of independent risk factors for fentanyl-induced cough.',1 'Lethal gastroenteritis associated with clozapine and loperamide.',1 'Circadian pattern of arrhythmic death in patients receiving encainide, flecainide or moricizine in the Cardiac Arrhythmia Suppression Trial (CAST).',1 'CONCLUSION : In the absence of risk factors for manic switch, sertraline-induced hypomania may be a true side-effect of drug.',1 'Duloxetine and hyponatremia: a report of 5 cases.',1 'Fluvoxamines most common adverse effects were nausea and agitation.',1 'Although quinidine has been reported to induce QT interval prolongation and torsades de pointes clinically, the only experimental model currently available for quinidine-induced torsades de pointes requires the concurrent use of ischemia, reperfusion and cardiac pacing of the isolated, perfused heart.',1 'This study examines prevalence rates for DSM-III-R anxiety and affective disorders in three follow-up samples of opioid addicts who were treated with methadone maintenance.',1 'Ketoprofen 50 mg may be considered an effective and well tolerated analgesic in the treatment of episodic tension-type headache of moderate or severe intensity.',1 'However, more amitriptyline-treated patients reported decreased visual accommodation, dry mouth, dyspepsia, constipation, tachycardia, hypertension, hypotension, discoordination, dizziness, and tremor than mirtazapine- or placebo-treated patients.',1 'These results suggest that aggravation of neuronal necrosis by chronic dexamethasone pretreatment could be ascribed to lactic acidosis due to hyperglycemia in combination with an action of dexamethasone on glucocorticoid receptors in the brain.',1 'One patient reported symptoms of myalgia after conversion to rosuvastatin; however, the conversion protocol did not require obtaining creatine kinase values.',1 'Raloxifene, another of these drugs, is being used to prevent osteoporosis in postmenopausal women, but it seems, like tamoxifen, to prevent breast cancer.',1 'in aquagenic pruritus of polyglobulins, therapeutic efficacy of aspirin raises suspicion of involvement of prostaglandins.',1 '[Hemorrhagic colitis caused by penicillin].',1 'Though daily oral treatment with dexamethasone reduced the increased numbers of these cells, it did not affect the dry skin symptoms or the prolonged scratching episodes.',1 'CONCLUSION : Long-term indomethacin treatment during pregnancy may lead to the development of renal failure and irreversible renal damage with cystic dilatation of developing nephrons in an exposed fetus.',1 'Score changes on this instrument have been used to report statistically significant treatment advantages for a low-dose oral contraceptive (Estrostep, containing norethisterone (norethindrone) acetate (NA) 1mg and ethinylestradiol (EE) [20, 30, 35 mg] as compared with placebo in women with moderate acne vulgaris.',1 'However, subjects with no family history of hypertension had significantly higher plasma norepinephrine levels (p less than 0.01) than did those with a family history during both the alcohol and placebo phases, although baseline blood pressures were not significantly different.',1 'Despite the lack of any published evidence, the New York Heart Association issued a warning about using caution when prescribing pregabalin to type III-IV heart failure patients.',1 'We report the case of a 70-year-old man who developed hypothyroidism associated with TSH receptor antibodies and severe ophthalmopathy during lithium therapy.',1 '[The development and safety of cough provocation test by capsaicin inhalation].',1 'Effect of timolol on exercise-induced reduction in regional ejection fraction in patients with coronary artery disease.',1 'Medical castration leads to decreased production of testosterone and dihydrotestosterone by the testes, but adrenal glands and even prostate cancer tissue continue to produce androgens, which eventually leads to continued prostate cancer growth despite castrate level of androgens.',1 'In SHR treated with amiodarone, the low-frequency oscillations of AP were lower (8.5+/-1.2 mm Hg(2) versus 14.4+/-2.9 mm Hg(2) in control SHR, P<0.05), whereas the reflex bradycardia was higher (0.84+/-0.12 ms/mm Hg versus 0.32+/-0.22 ms/mm Hg in control SHR, P<0.05).',1 'METHODS : One hundred-sixty consecutive patients with biopsy-proven H. pylori infection were randomized to receive lansoprazole 30 mg b.i.d. on days 1-4, azithromycin 500 mg u.i.d. on days 2-4, and tinidazole 2000 mg u.i.d. on day 3 (LAT group), or 7 days of triple therapy of omeprazole 20 mg u.i.d., clarithromycin 250 mg b.i.d., and tinidazole 500 mg b.i.d. (OCT group).',1 'Answer Similar to valproic acid, carbamazepine increases the risk of neural tube defects; however, it does not increase the risk of other malformations.',1 'After achieving adequate analgesia with regular dosing of oral methadone (T1), patient-controlled analgesia with methadone was administered for 3 days (T2).',1 'Among patients with a history of congestive heart failure (CHF), 14.8% of the propranolol-treated patients experienced definite CHF during the study, as did 12.6% of the placebo-treated patients.',1 '[Cyclophosphamide induced amenorrhoea in pre-menopausal women with systemic lupus erythematosus].',1 'Independent of the digoxin dose, the digoxin concentrations in the choroid plexus tended to be lower in persons treated for a short time before death than in those treated for longer periods of time.',1 'BACKGROUND : Vardenafil is a new phosphodiesterase-5 inhibitor that has shown some efficacy in the treatment of pulmonary arterial hypertension (PAH).',1 'Some patients present prolonged apnea following the administration of succinylcholine because of substantial portion of plasma cholinesterase (the enzyme responsible for the hydrolysis of this muscle relaxant) is present as an atypical variant.',1 'Parasite and fever clearance times were shorter for the group treated with mefloquine but the differences were not statistically significant.',1 'The authors conclude that among elderly patients with heart failure, lower triiodothyronine concentrations are more prevalent and are associated with a worse prognosis.',1 'Although in some cases the action of bradykinin is entirely mediated by the endothelial release of nitric oxide (NO) and/or prostacyclin (PGI2), a large amount of evidence has been accumulated during the last 10 years indicating that a non-NO/PGI2 factor accounts for bradykinin-induced vasodilation in a wide variety of perfused vascular beds and isolated small arteries from several species including humans.',1 'Nevertheless in this case of posterior leaflet prolapse with annular calcification valve repair was performed, after complete calcium debridement causing annulus disruption and atrio-ventricular discontinuity, by means of a straddling atrio-ventricular pericardial patch and the sliding leaflet technique.',1 'Electromyographic recordings from antagonistic flexor and extensor muscles in the forelegs (biceps and triceps) and hind legs (tibialis and gastrocnemius-soleus) of freely moving rats demonstrated that haloperidol (5 and 10 mg/kg, i.p.) and morphine (20 and 40 mg/kg, i.p.) produced contrasting patterns of rigidity.',1 'The occurrence of epistaxis is followed by premature discontinuation of clopidogrel therapy by one fifth of patients after coronary angioplasty and DES implantation.',1 'Multiple drug interactions in a renal transplant patient leading to simvastatin-induced rhabdomyolysis: a case report.',1 'We report the case of a 77-year-old man admitted nine days after being commenced on azathioprine with symptoms initially thought to be secondary to sepsis but in fact due to azathioprine hypersensitivity.',1 'Withdrawal of CsA, tacrolimus, or MMF during year 2 was also associated with an increase in the risk of graft loss compared with continuing treatment (hazard ratio 1.52-1.73).',1 'In contrast, motoneurons cultured in the absence of muscle extract die within 48 h. This death can be blocked by the RNA synthesis inhibitor actinomycin D, at the time when the cells become committed to die, suggesting that new gene expression is required for cell death.',1 'In cases of intravitreal injection of triamcinolone, the main differential diagnosis is pseudoendophthalmitis, an aseptic inflammatory reaction with hyalitis and hypopyon, which occurs within 3 days and spontaneously resolves.',1 'A prospective, randomized, double-blind, concurrent, placebo-controlled clinical trial of intravenous ribavirin (loading dose of 33 mg/kg, 16 mg/kg every 6 h for 4 days, and 8 mg/kg every 8 h for 3 days) was conducted in 242 patients with serologically confirmed hemorrhagic fever with renal syndrome (HFRS) in the Peoples Republic of China.',1 'Dissociation of histamine release and clinical improvement following treatment of acquired cold urticaria by prednisone.',1 '[Pharmacologic effects and safety profile of bethanechol in the differential diagnosis of pseudo-anginal thoracic pain].',1 'Risperidone has proven efficacy with reduced likelihood of causing extrapyramidal symptoms in the treatment of schizophrenia.',1 'Long-term clarithromycin decreases prednisone requirements in elderly patients with prednisone-dependent asthma.',1 'In both groups the plasma GH levels were inversely correlated with the birds age and body weight and directly correlated with the percentage weekly weight gain Plasma GH concentrations in the testosterone treated birds were higher than in the controls at 4 weeks of age and lower at 3, 6, 7, 8, and 9 weeks of age.',1 'No differences in hemodynamics or coronary collateral blood flow (radioactive microspheres) were observed between groups before and during ischemia and reperfusion, except that infusion of sildenafil produced transient decreases in left ventricle systolic pressure.',1 'Less core hypothermia when anesthesia is induced with inhaled sevoflurane than with intravenous propofol.',1 'METHODS : To better understand mechanisms of drug resistance, and possibly identify novel targets for therapy, we generated a series of drug resistant ovarian cancer cell lines through repeated exposure to three chemotherapeutic drugs (cisplatin, doxorubicin, or paclitaxel), and identified changes in gene expression patterns using Illumina whole-genome expression microarrays.',1 'The concerns about testosterone therapy in ageing men with late-onset hypogonadism mainly address the risk of prostatic disease, i.e. either benign prostatic hyperplasia (BPH) or prostate cancer (PCa).',1 'Comparative effects of propranolol and chlordiazepoxide in anxiety states.',1 'Severe loss of vision after removal of cataract caused by intravitreal triamcinolone in combination with photodynamic therapy for exudative age-related macular degeneration.',1 'Nitroglycerin vasodilation served as control.',1 'D-Cycloserine is a partial agonist of the strychnine-insensitive glycine site that inhibits the tonic hindlimb extension (THE) component of maximal electroshock seizures (MES).',1 'Urinary testosterone and 3 alpha-androstanediol (3 alpha diol G) glucuronides together with plasma testosterone, 5 alpha-dihydrotestosterone (DHT), and delta 4-androstenedione (delta 4) were measured in 43 normal young men (18-36 yr old), 23 elderly men without clinically evident prostatic pathology (54-89 yr old), 68 elderly men with benign prostatic hyperplasia (BPH group; 54-91 yr old), and 26 elderly men with well differentiated cancer of the prostate (K group; 63-97 yr old).',1 'One death by cocaine and two by MDMA were caused in the time observed.',1 'CONCLUSION : The authors observed that Padexol was as good as the other paclitaxel (Taxol or Genexol) formulations when combined with cisplatin for treating patients with advanced NSCLC.',1 'Streptozotocin-induced diabetes mellitus causes changes in primary sensory neuronal cytoskeletal mRNA levels that mimic those caused by axotomy.',1 'Omeprazole and excessive sweating.',1 'Gabapentin for the prevention of chemotherapy- induced nausea and vomiting: a pilot study.',1 'Renal failure & hyperkalemia have been reported in patients receiving triamterene & indomethacin.',1 'To evaluate the continuing benefit of long-term zoledronic acid therapy, retrospective exploratory analyses were conducted based on the incidence of skeletal-related events (SREs; defined as pathologic bone fracture, spinal cord compression, surgery or radiation therapy to bone, or change in antineoplastic therapy for bone pain) occurring only during the extension phase of this trial.',1 'These results suggest that primarily peripheral, rather than central, mechanisms are involved in the hypotensive effects of bromocriptine.',1 'Life-long administration (greater than or equal to 2 years) of a number of long-acting gastric acid inhibitors (including H2-receptor antagonists, omeprazole and ciprofibrate) has been associated with the development of gastric enterochromaffin-like cell (ECL cell) carcinoids in rats.',1 'Further cases of valvular heart disease associated with fenfluramine-phentermine.',1 'Particular interest in this gene family is stimulated by the fact that the SLC26A2, SLC26A3, and SLC26A4 genes have been recognized as the disease genes mutated in diastrophic dysplasia, congenital chloride diarrhea, and Pendred syndrome, respectively.',1 'Twenty-one patients received tacrolimus-mycophenolate mofetil maintenance immunosuppression, whereas the other patients received tacrolimus-sirolimus (SIR, n = 5) or SIR only (n = 5).',1 'The essential features of aplastic anemia by chloramphenicol are outlined.',1 'His eosinophilia progressed nonetheless, but responded partially to imatinib.',1 'HIT may affect 1-3% of patients who receive unfractionated heparin, and this case raises the possibility that heparin may contribute to, or cause, some episodes of skin necrosis attributed to warfarin.',1 'In a further nine patients tulobuterol 200 micrograms and 400 micrograms aerosol inhibited exercise-induced asthma following 6-8 min treadmill exercise and the effect was comparable to 200 micrograms salbutamol aerosol.',1 'Both drugs were well tolerated, with treatment-related adverse events, of which headache and gastrointestinal disturbances were the most common, occurring in 12% and 6% of patients in the trovafloxacin 200 mg and 100 mg groups, respectively, and in 9% of amoxicillin-treated patients.',1 'Prostate cancer: a newly discovered route for testosterone to reach the prostate : Treatment by super-selective intraprostatic androgen deprivation.',1 'However, caspase activity was not essential for docetaxel-induced cytotoxicity since cell death associated with lysosomal membrane permeabilization still occurred in the presence of caspase inhibitors.',1 'In this distinct clinical syndrome, aspirin and most other nonsteroidal anti-inflammatory drugs that inhibit cyclooxygenase precipitate rhinitis and asthma attacks.',1 'BACKGROUND : Recent studies have shown that tamoxifen, which belongs to a group called selective estrogen receptor modulators (SERM), may exert protective effects against cardiovascular diseases and stroke in postmenopausal women.',1 'Atorvastatin restores endothelium-dependent vasodilation in normocholesterolemic cigarette smokers independent of changes in lipids.',1 'The mixed agonist-antagonist analgesics buprenorphine, butorphanol, nalbuphine, pentazocine and picenadol were compared to the prototype mu and kappa agonists morphine and Mr 2033, respectively, in the following tests in rhesus monkeys: overt behavioral effects upon acute administration in drug-naive animals; discriminative stimulus properties in monkeys trained to respond to either etorphine or ethylketazocine; self-administration of the test agent relative to codeine; single dose suppression and precipitation in withdrawn and non-withdrawn morphine-dependent monkeys, respectively; and primary addiction studies in drug-naive animals.',1 'Essential fatty acids (EFAs) and their metabolites: eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), gamma-linolenic acid (GLA), dihomo-gamma-linolenic acid (DGLA), and arachidonic acid (AA) and their products: prostaglandin E1, prostacyclin, lipoxins, resolvins, and protectins suppress inflammation, augment healing, and are of benefit in the prevention and management of these conditions.',1 'Altered hypothalamic-pituitary function in the adult female rat with streptozotocin-induced diabetes.',1 '[Oxcarbazepine Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome mimicking septic shock].',1 'Recently, we have described a notorious anticonvulsant effect of thalidomide on pentylenetetrazole-induced seizures.',1 'Therefore, the acute effects of an intravenous (i.v.) infusion of isradipine (0.4 mg) vs. nifedipine (2.0 mg) on cardiac hemodynamics and systolic wall stress were investigated in a crossover study of 12 hypertensive patients.',1 'The new calcium antagonist anipamil (1,7-bis-(3-methoxyphenyl)-3-methylaza-7-cyano-nonadecane) exhibited a pronounced protective effect against isoprenaline-induced myocardial necrosis in rats.',1 'The broken balance in aspirin hypersensitivity.',1 'We report a case of glioblastoma multiforme and partial epilepsy treated with levetiracetam with subsequent development of thrombocytopenia.',1 'OBJECTIVE : To evaluate the role of adrenal and thyroid hormones in the prediction of death in a population of critically ill puppies with parvoviral diarrhea by measuring serial daily serum concentrations of cortisol and thyroxine.',1 'Medrysone hypersensitivity. Report of a case.',1 'Comparative studies suggest that cyclosporine A-based immunosuppression may provide improved responses to antiviral therapy and reduced incidence of PTDM compared with tacrolimus-based immunosuppression.',1 '[Hepatitis due to nitrofurantoin (authors transl)].',1 'However, within and between treatments, there were trends favoring fluvoxamine on symptoms common in dementia (confusion, irritability, anxiety, fear-panic, mood level and restlessness).',1 'Erlotinib-induced rash appears to be predictive of outcome.',1 'Hemorrhagic cystitis and ureteritis, and interstitial nephritis developed in a patient receiving penicillin G and streptomycin as therapy for bacterial endocarditis.',1 'To determine whether factor V Leiden is associated with thrombotic events in patients with heparin-induced thrombocytopenia (HIT), we evaluated 165 patients with serologically confirmed HIT for the presence of factor V Leiden and determined the incidence of venous or arterial thrombosis during the period of HIT.',1 'The results suggest a differential renal response to streptozotocin-diabetes according to the stage of renal growth and development, and it is proposed that the difference is related to the developmental emergence of aldose reductase.',1 'Compared with the control group (431.7 +/- 37.3 s), the latencies of onset of convulsions in the fentanyl groups were dose-dependently decreased (F50: 331.0 +/- 37.1 s; F100: 240.3 +/- 28.6 s, p < 0.001; F200: 188.7 +/- 19.4 s, p < 0.001), and the decreased latency was reversed by naloxone (F100+N: 412.9 +/- 34.1 s).',1 'The data show that aminophylline did not alter the ability of gabapentin to protect mice against seizures induced by electroconvulsive shock.',1 'Effect of iohexol on pulmonary arterial pressure at pulmonary angiography in patients with pulmonary hypertension.',1 'A 37-year-old woman with a neuroma (caused by surgical intervention for an endometrial sarcoma) producing neuropathic pain unresponsive to opiates was successfully treated with intravenous infusion of 1,500 phenytoin equivalent units fosphenytoin for 24 hours.',1 'MEASUREMENTS AND MAIN RESULTS : Compared with placebo, subjects receiving dolasetron mesylate reported a greater frequency of headache, light-headedness, dizziness, increased appetite, and nausea.',1 'The results confirm a suppression of inflammation by capsaicin and imply that the nociceptive and pro-inflammatory (neurogenic inflammation) activities of capsaicin-sensitive fibres are closely linked such that stimuli which cause pain will also induce neurogenic inflammation and vice versa.',1 'This was an unanticipated result because valproic acid has been associated with weight gain because of increased appetite.',1 '[Toxic methemoglobinemia caused by a gingival lotion containing benzocaine and resorcin].',1 'The relationship of these findings with the mechanism of histamine liberation in anaphylaxis is discussed.',1 'Effectiveness of bumetanide with low-dosage dopamine for diuresis.',1 'Acute interstitial pneumopathy associated with docetaxel hypersensitivity.',1 'In contrast, rates of rhabdomyolysis AERs (OR 2.67, 95% CI 2.11 to 3.39, p <0.001) and muscle-related AERs without rhabdomyolysis (OR 1.36, 95% CI 1.12 to 1.71, p = 0.002) were significantly higher for gemfibrozil compared with fenofibrate.',1 'We used four methods to determine the temperature for 50% change in activity or cell death (LT(50)) of leaves: (1) electrical conductivity (electrolyte leakage into a bathing solution), (2) photosynthetic fluorescent capacity (Fv/Fm), (3) percentage of palisade mesophyll cells stained by fluorescein diacetate vital stain, and (4) visual score of leaf color (Munsell color chart).',1 'No serious adverse events related to study medication occurred, although more donepezil (34.3%) than placebo (8.8%) subjects reported unusual/abnormal dreams (p = 0.010).',1 'PURPOSE : A case of acyclovir-induced acute renal failure in an obese patient is described.',1 'Fab fragments purified from the IgG of two quinidine-induced lupus patients and patients with isoniazid- and procainamide-induced lupus retained 39% +/- 8% of their original IgG reactivity compared to 34 +/- 28% of the original anti-tetanus toxoid activity of Fab fragments in two of the same sera and two normal sera.',1 'The endothelial damage markers of soluble thrombomodulin, soluble P-selectin (p < 0.05 vs. normal), plasminogen activator inhibitor-1 and tissue factor were elevated in heparin-induced thrombocytopenia and antiphospholipid antibody syndrome patients.',1 'Heparin was reported to have a beneficial impact on mortality, graft and wound healing, and pain control.',1 'Prolonged high-dose oral and intravaginal metronidazole therapy did not resolve the infection, but caused temporary peripheral neuropathy.',1 'Lepirudin (Refludan; Berlex, Wayne, NJ) and argatroban (Argatroban; GlaxoSmithKline, Research Triangle Park, NC) are given intravenously and are usually used in HIT and thrombosis associated with HIT.',1 'Testosterone-induced DNA synthesis in cultured rat ventral prostate. I. Effects of cyproterone acetate.',1 'Bradycardia and hypotension may be associated with the use of clonidine.',1 'Rhabdomyolysis connected with the use of bupropion.',1 'Diagnosis of MSF was made after the appearance of a maculo-papular skin rash, and treatment with oral doxycycline was started.',1 'Such extravasation of the fluorescein remained after the dye had faded from the venules and veins.',1 'However, sufentanil, an opioid analgesic, has not been evaluated as an agent for managing pain on injection of propofol.',1 'Of the patients prescribed H2-receptor antagonists or omeprazole, 45% (accounting for 51% of prescription items) had indications which included peptic ulcer or oesophagitis, 42% had gastritis or dyspepsia only (35% items), and in 13% no peptic indication was recorded.',1 'Effects of histamine H1-receptor blockade on respiratory and cardiac manifestation of systemic anaphylaxis.',1 'The repeated surveys and studies have noted that iron deficiency anemia, vitamin A deficiency, iodine deficiency are highly prevalent amongst the children in the country and the preventive interventions are reaching only small proportion of 10-50% of the targeted populations.',1 'The mean (+/- SD) duration of pain during the first week of treatment was 1.9 +/- 2.6 days in the omeprazole group, as compared with 3.6 +/- 3.0 days in the antibacterial-treatment group (P = 0.004).',1 'Hydrocortisone sodium succinate does not cross-react with aspirin in aspirin-sensitive patients with asthma.',1 'We speculate that these findings are due to a continuation of the fetal situation in which chronic hypoxia, mostly caused by pregnancy-induced hypertension, possibly causes a prostacyclin-induced vasodilatation.',1 'OBJECTIVE : Our goal was to report a new case of gatifloxacin-related hyperglycemia in a nondiabetic patient with acute renal dysfunction.',1 'Co-administration of nitric oxide (NO) donors prevents haloperidol-induced orofacial dyskinesia, oxidative damage and change in striatal dopamine levels.',1 'It is concluded that, in Mongolian gerbils, H. pylori infection delayed the healing of preexisting gastric ulcers and resulted in the relapse of healed ulcers, yet indomethacin had little or no effect on ulcer healing or relapse.',1 'A chitosan-egg phosphatidylcholine (chitosan-ePC) implant system containing PLA-b-PEG/PLA nanoparticles has been developed for the delivery of paclitaxel to treat ovarian cancer.',1 'The effects of betaxolol, a cardioselective beta-adrenoceptor antagonist, on ischemic myocardial acidosis were studied in dog hearts, in which the left anterior descending coronary artery was partially occluded for 90 min, and were compared with those of atenolol and propranolol.',1 'In rats with deoxycorticosterone acetate (DOCA) salt hypertension, induction of diabetes with streptozotocin did not aggravate the elevation in blood pressure, but pressor and sympathetic nerve responses to electrical stimulation of the ventromedial hypothalamus were enhanced.',1 'RESULTS : Inactivating GR within dopaminoceptive neurons markedly reduces cocaine-induced conditioned place preference and the expression of locomotor sensitization.',1 'CONCLUSIONS : Oral budesonide appears to be of minimal, if any, benefit and it is associated with a significant worsening of osteoporosis in patients with PSC.',1 'These data do not support the usefulness of the urinary cortisol-creatinine index as a marker of nocturnal hypoglycemia in diabetes.',1 'Postpartum myocardial infarction in a patient receiving bromocriptine.',1 'The aim of the present study was to assess the relative diagnostic and prognostic accuracies of high-dose dipyridamole echocardiography (two-dimensional echocardiographic monitoring during dipyridamole infusion up to 0.84 mg/kg over 10 hours) versus maximal symptom-limited bicycle exercise ECG test in patients with angina.',1 'Randomized study of propofol effect on electrophysiological properties of the atrioventricular node in patients with nodal reentrant tachycardia.',1 'Aspirin sensitivity and desensitization for asthma and sinusitis.',1 'Pancreatitis caused by methyldopa.',1 'No correlation was found between beta-tubulin III mRNA expression and docetaxel sensitivity in malignant effusions of gastric cancer patient.',1 'IMPLICATIONS: Sufentanil is added to epidural infusions of ropivacaine 0.2% wt/vol to improve the effectiveness of postoperative pain management.',1 'In conclusion, under our experimental conditions, diabetes affects selectively the coronary vasodilation to iloprost.',1 'Usefulness of moexipril and hydrochlorothiazide in moderately severe essential hypertension.',1 'Effects of carvedilol on cardiac function and cardiac adrenergic neuronal damage in rats with dilated cardiomyopathy.',1 'RESULTS : In eight normal subjects intravenous quinidine (8 mg/kg body weight infused for 27 min) decreased mean arterial pressure from 87 +/- 3 (mean +/- SE) to 83 +/- 3 mm Hg, central venous pressure from 6.3 +/- 0.6 to 5.0 +/- 0.7 mm Hg and forearm vascular resistance from 32.2 +/- 5.5 to 25.3 +/- 4.7 U (all p < 0.05).',1 'A controlled comparison of amcinonide cream 0.1 percent and halcinonide cream 0.1 percent in the treatment of eczematous dermatitis.',1 'Cisplatin may be a valid alternative approach in ovarian carcinoma with carboplatin hypersensitivity. Report of three cases.',1 'ATR prevented pilocarpine-induced diarrhea most strongly in diarrheal models.',1 '(3) Corticosterone had a biphasic, dose-dependent effect; the most significant attenuation of the hypersensitivity to morphine-induced antinociception in adrenalectomized rats was achieved after 0.01 mg and after 10 mg (per kg b.w.).',1 'In a double-blind, parallel-group, multicenter, comparative trial in 120 evaluable patients with chronic, localized atopic dermatitis or lichen simplex chronicus, the success rate (described as "healed" and "marked improvement") was 91.5% in patients treated with halobetasol propionate ointment and 83.6% in those in the diflucortolone valerate treatment group.',1 'CONCLUSION : Switching cyclophosphamide to azathioprine after induction of remission in patients with PR3-ANCA-associated vasculitis who are still ANCA-positive at the time of treatment switch is associated with a high risk of relapse.',1 'Etiologies included hypoxic-ischemic encephalopathy; haloperidol treatment with and without neuroleptic malignant syndrome; toxicity of cytosine arabinoside, cyclophosphamide, amphotericin B, and methotrexate; St. Louis encephalitis and other encephalitides; and a pineal tumor with hydrocephalus.',1 'PATIENTS AND METHODS : Chemonaive NSCLC patients with BM ineligible for (radio)surgery, performance status (PS) of 0 to 2, were eligible for up to six cycles of cisplatin 75 mg/m(2) and pemetrexed 500 mg/m(2) every 3 weeks.',1 'To compare the sensitivity of dipyridamole, dobutamine and pacing stress echocardiography for the detection of myocardial ischemia we produced a physiologically significant stenosis in the left circumflex artery of 14 open-chest dogs (range: 50 to 89% reduction in luminal diameter).',1 'Therefore, all the data in this study suggest that NGF accelerates the early necrosis of glucose-starved cell death probably through the alterations of intracellular calcium ions and protein syntheses.',1 'The cisplatin 30 mg/m(2) was also administered along with a program of forced diuresis that included at least 2000 ml of fluids after the paclitaxel infusion over 30 min on Days 1 and 8.',1 'Acute myocardial ischemia after administration of ondansetron hydrochloride.',1 'Oral exposure to low-dose bisphenol A aggravates testosterone-induced benign hyperplasia prostate in rats.',1 'METHODS : As part of a prostate cancer screening program, we prospectively evaluated 354 men (mean age 60.7 years) by physical examination for the presence of a varicocele, testicular size, and consistency, and measured the serum testosterone level.',1 'Comparing the equitoxic doses, which were close to therapeutic dosages, we found a greater inhibition of delayed-type hypersensitivity in the second-generation platinum complexes than in cisplatin.',1 'In contrast to controls, ascending infection resulting in endometritis was found in animals receiving doses of greater than or equal to 1.0 microgram of estradiol per day.',1 '[A case of advanced gastric cancer with pulmonary carcinomatous lymphangitis responding remarkably to combination chemotherapy of docetaxel, CDDP and S-1].',1 'Effectiveness of amiodarone for conversion of atrial fibrillation to sinus rhythm: a meta-analysis.',1 'Morphine markedly sensitized mice to oral infection, as assessed by survival, mean survival time, and colony culture.',1 'Postmortem neuropathologic examination revealed severe cerebellar atrophy of the internal granule and Purkinje cell layers with attendant Bergmann gliosis presumably resulting from chronic lithium use and toxicity.',1 'CASE : Six days after the patient began sulfadiazine treatment for toxoplasmosis, he developed low back pain radiating into the abdomen and kidney failure with obstructive uropathy, followed by anuria.',1 'Based on results from a meta-analysis, rizatriptan 10 mg (41%) and almotriptan (35%) seem superior to telcagepant (26%) for pain free at 2 hours whereas rizatriptan 10 mg (25%) showed no difference from telcagepant 300 mg (19 %) for sustained pain free (2-24 hours).',1 'Combination therapy of levosulpiride and lamotrigine associated with tardive dyskinesia.',1 'Calcinosis, wherever it appears, is no more than overloading of the conjunctive tissue with calcium.',1 'Case report. Immunological studies in a case of hepatitis following methyldopa administration.',1 'GH secretion has been evaluated in all patients by means of TRH, bromocriptine and insulin hypoglycemia tests, too.',1 'RESULTS : Fentanyl suppressed emergence cough in a dose-related manner (P = 0.002), and the ED(50) and ED(90) were 1.1 mcg/kg and 2.1 mcg/kg, respectively.',1 '11q23 aberration is an additional chromosomal change in de novo acute leukemia after treatment with etoposide and mitoxantrone.',1 'The ABCD (Appropriate Blood Pressure Control in Diabetes) and ABCD-2V (Part 2 with Valsartan) are prospective, randomised clinical trials which will provide important data on the impact of intensive vs. moderate blood pressure (BP) control on microvascular and macrovascular complications in normotensive and hypertensive patients with type 2 diabetes mellitus (DM).',1 'MAIN OUTCOME MEASURES : Vertigo frequency, hearing status, personal disability ratings, tinnitus level, and caloric responses before and after gentamicin therapy were measured.',1 'A case of a previously unrecognized form of hypersensitivity to procarbazine characterized by a nonpigmented fixed drug eruption is reported.',1 'PURPOSE : To study if dopamine in dopaminergic doses (1.5 and 4.0 micrograms/kg/min) had some effect on the pulmonary vasoconstriction mechanism, and if in those doses the drug had some action on systemic and pulmonary hemodynamic variables, as well as in the pulmonary gas exchange.',1 '[Acute pancreatitis induced by drugs derived from 5-aminosalicylic acid: case report and review of the literature].',1 'Two patients, who had completed fludarabine treatment 3 and 18 months previously, presented with visual loss that had been preceded by a recent history of cutaneous zoster.',1 'Potentially serious side effects of intermittent treatment or repeated therapy with rifampicin. Danger of acute renal failure.',1 'Thyroid function test abnormalities in patients with metastatic renal cell carcinoma treated with sorafenib.',1 'Both phenobarbitone and phenytoin sodium also caused an increase in the incorporation of 3H-leucine at concentrations of 50 and 20 mug per ml, respectively, suggesting the possibility that a stimulation of protein synthesis within erythropoietic cells may play an important role in the development of anticonvulsant-induced macrocytosis.',1 'After chemotherapy with irinotecan and carboplatin, abdominal pain and serum amylase levels resolved dramatically.',1 'We describe the case of a patient with PD who developed severe akathisia, a common complication with classical antipsychotics, with quetiapine.',1 'Delayed cerebral vasospasm is not reversible by aminophylline, nifedipine, or papaverine in a "two-hemorrhage" canine model.',1 'Additionally, there is evidence that low testosterone levels may predict the development of type 2 diabetes.',1 'Salbutamol-induced narrow QRS tachycardia: what is the mechanism?',1 '[Urticaria appearing following penicillin treatment limited to areas affected with pityriasis versicolor].',1 'Weekly low-dose paclitaxel as maintenance treatment in patients with advanced ovarian cancer who had microscopic residual disease at second-look surgery after 6 cycles of paclitaxel/platinum-based chemotherapy: results of an open noncomparative phase 2 multicenter Italian study (After-6 Protocol 2).',1 'PURPOSE : Epidural morphine has been associated with a significant incidence of postoperative nausea and vomiting (PONV).',1 'Since arsenic can prolong the QT interval and lead to torsade de pointes, a life-threatening ventricular arrhythmia, this retrospective analysis was conducted to determine the degree of QT prolongation in patients treated with arsenic trioxide.',1 'Recurrent visual field defect and ischemic optic neuropathy associated with tadalafil rechallenge.',1 'Islets isolated from syngeneic donors were grafted under the kidney capsule of Wistar-Furth rats (n = 7) after 3 wk of streptozotocin induced diabetes.',1 'Low renin, "normal" aldosterone and hypertension: circadian rhythm of renin, aldosterone, cortisol and growth hormone.',1 'At a concentration of 20 mmol/L, adenosine converted ventricular fibrillation into ventricular tachycardia with intermittent periods of asystole.',1 'The inflammatory infiltrate was examined immunocytochemically in lesional skin specimens from the patient, in the patients patch test response to carbamazepine, and in lesional skin specimens from five other patients with drug-induced erythema multiforme.',1 'All groups receiving radiation and chemotherapy (particularly carboplatin and etoposide) had an increased incidence of hind limb paralysis, resembling experimental allergic neuritis (P = 0.053).',1 '[Convulsions and shock during antimalarial chemoprophylaxis with mefloquine].',1 'Grade 3 non-dose limiting mucositis and dermatitis occurred at all paclitaxel dose levels.',1 'After induction of diabetes with streptozotocin, female Wistar rats were divided into 2 groups.',1 'The current study aims to investigate the anti-tremogenic and neuroprotective effects of memantine (NMDA receptor antagonist) on the harmaline model of transient action tremor.',1 'The micronutrient control program aims to prevent and control iodine deficiency disorders, vitamin A deficiencies, and iron deficiency anemia.',1 'The rate of flecainide elimination from plasma is somewhat slower in patients with moderate renal failure and in patients with CHF than that for healthy persons, and is markedly slower in some patients with end-stage renal disease.',1 'Adenosine has been implicated in the pathogenesis of cardiac pain through activation of cardiac sympathetic afferents.',1 'Antidepressant activity and mania associated with risperidone treatment of schizoaffective disorder.',1 'Furthermore, morphine-induced analgesia in a hot-plate test showed a leftward shift in the morphine dose-response curve after naloxone treatment.',1 'The disposition of chloroquine and its main metabolite desethylchloroquine in volunteers with and without chloroquine-induced pruritus: evidence for decreased chloroquine metabolism in volunteers with pruritus.',1 'Heparin induced thrombocytopenia-type 2.',1 'The present results, which need to be confirmed (the present analysis has been done in spring 95) suggest that:-the use of non radio-mimetic agents does not protect against leukemic transformation, which may be a consequence of the disease; rather than of the treatment,-maintenance therapy after initial use of 32P increases the risk of both leukemia and carcinoma,-and hydroxyurea does not delay the risk of developing myelo-fibrosis, in comparison with 32P alone.',1 'The protective effect of heparin in experimental bladder infection.',1 '[Effects of various antihypertensive drugs with and without hydrochlorothiazide on the diuresis test].',1 'Nifedipine and pentoxifylline had to be stopped in two evaluable patients due to hypotension, and three additional inevaluable patients withdrew from the study due to nifedipine-pentoxifylline toxicity before receiving their chemotherapy.',1 'Patterns of dosage changes with transdermal buprenorphine and transdermal fentanyl for the treatment of noncancer and cancer pain: a retrospective data analysis in Germany.',1 'Furthermore, heparin involvement in the RT step can eliminate completely the false-positive PERT signals which are exhibited by cellular polymerases such as DNA-dependent DNA polymerase alpha, gamma released by cell death.',1 'A suspension formulation containing sarafloxacin HCl, triamcinolone acetonide, and clotrimazole was developed for the treatment of otitis externa in dogs.',1 'The effect of lansoprazole versus an H2-receptor antagonist on the contraction of ulcer echoes (study II) was also investigated.',1 'METHODS : Neutrophils of healthy subjects and ischemic stroke patients were treated with tumor necrosis factor alpha (TNF alpha), in the presence or absence of different concentrations of isoflavoid (WZ1, WZ2) and estradiol (WZ3, WZ4).',1 'The most common adverse event, dry mouth, occurred in 20 patients in the propiverine group and in 19 patients in the tolterodine group.',1 'Hence, although in isolated human coronary arteries high concentrations of calcium antagonists were shown to induce a considerably greater vasodilation than nitrocompounds, the early drop in blood pressure prohibits a higher dosage of calcium antagonists in vivo.',1 'Further studies are needed to elucidate the role of danazol itself or of the danazol-hereditary angioneurotic edema interaction in the pathogenesis of these abnormalities.',1 'Neutropenia is the major dose-limiting toxicity of docetaxel, but other haematological effects are rare.',1 'Lymphopenia was the most commonly reported AE in patients treated with cladribine tablets and was anticipated based on the mechanism of action.',1 'TCDD (dioxin) induces a rapid inflammatory response from 3T3-L1 adipocytes as judged by prominent induction of the mRNA expression of prostaglandin-endperoxide synthase 2 (Cox-2) along with other inflammation markers within 1 h. This action of TCDD is clearly antagonized by cell pretreatment with AACOCF3 (an inhibitor of cPLA2), nifedipine (a Ca(2+) channel blocker), or 3-methyl-4-nitroflavone (MNF), an antagonist of the Ah receptor (AhR), suggesting the possible involvement of the nongenomic pathway of action of TCDD as shown previously in MCF10A cells [Dong, B., and Matsumura, F. (2008) Mol.',1 'The effect of diabetes induced by treatment of rats with streptozotocin on metabolism of circulating 5-hydroxytryptamine (5HT) was investigated using an in situ lung perfusion preparation.',1 'All patients were given premedication (prednisone, clemastin, cimetidine) to prevent hypersensitivity reactions.',1 'Role of peroxisome proliferator-activated receptor-alpha (PPARalpha) in bezafibrate-induced hepatocarcinogenesis and cholestasis.',1 'Treatment with danazol for refractory thrombocytopenia in rheumatoid arthritis.',1 'In the NHL-BFM 90 protocol, all AA and BB courses include high-dose methotrexate therapy, which consists of aggressive alkalinized hydration, methotrexate 5 g/m(2) given as an i.v. infusion over 24 hours, and leucovorin rescue.',1 'Accordingly, in the present study we investigated the effects of bisoprolol on ventricular I(Na) in diastolic heart failure (DHF) and normal rats.',1 'PURPOSE : This study was undertaken to select the optimal combination schedule of erlotinib and pemetrexed for the treatment of relapsed non-small cell lung cancer (NSCLC) using a panel of human NSCLC lines.',1 'Pathogenic mechanism, prophylaxis, and therapy of symptomatic acidosis induced by acetazolamide.',1 'Pretreatment with TKI (41 micromol kg(-1), i.p.) reduced the capsaicin-induced neurogenic inflammation in the mouse ear by 54%.',1 'Therapy of prednisone plus cyclophosphamide was effective for lupus cystitis.',1 'Intra-VTA microinjection of anti-NT-3 resulted in enhanced sensitization to repeated cocaine injections in that the cocaine-induced behavioral response in the anti-NT-3 group was significantly greater than the vehicle group following the second and third daily injections of cocaine.',1 'The effects of caffeine, halothane, succinylcholine, phenylephrine and isoproterenol on force of contraction were studied in electrically driven (0.2 Hz) trabeculae isolated from the right ventricles of the hearts of malignant hyperthermia susceptible (MHS) and healthy control (nMHS) swine.',1 'We report the successful treatment of heparin-induced thrombocytopenia and subsequent hemorrhagic complications postoperatively in a 2-year-old child with Danaparoid (orgaran).',1 'From baseline to month 12, the mean plaque volume increased by 7.7 mm(3) for eprosartan-treated patients and by 34.4 mm(3) for diltiazem-treated patients, but the eprosartan-related trend for reduced myointimal hyperplasia was not statistically significant.',1 'Recent animal studies suggest that heparin might also inhibit cholinergic neurotransmission in asthma by restoring inhibitory M2 receptor function.',1 'The utility of using beta blocking drugs, specifically Pindolol, as a prophylaxis for arrhythmia during cardiac microcatheterism according to Grandjeans technique has been observed.',1 'Furthermore, the number of cocaine/crack cocaine death mentions correlated positively with the number of crack offenders (p < 0.001) and seizures (p < 0.001), but correlated negatively with both crack purity ( p < 0.001) and price (p < 0.05).',1 'Is the intake and stopping time of tamsulosin important to the occurrence of IFIS?',1 'RESULTS : Propofol suppressed HIF-1alpha protein accumulation induced by LPS, but not by hypoxia in the THP-1 cells in a dose-dependent manner by inhibiting the neo-synthesis of HIF-1alpha protein.',1 'This method allows for a rapid clearance of morphine and its metabolites are rapidly cleared, except in patients with renal failure.',1 'Doxorubicin-induced cell death did not appear to be mediated by p53 in either cell line.',1 'The condition of the hypophyseal-thyroid system in patients with angina of effort and in those with myocardial infarction in the acute stage was studied by determining the content in the blood of the thyrotropic hormone (TTH), thyroxin (T4), and triiodthyronine and 2-hour iodine uptake by the thyroid.',1 'Lithium carbonate for recurrent fever and neutropenia.',1 'This study evaluated the effects of sildenafil on men with erectile dysfunction and Type II diabetes and compared the results with glycated haemoglobin concentrations and chronic diabetic complications.',1 'Of the patients discontinuing therapy for adverse events, 5 of the sertraline-treated patients did so because of sexual dysfunction reported as an adverse event, whereas only 1 of the nefazodone-treated patients discontinued therapy secondary to sexual dysfunction.',1 'Culture fluids were screened by ELISA for antibody reacting with Hb G-Philadelphia but not Hb A. One such culture was cloned by limiting dilution, expanded and injected into pristane-primed, cyclophosphamide-suppressed BALB/c mice for ascites production.',1 'CONCLUSION : modafinil improved alertness and cognitive skills in patients receiving cancer pain treatment by enhancing vigilance and cognitive performance.',1 'Expressed as improvement > or =10 points from baseline (PEFG/gemcitabine), these were: emotional function (43/18%), fatigue (41/17%), QOL (55/29%), pain (64/41%), and flatulence (50/26%).',1 'METHODS : To assess whether the erythrocyte accumulation of 6TGN is a clinically applicable index for monitoring azathioprine treatment, erythrocyte accumulation of 6TGN was measured in patients with rheumatoid arthritis (n = 12), systemic lupus erythematosus (n = 7), polyarteritis nodosa (n = 2), myositis (n = 1), or leukocytoclastic vasculitis (n = 1).',1 'At early time points, there appeared to be a reduction of the primary composite end point of death, myocardial infarction, or refractory ischemia among women treated with tirofiban plus heparin (RR, 0.78 and 0.67) compared with women treated with heparin alone.',1 'Article on mitoxantrone-induced extravasation raised useful questions.',1 'Effects of naloxone on post-operative pain and steroid-induced analgesia.',1 'A novel anti-inflammatory role for simvastatin in inflammatory arthritis.',1 'The purpose of this study was to investigate whether, to what extent, and through which mechanisms intravenous heparin, administered before and after streptokinase, affects the plasma levels of D-dimer and fibrinogen in myocardial infarction.',1 'IMPLICATIONS: We compared the efficacy of ondansetron, lidocaine, tramadol, and fentanyl in minimizing the pain on injection of rocuronium in 250 patients.',1 'A 16 year old girl presented massive chemical cystitis and severe bleedings of the bladder mucosa after systemic long-term low-dose chemotherapy with cyclophosphamide.',1 'But early death rate, the average survival times and the rate of abscess formation were significantly lower in the heparin treated group.',1 'The magnitude of this early-phase hypotension was attenuated in rats pretreated with intravenous (i.v.) mu-subtype-selective doses of either naloxone or methylnaloxone but not central doses of the selective mu-opioid antagonist beta-funaltrexamine.',1 'Nifedipine with and without propranolol in the treatment of myocardial ischemia: effect on ventricular arrhythmias and recovery of regional wall function.',1 'CONCLUSION : Metered dose inhaler with spacer and dry powder inhaler have equal efficacy in delivering salbutamol in therapy of mild to moderate acute exacerbations of bronchial asthma in children between 5-15 years of age.',1 'PURPOSE : To measure the effect of PIXY321 (granulocyte-macrophage colony-stimulating factor/interleukin-3 S. cerevisiae fusion protein) on the incidence, duration, and complications of neutropenia and thrombocytopenia after moderate-dose fluorouracil 600 mg/m(2), doxorubicin 60 mg/m(2), and cyclophosphamide 750 mg/m(2) (FAC) chemotherapy in patients with stage II and III breast cancer.',1 'Inhibition of surgically induced miosis and prevention of postoperative macular edema with nepafenac.',1 'All patients had mild to moderate hypertension and received triple immunosuppressive therapy with CsA, azathioprine, and prednisolone.',1 'Potentiation of cisplatin antitumour activity by Ethyldeshydroxy-Sparsomycin in L1210 leukemia.',1 'Bromocriptine induces parapoptosis as the main type of cell death responsible for experimental pituitary tumor shrinkage.',1 'Improvement of HbA1c without increased hypoglycemia in adolescents and young adults with type 1 diabetes mellitus treated with recombinant human insulin-like growth factor-I and insulin. rhIGF-I in IDDM Study Group.',1 'A case is presented of a young, chronic tetraplegic patient who, shortly after achieving therapeutic levels of imipramine, a tricyclic antidepressant (TCA) developed a life-threatening ventricular arrhythmia.',1 'Risperidone in the treatment of chronic schizophrenic patients: an international double-blind parallel-group study versus haloperidol. The International Risperidone Research Group.',1 'This suggests that levetiracetam may have potential anxiolytic effects and may provide therapeutic benefits to individual with anxiety spectrum disorders.',1 'Monitoring of clozapine-induced myocarditis.',1 'Biogenic amines such as norepinephrine, dopamine, and serotonin play a well-described role in the treatment of mood disorders and some types of pain.',1 'To further examine the role that substance P plays in initiating the observed massive postmortem bronchoconstriction in guinea pig lungs and to explore the role of neural reflex in this airway spasm, six groups of animals were employed: control (n = 6), morphine (n = 6), substance P (n = 5), chronic capsaicin pretreatment + substance P (n = 5), tetrodotoxin (TTX) + acute capsaicin (n = 4), and chlorisondamine + acute capsaicin (n = 5).',1 'Topical retinoic acid has proved to be of variable benefit in a number of dry eye disorders of disparate aetiology, in which squamous metaplasia with keratinization of ocular epithelium is present.',1 'For example, the sensitivity of capsaicin-induced cough responses following upper respiratory tract infection and in airway inflammatory diseases such as asthma and COPD is increased relative to that of control responses.',1 'The incidence of heparin-induced thrombocytopenia in human immunodeficiency virus (HIV)-infected inpatients was compared with that in a control group that was not known to be infected with HIV in a retrospective cohort study.',1 'Cromolyn sodium aerosols prevented 48/80 induced asthma but did not influence histamine induced broncho-constriction.',1 'Intense blood pressure control with felodipine, enalapril, and hydrochlorothiazide reduced overall cardiovascular events and mortality but not myocardial infarction and strokes in the Hypertension Optimal Treatment trial.',1 'Ciliated cyst of the vulva: oestrogen and progesterone receptors.',1 'Post hoc analysis showed a significant benefit of rizatriptan versus placebo in the percentage of patients who had pain relief when their migraine attacks were treated on weekends (65% versus 36%, P=.046) compared with weekdays (66% versus 61%, P=.365), and the weekend placebo response rate was similar to that seen in adults.',1 'RESULTS : Subjective measures of effects of cocaine, including self-report ratings of intensity of the drug effect, scores on the morphine-benzedrine scale of the Addiction Research Center Inventory, and several items on visual analogue scales, correlated negatively with VBR.',1 'Behavioral sensitization to cocaine in rats: evidence for temporal differences in dopamine D3 and D2 receptor sensitivity.',1 'METHODS : Twelve isoflurane-anesthetized Sprague-Dawley rats underwent moderate (2.0 atm) fluid percussion traumatic brain injury followed by either normotension or hemorrhagic hypotension.',1 'OBJECTIVE : To compare the analgesic efficacy of valdecoxib with placebo and naproxen sodium for relieving menstrual cramping and pain due to primary dysmenorrhea.',1 'Colchicine myopathy may occur in patients with gout who take customary doses of the drug but who have elevated plasma drug levels because of altered renal function.',1 'Chronic (14 days) but not acute treatment with antidepressants (amitriptyline, imipramine, desipramine, clomipramine, mianserin, danitracen, iprindole) potentiated the aggressive behaviour induced by apomorphine (APO) in rats.',1 'RESULTS : The overall incidence of CMV infection was 34% with no difference in incidence between the tacrolimus and cyclosporine-ME treatment arms.',1 'Dermatomyositis-like lesions seem to be a not infrequent and characteristic adverse reaction to hydroxyurea.',1 'Antibodies to heparin have cross-reactivity with enoxaparin; therefore, dermal necrosis secondary to enoxaparin may occur by a similar mechanism.',1 '[Open trial of carbamazepine in the prevention of recurrence of bipolar disorder in adolescents].',1 'Sympathetic blockade in treatment of hypertension. Clinical trial of bretylium tosylate.',1 'Rapidly-adapting receptor activity and intratracheal pressure in guinea pigs. II. Action of aspirin and salicylic acid in antagonizing mediators of allergic asthma.',1 'Prolonged respiratory depression caused by sublingual buprenorphine.',1 'Propranolol infusion (3 mg/kg) induced temporary heart failure for 4 to 6 hours with significantly decreased cardiac output and blood pressure.',1 'After the administration of histamine (1-100 micrograms) or a partially purified preparation of slow-reacting substance of anaphylaxis (5-100 U) to the sensitized heart there was no detectable release of thromboxane B2 into the coronary effluent.',1 'Cytosolic retinoic acid receptor in carcinoma, chronic pancreatitis, and normal pancreatic tissue were examined using sucrose density gradient centrifugation, isoelectric focussing on agarose gel and saturation analysis.',1 '(3) In rats with streptozotocin-induced diabetes, atrial natriuretic peptide does not play a role in their hyperfiltration.',1 'CONCLUSION : Determination of selected cytochrome P450 enzyme genotypes may be valuable for predicting the risk of premature ovarian failure in lupus nephritis patients treated with cyclophosphamide.',1 'Effects of fenofibrate on high-fat diet-induced body weight gain and adiposity in female C57BL/6J mice.',1 'The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) assay revealed that pretreatment of PC12 cells with pramipexole (1-100 microM) resulted in significant protection against H2O2-induced cell death in a concentration-dependent manner.',1 'With the exception of tumor hemorrhage-type events with gefitinib, the adverse event profiles were generally consistent with those previously observed.',1 'It was hypothesized that regular carrot juice intake would be associated with reductions in oxidative stress (8-iso-PGF2α) and inflammation (thromboxane B2, prostaglandin E2 metabolites, and hsC-reactive protein).',1 'CONCLUSIONS : Thus, a risk of permanent sterility is associated with the use of the CYADIC and CYVADIC regimens in young men, especially when the cumulative dose of cyclophosphamide is greater than 7.5 mg/m2.',1 'This fusion protein is targeted by all-trans retinoic acid (ATRA) and arsenic trioxide (As2O3), presently used in APL therapy.',1 'The (at least partial) overlap among the biochemical and morphological responses triggered by rapamycin considerably complicates the study of cell death-associated variables.',1 'Today ergotism is becoming more and more important as a complication in the treatment of migraine headache or thrombosis prophylaxis with DHE heparin.',1 'Gabapentin for overactive bladder and nocturia after anticholinergic failure.',1 'Nedocromil sodium (NS), a new pyranoquinoline dicarboxylic acid derivative, reported to be effective against both mucosal and connective tissue-type mast cells, was studied in ragweed-allergic rhinitis (RAR).',1 'We measured serum concentrations of thyroxine (T4), triiodothyronine (T3), reverse T3, free T4, thyroid-stimulating hormone, and cortisol in 62 victims of sudden infant death syndrome (SIDS) in 30 infants who died of known causes and in 15 living controls.',1 'Hypothalamic corticotrophin-releasing factor and norepinephrine mediate sympathetic and cardiovascular responses to acute intracarotid injection of tumour necrosis factor-alpha in the rat.',1 'We conclude that alternate day steroid therapy is indicated in adult renal transplant recipients to treat steroid-induced diabetes, hypertension and minor prednisone side effects, but is not useful for obesity.',1 'RESEARCH DESIGN AND METHODS : We placed Ldlr(-/-) and heterozygous LDL receptor knockout (Ldlr(+/-)) mice on a high-cholesterol (0.15%) diet, induced diabetes with streptozotocin (STZ), and assessed reasons for differences in plasma cholesterol.',1 'After 4 weeks treatment, nifedipine (60 mg), improved time to onset of 0.1 mV ST-segment depression from 536 s by 72 +/- 117s, time to onset of pain from 619 s by 56 +/- 120 s, and total exercise time from 685 s by 40 +/- 88 s. Atenolol 100 mg, had a comparable effect, time to onset of 0.1 mV ST-segment depression improved from 496 s by 53 +/- 129 s, time to onset of pain from 572 s by 57 +/- 118 s, and total exercise time from 653 s by 33 +/- 99 s. Between group analysis revealed no statistically significant differences for these exercise parameters.',1 'Efavirenz-associated QT prolongation and Torsade de Pointes arrhythmia.',1 'This study was undertaken to determine the effect of lidocaine pretreatment on reduction of succinylcholine-induced myalgia in patients undergoing general anesthesia for gynecological surgery.',1 '[Problems caused by spinal sufentanil analgesia at the end of labor].',1 'We conclude that metronidazole can be associated with a dose- and serum concentration-related mental confusion state, and that this side effect appears completely reversible upon discontinuing the drug.',1 'CONCLUSION : Oral contraceptives containing EE/desogestrel and EE/levonorgestrel were both effective in treating acne.',1 'OBJECTIVE : The purpose of this study was to evaluate the changes in lower abdominal pain and back pain among women with menorrhagia treated by hysterectomy or levonorgestrel-releasing intrauterine system (LNG-IUS).',1 'Pancytopenia and severe cytopenia induced by low-dose methotrexate. Eight case-reports and a review of one hundred cases from the literature (with twenty-four deaths)',1 'At doses of cocaine and amphetamine that caused seizures and death, nimodipine, nitrendipine and diltiazem did not offer any protection; rather, they potentiated the toxicities produced by these psychomotor stimulants.',1 'Development of the paediatric pain profile: role of video analysis and saliva cortisol in validating a tool to assess pain in children with severe neurological disability.',1 'Thus, the production of a tumoral circulating factor implicated in the pathogenesis of humoral malignant hypercalcemia may be influenced in a positive way by an increase in extracellular calcium concentration.',1 'Metoclopramide enhances labetalol-induced antihypertensive effect during handgrip in hypertensive patients.',1 'Phase I dose-escalating trials of didanosine revealed dose-limiting toxicities, including pancreatitis, and established a total daily dose of 12.5 mg/kg/day as the maximum tolerated dose.',1 'Treatment options are (a) a new extended-release form of niacin 3 to 4 g daily (although most effective in lowering Lp(a) and in reducing atherosclerotic heart disease mortality rates, its use may be limited because of side effects); (b) estrogen replacement after menopause, (however, concomitant progesterone therapy dilutes the effectiveness of estrogens); (c) lowering LDL with statins (generally effective in atherosclerotic heart disease but has no effect on Lp(a) levels), (d) aspirin and antibiotics (may be effective when C-reactive protein levels are high); and (e) folic acid (reduces homocysteine levels).',1 'Cisplatin was substituted and the patient achieved a complete response to therapy without further hypersensitivity.',1 'In addition, late-night salivary cortisol measurements may simplify the evaluation of suspected intermittent hypercortisolism, and they may facilitate the screening of large high-risk populations (e.g. patients with diabetes mellitus).',1 'I.c.v. injection for 9 days of either naltexone (NTX) (5, 10, 20, 40 micrograms/rat) or a selective mu peptide (CTOP) (0.125, 0.25, 0.5, 1, 3, 6 micrograms/rat) or delta (naltrindole) (NLT) (5, 10, 20 micrograms/rat) subtype opioid receptor antagonist affected sensitization to cocaine (COC) (50 mg/kg, i.p.) administered 10 min after.',1 'These results suggest that in patients whose calcium levels were normalized with IV etidronate disodium, oral etidronate disodium maintained normocalcemia significantly longer than no maintenance therapy in patients treated for hypercalcemia secondary to malignancy.',1 'However, risperidone is associated with hyperprolactinaemia which can result in amenorrhoea and sexual dysfunction.',1 'To clarify the effect of prostaglandin E1 (PGE1) or trimethaphan (TMP) on the kidney during deliberate hypotension induced with epidural block plus inhalation anesthesia, we compared renal functions and renal tubular injury between the patient with PGE1-induced hypotension (n = 22) and those with TMP-induced hypotension (n = 18) undergoing spherical acetabular osteotomy.',1 'A randomized, controlled trial of doxycycline in the treatment of acute bronchitis.',1 'In contrast, administration of high doses of cyclooxygenase inhibitors (indomethacin, piroxicam, naproxen, ibuprofen, meclofenamic acid and tiflamizole) did not affect AA-induced hind paw edema.',1 'Imatinib-induced fatal acute liver failure.',1 'Peritubal infiltration of 0.25% bupivacaine solution is efficient in alleviating postoperative pain after PCNL.',1 'Arterial blood pressure declined and 13/30 patients manifested erythema following mivacurium administration.',1 'Those who continued to experience moderate/severe pain at two hours post-dose were eligible to enter the double-blind treatment phase, during which participants treated three migraine attacks in crossover fashion (two with rizatriptan 10-mg ODT, one with placebo) after being randomly assigned to one of three treatment sequences (1 : 1 : 1 ratio).',1 'RESULTS : The greatest increase in paw edema in the first, second and fourth hours was seen in the control and iloprost groups.',1 'After adjustments for patient sex, age, size and location of hematoma, Glasgow Coma Scale score at admission, presence of intraventricular hemorrhage, history of cardiac disease, and previous use of warfarin, history of diabetes (relative risk 1.61, 95% CI 1.03-2.53, p < 0.05) and high MABP at admission (relative risk 1.01 per mm Hg, 95% CI 1.00-1.02, p < 0.05) remained independent predictors of death 3 months after ICH.',1 'The drug was well tolerated and side-effects (such as skin rash, diarrhoea, purpura and pain at the site of injection) occurred in only 4% of patients treated with cefotetan.',1 'Oestrogen increases the level of sex hormone-binding globulin that binds testosterone, resulting in lower free testosterone levels, thereby decreasing androgenic stimulation of the prostate.',1 '[Uterine sarcoma in patients receiving tamoxifen therapy. Apropos of 2 cases].',1 'Review of 40 cases of retinoblastoma revealed that histologic evidence of calcification was noted in 38 of the 40 tumors, whereas only three of 16 roentgenograms were positive for calcium.',1 'A rapid dosimetric method with controlled tidal breathing for histamine challenge was evaluated by assessment of its repeatability, by comparing to a present nondosimetric standard method, and by application to adult patients with recent asthma (n = 31), chronic asthma (n = 33), chronic cough (n = 71) or chronic rhinitis (n = 41) and to healthy controls (n = 31).',1 'All patients were treated with oral posaconazole and experienced rapid reduction of intraocular inflammation and pain, as well as resolution of the infection without additional intervention.',1 'Effects of hydrocortisone on acute β-adrenoceptor blocker and histamine induced bronchoconstriction.',1 'Comparison of vaginal misoprostol tablets and prostaglandin E2 gel for the induction of labor in premature rupture of membranes at term: a randomized comparative trial.',1 'Effect of long-acting isosorbide-5-mononitrate administration on large artery distensibility in patients with essential hypertension.',1 'BACKGROUND : Valganciclovir (VGC) has recently been proved efficacious for the prophylaxis and treatment of cytomegalovirus (CMV) infection in transplant recipients.',1 'These data demonstrate that high titer anti-motoneuronal IgG can induce severe weakness and produce similar ultrastructural features of motor axon terminals in human ALS and in mice injected with ALS IgG, and support a key role for calcium in selective vulnerability of motoneurons.',1 'MATERIALS AND METHODS : Effects of arbutin on ulcer index, gastric juice acidity, mucus content and histochemistry, gross and histological gastric lesions, nitric oxide, cytokines levels (IL-6, IL-10 and TNF-α), and thiobarbituric acid reactive substances (TBARS), were evaluated in aspirin or ethanol-induced ulcer in vivo.',1 'A 43-year-old woman with postpartum cardiomyopathy and ischemic heart disease was treated with gemcitabine for metastatic nonsmall cell lung cancer.',1 'Suppression of erythema nodosum by indomethacin.',1 'He presented severe rhabdomyolysis episode with seizure and coma after use of rosuvastatin.',1 'After initiation of therapy with sucralfate these symptoms improved in 42 patients (89%); in 6 patients there was a transitory increase in heartburn and nausea.',1 'The patient was treated with CHOP (cyclophosphamide, vincristine, doxorubicin and prednisolone), resulting in the disappearance of the mass and improvement of the hepatosplenomegaly, LDH and liver abnormalities.',1 'Among HIV patients treated for AIDS-related adjustment, major depressive disorders and other affective disorders, we assessed in an open study the feasibility of using a serotonergic antidepressant (fluvoxamine).',1 'Hydroxyurea in the treatment of HIV infection.',1 'Thus, meropenem continues to be an important option for the empirical treatment of serious bacterial infections in hospitalized patients.',1 'cyclophosphamide and azathioprine provide a reduction of morbidity in those patients afflicted with proliferative forms of lupus glomerulonephritis.',1 'METHODS : Prostate levels of testosterone and dihydrotestosterone (DHT) were measured on 5 to 10-mg biopsy specimens (18-gauge needle cores) in three groups of men with symptomatic benign prostatic hyperplasia: 15 men receiving chronic finasteride therapy versus 7 untreated controls; 4 men undergoing prostate adenomectomy to determine sampling variability (10 specimens each); and 40 men participating in a 6-month randomized trial of SPHB versus placebo, before and after treatment.',1 'We describe the unanticipated problems we encountered in collecting data for a meta-analysis comparing a new antifungal agent, fluconazole, with amphotericin B in patients with cancer complicated by neutropenia.',1 'Hypersensitivity with hepatotoxicity to mesalazine after hypersensitivity to sulfasalazine.',1 'Between March 27, 1989 and December 31, 1997, 1316 kidney transplantations alone were performed under tacrolimus-based immunosuppression at our center.',1 'We tested whether a decrease in sensory neuropeptide release is associated with an attenuated bronchoconstrictive response to field stimulation (FS; 100 stimuli, 20 V, 0.1 ms, 20 Hz) in streptozotocin (STZ)-induced diabetes.',1 'Pemphigus-like lesions induced by D-penicillamine. Analysis of clinical, histopathological, and immunofluorescence features in 34 cases.',1 'BACKGROUND : Calcium carbonate used as a phosphate binder may contribute to cardiovascular calcification.',1 'Acute retinal necrosis syndrome in a healthy 32-year-old man was treated successfully with systemic acyclovir and corticosteroids in combination with vitrectomy, 360 degrees encircling band and transscleral cryocoagulation.',1 'The sub-analysis of Heart Institute of Japan Candesartan Randomized Trial for Evaluation in Coronary Artery Disease (HIJ-CREATE) study showed that combination therapy of candesartan and amlodipine reduced the risk of major adverse cardiovascular event (MACE) by 39% (p = 0.015), as compared to that using amlodipine with non-ARB in hypertensive patients with coronary artery disease.',1 'As little as a 200-mg daily dose of modafinil is therefore an effective and well-tolerated treatment of excessive daytime somnolence in narcoleptic persons.',1 'More patients in the dolasetron group had ≥ 30% and ≥ 50% improvement in pain (42.5% and 28% respectively in the dolasetron group versus 25% and 16% in the placebo group).',1 'According to controlled studies in comorbid cardiovascular diseases, diabetes mellitus, and cerebrovascular disorders (post-stroke depression), serotonin-selective reuptake inhibitors (SSRIs), e.g., sertraline and citalopram, are preferred.',1 'Dose limiting toxicity (DLT) included ifosfamide-induced encephalopathy, febrile neutropenia and grade three mucositis.',1 'RESULTS : Adverse reactions such as ocular hypotony and choroidal effusions, recurrent cystoid macular edema, and facial rash were noted to occur within 1 to 4 weeks after starting topical latanoprost for the treatment of primary open-angle glaucoma.',1 'These results also do not support the common empiric practice of heparin treatment for women with persistent postpartum infection.',1 'Heparin-induced thrombocytopenia (HIT) is caused by antibodies against a "self" protein-platelet factor 4-bound to heparin.',1 'CONCLUSION : In the present study mirtazapine rapidly improved nausea, sleep disturbance, pain and quality of life, as well as depression in cancer patients.',1 '[Hypersensitivity to budesonide].',1 'The 0.7 M mannitol CSF infusions initially stimulated thirst but eventually depressed it, presumably due to reduction of CSF [Na].',1 'Treatment for clonidine-induced delirium involves cessation of the medication and patient observation.',1 'Risperidone as an alternative treatment for paroxysmal kinesigenic dyskinesia.',1 'Increased cell death, total cell count and protein in the bronchoalveolar fluid (BALF) in GD-exposed animals returned to normal levels following atropine treatment.',1 'Exposure either to hypoxia or the EGFR inhibitors under normoxic conditions resulted in the dephosphorylation of ribosomal protein S6, a player in the energy and nutrient-sensing pathway governed by mammalian target-of-rapamycin (mTOR).',1 'BACKGROUND : Sorafenib-induced dermatologic toxicity is common and consists primarily of dry skin, maculopapular rash, hand-foot skin reaction, and alopecia.',1 'CONCLUSIONS : Application of azelastine reduces the degree of acute radiation dermatitis without affecting the antitumoral effect of radiation therapy.',1 'In order to investigate the effect of monofluoroacetate (MFA) on renal H+ excretion, anesthetized rats under mannitol diuresis were given intraperitoneally MFA and some of the acido-basic status parameters were determined.',1 'Several clinical trials have demonstrated that these new drugs can achieve better treatment results than megestrol acetate (Megace) and may replace tamoxifen for the first-line hormonal therapy for metastatic breast cancer patients.',1 'New England Deaconess Hospital rats with transplanted pheochromocytomas developed systolic hypertension and their plasma norepinephrine concentrations were approximately 60-fold greater than controls.',1 'The vasoactive/smooth muscle reactive mediators include preformed histamine and serotonin and newly-generated platelet activating factor, slow reacting substance of anaphylaxis and prostaglandins.',1 'The aim of this overview is to provide some annotations on recently approved (cisplatin-induced anemia, preoperative anemia, zidovudine-related anemia) and possibly future (several types of malignancy and inflammation) indications for rHuEpo in non-uremic patients, leaving out the correction of anemia due to relatively uncommon disorders in the Dutch population (such as sickle cell anemia and thalassemia).',1 'The patient did not show any spontaneous sweating or pilocarpine- and nicotine-induced sweat response.',1 'We evaluated the usefulness of intravenous (IV) nefopam and tramadol in preventing and reducing the severity of shivering in patients undergoing neuraxial anesthesia for orthopedic surgery.',1 'Ketoprofen gel was significantly superior to piroxicam gel in terms of global assessment of treatment response (improvement in 74% vs 65% of patients) and the severity of the injury (38% vs 26% "greatly improved") and in improvements in stiffness (71% vs 64%), restriction of mobility (34% vs 22%), and pain on pressure (81% vs 78%) and movement (83% vs 77%).',1 'Key search terms included pain, peripheral neuropathy, diabetes, and topiramate.',1 'Protein phosphatase type-1 mRNA levels in response to starvation-refeeding and streptozotocin-diabetes.',1 'Bone marrow transplantation from matched siblings in patients with fanconi anemia utilizing low-dose cyclophosphamide, thoracoabdominal radiation and antithymocyte globulin.',1 'Aprepitant inhibited infection of macrophages with primary HIV-1 R5 strains (subtypes A, D, and H; UG275, BZ163, and BCF-KITA), while it had little effect on primary HIV-1 X4 strains (subtypes B and D, BZ167 and SE365).',1 'Whereas BK caused greater fall in the SBP (p < 0.05), DBP (p < 0.01) and duration of hypotension (p < 0.05) when administered after captopril (Fig 1 and 2).',1 'Connexin-independent ganciclovir-mediated killing conferred on bystander effect-resistant cell lines by a herpes simplex virus-thymidine kinase-expressing colon cell line.',1 'The most frequent adverse events, occurring in >1% of trospium chloride-treated patients, are dry mouth, dyspepsia, constipation, abdominal pain and nausea.',1 'Vitamin B, causing moderate to severe pain, or painless saline was injected into the buttock at a time when the subjects performance was impaired after an intravenous injection of diazepam (0.3 mg/kg).',1 'CONCLUSIONS : Disodium-clodronate given by intramuscular injection at the dose of 100 mg/die in rheumatoid patients vas effective in relieving joint pain during a two-month observation.',1 'We conclude that the concentration of calcium in plasma has the major regulatory role on plasma 1,25-(OH)2D concentrations in ruminant species when potentially conflicting signals, such as hypercalcemia and high PTH concentrations, are present simultaneously.',1 'BACKGROUND : Etomidate frequently induces myoclonus when administered intravenously with bolus injection during anesthetic induction.',1 'The side effects of peginterferon/ribavirin therapy affect virtually all organ systems, and addition of protease inhibitor can amplify these side effects (particularly anemia), and/or may lead to new ones (i.e., dysgeusia with boceprevir or skin rush with telaprevir).',1 'CONCLUSION : Use of lidocaine hydrochloride as a diluent for benzathine penicillin G does not change the penicillin concentration in body fluids and significantly reduces the pain of injection.',1 'Continuous apomorphine infusion (CAI) and neuropsychiatric disorders in patients with advanced Parkinsons disease: a follow-up of two years.',1 'Citalopram was well tolerated in spite of forced upward titration to fixed-dose levels, with a low incidence of anxiety, agitation, and nervousness.',1 'An acute episode of a malignant hyperthermia-like syndrome is described which occurred after suxamethonium and isoflurane anaesthesia in a 41-year-old healthy male patient undergoing a minor elective hand operation.',1 'Isolated thrombocytopenia associated with low dose methotrexate therapy.',1 'Penicillin dermatitis based on tuberculin-type sensitivity; report of a case with remarks on experimental sensitization to penicillin.',1 'This was because several patients in both groups required additional antibiotics for treatment of high fever (39.7%, CTX-ADD, in the cefotaxime group compared to 56.6%, BPC-ADD in the other group (p less than 0.01).',1 'Hemolytic anemia during pegylated IFN-alpha2b plus ribavirin treatment for chronic hepatitis C: ribavirin is not always the culprit.',1 'The activation of FGF-mediated bone resorption by heparin could play a role in producing the osteoporosis that has been described with heparin therapy and mastocytosis.',1 'Rats treated with morphine exhibited body weight loss upon the naloxone injection.',1 'Montelukast as a treatment modality for eosinophilic gastroenteritis.',1 'Hydroxyurea is used for sickle-cell disease patients in order to increase fetal hemoglobin synthesis and consequently decrease the severity of pain episodes.',1 'To assess the effect of prostacyclin on the diseased coronary circulation basally and, in particular, on the coronary responses to the cold pressor test, a small dose of 4 ng/kg/min and a large dose of 8 to 10 ng/kg/min was infused in 11 patients with stable angina pectoris.',1 'Varying doses of radiation, cyclophosphamide, and methylprednisolone were used to induce distinct levels of leukopenia in rats.',1 'In this population, there was a greater likelihood of erythropoietin deficiency in the patients with a hematocrit less than 30% compared with those with higher values (P less than 0.001), although there was no correlation between SIE level and the amount of cisplatin these patients received or their degree of renal impairment.',1 '[Hormonal changes in open-angle glaucoma. II. Levels of cortisol and somatotropin in serum].',1 'X-ray diffraction showed that the calcification consisted of amorphous calcium phosphate and acid calcium orthophosphate, most probably precursors of hydroxyapatite..',1 'Immunosuppression consisted of basiliximab for induction therapy and tacrolimus, mycophenolate mofetil, and prednisone for maintenance therapy.',1 'RESULTS : The unadjusted hazard ratio for risk of death (dofetilide/placebo) was 1.4 with 95% confidence interval 0.4-5.1.',1 'CONCLUSIONS : Our results indicate that subcutaneous injection followed by oral administration of sumatriptan produces prompt and continuous analgesia in patients with trigeminal neuralgia.',1 'We chose to utilize blast cell samples obtained from patients with childhood acute lymphoblastic leukemia (ALL) to study their interaction with Doxorubicin (DX) and Daunorubicin (DN) as representative drugs, evaluating cellular drug uptake by flow cytometry.',1 'Prospective evaluation of body surface area as a determinant of paclitaxel pharmacokinetics and pharmacodynamics in women with solid tumors: Cancer and Leukemia Group B Study 9763.',1 'A total of 65 patients who were scheduled to receive two cycles of high-dose cyclophosphamide, etoposide, cisplatin (CEP) chemotherapy were randomized to receive imipenem either at presentation of neutropenia (immediate imipenem arm, prophylactic arm) or at commencement of neutropenic fever (delayed imipenem arm, therapeutic arm).',1 'In this report, we describe a patient receiving lenalidomide in whom dyspnea, fever, hypoxia, and diffuse pulmonary infiltrates developed.',1 'The pseudomembranous colitis developed 12 days after the last dose of ampicillin was given to the baby.',1 'At present, aliskiren should be considered in hypertensive patients not sufficiently controlled or intolerant to other inhibitors of renin-angiotensin system.',1 'Although valproic acid (VPA) a proven anticonvulsant agent thought to have relatively few side-effects VPA has been referred as the third most common xenobiotic suspected of causing death due to liver injury.',1 'Two separate sets of experiments were performed on female Wistar rats made diabetic with streptozotocin: (1) a time-course study where groups of three animals were removed at weekly intervals, up to 4 weeks after induction of diabetes, with an age-matched group of control (normal) animals kept for 4 weeks; (2) six further animals were made diabetic and kept for 7 weeks; three of these were given insulin in the final week.',1 'Mifepristone administered for 3 months or longer to women with uterine leiomyomas, is associated with a reduction in pain and bleeding with improvement in quality of life and decrease in fibroid size.',1 'Methylphenidate and imipramine are the two most widely used drugs for the treatment of daytime somnolence and cataplexy, respectively.',1 'Vomiting and fatigue were significantly worse with PCI gemcitabine.',1 'YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma.',1 'When rats with streptozotocin-induced diabetes were treated with OA (100 and 200 mg/kg body mass per day, for 40 days), the changes in blood glucose levels and in oral glucose tolerance tests showed that hypoglycemia was more pronounced in OA-treated groups than in the diabetic control rats, and that the levels of triglyceride, total cholesterol, and low-density lipoportein cholesterol in OA-treated rats were lower than those in the diabetic control rats, whose high-density lipoprotein cholesterol increased.',1 'Moreover, our findings suggest the presence of a calcitonin-dependent calcium homeostatic mechanism, that protects against hypercalcemia due to tumor osteolysis.',1 'Infection significantly upregulated both molecules, but no differences were detected between estradiol- and testosterone-treated groups.',1 'The aim of this study was to evaluate the effect of a 24-week treatment with the ACE inhibitor moexipril (15 mg once daily) on the regression of LVH in hypertensive patients.',1 'Stress echocardiography in the detection of myocardial ischemia. Head-to-head comparison of exercise, dobutamine, and dipyridamole tests.',1 'CONCLUSIONS : We conclude that sildenafil, vardenafil, and tadalafil were equally efficacious in causing pulmonary artery relaxation, but only tadalafil inhibited hypoxic pulmonary vasoconstriction and attenuated hypoxia-induced pulmonary artery TNF-alpha and IL-1beta expression.',1 'The mechanism by which progesterone blocked the development of ACTH hypertension appears to be related to the ability of progesterone to block the essential mineralocorticoid component of the adrenocortical steroids involved in the development of ACTH hypertension.',1 'Inhibitory effect on hepatitis B virus in vitro by a peroxisome proliferator-activated receptor-gamma ligand, rosiglitazone.',1 'OBJECTIVE : To evaluate the effect of prostaglandin E1 (PGE1) induced hypotension on spinal cord blood flow (SBF) during spinal surgery.',1 'Lowest (20%) and highest (88%) ataxia occurred when cetirizine was administered, respectively, at 17 and 5 HALO.',1 'Before immunotherapy, all patients had a complete evaluation of the severity of asthma by symptom-medication scores and a pulmonary function test, as well as a study of other triggering factors by checking on seasonal and perennial allergens, sinusitis, and other possible causes, such as aspirin intolerance; 196 patients were investigated between 9 and 12 months after the onset of the survey by means of pulmonary function tests and symptom-medication scores.',1 'We conclude that there is no clinical indication that the dosage of atracurium and vecuronium during inhalation anesthesia should be reduced, but the doses of pipecuronium and pancuronium should be reduced when prolonged paralysis is not desired.',1 'In addition, beta blockers and clonidine are useful, as both effectively combat the hypertension and tachycardia commonly associated with withdrawal.',1 'Alopecia and drug eruption of the scalp associated with a new beta-blocker, nadolol.',1 'The other patient, a 72-year-old woman who was taking tamoxifen citrate for prevention of breast cancer relapse, experienced cerebral embolism just 2 months after beginning tamoxifen.',1 'Eosinophilia and pancreatitis are both previously unreported side effects or associated findings of thalidomide treatment.',1 'With the introduction of the erection-supporting oral drug sildenafil (Viagra) the development of somatic treatments of male sexual dysfunction has reached a temporary peak.',1 'Prostaglandin E1 and survival in patients with the adult respiratory distress syndrome. A prospective trial.',1 'The present data suggest that nicotine effects on the RAS might collaborate to the development of neurogenic hypertension in SHR through modulation of glial cells.',1 'Streptozotocin (STZ)-induced diabetes mellitus (DM) offers a very cost-effective and expeditious technique that can be used in most strains of rodents, opening the field of DM research to an array of genotypic and phenotypic options that would otherwise be inaccessible.',1 'We report a case of nitrofurantoin drug fever associated with its use, following sexual intercourse, for chemoprophylaxis of UTI.',1 'Acute hepatitis associated with use of paroxetine.',1 'Polyuria is a highly prevalent, distressing and impairing side-effect of long-term lithium treatment, requiring due attention.',1 'OBJECTIVE : To compare the outcome of ropivacaine plus sufentanil for patient-controlled epidural analgesia between nulliparous women presenting in latent and active labor.',1 'The next series of experiments showed that acute administration of the opioid analgesic, morphine (5.6 mg/kg; IP), attenuated PGE(2)-induced thermal hypersensitivity and reversed the increase in extracellular 5-HT observed in the RVM.',1 'Reinduction of atrial tachycardia after administration of atropine was not possible.',1 'One infant in the ibuprofen group died from sepsis and one in the indomethacin group died as a result of NEC.',1 'Among new cases, bleeding of gastric ulcer was less common in smokers (OR = 0.6), and more common in daily users of aspirin (OR = 2.1) and, to a lesser extent, in daily users of anti-arthritic drugs (OR = 1.5), and in patients aged 60 or more years (OR = 2.3) independent of usage of the above drugs.',1 'Argatroban anticoagulation during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia.',1 'The purpose of this study was to estimate the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection and the related factors in male amphetamine-inhaling abusers.',1 'Effects of atorvastatin on warfarin-induced aortic medial calcification and systolic blood pressure in rats.',1 'There may be a need to re-evaluate the appropriateness of nifedipine as the first line anti-hypertensive drug and the usefulness of NSAID-antacid and amoxycillin-cloxacillin combinations.',1 'Oral pathology quiz. Case number 2. Nicotine stomatitis.',1 'Medical management of uterine fibroids with medroxyprogesterone acetate (Depo Provera): a pilot study.',1 'The potency of these new taxoids were examined for their inhibitory activity for microtubule disassembly and also for their cytotoxicity against murine P388 leukemia cell line as well as doxorubicin-resistant P388 leukemia cell line (P388/Dox).',1 'After one course of sunitinib, mental status was altered due to hypercalcemia (serum calcium level was 18.6 mg/dl and PTH-rP was 3.7 pmol/l).',1 'The purpose of this evaluation was to investigate the efficacy of high-dose chemotherapy with thiotepa, melphalan, and carboplatin (TMCb), and of autologous peripheral blood stem cell (PBSC) infusion in patients with aggressive non-Hodgkins lymphoma (NHL) or Hodgkins disease (HD).',1 'Chronic treatment with amlodipine modulates adrenocortical angiotensin II receptors in spontaneously hypertensive rats.',1 'The present study was undertaken to compare the strategy of ventricular rate control versus maintenance of sinus rhythm in rheumatic atrial fibrillation, and to evaluate the role of amiodarone in this patient population.',1 'We hypothesized that insulin glargine would improve blood glucose control and weight in patients with CFRD without causing hypoglycemia.',1 'In conclusion, both nebivolol and zofenopril protected rats from ischemia-induced brain injury.',1 'Metformin is associated with a low risk of lactic acidosis, but should not be used in patients with elevated serum creatinine or those being treated for congestive heart failure.',1 'Management of lithium induced diabetes insipidus in manic-depressive illness: a case report.',1 'The most frequent adverse events of sorafenib were hand-foot skin reaction and diarrhea.',1 'Although both rizatriptan and zolmitriptan are effective in the treatment of migraine and cluster headaches, they may induce peripheral vasospasm leading to renal infarction.',1 'Transient diaphragmatic paralysis by continuous para-phrenic infusion of bupivacaine: a novel technique for the management of residual spaces.',1 'OBJECTIVE : To determine if epinephrine (EPI) added to a solution of bupivacaine (BUP) injected for use in superficial cervical plexus blockade (SCPB) lowers plasma BUP concentrations after injection and whether this addition of EPI resulted in tachycardia, cardiac arrhythmias, or both.',1 'Recent experience suggests that the atypical neuroleptics, olanzaine, risperidone, and quetiapine, are also useful for controlling severe agitation in elderly demented nursing home residents.',1 'Paresthesia, upper respiratory tract infection, somnolence, and nausea were the most common AEs with topiramate.',1 'Thiopurine methyltransferase deficiency must therefore be suspected when early and severe leukopenia occurs during azathioprine therapy.',1 'Cholestatic hepatitis developed in two patients while they were receiving erythromycin ethylsuccinate.',1 'Thus, metoprolol as a beta 1-selective betablocker is not contraindicated in patients with intermittent claudication.',1 'Several genes, including TRPM-2, (testosterone repressed prostate message), RVP.1, fos, and myc, have been shown to be induced in the prostate during this process.',1 'OBJECTIVE : To examine the association of methotrexate (MTX) and tumour necrosis factor (TNF) antagonists with the risk of infectious outcomes including opportunistic infections in patients with rheumatoid arthritis (RA).',1 'BACKGROUND : We evaluated the effect and safety of the immediate postoperative continuous infusion of remifentanil at two doses in patients undergoing laparoscopic-assisted vaginal hysterectomy (LAVH) with alfentanil-based patient-controlled analgesia (PCA).',1 'Dobutamine-induced hypotension has been disregarded as a marker of more severe functional abnormalities in patients with suspected coronary artery disease.',1 'The effect of indomethacin gel on UVB and UVC erythema was assessed objectively using a reflectance instrument.',1 'In fertility studies groups of sexually mature male rats were given 93 or 326 mg/kg of gemfibrozil for 61 days and females were given 94 or 318 mg/kg for 15 days prior to mating within treatment groups.',1 'Coadministration of HP and furosemide at lower doses (1.67 mg/kg, i.v. and 5 mg/kg, oral) reduced the hypotensive effect, accompanying the enhanced elimination of HP from plasma after a single i.v. and repeated oral treatment when compared to the result obtained with HP alone.',1 'The antinociceptive effects of intravenous dexmedetomidine in colorectal distension-induced visceral pain in rats: the role of opioid receptors.',1 'OBJECTIVE : The aim of this study was to investigate the effectiveness and safety of the selective serotonin reuptake inhibitor fluvoxamine (Flevarin) in patients with a chronic pain syndrome due to hip and knee arthritis.',1 'Clinical effects of intravenously administered prostaglandin E1 in patients with rest pain due to peripheral obliterative arterial disease (POAD)--a preliminary report on a placebo-controlled double-blind study.',1 'MEASUREMENTS AND MAIN RESULTS : Misoprostol was associated with mild abdominal cramps in four women (20%) and vaginal bleeding in another.',1 'Randomized trial of cefepime monotherapy or cefepime in combination with amikacin as empirical therapy for febrile neutropenia.',1 'Cisplatin is a neurotoxic chemotherapeutic agent known to cause sensory peripheral neuropathy or ototoxicity.',1 'Neostigmine resulted in a moderate effect on motor weakness at doses of 3 and 10 microg.',1 'The addition of specific antigen to IgE-sensitized human lung tissue causes the secretion of the mediators histamine and slow-reacting substance of anaphylaxis.',1 'Here, we examined the therapeutic effectiveness of 17beta-estradiol and raloxifene, a selective estrogen receptor modulator, for preventing functional and histological alterations in the kidneys of db/db mice, a model of type 2 diabetes.',1 'Cortical mechanisms of cocaine sensitization.',1 'However, use of lactulose is limited by diarrhea and flatulence.',1 'Minocycline, a semi-synthetic tetracycline, was injected into one hind joint of twenty-two rabbits with zymosan-induced arthritis, while the contralateral joint served as a control.',1 'Patients switching to bivalirudin had similar rates of ischemia (6.9% vs. 7.4%, p = 0.52), less major bleeding (2.8% vs. 5.8%, p < 0.01), and improved net clinical outcomes (9.2% vs. 11.9%, p < 0.01) than those on consistent UFH/ENOX plus a GP IIb/IIIa inhibitor.',1 'Cutaneous hypersensitivity to penicillin.',1 'Seven trials (six of them still ongoing) have provided insight into the effects of the third-generation calcium antagonist, amlodipine, on mortality and end-organ damage in patients with hypertension or other forms of cardiovascular disease.',1 'METHODS : A series of patients (N = 33) diagnosed of peritoneal carcinomatosis for epithelial ovarian cancer (stage III) from January 1997 to December 2004 submitted to radical surgery-peritonectomy and HIIC with paclitaxel was included in this study; 19 primary ovarian cancer and 14 recurrent ovarian cancer.',1 'In addition, complications including osteoporosis and heparin-induced thrombocytopenia are relatively rare with low molecular weight heparins compared to unfractionated heparin.',1 'Intramuscular olanzapine in patients with borderline personality disorder: an observational study in an emergency room.',1 'CONCLUSIONS : Past treatments for testicular cancer are associated with an increased risk of leukemia, with evidence for dose-response relationships for both radiotherapy and cisplatin-based chemotherapy.',1 'This was a randomized double-blind, multiclinic, parallel, three treatments group study to compare the safety and efficacy of a fixed-ratio combination of enalapril/hydrochlorothiazide (E/HCTZ: 20/12.5-40/25 N = 46) to enalapril (E = 20-40 mg, N = 49) and hydrochlorothiazide (HCTZ: 12.5-25 mg, N = 51) once daily, in the treatment of patients with moderate to severe essential hypertension (100 less than or equal to supine diastolic blood pressure less than or equal to 120 mmHg).',1 'Induction of diabetes in NOD<-->C57BL/6 embryo aggregation chimeras by cyclophosphamide through preferential depletion of C57BL/6 lymphocytes.',1 'Mefloquine can cause dose-related serious neuropsychiatric toxicity and pyrimethamine-dapsone is associated with agranulocytosis, especially if the recommended dose is exceeded.',1 'The group I was composed of 8 patients with amiodarone induced pneumonia who were taking the drug for an average of 16.88 months (average of 386.60 mg a day).',1 'These results suggest that hypoxia may stimulate pulmonary prostacyclin synthesis; a pulmonary vasodilator, prostacyclin may help modulate hypoxic vasoconstriction in the lung.',1 'Elymoclavine inhibited the picroroxin and electroshock convulsive seizures but potentiated the pentylenetetrazol ones in mice as these effects were differently influenced by pimozide, haloperidol, 5-HT, atropine and phentolamine.',1 'OBJECTIVE : To determine the effect of the coadministration of the multidrug resistance (MDR) modulators cyclosporin A (CyA) alone or plus dexverapamil (D-Ver) on idarubicin (IDA) pharmacokinetics in patients with acute leukemia.',1 'METHODS AND RESULTS : Forty-nine patients with predischarge left ventricular ejection fraction <45% after acute myocardial infarction were evaluated in a double-blind, randomized, placebo-controlled, parallel group study (selected from the database of the Carvedilol Heart Attack Pilot Study: CHAPS).',1 'The schedule-dependent interaction of paclitaxel and cisplatin was studied in four human carcinoma cell lines: non-small cell lung cancer, A549; breast cancer, MCF7; ovarian cancer, PA1; and colon cancer, WiDr cells.',1 'Plasma glucose, insulin, free fatty acids (FFA), tumour necrosis factor-alpha and cortisol by standardised assays.',1 '[Effect of sodium valproate, phenobarbital and diazepam during their combined use on convulsions induced by electroshock in mice].',1 'The objective of this study is to evaluate the efficacy and safety of rhTNFR:Fc: a recombinant tumor necrosis factor receptor:Fc fusion protein compared with methotrexate (MTX) in patients with rheumatoid arthritis in China.',1 'The most common adverse events for quetiapine were dry mouth, somnolence, and weight gain, while lithium was associated with tremor and insomnia.',1 '[Highly advanced gastric cancer that responded to neoadjuvant combination chemotherapy with docetaxel/CDDP/S-1 (DCS)].',1 'LH-RH analogues have come into use to suppress the synthesis of testosterone by the testes and to induce palliation in advanced prostate cancer.',1 'Cortisone and corticotropin (ACTH) in adequate doses usually promptly relieve allergic rhinitis, bronchial asthma, atopic eczema, urticaria, drug reactions and poison oak and ivy dermatitis.',1 'AIMS : The primary objective of this study was to determine whether hepatic function improves in patients with advanced liver disease after 1 month of daily ciprofloxacin therapy.',1 'In high doses, naloxone itself causes generalized clonic convulsions.',1 'Quercetin, a bioflavonoid, attenuates haloperidol-induced orofacial dyskinesia.',1 'Therefore, progesterone and 17alpha-hydroxyprogesterone as endogenous steroids might induce PD-ECGF-related angiogenic potential in uterine endometrial cancer cells, but not MPA as a synthetic steroid.',1 'This report describes dyspnea, cough, erythema multiforme, and a diffuse pulmonary interstitial infiltrate associated with eosinophilic alveolitis in a 67-year-old man taking diclofenac sodium (Voltaren).',1 'Chlormethiazole suppressed the behavioral expression of cocaine-kindled seizures and prevented the development of sensitization to the convulsant effects of cocaine.',1 'The death of ouabain-treated cells was independent of inhibition of RNA and protein synthesis with actinomycin D and cycloheximide.',1 'Clonidine 4 and 6 micrograms/kg significantly attenuated hemodynamic and adrenergic reactions to stress, reduced pharmacologic interventions, and increased sedation.',1 'We, therefore, do not recommend chlorpromazine in the routine management of patients with watery diarrhea, however, it may be useful in treatment of children with severe cholera when added to standard treatment of hydration and tetracycline.',1 'In conclusion, celecoxib exhibited beneficial effects against the development of monocrotaline-induced pulmonary artery hypertension and right ventricular hypertrophy.',1 'CONCLUSION : Long-term use of transdermal buprenorphine for chronic noncancer pain does not impair driving ability, but because of the individual variability of test results, an individual assessment is recommended.',1 'After 150 minutes, iloprost-treated rats had a higher Svo2 and lesser edema as compared with animals with CHF inhaling NO or untreated rats with CHF, although differences in wet/dry weight ratio did not reach statistical significance (p < 0.06).',1 'Doxorubicin (DOX) is an effective antitumour agent against a variety of human malignancies but is associated with deleterious side effects, including myocardial damage and heart failure.',1 'We performed a literature search of all available English-language articles published on MEDLINE between January 1966 and July 2008 using the key terms "acute pancreatitis", "interferon" and "ribavirin"; only four papers were found with a total of 13 reported cases demonstrating acute pancreatitis developed during treatment for CHC.',1 'It was stated that decreased level of haircalcium considerably precedes the start of the calcification process in vessels, thus its measuring may call attention to balance troubles of calcium metabolism in time.',1 'Permanent intrinsic B cell immunodeficiency caused by phenytoin hypersensitivity.',1 'The threshold for clonic PTZ seizures was increased by CPP only at high doses (20 mg/kg) which induced ataxia and marked motor impairment in the chimney test, whereas both diazepam and phenobarbital were active in this test at doses which exerted no side-effects.',1 'Accordingly, 11 inbred mouse strains were tested for inhibition of nociception by gabapentin or pregabalin (50-300 mg/kg, i.p.) in two different preclinical assays of inflammatory pain, the formalin test (5% formalin; 20 microl) and zymosan thermal hyperalgesia on the paw-withdrawal test (3 mg/ml zymosan; 20 microl).',1 'BACKGROUND : We hypothesized that increased myocardial oxygen demand resulting from hypotension and reflex tachycardia unmasking a reduced endocardial myocardial blood flow (MBF) reserve is the mechanism of dipyridamole-induced regional dysfunction in chronic coronary artery disease.',1 'There were highly significant associations between the cortisol response and both headache severity and duration, independent of m-CPP plasma levels.',1 'METHODS : Thirty-six children with mean age 38.6 +/- 15.9 months who had MS infection brushed once daily with 0.2% chlorhexidine (CHX) gel for a period of 6-12 months.',1 'OBJECTIVE : Although paclitaxel is widely used as a systemic agent for the treatment of solid tumors, limited information is available concerning administration of this taxane by regional techniques.',1 'Severe hypotension associated with combined lithium and chlorpromazine therapy: a case report and a review.',1 'We did not observe heparin-induced thrombocytopenia.',1 'It is concluded that, in the mouse, sensitization to the locomotor activating action of cocaine is associated with differential changes in the NMDA receptors of the central nervous system.',1 'Comparison of four antiemetic regimens for the treatment of cisplatin-induced vomiting.',1 '[Hypersensitivity due to topical use of silver sulfadiazine on burn wounds (report of 6 cases)].',1 'Postoperative analgesia for Caesarean section using epidural methadone.',1 'In conclusion, long-term antianginal therapy with propranolol or nicardipine improved several markers of myocardial ischemia in approximately two-thirds of the patients.',1 'In addition to preventing rejection, mammalian target of rapamycin inhibitors directly suppress signaling pathways leading to PTLD and may be effective monotherapy for preventing rejection and suppressing PTLD.',1 'Case report of long-term lithium for treatment and prevention of clozapine-induced neutropenia in an African American male.',1 'Sorafenib combined with rapamycin appears to be a promising strategy for the effective treatment of melanoma and merits clinical investigation.',1 'The proportion of patients with bone loss of >2% per annum at the LS and FN was higher in the budesonide group than in the nonsteroid group (p < 0.001) and prednisone group (p < 0.05).',1 'The actions of prolactin, insulin and cortisol on the conversion of testosterone to dihydrotestosterone in the cultured rat ventral prostate were examined in conditions in thich they have been demonstrated to act synergistically with testosterone on the macromolecule synthesis of the prostate.',1 'These results indicate that i) insulin is produced by testicular cells, ii) insulin is depleted by streptozotocin-induced diabetes, and iii) that insulin depletion and hyperglycemia do not regulate the expression of GLUT8 in testes.',1 '[Surgical exploration of deafness due to thalidomide].',1 'OBJECTIVES : To determine incidence and identify predisposing factors for sterile hemorrhagic cystitis (SHC) in dogs with lymphoma that were treated with cyclophosphamide and to evaluate whether furosemide administered i.v. concurrently with cyclophosphamide decreased the incidence of SHC.',1 'In obstetrics, misoprostol has been administered for induction of first and second trimester abortion, for induction of labor in the third trimester, and to control postpartum hemorrhage.',1 'Compared with controls, patients who received prednisone had more rapid rates of improvement from baseline in pain, mental well-being, and disability scores.',1 '[Presence of antibodies responsible for manifestations of penicillin sensitization of a delayed type. Preliminary report].',1 'Ephedrine also increased scores on a number of mood scales reflecting CNS stimulation and anxiety.',1 'Role of lithium-ADH interaction in lithium-induced polyuria.',1 'Chi Square tests identified statistically significant incidence differences of anemia (p < 0.05) between the zidovudine group and the stavudine group.',1 'The percentage of patients reporting > or =50% decrease in depressive symptoms did not differ between groups, but depressive symptoms improved more with bupropion SR than with placebo among patients with a history of major depression (p < 0.05, weeks 4 to 26).',1 'To evaluate the natural history of lipid abnormalities in children post-transplantation, this study utilized a cohort of 29 patients who were all treated with the same three- drug maintenance immunosuppression (cyclosporine, azathioprine, and prednisone) and whose dosing regimen was rigidly controlled.',1 'RESULTS : Ten of 27 patients achieved significant pain relief after receiving 300 mg/day of intravenous clodronate for 10 days.',1 'IMPLICATIONS: A randomized, controlled clinical trial of 115 patients undergoing dental restoration indicated that an anesthetic technique using remifentanil provided quality of emergence comparable to and no greater incidence of vomiting than a nonopiate technique.',1 'A simple device for measuring ventilatory function, the airflowmeter, was found to be at least as sensitive as the Wright peak-flow meter in detecting histamine-induced bronchoconstriction in asthmatic patients.',1 'In mice with DSS-induced colitis, EC-M17, metronidazole, and EC-M17 plus metronidazole significantly reduced DAI and colonic histology scores.',1 'The arrhythmogenic effects of cardiac anaphylaxis could be reproduced by exogenous histamine.',1 'Fluoroquinolone phototoxicity: a comparison of moxifloxacin and lomefloxacin in normal volunteers.',1 'Hepatocellular carcinoma in patients with cirrhosis: qualitative comparison of gadobenate dimeglumine-enhanced MR imaging and multiphasic 64-section CT.',1 'Aliskiren (with or without other agents) provides significant and prolonged blood pressure reductions in a broad range of hypertensive patients and is well tolerated.',1 '(v) High-multiplicity-of-infection passage of TR339 on BHK cell cultures resulted in rapid coselection of high-affinity binding to BHK cells and attachment to heparin-agarose beads.',1 'Therefore, our data suggest that lithium chloride protects the retinal neural cells from nutrient deprivation in vitro, which may be similar to the mechanism of cell death in glaucoma.',1 'Deviation of cortisol metabolism in favour of its 6 beta-hydroxylated derivative was demonstrated in two patients with adrenal failure receiving substitution corticosteroid therapy and rifampicin.',1 'To calculate the accuracy of dobutamine infusion as a stress test to detect coronary lesions, 90 patients with angina and nine asymptomatic subjects with nonsignificant coronary lesions were submitted to a dobutamine test and coronary arteriography.',1 'The side effects of ME 2303 such as weight loss were as mild as those with doxorubicin, except in the female mice administered 30 mg/kg of ME 2303 and no other adverse effect was observed.',1 'Deficiencies of both protein C and protein S, known risk factors for the more frequently encountered coumarin necrosis, may predispose patients to this complication of heparin therapy as well.',1 'Pain in oxaliplatin-induced neuropathy--sensitisation in the peripheral and central nociceptive system.',1 'This fluorometer was then employed to assess the redox state in rats with streptozotocin-induced diabetes.',1 'During a mean follow-up of 8+/-3 months post-ablation, atrial fibrillation recurred in two of 10 patients on continued amiodarone therapy after successful isthmus ablation.',1 'RESULTS : Plasma norepinephrine levels, but not plasma renin activity, aldosterone, epinephrine, or vasopressin levels, were significantly higher in the hypertension with compression group (389+/-53 pg/ml) than in the hypertension without compression group (217+/-38, P<0.05) or in the normotension group (225+/-30, P<0.05).',1 'In the Appropriate Blood pressure Control in Diabetes (ABCD) trial, 470 patients with hypertension and type 2 diabetes who were randomized to long-acting nisoldipine had an adjusted sevenfold increased risk for acute MI compared to those randomized to enalapril (RR 7.0; 95% CI 2.3-21.4).',1 'Fecal tumor necrosis factor alpha (TNF-alpha) is elevated in microsporidiosis; therefore, thalidomide, an anti-TNF-alpha agent, was used as therapy.',1 'Amphetamine had no effect on anxiety-like behavior.',1 'Successful Use of Alternative Anticoagulants in the Management of Heparin-induced Thrombocytopenia with Thrombotic Complications: Report of 5 cases and review of literature.',1 'Cisplatin, a commonly used antineoplastic agent, destroys the sensory hair cells in the cochlear and vestibular system leading to irreversible hearing loss and balance problems.',1 'OBJECTIVE : To examine quantitatively the association between glucose intolerance including diabetes mellitus and the use of the atypical antipsychotics clozapine, olanzapine or risperidone, and to identify possible risk factors for the development of glucose intolerance during treatment with these drugs.',1 'The adjuvant effects of imiquimod for a herpes simplex virus (HSV) vaccine were evaluated.',1 'BACKGROUND : The aim of this study was to observe the effects of neoadjuvant therapy with irinotecan and 5-fluorouracil (5-FU)/folinic acid (FA) on the resection rate and survival of colorectal cancer patients with initially unresectable hepatic metastases.',1 'The systemic azoles, itraconazole and fluconazole, are generally safe and effective agents in HIV-infected patients with oropharyngeal candidiasis.',1 'Our objectives were to compare susceptibility to ventricular arrhythmias in rats with prolonged duration of diabetes induced by streptozotocin (45 mg/kg, i.v.), utilising two different models.',1 'Events causing olanzapine discontinuation were pneumonia, sedation, and hypomania.',1 'These data are compatible with increased basal exocytotic dopamine release and accelerated neuronal and renal (extraneuronal) dopamine generation from administered DOPA in borderline hypertension.',1 'Premedication with clonidine, in comparison with midazolam, exhibited a superior effect on sedation at induction (OR=0.49 [0.27, 0.89]), decreased the incidence of emergence agitation (OR=0.25 [0.11, 0.58]) and produced a more effective early post-operative analgesia (OR=0.33 [0.21, 0.58]).',1 'The aim of this study was to compare the esophageal transit of the commercial film-coated risedronate tablet and a round uncoated tablet resembling the alendronate 10 mg tablet which is reported to cause esophagitis if ingested with little to no water.',1 'The results suggest that either prevention of NO overproduction or protection against liver damage is responsible for recovery of bradycardia after naltrexone administration.',1 'The majority of this cocaine is used intranasally prior to or during surgical procedures to provide mucosal vasoconstriction and analgesia.',1 'Serotonin and dopamine sensitization in the nucleus accumbens, ventral tegmental area, and dorsal raphe nucleus following repeated cocaine administration.',1 'This is the first reported case of B. bronchiseptica infection in a patient receiving temozolomide.',1 'Before midazolam, hypoxia to an SaO2 of 75 +/- 2% was associated with a 23 +/- 3 beats/min increase in heart rate; after midazolam, the increase in heart rate with hypoxia was only 4 +/- 2 beats/min (P less than 0.001).',1 'It appears that methotrexate, in the doses normally used to control psoriasis, may cause cirrhosis if treatment is prolonged and that liver biopsy is necessary for evaluation of liver damage in these patients.',1 'In a multivariate logistic regression analysis, symptomatic heart failure was the most important correlate of impaired QOL (SF-36) across all eight subscales [odds ratios (ORs) ranging from 5.21 to 22.53)], whereas psychotropic medication, age, comorbidity, amiodarone, and ICD shocks all correlated to a lesser extent.',1 'In the prazosin period 8 patients continued to complain of dizziness after the first 24 h. With bendrofluazide serum-potassium levels fell below 3-6 mmol/l in half the patients within the first two weeks of treatment.',1 'Testosterone fails to prevent skeletal muscle atrophy from glucocorticoids.',1 'Weight gain and cardiovascular risk factors during smoking cessation with bupropion or nicotine.',1 'Despite a non-negligible bleeding risk, the combination of aspirin-clopidogrel has provided satisfactory results in conditions at high thrombotic risk but rather disappointing results in the long-term treatment of chronic stable cardiovascular disease.',1 'Pharmacokinetic and clinical studies in patients with cimetidine-associated mental confusion.',1 '[Use of atropine in acute myocardial infarction].',1 'Reduced reactivity of postsynaptic alpha 2-adrenoceptors seems to be of great importance since treatment of vasopressin-hypertensive rats with 6-hydroxydopamine resulted in a decrease of blood pressure and reappearance of the sensitivity of postsynaptic alpha 2-adrenoceptors to clonidine.',1 'These data suggest that ROS play a causal role in the development and maintenance of paclitaxel-induced pain, but such effects cannot be attributed to superoxide radicals alone.',1 'Phase II of doxorubicin/taxol in metastatic breast cancer. Argentine Multicenter Taxol Group.',1 'Photosensitivity and hyperpigmentation in amiodarone-treated patients: incidence, time course, and recovery.',1 'D-Penicillamine improved laparoscopic and histological findings of the liver in a patient with Wilsons disease: 3-year follow-up after diagnosis of Coombs-negative hemolytic anemia of Wilsons disease.',1 'AUTHORS CONCLUSIONS : Fluticasone given at half the daily dose of beclomethasone or budesonide leads to small improvements in measures of airway calibre, but it appears to have a higher risk of causing sore throat and when given at the same daily dose leads to increased hoarseness.',1 'Postoperative hemorrhage associated with carbenicillin administration. Report of two cases and review of the literature.',1 'Glutamine may reduce paclitaxel-induced toxicity, while some patients with tacrolimus or suramin-induced demyelinating neuropathy may respond to intravenous immunoglobulin or plasmapheresis.',1 'FSH time-concentration profiles before and after administration of 0.25 mg cetrorelix in the gnRH-antagonist multiple-dose protocol for ovarian hyperstimulation.',1 'Malignant hyperthermia is a potentially fatal pharmacogenetic disorder triggered by volatile anesthetics (halothane, enflurane, isoflurane) and/or succinylcholine.',1 'Importance of initial environments in the development of ambulatory sensitization to methamphetamine and cocaine in mice.',1 'In all patients, we obtained venous blood samples for epinephrine (an index of adrenomedullary catecholamine release) and norepinephrine (an index of neuronal activity) both in resting conditions and at peak dipyridamole, ie, at the first minute after termination of dipyridamole infusion in negative cases or in the presence of obvious ischemia in positive cases (ie, as soon as a regional ventricular dyssynergy or an ST segment depression greater than 0.1 mV appeared).',1 'Multiple regression analysis confirmed that aspirin-intolerant asthma (AIA) was strongly associated with NFA.',1 'We describe the available information on 50 cough episodes attributable to captopril and 18 episodes attributable to enalapril reported to the Spanish Drug Surveillance System.',1 'At present, the circle of agents with an established chemopreventive effect is restricted to tamoxifen and raloxifene in breast cancer, finasteride in prostate cancer, and celecoxib in colon polyp prevention.',1 'CONCLUSION : We have described and evaluated a software engine to justify the conclusions of RENEX for detecting renal obstruction with MAG3 renal scans obtained before and after the administration of furosemide.',1 'The effect of calcium on Fas-mediated apoptosis and secondary necrosis of Jurkat cells.',1 'BACKGROUND : The objective of this study was to evaluate the activity and safety of oral capecitabine in combination with docetaxel and epirubicin (TEX) as first-line treatment for patients with locally advanced/metastatic breast carcinoma.',1 'Nicotine substitution partially controls the withdrawal syndrome, sometimes very intense in smokers with pharmacological dependence.',1 'The recent demonstration that the female hormone, 17beta-estradiol prevents UVR-induced suppression of the contact hypersensitivity response caused by the release of immunosuppressive cytokines (IL-10) from keratinocytes might thus explain why the risk of PLE is higher in females than in males and why the risk decreases in women after the menopause.',1 'Megestrol acetate v tamoxifen in advanced breast cancer in postmenopausal patients.',1 'METHOD : Nineteen male and female DSM-IV-defined schizophrenic patients who were clinical responders to risperidone but were suffering from symptomatic hyperprolactinemia were treated with cabergoline, 0.125 to 0.250 mg/week for 8 weeks.',1 'Our results show that oral administration of candesartan after transient focal ischemia reduced infarct volume at doses that showed little effect on BP.',1 'Multivariate-adjusted hazard ratios of hearing loss in regular users (2+ times/week) compared with men who used the specified analgesic <2 times/week were 1.12 (95% confidence interval [CI], 1.04-1.20) for aspirin, 1.21 (95% CI, 1.11-1.33) for NSAIDs, and 1.22 (95% CI, 1.07-1.39) for acetaminophen.',1 'The duration of analgesia was nearly equivalent in all sufentanil-alone groups (83, 102, and 99 minutes); a dose-response effect was more apparent in the bupivacaine group (35, 42, and 74 minutes; P = .006) and the combination group (60, 79, 101 minutes; P = .028).',1 'Thrombocytopenia and a slight increased risk for anemia were evident at > or =2 weeks of linezolid treatment.',1 'A recent controlled clinical trial suggested a role for amantadine as a treatment for pathological gambling in patients with Parkinson disease (PD).',1 'We experienced two cases of advanced gastric cancer effectively treated by sequential therapy of docetaxel and paclitaxel.',1 'Naloxone reversal of ischemic arrhythmia is stereospecific and suggests role of endogenous opioid peptides in ischemic heart disease.',1 'Initial role of macrophage in the development of anti-beta-cell cellular autoimmunity in multiple low-dose streptozotocin-induced diabetes in mice.',1 'Nevertheless, testosterone, a precursor of the prostate growth and differentiation stimulating dehydrotestosterone, was not influenced by CYP3A genotype.',1 'Tacrolimus (100 microg kg(-1), 5 min after splanchnic arteries occlusion) increased survival rate (SAO + Tacrolimus = 100% at 4 h of reperfusion), reverted the marked hypotension, reduced serum TNF-alpha (15+/-3 U ml(-1)), ameliorated leukopenia, reduced ileal MPO (0.9+/-0.01 U g(-1) tissue), restored to control values the hyporeactivity to PE.',1 'CONCLUSIONS : Oxycodone was more potent than morphine for visceral pain relief but not for sedation.',1 'Liposomal daunorubicin at 120 mg/m2 appears to have some activity against refractory lymphoma and we suggest that further studies with this agent are required.',1 'Pseudoprogression after radiotherapy with concurrent temozolomide for high-grade glioma: clinical observations and working recommendations.',1 'To delineate the antigenic determinants on thyroglobulin (Tg) recognized by serum autoantibodies and peripheral blood T cells from patients with chronic thyroiditis, we studied the reactivities of three different Tg preparations, i.e. enzyme-digested Tg fragments, physically or chemically denatured Tg, or Tg with differing iodine contents.',1 'Intracellular calcium signals may regulate the balance of cell survival versus proliferation or anabolic functional response as part of signalling cascades that integrate the response to primary signals via cell stretch, estrogen, tyrosine kinase, and tumor necrosis factor receptors.',1 'Lithium, by modifying the headache course, changes serotonin and histamine levels.',1 'Injection pain of bupivacaine with epinephrine vs. prilocaine plain.',1 'OBJECTIVES : In hepatitis C virus (HCV)-infected patients receiving pegylated interferon (PEG-IFN)/ribavirin (RBV) combination therapy, anemia is a well-known side effect.',1 'DESIGN : Retrospective analysis of a subset of a previously published, prospective, randomized, double-blind, placebo-controlled trial ("Effects of Ibuprofen on the Physiology and Survival of Patients With Sepsis" [ISS]).',1 'Therefore, the objectives of this study were to identify the occurrence of post-transplant diabetes in our clinic population and to characterize the pharmacokinetics of methylprednisolone among our African-American and Caucasian renal transplant recipients.',1 'Proportional hazard analyses adjusted for duration of olanzapine exposure indicated that the first 3 months of olanzapine treatment was associated with an increased risk of diabetes of 90% (95% CI = 40% to 157%, p <.0001), after adjusting for age, gender, and haloperidol use.',1 'CONCLUSION: Low dose diazepam inhibits ventilatory adaptation to mild hypoxia at moderate altitude.',1 'We describe a patient with a defect in the death domain of the FAS molecule who had autoimmune thrombocytopenia resistant to conventional therapy but which responded to a combination of rituximab and vincristine.',1 'It was shown that the ofloxacin-including chemotherapy regimen applied to patients with multiresistant destructive tuberculosis of the lungs provided by the end of the 6-month treatment course elimination of multidrug resistant tubercle bacilli isolation at least in 80% of the patients and closure of the lung caverns after artificial pneumothorax and routine surgical interventions in more than half of the patients.',1 'OBJECTIVE : We tested the null hypothesis that tumor necrosis factor-alpha (TNF-alpha) does not decrease ovulation, estradiol and progesterone production, or prostaglandin (PG) E2, PGF2alpha, or 6 keto-PGF1alpha production in the open bursa rat ovarian perfusion model.',1 'At renal biopsy the histological lesions were identical with those found in ARF due to hyperoxaluria of other causes, revealing tubular epithelial necrosis and massive intratubular precipitation of calcium oxalate monohydrate (C1) crystals.',1 'Warfarin sodium has been associated with leucocytoclastic vasculitis and has once been associated with allergic interstitial nephritis.',1 'Progesterone concentrations were measured daily throughout the cycle corresponding to conceptus removal (or flushing alone) and throughout the preceding cycle.',1 'These data indicate that pregabalin may possess clinical utility as a novel anxiolytic agent and demonstrates the importance of the alpha(2)delta subunit of VDCC in the mediation of anxiety related behaviours.',1 'Milnacipran given either once or twice daily at doses up to 200 mg/day was generally well tolerated and yielded significant improvements relative to placebo on measures of pain, patients global impression of change in their disease state, physical function, and fatigue.',1 'The findings suggest that lidocaine may be more effective than midazolam in reducing or controlling refractory neonatal seizures.',1 'Low testosterone level increases the risk of type-2 diabetes and in diabetics is the testosterone level often low.',1 'The dose of clonidine used to treat the remaining two patients was limited by the development of symptomatic hypotension.',1 'We have compared mechanisms mediating enhanced nociception of four established models of neuropathic pain produced by very different types of insults to the peripheral nervous system: streptozotocin-induced hyperalgesia, a model of diabetic (metabolic) peripheral neuropathy, vincristine-induced hyperalgesia, a model of chemotherapeutic agent (toxic) peripheral neuropathy, and chronic constriction injury and partial nerve ligation, models of trauma-induced painful neuropathies.',1 'The present study supports the role of brain NO in the development of sensitization to both psychostimulants, cocaine and METH.',1 'Posthemorrhage fed animals had high levels of insulin, glucagon, and epinephrine during hemorrhage, whereas insulin levels remained low in food-deprived rats despite exogenously induced hyperglycemia.',1 'The patients had cardinal signs of atropine poisoning, viz., psychosis with hallucinations, tachycardia, fixed dilated pupils and a dry mouth.',1 'In this study, we test the extent to which analgesic effects of acute anger arousal on subsequent pain sensitivity are opioid mediated by subjecting healthy participants to anger-induction and pain either under opioid blockade (oral naltrexone) or placebo.',1 'Furthermore, in mice with hepatic neoplastic nodules of colon adenocarcinoma 26, ME2303 also showed a marked antitumour effect compared to pirarubicin or doxorubicin.',1 'Recurrent bilateral leg ulcers developed in two patients receiving hydroxyurea therapy during the chronic phase of chronic myelogenous leukemia.',1 'Incidence of osteonecrosis of the jaw in women with postmenopausal osteoporosis in the health outcomes and reduced incidence with zoledronic acid once yearly pivotal fracture trial.',1 'This open study evaluated the acute electrophysiologic effects, antiarrhythmic efficacy, and safety of different doses of intravenous dofetilide, a new class III drug, in 50 patients with sustained monomorphic ventricular tachycardia inducible by programmed electrical stimulation who had previously been unsuccessfully treated with 0 to 7 (median 3) other drugs.',1 'METHODS : Fifty-one hypertensive patients with coronary artery stenosis but without coronary artery spasm, treated with a sirolimus-eluting stent, were randomly assigned to either the telmisartan (25 cases) or amlodipine (26 cases) treatment groups.',1 'The skin lesions and pruritus cleared quickly after the administration of cetirizine hydrochloride.',1 'The present study investigated whether a novel -1438G/A polymorphism in the promoter region of the 5-HT(2A )receptor gene is associated with therapeutic response to fluvoxamine (an SSRI) in 66 Japanese patients with major depressive disorder.',1 'Patient age, volume of resection, extent of axillary surgery, a history of diabetes or hypertension, and the use of tamoxifen were not found to be significantly associated with cosmetic outcome or late normal tissue complications.',1 'PURPOSE : To report a massive vitreous hemorrhage in a 26-year-old woman that occurred approximately 6 weeks after she received a ganciclovir implant.',1 'The results also revealed that doxepin had excellent anticonvulsant activity against maximal electroshock-induced seizures in mice with a median effect value (ED(50)) of 6.6 mg/kg.',1 'Topiramate improves psychopathological symptoms and quality of life in women with borderline personality disorder.',1 'Is there a perioperative circulatory side effect of intracameral epinephrine in hypertensive patients undergoing phacoemulsification?',1 'Topiramate-induced weight loss: a review.',1 'Our review of statin-antimicrobial drug interactions suggests that fusidic acid is another CYP450 3A4 enzyme inhibitor with the potential to cause rhabdomyolysis when co-prescribed with simvastatin and atorvastatin.',1 'Recurrent HCV infection reduces the requirement for tacrolimus after liver transplantation.',1 'Cutaneous fibrosis induced by docetaxel: a case report.',1 'The addition of dexamethasone to antibiotic treatment did not provide a therapeutic benefit over antibiotics alone and appeared to reduce the antibiotic efficacy of vancomycin 6 hours after infection.',1 'Thrombin inhibitors in unstable angina: rebound or continuation of angina after argatroban withdrawal?',1 'Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes.',1 'It is likely that nearly all were caused by the use of prednisone for immunosuppression.',1 'The Olanzapine cohort was significantly improved compared to the Other cohort on the scales for depression and anxiety and did not experience the deterioration in physical functioning seen in the Other cohort.',1 'Can we use Tramadol as an anti-shivering agent?',1 'CONCLUSIONS : Modafinil may be useful in controlling cancer-related fatigue in patients who present with severe fatigue but is not useful in patients with mild or moderate fatigue.',1 'Cyclophosphamide and corticosteroids were independently associated with significantly higher risk of major infection (p<0.05 and <0.001, respectively).',1 'One full-term newborn infant and 2 premature ones were treated with cefotaxime for the treatment of suspected sepsis and umbilical suppurative inflammation.',1 'To evaluate the effectiveness and safety of gabapentin in the prophylactic treatment of migraine.',1 'Well-known side effects of cisplatin (nausea, vomiting, nephrotoxicity, myelosuppression) can be managed with preventive methods.',1 'Sixty women were divided into high- (n = 21) and low-vomit (n = 39) groups based on vomiting exposure across all pregnancies and were screened for genetic variation in taste with bitterness of saturated 6-n-propylthiouracil (PROP) delivered on filter paper.',1 'Diuretic potency of combined hydrochlorothiazide and furosemide therapy in patients with azotemia.',1 'Fifty-three ambulatory women with the AIDS wasting syndrome defined as weight less than 90% of ideal body weight or weight loss of more than 10% of the preillness maximum, free of new opportunistic infection within 6 weeks of study initiation, and with screening serum levels of free testosterone less than the mean of the normal reference range (< 3 pg/mL) were enrolled in the study.',1 'Simple schemes including hydration protocols for prevention of CIN, medication for prophylaxis of iodine-induced thyrotoxicosis with thyreostatics and anaphylactoid reactions with histamine antagonists and corticosteroids are suggested.',1 'Heparin-induced thrombocytopenia is an immune-mediated syndrome that results from unfractionated heparin or low molecular weight heparin exposure.',1 'During a period in which she had been taking DL-norgesgrel .25 mg and ethinyl estradiol .05 mg the erythema nodosum was found to be resistant to cessation of OC therapy and to treatment.',1 'Monocationic derivatives of phenylcyclohexyl, being the selective channel blockers of NMDA glutamate receptors, as well memantine and MK-801 in micromolar concentrations, prevented both clonic and tonic components of corazol-induced convulsions.',1 'Retinoic acid has been previously shown to inhibit reactivation of EBV infection.',1 'Skin elasticity of patients with eyelid atopic dermatitis improved significantly to 37.5 +/- 6.3% after treatment with tacrolimus ointment.',1 'The action of isosorbide dinitrate (ISDN) and diltiazem on coronary artery diameter, vascular resistance, and coronary blood flow was determined in instrumented postoperative conscious dogs.',1 'Pretreatment with SCH 23390 (20 mg/kg), a dopamine DA1 antagonist, selectively attenuated the diuresis and natriuresis induced by high doses of diltiazem (100 mg/kg) and nitrendipine (10 mg/kg) without blocking the renal responses to hydrochlorothiazide (1 mg/kg).',1 'Hyperinsulinemia is not a cause of cortisol-induced hypertension.',1 'Ophthalmic fluorometholone-gentamicin was as effective as ophthalmic betamethasone-gentamicin in the control of ocular inflammation after cataract surgery.',1 'Anaphylaxis, immediate and accelerated reactions, atopy, older age and chronic/recurrent urticaria were risk factors for hypersensitivity and/or cross-reactivity between ASA, ibuprofen and paracetamol.',1 'Acute interstitial nephritis and acute renal failure associated with cimetidine therapy.',1 'RESULTS : After correcting the FI of MitoSOX and hydroxyphenyl fluorescein, they showed no change during ischemia, whereas the raw data showed the increase.',1 'Amoxapine overdose. Coma and seizures without cardiotoxic effects.',1 'In the first set, lidocaine or artificial cerebrospinal fluid (ACSF) was microinjected into the POAH of rats at the time of hemorrhage.',1 'Single-agent lenalidomide induces complete remission of acute myeloid leukemia in patients with isolated trisomy 13.',1 'Diethylcarbamazine, a leukotriene synthesis inhibitor, prevented the slow pressure rise and edema seen after indomethacin plus arachidonate.',1 'Angiographic findings in patients exhibiting ischemia after oral dipyridamole.',1 'OBJECTIVE : To investigate the effect of H(2) receptor antagonist cimetidine on the development of immune-mediated aplastic anemia (AA) in mice.',1 'Hitlers neurological pathography is further analysed in respect to an abuse with "Antigas pills" and to some statements in the literature presuming an amphetamine-dependence, a syphilitic manifestation, an epileptic seizure in 1932, and a tremor already present in 1923.',1 'Injection of testosterone in adult rats induced a transient increase of the ventral lobe weight and the specific activity of prostatic VEGF, leading to a 7-fold increase in the prostate content of VEGF.',1 'We measured plasma and platelet magnesium concentrations, plasma epinephrine and norepinephrine, and plasma aldosterone and renin concentrations in normotensive (NT-Ob, n = 19, BMI 35.7 +/- 7.4 kg/m2, WHR 0.92 +/- 0.05) and hypertensive (HT-Ob, n = 11, BMI 35.2 +/- 3.6 kg/m2, WHR 0.93 +/- 0.07) obese subjects, and in a group of age- and sex-matched lean controls (n = 14, BMI 23.1 +/- 1.8 kg/m2, WHR 0.79 +/- 0.05).',1 'Adverse reactions during methotrexate therapy included nausea (5/16) and transaminase elevation (4/16).',1 'These results suggest that increasing dopamine release by administration of amphetamine exacerbates reserpine-induced oral dyskinesia, whereas decreasing the amount of releasable dopamine in the striatum by 6-hydroxydopamine lesions attenuates reserpine-induced oral dyskinsia.',1 'Penicillin anaphylaxis; case report.',1 'In 14-18% of amiodarone-treated patients, there is overt thyroid dysfunction (hypothyroidism or thyrotoxicosis).',1 'We examined the role of diabetes duration on endothelin- plasma levels and vasoconstrictor responses to endothelin-1 in aortic rings from streptozotocin-induced diabetic rats.',1 'Does prolonged warfarin exposure potentiate coronary calcification in humans? Results of the warfarin and coronary calcification study.',1 'The results show that docetaxel is an effective anticancer agent for advanced/recurrent gastric cancer.',1 'CONCLUSION : Sufentanil 0.3 micro g kg-1 is an effective and safe drug to reduce myoclonus after etomidate without causing any harmful side-effect.',1 'Sixteen patients with multifocal atrial tachycardia (MAT) who were taking theophylline were identified over 6 months.',1 'The effects of dexamethasone (DEX) and N omega-nitro-L-arginine methyl ester (L-NAME) on the tumour necrosis factor-alpha (TNF-alpha)-induced increase in permeability of human umbilical vein endothelial cell (HUVEC) monolayer to [125I] labelled bovine serum albumin (BSA) were examined.',1 'Extrapyramidal symptoms during long-term treatment with antipsychotics: special focus on clozapine and D1 and D2 dopamine antagonists.',1 'Serum sickness-like reaction with bupropion.',1 'BACKGROUND : Approximately 40% to 50% of patients with chronic idiopathic urticaria (CIU) have functional IgG autoantibodies against FcepsilonRIalpha or IgE, which induce histamine release from basophils and cutaneous mast cells.',1 'PURPOSE : It has been suggested that age is associated with chemotherapy-related death in patients with non-Hodgkins lymphoma (NHL) treated with doxorubicin-containing chemotherapy.',1 '[Pulmonary fibrosis caused by nitrofurantoin].',1 'Epsilon-aminocaproic acid myopathy. Report of a case and literature review.',1 'PURPOSE : To investigate if antituberculosis medication including ethambutol could be a possible epigenetic factor in visual loss in Lebers hereditary optic neuropathy (LHON).',1 'Systemic L-carnitine deficiencies are usually the result of a variety of disease states including deficient intake in premature infants or long-term parenteral nutrition; renal failure; organic acidemias; and Reyes syndrome.',1 'The potential risk for dehydration associated with lithium-induced polyuria, as well as the discomfort inherent to this side effect, deserves evaluation and consideration for therapeutic intervention.',1 'We concluded that although dissociation accompanied by anxiety was associated with heightened noradrenergic tone, there was a marked basal norepinephrine decline with increasing severity of dissociation.',1 'However, the pathophysiologic significance of dobutamine-induced chest pain is uncertain.',1 'Treatment of patients with D-penicillamine (D-P) has been associated with a syndrome similar to myasthenia gravis (MG).',1 'We examined the possibility of continuing oxazaphosphorine therapy in patients with previously documented cyclophosphamide- or ifosfamide-induced hematuria by concomitant use of the uroprotective agent, mesna.',1 'A single 10-, 20- or 40-micrograms/kg dose of granisetron is comparably effective in controlling nausea and vomiting associated with moderate or high-dose cisplatin chemotherapy.',1 'Two patients experienced fever after pamidronate but no significant toxicity was observed with either treatment.',1 'Patients should be counseled to take tetracycline antibiotics in an upright position with a large amount of fluid and to report esophagitis symptoms to the prescribing physician.',1 '[Three advanced gastric cancer patients successfully treated by combination therapy of docetaxel and TS-1].',1 'Ketamine may have at least theoretical advantages over pethidine as regard respiratory depression, nausea, and vomiting.',1 'The ten stories told here deal with (i) ribavirin as an inhibitor of IMP dehydrogenase and (ii) ribavirin, in combination with pegylated interferon, as the present "standard of care" for hepatitis C; (iii) S-adenosylhomocysteine hydrolase inhibitors as antiviral agents; (iv) new adamantadine derivatives for the treatment of influenza A virus infections; (v) 5-substituted 2-deoxyuridines (i.e. IDU, TFT) for the treatment of herpes simplex virus (HSV) infections; (vi) acyclic guanosine analogues (e.g. acyclovir) for the treatment of HSV infections; (vii) OMP decarboxylase inhibitors (i.e. pyrazofurin) and CTP synthetase inhibitors (i.e. cyclopentenylcytosine) as possible antiviral agents; (viii) the future of cidofovir (and alkoxyalkyl esters thereof) and ST-246 as potential antipoxvirus agents; (ix) the two decade journey from tivirapine to rilpivirine in the ultimate therapy of HIV infections; and (x) the extension of the therapeutic application of tenofovir disoproxil fumarate (Viread) to the treatment of hepatitis B virus infection, in addition to HIV infection.',1 'The induction of physical dependence to morphine in the rat using a subcutaneously implanted reservoir.',1 'The non-selective NMDA receptor antagonist dizocilpine has been shown to suppress not only physical but also psychological dependence produced by morphine.',1 'Mirtazapine associated with profound hyponatremia: two case reports.',1 'Sensitization does not develop to cocaine-induced potentiation of the antinociceptive effect of morphine.',1 'The objective of this study was to characterize peptidergic changes in the streptozotocin-induced diabetes mellitus rat model both quantitatively and qualitatively.',1 'If the period of ischemia is long enough, restoration of the circulation may exacerbate cellular damage, due in part to washout of adenine nucleotide precursor, free-radical-mediated injury and finally calcium-dependent necrosis.',1 'Therapeutics. Review: metformin does not increase risk for lactic acidosis in type 2 diabetes.',1 'Incidence of thrombocytopenia following coronary stent placement using abciximab plus clopidogrel or ticlopidine.',1 'Recent in vitro and in vivo studies suggest that the calcium-sensing receptor (CaR) plays a role in the process of vascular calcification.',1 'Initial studies have shown that renal vascular resistance was reduced in patients with hypertension receiving candesartan, and urinary albumin excretion was reduced in patients with type 2 diabetes mellitus and concomitant microalbuminuria or proteinuria.',1 'Patients in the testosterone group responded with reduction in ascites and pedal edema together with a subjective feeling of improvement.',1 'Danazol, idiopathic thrombocytopenic purpura, and thrombopoietin.',1 '[Nodal rhythm after administration of atropine to bradycardic patients under subarachnoid anesthesia. Four cases and a review of pathophysiology and treatment].',1 'Photosensitivity reaction treated with diphenhydramine.',1 'Results showed significant correlations between testosterone and menstrual irregularities, even when women with the most irregular cycles were excluded from analyses.',1 'Hypotension, as consequence of the interaction between tacrolimus and mirtazapine, in a patient with renal transplant.',1 'The results showed that risperidone and haloperidone were both effective for treating hyperactive symptoms of delirium.',1 '[Thyroglobulin and lithium: apropos of a case of hyperthyroglobulinemia and of goiter following prolonged use of lithium].',1 'To evaluate the effect of controlled-release oxycodone on the relief of dyspnea, we investigated three cases with opioid substitution from subcutaneous morphine to oral oxycodone.',1 'Effect of propofol and alfaxalone on pain after ovariohysterectomy in cats.',1 'BACKGROUND : Our aim was to show the efficacy of naproxen and paracetamol with and without pethidine on pain and nausea and vomiting after adenoidectomy.',1 'OBJECTIVES : We aimed to document our experience with oral clonidine when used as a sedative in combination with intravenous morphine and lorazepam in a group of mechanically ventilated children with single-organ, respiratory failure.',1 'The effects of 6 months of combined hormone therapy with transdermal estradiol (0.05 mg/day x 21 days) and different oral progestogens (10 mg/day medroxyprogesterone acetate [MPA] in the last 12 days, 10 mg/day dihydrogesterone in the last 12 days, and 50 mg/day cyproterone in the first 10 days), on menopausal symptoms and hypothalamo pituitary-ovarian function were studied in normal perimenopausal women.',1 'Pathophysiology and laboratory testing of heparin-induced thrombocytopenia.',1 'Is Lorazepam a treatment for neuroleptic malignant syndrome?',1 'Intrathecal Tyr-W-MIF-1 produces potent, naloxone-reversible analgesia modulated by alpha 2-adrenoceptors.',1 'Increased levels of progesterone in serum have been reported in male patients with essential hypertension (EH).',1 'A 7-day infusion of prostaglandin E1 (PGE1), an immunomodulator, was evaluated in a prospective, randomized, placebo-controlled, double-blinded trial in surgical patients with the adult respiratory distress syndrome (ARDS).',1 'Interventions that reduce spatial inhomogeneities of intracellular calcium may prevent this type of arrhythmia.',1 '[Genetic aspects of individual sensitivity to betaxolol in patients with arterial hypertension].',1 'In spite of a significant antidepressant efficacy of fluoxetine in the two groups, better results were observed in the "agitated-anxious" depressed group: marked improvement on MADRS total score at day 42 (76% decrease vs 62% in the "blunted-retarded" group, p = 0.012), greater number of "responders" defined by a decrease > or = 50% on MADRS total score and a total score < or = 12 (95% vs 63%, p = 0.04), better patients global impression on efficacy (54% of "excellent efficacy" vs 18%, p = 0.012), more improvement on HSCL-58 total score (mean decrease of 69% vs 39%, p = 0.016), higher improvement on "hostility/interpersonal hypersensitivity" score (mean decrease of 74% vs 37%, p = 0.001) and on "anger attacks/irritability" sub-score (mean decrease of 73% vs 30%, p = 0.0002).',1 'Additionally, hyperactivity and reduced anxiety were attenuated by the administration of the mood stabilizer, lithium, but not haloperidol, diazepam, or imipramine.',1 'Discontinuation of docetaxel correlated with resolution of edema and softening of the skin.',1 'High testosterone and low progesterone circulating levels in premenopausal patients with hyperplasia and cancer of the breast.',1 'The diabetes group and diabetes treated group were injected with streptozotocin to induce diabetes.',1 'Autopsy evidence of herpesvirus infection was found in visceral organs of four leukemic patients who had received large doses of cytarabine (cytosine arabinoside; Ara-C) shortly before their death.',1 '[Four additional cases of aplastic anemia following chloramphenicol therapy].',1 'Improvement in health-related quality of life after therapy with omeprazole in patients with coronary artery disease and recurrent angina-like chest pain. A double-blind, placebo-controlled trial of the SF-36 survey.',1 'This report explores the physiological effects of the intravenous alpha-2 agonist xylazine in a canine model of raised ICP after subarachnoid hemorrhage (mean arterial pressure, heart rate, and ICP were measured and compared in five groups: normal saline [n = 4], xylazine [0.05-1.00 mg/kg] [n = 28], tolazoline [a semiselective alpha-2 antagonist, 5 mg/kg] [n = 6], tolazoline [5 mg/kg] plus xylazine [1.0 mg/kg] [n = 7], and phenylephrine [0.008 mg/kg], a selective alpha-1 agonist [n = 3]).',1 'Doxepin (Quitaxon) at doses of 25, 50, and 75 mg was compared with diazepam 7.5, 15, and 22.5 mg, using as variables the percentage lowering of Critical Flicker Fusion (CFF) and the self-estimated degree of drowsiness.',1 'Here, we describe LYG in a 70-year-old renal allograft recipient who, 4 years after transplantation, on tacrolimus and mycophenolate mofetil and prednisone maintenance immunosuppression, complained of low-grade fever, persistent headache and gait disturbance.',1 'Influence of propranolol and pindolol on the haemodynamic effects of papaverine, isoprenaline and noradrenaline in hypertensive patients.',1 'Nifedipine-induced coronary vasodilation in ischemic hearts is attributable to bradykinin- and NO-dependent mechanisms in dogs.',1 'OBJECTIVE : The VERIfy Thrombosis risk ASsessment (VERITAS) was a prospective study designed to measure platelet response to clopidogrel therapy in subjects with multiple risk factors or history of vascular disease using this novel point-of-care assay.',1 'Haemodynamic effects of bromocriptine in the conscious spontaneously hypertensive rat.',1 'Coronary spasm induced by capecitabine mimicks ST elevation myocardial infarction.',1 'Four-year follow-up of imprisoned male heroin users and methadone treatment: mortality, re-incarceration and hepatitis C infection.',1 'On day 12 of amlodipine therapy, the patient developed a pruritic maculopapular rash on her hands for which she sought medical attention.',1 'Hospitalizations because of hypoglycemia in users of animal and human insulins. 2. Experience in the United States.',1 'With the doses used in this study, the repeated administration of tobramycin resulted in blood accumulation only in the group of patients with renal impairment.',1 'Neonatal dexamethasone treatment strongly suppressed body weight gain, and adrenal and thymus weights in the early phase of postnatal development.',1 'The literature suggests that atomoxetine may be associated with suicidal ideation in children.',1 'Among opioid drugs, meperidine can precipitate myoclonus.',1 'The purpose of this study was to evaluate the role of low-dose unfractionated heparin in preventing catheter-related bloodstream infection in patients with hemato-oncological disease.',1 'Direct and reflex bronchoconstriction induced by histamine aerosol inhalation in dogs.',1 'Treatment of Pseudomonas lung infection in cystic fibrosis with piperacillin plus tobramycin versus ceftazidime monotherapy: preliminary communication.',1 'These results support the assumption that colonic hypersensitivity could be normalized by tegaserod acting, at least in part, through peripheral 5-HT(4) receptors.',1 'A great advance was alpha interferon and lamivudine treatment in patients with chronic hepatitis B and alpha interferon treatment along with ribavirine in chronic hepatitis C.',1 'This data suggests that inhibition of NO may be one of the mechanism of morphine induced constipation.',1 'Gastroprotective Effect of Rubia cordifolia Linn. on Aspirin Plus Pylorus-Ligated Ulcer.',1 'On the last day of treatment, a thermistor, connected to a data acquisition system, was placed on the tail of each animal and morphine addiction was withdrawn by naloxone injection (1.0 mg/kg, sc).',1 '[Acute pancreatitis--adverse effect of 5-aminosalicylic acid (mesalazine) in various galenic dosage forms].',1 'The effect on intraocular pressure (IOP) of a 2-week washout following long-term ocular therapy with topical levobunolol or timolol for an average period of 30 months was investigated in 20 patients (11 whites and 9 blacks) with early primary open-angle glaucoma or ocular hypertensive glaucoma suspect status.',1 'The main objective of this retrospective analysis was to evaluate the long-term effect of the heart rate-lowering calcium antagonists verapamil and diltiazem on the incidence of combined cardiac events and all-cause mortality in patients who had experienced a non-Q-wave acute myocardial infarction (AMI), but who did not also have pulmonary congestion.',1 'Myasthenia gravis disclosed by lithium carbonate.',1 'Twelve hours after 100 mg atenolol and 1 gm ampicillin, exercise tachycardia was significantly higher than after atenolol alone.',1 'Intranasal budesonide spray as an adjunct to oral antibiotic therapy for acute sinusitis in children.',1 'Parathyroid hormone-related protein (PTHrP), a factor responsible for malignancy associated hypercalcemia, plays a physiological roles such as bone development and placental calcium transport.',1 'Role of ciprofloxacin in fatal seizures.',1 'Unexpectedly, all primary acute promyelocytic leukemia (APL) samples lacked IRF-1 protein and most exhibited accelerated exon skipping; furthermore, IRF-1 could not be induced by IFNgamma or all-trans retinoic acid (ATRA) which both induce IRF-1 in the NB4 APL cell line.',1 'In conclusion, azithromycin reduces the viability of human bronchial SMCs possibly by leading to apoptotic cell death.',1 '[Lithium salts in the treatment of cluster headache].',1 'Greater levels of endothelin-1 in individuals with decreased FEF(25-75) suggest a response consistent with pulmonary hypertension and/or mild interstitial edema, while epinephrine may be upregulated in these individuals to clear lung fluid through stimulation of β(2)-adrenergic receptors.',1 'This study investigates the IL-8 behaviour in stable angina pectoris after myocardial ischaemia induced by dipyridamole (14 patients) and in unstable angina pectoris, Braunwalds class III (35 patients).',1 'Physicians in areas where Lyme disease has traditionally not been recognized should be alerted to its characteristic rash (erythema chronicum migrans), tick vector (Ixodes species), possible severe manifestations (neurologic, arthritic, and cardiac), and response to appropriate antibiotic therapy (penicillin or tetracycline).',1 'The effect of streptozotocin diabetes on liver protein metabolism.',1 '(4) There were significant increases in intracellular calcium and production of tumor necrosis factor (TNF-alpha) by isolated Kupffer cells stimulated by endotoxin after hemorrhagic shock.',1 'Adverse effects of methotrexate therapy were only regularly observed within the first 2-6 weeks, such as fatigue and transient enhancement of transaminases and serum bile acid concentrations.',1 'Dabigatran is a fixed-dose, oral direct thrombin inhibitor with similar or reduced rates of ischemic stroke and intracranial hemorrhage in patients with AF compared with those of warfarin.',1 'Several muscle relaxants have the potential to promote bronchoconstriction due to unintended effects exemplified by histamine release of atracurium or mivacurium and detrimental interactions with muscarinic receptors by rapacuronium.',1 'Resistant C3H/HeJ mice could be made susceptible to lethal infection by pre-treatment with cyclophosphamide.',1 'Ten of the 16 patients were treated with antimicrobials (mainly metronidazole) and in most cases the diarrhea resolved.',1 '[Prothrombin complex concentrate important in warfarin induced hemorrhage].',1 'Treatment with prednisolone and cyclophosphamide was ineffective against LIP probably because the patient had coexising pulmonary fibrosis.',1 'CONCLUSION : Subcellular organelles and membranes were the structures most protected by allopurinol, indirectly demonstrating their role of main and early target of oxygen-derived free radicals in the pathogenesis of acute pancreatitis.',1 'Morphine induced a pronounced context-dependent sensitization that crossed with cocaine.',1 'Oral etoposide was not well tolerated with grade 4 neutropenia occurring in 33.3% and grade 4 thrombocytopenia occurring in 15%.',1 'However, it may be difficult to use celecoxib for the treatment of heart failure because of thromboembolic adverse reactions.',1 'The median time of late paclitaxel stent thrombosis was 18 months, whereas it was 3.5 months in bare metal stent patients.',1 'Experimental exophthalmos in rats due to thiouracil and cortisone.',1 'Novel mechanisms of the antiproliferative effects of amlodipine in vascular smooth muscle cells from spontaneously hypertensive rats.',1 'Amiodarone hydrochloride, an investigational drug used to suppress ventricular arrhythmias, may cause pulmonary toxicity with associated radiographic abnormalities.',1 'Mild side effects were associated with high peak concentrations of praziquantel, but a syndrome of severe abdominal pain followed by bloody diarrhea was not.',1 'Degree of histamine responsiveness was closer associated with other asthma-related factors, including self-reported asthma, use of asthma medication, and level of lung function, than PEF variability and bronchodilator responsiveness.',1 'OBJECTIVE : To investigate the effects of methylphenidate (MPH) on components of working memory (WM) in children with ADHD and determine whether MPH produces differential effects on WM in children with comorbid anxiety (ANX).',1 'In vitro estrogen biosynthesis from testosterone by homogenates of placentas from normal pregnancies and pregnancies complicated by intrauterine fetal malnutrition and diabetes.',1 'Hypotension or bradycardia within 4 hours of commencing amiodarone were noted in 2 patients.',1 'Laboratory data showed blasts in the peripheral blood, hypercalcemia (corrected calcium 15.1 mg/dl) and an increased level of parathyroid hormone related-protein (PTHrP).',1 'A leg bone pain syndrome of unclear etiology has been recently described in renal transplant patients receiving cyclosporine A. Herein we report a 54-year-old woman treated with cyclosporine A (CsA), corticosteroids and azathioprine who developed two months after renal transplantation severe symmetric pain with periarticular soft tissue swelling in the knees and metatarsophalangeal joints.',1 'Effects of hypoxia on atrioventricular conduction were investigated in the Langendorff-perfused isolated heart of the rabbit with various extracellular calcium concentrations ([Ca2+]) as well as in the presence of verapamil, nifedipine, N-(6-aminohexyl)-5-chloro-1-naphthalenesulphonamide (W-7) and chlorpromazine.',1 'Impact of tacrolimus versus cyclosporine in hepatitis C virus-infected liver transplant recipients on recurrent hepatitis: a prospective, randomized trial.',1 'RESULTS : Of the 78 acetaminophen toxic patients with vomiting, 17/51 patients (33.3%) who received a nonondansetron antiemetic failed therapy and required IV ondansetron.',1 'Exposure to nicotine during pre- and early postnatal development had an anxiogenic effect on adult rats (P75) in the elevated plus maze (EPM), and blocked extinction learning in a fear conditioning paradigm, suggesting that pre- and postnatal nicotine exposure affect anxiety-like behavior and cognitive function well into adulthood.',1 'In a prospective study, patients undergoing abdominal cancer surgery were randomly allocated to receive either general anesthesia with fentanyl intravenously and postoperative analgesia with parenteral morphine (GA group) or general anesthesia combined with epidural bupivacaine and epidural morphine for postoperative pain relief (EP group).',1 'Similarly, treatment of selected hyperuricemic patients who also are hypertensive with losartan or amlodipine may be beneficial in lowering blood pressure and hyperuricemia.',1 'In a double-blind study, thirty patients having mild to moderate essential hypertension were randomly assigned to a six week regimen of either tienilic acid, hydrochlorothiazide, or placebo.',1 'Twenty AIA patients and 23 aspirin-tolerant asthma (ATA) patients were identified.',1 'The beneficial effect of tamoxifen therapy in patients with resected adenocarcinoma of the pancreas.',1 'Anemia is a frequent side effect of ribavirin.',1 'We report a case of bacteremia due to Abiotrophia species in a patient with neutropenic fever and cancer who was receiving levofloxacin prophylaxis, followed by empirical therapy with cefepime; the organism was resistant to both antibiotics.',1 'Although methotrexate has been used in treatment of RP-related necrotizing scleritis with poor results, it can be sufficient for the conjunctivitis with microangiopathy associated with RP.',1 'The role of inhibiting NHE activity in preventing the development of the mesenteric hypertrophy in streptozotocin-diabetic rats was investigated by administration of cariporide (100 mg/kg body weight per day in 3 doses by gavage) after induction of diabetes and subsequently determining vessel weight and structure.',1 'Cabergoline alone at 0.2 mg/kg or less improved in a dose-dependent fashion the parkinsonism without inducing hyperactivity and dyskinesia following a single subcutaneous injection.',1 'As calcium channel antagonists might have a detrimental effect in patients with heart failure, the effect of verapamil on major events in patients with and without impaired left ventricular function was analysed.',1 'The cases demonstrated the vagaries of DIC and both showed decreased overt hemorrhage after heparin treatment was started.',1 'Likewise, NTS microinjections of granisetron, a specific 5-HT3 receptor antagonist, prevented, in a dose-dependent manner, the baroreflex bradycardia inhibition.',1 'Heroin, d-propoxyphene and meperidine produced nonlethal clonic seizures, whereas normeperidine and thebaine produced tonic-clonic seizures which were followed by death.',1 'One of the problems in research on symptom perception during histamine challenge has been the difficulty in finding both a valid and practical parameter of the "perceptiveness" for bronchoconstriction in a subject.',1 'Testosterone concentrations in plasma and in both left and right testis were estimated in both sham-operated and varicocele-induced rats.',1 'The transforming proteins of acute promyelocytic leukaemias (APL) are fusions of the promyelocytic leukaemia (PML) and the promyelocytic leukaemia zinc-finger (PLZF) proteins with retinoic acid receptor-alpha (RARalpha).',1 'Amiodarone for the treatment of persistent atrial fibrillation.',1 '[Congenital chloride diarrhea. Clinical and biological study of a case in a child].',1 'In RA, the decreasing progesterone phase was different from the increasing oestrogen phase for pain (P = 0.06).',1 'When using antimetabolites, the risk factors for failure must be well known and either 5-fluorouracile or mitomycin should be chosen depending on the level of risk of scarring.',1 'Hypersensitivity Reactions to oxaliplatin: incidence and management.',1 'RESULTS : Controlled hypotension was achieved within a shorter period using laryngeal mask using lower rates of remifentanil infusion and lower total dose of remifentanil.',1 'To assess the effects of angiotensin-converting enzyme inhibition with quinapril on blood lipid profile, serum total cholesterol and triglycerides, together with high-density and low-density lipoprotein cholesterol were analysed in 23 hypertensive patients receiving either placebo (7 patients) or quinapril hydrochloride (16 patients).',1 'Diabetes risk was significantly lower among males receiving risperidone (HR = 0.49; p < 0.01) or quetiapine (HR = 0.50; p < 0.10), while diabetes risk among females did not differ significantly from first-generation antipsychotics for any atypical examined.',1 'Indinavir nephrolithiasis in warm climates.',1 'Patients unresponsive to conventional antiepileptics, including those with generalized seizures, may benefit from adjunctive flumazenil therapy.',1 'Compared to unfractionated heparin and coumadin, LMWH has more predictable pharmacokinetics and a reported lower incidence of osteoporosis and heparin-induced thrombocytopenia in children.',1 'Of the ampicillin-treated group, 29% had diarrhea and/or abdominal cramping.',1 'Role of different brain structures in the expression of the physical morphine withdrawal syndrome.',1 'All operative and postoperative outcomes for pain, anxiety, and vomiting were similar in the two groups except for immediate postoperative nausea, which was higher in the propofol infusion group.',1 'Both nefazodone and imipramine exhibited antidepressant efficacy compared with that of placebo, irrespective of baseline anxiety levels.',1 'CONCLUSION : Sildenafil is able to reduce the ascending of ABR thresholds shift, and it can significantly protect against noise-induced hearing loss.',1 'The anammox bacteria were not inhibited by the high NO concentration but rather used it to oxidize additional ammonium to dinitrogen gas under conditions relevant to wastewater treatment.',1 'OBJECTIVE : The objective was to analyze outcome of clozapine therapy in elderly patients with treatment refractory primary psychosis.',1 'But use of diazepam either during or as pretreatment may reduce the fasciculation, after pain and rise of K+ and CPK levels.',1 'Propofol injection pain is not alleviated by pretreatment with flurbiprofen axetil, a prodrug of a nonsteroidal antiinflammatory drug.',1 'Docetaxel or pemetrexed is a more reasonable choice than cisplatin for treatment of NSCLC patients who failed to respond to EGFR-TKI.',1 'Another cause is the syndrome of inappropriate secretion of anti-diuretic hormone, SIADH, which may be due to a number of psychotropic drugs as carbamazepine, thioridazine, amitriptyline, desipramine, haloperidol, chlorpromazine and fluoxetine (1, 2, 7, 9, 15, 18, 24).',1 'D-004 has shown protective effects on prostate hyperplasia induced by testosterone in rodents.',1 'Recent attempts with other anabolic hormones, estradiol and progesterone, have proven remarkably effective in improving the adaptive physiological responses of calves to either E. bovis infection or to the injection of LPS.',1 'Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution.',1 'Docetaxel plus oxaliplatin (DOCOX) as a second-line treatment after failure of fluoropyrimidine and platinum in Chinese patients with advanced gastric cancer.',1 'Amantadine-associated corneal edema.',1 'Parameters that influence the outcome of nausea and emesis in cisplatin based chemotherapy.',1 'A patient subject to malignant hyperthermia does not necessarily develop rigidity after succinylcholine for the intubation as noticed in this case.',1 'We report a woman with hypertensive renal disease who was receiving hemodialysis and developed pancytopenia following a single intradermal infiltration of 25 mg of methotrexate.',1 'Muscle rigidity causing life-threatening hypercapnia following fentanyl administration in a premature infant.',1 'Heart rate was unchanged among treatments immediately before epinephrine-induced arrhythmia.',1 'CASE REPORTS : We report the cases of 2 patients, treated for undifferentiated bronchial carcinoma and carcinoma of the breast, presenting with hypersensitivity reactions to carboplatin developing after 6 and 8 courses respectively.',1 'Hirsutism: free and bound testosterone.',1 'To elucidate the mechanism of SE-induced vasogenic edema, we investigated the roles of tumor necrosis factor (TNF)-α in blood-brain barrier (BBB) disruption during vasogenic edema and its related events in rat epilepsy models provoked by pilocarpine-induced SE.',1 'Fifty mature normoglycaemic male Wistar rats, weighing 200-250 g, were selected and randomly divided into 5 groups (n = 10): control; STZ-induced diabetic (D) - by intraperitoneal injection of 60 mg/kg streptozotocin; treated control (TC); and treated diabetic (TD1, 2), respectively, received 20 and 62.5 g/kg of eucalyptus in their diet, and 2.5 g/L aqueous extract of eucalyptus in their drinking water from one week after induction of diabetes.',1 'Relation between systemic anticoagulation as determined by activated partial thromboplastin time and heparin measurements and in-hospital clinical events in unstable angina and non-Q wave myocardiaL infarction. Thrombolysis in Myocardial Ischemia III B Investigators.',1 'The effect of tumor necrosis factor-alpha and interferon-gamma on L-arginine transport, mRNA expression of cationic amino acid transporter and inducible nitric oxide synthase, and nitric oxide production of stellate cells was assessed.',1 'Actually, the secondary hyperprolactinemia induced by some antipsychotics (typical antipsychotics, risperidone and amisulpiride), is dose-dependent, more pronounced for female patients, and may have a detrimental effect on sexual function.',1 'Effects of remifentanil anesthesia on cardiac electrophysiologic properties in children undergoing catheter ablation of supraventricular tachycardia.',1 'CONCLUSION : Oral quinidine is effective in suppressing the gain of function in IKr responsible for some cases of short QT syndrome with a mutation in HERG and thus restoring normal rate dependence of the QT interval and rendering ventricular tachycardia/ventricular fibrillation noninducible.',1 'The concentrations of theophylline, terbutaline and salbutamol in post-mortem blood samples from 68 patients (17-85 years old) with asthma or chronic obstructive lung disease, 54 of whom had died of asthma, were analysed.',1 'CONCLUSION : A stromal cell defect in endometriosis blocks formation of progesterone-dependent production of factors leading to 17beta-hydroxysteroid dehydrogenase type 2 deficiency and defective conversion of estradiol to estrone in epithelium.',1 '[Grave diabetes with rheumatoid arthritis treated with cortisone].',1 '[Aspirin intolerance in patients with nasal polyps and bronchial asthma].',1 'Forty patients with hematologic malignancy or aplastic anemia were given allogeneic marrow after conditioning with high-dose cyclophosphamide alone or in combination with total body irradiation.',1 'One patient in the N group reported urticaria while no adverse events were reported for K. Both products were cosmetically acceptable with respect to feasibility of application and formulation with a preference for K. Ketomousse (1% ketoconazole) provides an equal efficacy and tolerability compared to ketoconazole cream 2%.',1 'Riluzole does not attenuate increases in hippocampal glutamate concentrations in a rabbit model of repeated transient global cerebral ischemia.',1 'PURPOSE : The nonselective muscarinic antagonist atropine is currently the most potent drug against myopia development in both humans and animal models.',1 'We reported previously the in vitro efficacy of the Herpes Simplex Virus Thymidine kinase (HSV-tk)/ganciclovir (GCV) system to mediate cytotoxicity in oral squamous cancer cells, using transferrin (Tf)-lipoplexes, prepared from cationic liposomes composed of 1,2-dioleoyl-3-(trimethylammonium) propane (DOTAP) and cholesterol.',1 'Because adrenoceptors may down-regulate in response to chronic stimulation, we investigated the activity of alpha 2-receptor-mediated vasoconstriction in patients with congestive heart failure, who had increased levels of plasma norepinephrine.',1 'The aim of the present study was to analyze the activity of bortezomib in glioblastoma cell lines in comparison with that in a pediatric acute lymphoblastic leukemia cell line.',1 'Serum testosterone, dihydrotestosterone, delta 4-androstendione and 17 beta-estradiol, sex hormone binding globulin (SHBG) and gonadotropic response to luteinizing hormone releasing hormone (LHRH) were studied in 34 male subjects with episodic or chronic cluster headache (CH).',1 'VI. Catecholamine metabolism in the brain and adrenal medulla during addiction to morphine and in the early abstinence period.',1 'This dose level of amsacrine caused severe mucositis in 24% of patients and marked liver function abnormalities in 11%.',1 'A series of five consecutive generalized seizures at 48-h intervals caused an increase in bursts in rats with estradiol replacement, but not in rats without estradiol.',1 'OBJECTIVE : To investigate the effects of sildenafil on noradrenaline- and potassium-induced contractions of isolated human seminal vesicles (SVs), as premature ejaculation is a relatively common male sexual dysfunction that currently lacks an adequate therapy, and recent in vitro tests showed that sildenafil induces relaxation of rodent isolated SVs, but it is not known whether it also inhibits isolated human SV.',1 'These results suggest a favorable combination of intrathecal midazolam and clonidine in the management of acute and inflammatory pain after proper neurotoxicologic studies.',1 'Hepatic artery infusion of etoposide was performed without serious complication and the dose limiting toxicity was leukopenia.',1 'Maintenance immunosuppression is triple therapy consisting of a calcineurin inhibitor (cyclosporine or tacrolimus), corticosteroids, and an anti-metabolite such as azathioprine (AZA) or mycophenolate mofetil (MMF).',1 'There are several ways to prevent GvHD: remove donor T cells from the transplant (ex vivo T-cell depletion), administer T-cell antibodies to the patient (in vivo T-cell depletion), administer immunosuppressive drugs such as methotrexate, cyclosporin, tacrolimus, and mycofenolate (post-transplant immunosuppression).',1 'Preclinical vitamin B12 deficiency in vegetarians may be the cause for disturbed remethylation and folate trap.',1 'PURPOSE : To investigate trends in mortality rates due to both myocardial infarction and gastrointestinal haemorrhage before and after rofecoxib withdrawal and the release of regulatory guidance regarding the use of other COX-2 inhibitors.',1 'Six weeks after receiving methimazole for the treatment of hyperthyroidism, she had severe jaundice and itching.',1 'There are no natural animal models of hypercalciuria, such as the spontaneous hypertensive rat; however, the streptozotocin-diabetic rat is accepted as a good model for studies of disordered renal function associated with diabetes mellitus.',1 'Colchicine therapy was initiated and her episodes with abdominal pain and fever became less frequent.',1 'These results implicate 17beta-estradiol as a potential target that can readily be modulated to prevent segmental pain following SCI.',1 'Improvement of quality of life in panic disorder with escitalopram, citalopram, or placebo.',1 'The antihypertensive effects of oral treatment with valsartan were preclinically demonstrated in the sodium-depleted marmosets, renal hypertensive rats (2K1C), spontaneous hypertensive rats (SHR) and stroke-prone SHR.',1 'Seven non-splenectomized patients with chronic refractory idiopathic thrombocytopenic purpura were treated with danazol 800 mg daily.',1 'METHODS : Over a period of 8 weeks, the effect of seven constant doses of an ARB, valsartan (4-160 mg/kg per day), on blood pressure and proteinuria taken as a surrogate marker of nephropathy in a hypertensive, type 2 diabetic rat model, the spontaneously hypertensive/NIH-corpulent rat (SHR/NDmcr-cp), was assessed.',1 'Amphetamine-induced twitching of the suprahyoid muscle in nialamide-pretreated, urethane-anaesthetised rats was inhibited by the benzodiazepine agonists RU 32007, diazepam and chlordiazepoxide and the GABAA agonist muscimol.',1 'Continuous subcutaneous buprenorphine administration via a portable infusion pump allows patients with severe pain from cancer the opportunity to move about freely.',1 'Effect of prostaglandin E1-induced hypotension on carbon dioxide reactivity and local cerebral blood flow after subarachnoid haemorrhage.',1 'A 6-year-old boy receiving carbamazepine for partial seizure disorder developed hepatorenal failure.',1 'Reversible leucopenia or thrombocytopenia was reported in seven patients on ticlopidine.',1 'Prophylactic trimethoprim-sulfamethoxazole (TMP-SMZ) has been shown to reduce the incidence of fever, parenteral antibiotic usage, and infections with gram-negative bacteria in hospitalized patients with neutropenia.',1 'We report a case of hypotension and syncope during dobutamine stress echocardiography in which a severe intraventricular gradient of over 200 mmHg and systolic anterior movement of the mitral valve were observed.',1 'In other groups, the early withdrawals were treated with alphaxalone, diazepam, PK11159, or flumazenil to block anxiety-like behavior during an untreated later (third) withdrawal.',1 'Here, we report a 63-year-old patient with overt hypothyroidism that developed due to habitual gargling with povidone iodine for more than 10 years.',1 '[3 cases of suspected adverse effects after high doses of bumetanide in patients with renal failure].',1 'Letter: Quinidine and granulomatous hepatitis.',1 'The objective of this study was to determine the prevalence of ocular hemorrhage in patients receiving warfarin and to compare it to the prevalence in the general population.',1 'The phase II clinical trials with dextromethorphan/quinidine for the treatment of neuropathic pain have been completed.',1 'Effective treatment of bulimia with fluoxetine, a serotonin reuptake inhibitor, in a patient with type I diabetes mellitus.',1 'Tolerance to and physical dependence on morphine in the rat was induced by injecting increasing doses of morphine sulfate (M.S.) administered i.p. twice daily for 14 days.',1 'CONCLUSIONS : High-dose ITOs combined with a postoperative IV naloxone infusion provided excellent analgesia for major pelvic surgery.',1 'This study was undertaken to evaluate the efficacy of granisetron/dexamethasone combination for preventing postoperative nausea and vomiting (PONV) after lapIaroscopic cholecystectomy (LC).',1 'The MACE was associated with a larger extent of WMA (8 +/- 4 segments vs. 5 +/- 3 segments, p < 0.001), WMA-dobutamine (6 +/- 4 segments vs. 4 +/- 3 segments, p = 0.004), microvascular obstruction (3 +/- 3 segments vs. 1 +/- 2 segments p <0.001), and transmural necrosis (7 +/- 3 segments vs. 3 +/- 3 segments, p < 0.001).',1 'These data indicate that topotecan can be safely administered to patients with pleural effusions or ascites and that there is substantial penetration of topotecan into these third spaces, which may prove beneficial for local antitumor effects.',1 'We describe a case of reversible encephalopathy caused by the recently released anticancer drug Ifosfamide.',1 'CASE SUMMARY : A 50-year-old Caucasian man developed an elevated carbamazapine level after starting terbinafine, which caused symptoms of toxicity with gait ataxia, dizziness and falls.',1 'Changes in lipid and lipoprotein values during a cross-over treatment of doxazosin, moduretic and amlodipine in hypertensive patients.',1 'Nephrotic syndrome caused by the angiogenesis inhibitor sorafenib.',1 'OBJECTIVE : The specific aim of this study was to quantify at term the influence of postnatal systemic dexamethasone treatment for neonatal chronic lung disease on subsequent brain growth and development in premature infants without evidence of severe intraventricular hemorrhage or white matter injury.',1 'This present study was designed to examine (1) whether a combination therapy of TNF (tumor necrosis factor) blockers and methotrexate (MTX) is better than MTX monotherapy, and (2) if the TNF inhibitors such as etanercept, infliximab and adalimumab are all same for treating patients with active rheumatoid arthritis (RA).',1 'We conclude that intrathecal midazolam is an effective treatment for chronic mechanical low back pain.',1 'None of the topical calcineurin inhibitors have been associated with systemic immunosuppression-related malignancies known to occur following long-term sustained systemic immunosuppression with oral immunosuppressants (e.g., tacrolimus, cyclosporine A, and corticosteroids) in transplant patients.',1 'METHOD : One hundred sixty-one patients completed fatigue questionnaires and provided salivary cortisol samples before undergoing an elective inpatient surgical procedure, and then 2 days, 3 weeks, and 6 months afterward.',1 'Double-blind trial of alprazolam and chlordiazepoxide in the management of the acute ethanol withdrawal syndrome.',1 'Influence of linezolid clearance on the induction of thrombocytopenia and reduction of hemoglobin.',1 'The P-450 inhibitors 8-methoxypsoralen, piperonyl butoxide, and cimetidine markedly decreased lung edema from transvascular fluid flux.',1 'Cardiorespiratory and behavioral reactions to the lidocaine-induced convulsions in the dog.',1 '[Late postoperative amiodarone pulmonary toxicity].',1 'This study examined nicotine replacement effects and pre-quit smoking characteristics with respect to post-cessation weight gain in a primarily Mexican-American sample of Hispanic smokers.',1 'The effects of selective blockade of alpha2- or I1 receptor by 2-methoxyidazoxan and efaroxan, respectively, on the blood pressure and heart rate responses to clonidine and subsequent ethanol administration were evaluated in conscious spontaneously hypertensive rats.',1 'Using a rat heart model of cardiopulmonary bypass and ischemic cardiac arrest, we have found magnesium to be a highly effective component of protective infusates which can be additive to hypothermia and other protective agents.',1 'We report the first pediatric case of successful orthotopic liver transplantation for disulfiram-induced fulminant hepatic failure in a 16-year-old girl, who developed an idiosyncratic reaction associated with short-term, low-dose disulfiram use, as evidenced by her liver biopsy and explanted liver.',1 'Comparison of efficacy of mometasone furoate versus clarithromycin in the treatment of chronic rhinosinusitis without nasal polyps in Chinese adults.',1 'The impact of the opioids fentanyl and morphine on nociception and bone destruction in a murine model of bone cancer pain.',1 'Thus, contrary to myasthenia and idiopathic autoimmune haemolytic anaemia, we never found autoantibodies specifically directed against the thyroid, the stomach or the adrenal gland during treatment with D-penicillamine and alpha-methyldopa.',1 'Effects of pretreatment with vitamin D, parathyroid hormone or calcium preparation of the calcification of dentine, serum calcium and other blood and urinary constituents of the rabbit.',1 'By demonstrating that CR-oxycodone is safe, generally adequately tolerated, and appears to have efficacy for relieving acute pain, the results of this clinical trial provide a foundation for evidence-based treatment for acute pain in herpes zoster.',1 '[Report of two cases with pleural effusion and ascites that responded dramatically to the combination of thalidomide, celecoxib, irinotecan, and CDDP infused in thoracic and abdominal cavities].',1 'For some patients, the main challenges to use of carbamazepine may be common drug-drug interactions and increased side effects related to aggressive introduction during treatment of acute manic and mixed episodes.',1 'In the three cases, the administration of intravenous lacosamide has led to a considerable improvement in pain.',1 'CONCLUSIONS : Continuous intrathecal infusion of bupivacaine, with or without buprenorphine, appeared to be an effective method for the long-term treatment (months to > 1 year) of "refractory" pain from vertebral compression fractures, in this small group of patients.',1 'Calcium supplement use has increased and there is confusion about the relative absorbability of various sources.',1 'RESULTS : Nausea or vomiting ascribable to the subcutaneous morphine developed in 40% of the patients in each group (P:NS).',1 'Esomeprazole with aspirin versus clopidogrel for prevention of recurrent gastrointestinal ulcer complications.',1 'In comparison to these NK1 and NK2 antagonists, the mu-opioid agonists (morphine and fentanyl) and kappa-opioid agonists (enadoline and U 69,593) equipotently inhibited all nociceptive responses at doses not provoking ataxia.',1 'Females on olanzapine (14%) or quetiapine (8%) experienced a lower rate of menstrual irregularities, compared to females on risperidone (23%) or haloperidol (29%).',1 'Thus, piroxicam, 20 mg daily, matches indomethacin, 25 mg t.i.d., in the treatment of low back pain.',1 'Improved outcome of elderly patients (> or = 75 years of age) with acute myocardial infarction from 1981-1983 to 1992-1994 in Israel. The SPRINT and Thrombolytic Survey Groups. Secondary Prevention Reinfarction Israel Nifedipine Trial.',1 'The authors report one case of pituitary abscess; the diagnosis of which was particularly difficult due to its association to a multiple sclerosis that began twelve years before.',0 'The absolute amount of nitrogen immobilized increased in proportion to the quantity of nitrogen added, but the relative immobilization tended to decrease with the increased inorganic nitrogen the soil.',0 'Induction of expression of RTA was lethal.',0 'It is concluded that (i) 11-CH3CPP-17-one is an inducer of the CYP1 family; (ii) under the present experimental conditions only the CYP1 family can oxidise the A-ring to form the 3,4-dihydroxy-11-CH3-CPP-17-one, the precursor of the ultimate carcinogen and (iii) only the CYP1 family oxidizes the diol to generate the ultimate carcinogen.',0 'The patients were then divided into two groups.',0 'Epidemiology of cancer: current perspectives.',0 'After 4 days of repeated daily immobilization (2.5 hours/day), the secretory response of beta-endorphin/lipotropin was similar to that on day 1, but NK activity was lower than on day 1.',0 'A two-pass adaptive filtering algorithm is proposed for cancellation of recurrent interferences such as the heart interference in biomedical signals.',0 'The severity of the manifestations of CHD at baseline investigation appeared to be a powerful predictor of sudden coronary death.',0 'Complications included colon perforations, colonic bleeding, small-bowel infarction, pancreatitis, subphrenic abscess, and upper GI tract bleeding.',0 'IRRC approves long-term care regulations.',0 'Hemodynamic studies revealed elevation of biventricular filling pressures in 3 of 10 animals; as a group, infected animals manifested significantly elevated right ventricular filling pressures.',0 'Insertion of the 3 UTR of ODC downstream of the translation termination codon of the reporter gene but prior to the polyadenylation signal partially relieves the suppression of translation imposed by the 5 UTR; the overall translatability of the message improves 30-50-fold.',0 'Of the 49 patients that had not undergone splenectomy, 47 had splenic enlargement.',0 'Fluvoxamine--a baseline study of clinical response, long term tolerance and safety in a general practice population.',0 'It is suggested that the increased discharge rate of muscle endings during co-contraction is caused either by small changes in the length of the TA muscle or by a disproportionately high fusimotor drive during co-contraction.',0 'The regulation of neurofilament protein dynamics by phosphorylation: clues to neurofibrillary pathobiology.',0 'Fifty patients suffering from the late effects of urinary bilharziasis were studied.',0 'A novel gene from the nematode Caenorhabditis elegans was isolated by hybridization with a human calmodulin complementary DNA probe.',0 '[The immediate and remote results of surgical treatment of renal adenocarcinomas. Discussion of two hundred and twenty-two cases (authors transl)].',0 'The %fractional shortening (%FS), mean Vcf (mVcf) and ejection fraction (EF) were obtained as left ventricular systolic function by echocardiogram.',0 'The experimental group showed significant improvement over the control group in flexibility, strength and endurance during the school year; part of that improvement was maintained over the summer months; the physical fitness program had a positive influence on the general activity level of the students and was adopted by nine of the other 10 classrooms in the experimental school.',0 'The wife was present when treatment was stopped and the patient was pronounced dead.',0 'Eight older men (72 yr) completed 6 months of aerobic cycle training.',0 'Monocyte IgG-Fc receptors in myotonic dystrophy.',0 'Suspected thrombasthenia in a shetland sheepdog.',0 'Various purines were investigated with the Desaga Resomat II, their diffusion speed constants calculated according to Stricker and compared with one another.',0 'The role of lysosome in cellular physiology and pathology has drawn considerable recent attention by several groups of investigators.',0 'These results in pigs are compared with the reported results in humans.',0 'Women had higher values than men.',0 'However, in several cases the repeated and exclusive usage of this insecticide caused a quick development to highly resistant populations.',0 '264:21481), indicate that the repertoire of VL and VH gene segments used by anti-MAG IgM is quite diverse, in contrast to previous structural data obtained for other human monoclonal IgM autoantibodies.',0 'The treatment of the syndrome of chronic inappropriate antidiuretic hormone (ADH) secretion by fluid restriction is often attended by poor patient compliance.',0 'The data indicate that PGA effectively restores synaptic plasticity after both prenatal and acute exposure to ethanol and suggest that impaired LTP may be a useful model for studying the mechanisms of action of nootropic compounds.',0 'Cholangitis is the most frequent in both categories.',0 'The 5-year actuarial survival and disease-free survival were 64% and 61%, respectively.',0 'Anticoagulant in cerebrovascular disease.',0 'Genetic engineering in South Africa.',0 'Thalassemic patients showed more auditory impairment than controls, an higher incidence of tonsillar hypertrophy, adenotonsillitis and submandibular lymph-node enlargement.',0 'The rate of DNA degradation was similar during a 30-40 min period after UV during which the bulk of dimers was excised.',0 'Syndrome of absent abdominal muscles: two cases with microcephaly, polymicrogyria, and cerebellar malformations.',0 'Colposcopically directed punch biopsy specimens were taken from normal cervix and from histologically proved cervical intraepithelial neoplasia for immunohistochemical studies.',0 'Expression and modulation of common acute lymphoblastic leukaemia antigen by B prolymphocytic leukaemia cells.',0 'The most studied treatment so far has been clomipramine, which appeared superior to placebo and to other antidepressant drugs (amitriptyline, imipramine, desipramine and clorgyline) in a large number of independent controlled studies.',0 'The early complications of bone marrow transplantation.',0 'Demographic data, clinical stage of ALS, illness experience, wishes for information, and desires for participating in decisions about life-sustaining therapy were elicited.',0 'Mean +/- S.D. unadjusted medication costs per occupied bed were $6744 +/- $3048 and varied significantly with geographic region.',0 'At processing, about 30% of the turkeys were still colonized with strain 115.',0 'Quantitative determinations of two decongestants and an antihistamine in combination using paired ion high-pressure liquid chromatography.',0 'The extent of this reaction exhibits genetic polymorphism, with 2 phenotypes, "poor metabolizers" and "extensive metabolizers," discernible in the normal population.',0 'A total of 46 patients were admitted to Mpilo Central Hospital for various reconstructive procedures between August 1988 and February 1989.',0 'This diet contained 0.7 g Ca and 2.1 g P per day.',0 'Nine site-specific single and double mutants were generated using oligonucleotide-directed mutagenesis in an M13 expression vector encoding the L6 Fab.',0 'We suggest that these varicosities derive from a presumably glycinergic interplexiform cell.',0 'Lipid bilayer-based sensors and biomolecular electronics.',0 'Adrenocortical sensitivity to ACTH in humans.',0 'Oral administration of salicylate (50 mg/kg), aspirin (50 mg/kg), and indomethacin (3.5 mg/kg) significantly increased ulcerogenesis over the basal value by six- to sevenfold, but ibuprofens (10 mg/kg) fourfold increase was not significant.',0 'As the hole size is increased from 7/64" to 5/32", the release rate increases and the release time is shortened.',0 'Spectrophotometric determination of bromopyruvate by reaction with 2-nitro-5-thiobenzoic acid.',0 'Yamakis index of pulmonary vascular disease, though effective in describing severity of plexogenic arteriopathy, proved to be less so for the intimal lesions in old microthrombi and for musculoelastosis.',0 'Arrhenius analysis revealed a biphasic curve for lysine uptake with transition temperature (Tc) around 20 degrees C (24 degrees C at pH 5.2 in presence of Na+).',0 'Comparative nutrition of cats and dogs.',0 'No correlation was found between CBF and MEA or fibrinogen in the subjects under the age of 45.',0 'The uptake of different, radioactively labeled nanoparticles (NP) made of polyalkylcyanoacrylate, polymethylmethacrylate (PMMA), and human serum albumin (HSA) by the macrophages was determined.',0 'Video tape recordings of finger movements by ten students reading prose text were subjected to frame by frame analyses of synchronous finger positions.',0 'Higher concentrations lead to cytotoxicity.',0 'A direct correlation was found between the initial rate of incorporation of [14C]thymidine into DNA and the maximum growth rate of the hepatomas and regenerating liver.',0 'Fetal heart rate and amniotic fluid testing were of value while urinary estriols failed to be useful in management or timing of delivery.',0 'Quantitative electromyography. II. Study of motor unit territory. Electro-histoenzymologic correlations.',0 'Workers with pleural thickening had decreased pulmonary function in comparison to those who did not.',0 'Binding isotherms constructed by the method of fluorescence lifetime titration showed that HSA bound preferentially the carboxylate forms of C, HC, MC, and CMC over their lactone forms, thereby providing an explanation for the shift to the right in the lactone-carboxylate equilibrium observed for each compound upon HSA addition.',0 '[Hereditary heterozygote factor VII deficiency].',0 '[Seasonal variations in serum-GPT activity? (authors transl)].',0 'Our results showed that the use of a DNA probe to the detect TEM-type beta-lactamases using a non radioactive probe, could be a suitable alternative to isoelectric focusing.',0 'and glucose-6-phosphate (3.66 +/- 0.19 in control to 2.18 +/- 0.10 mumol/g dry wt.)',0 'Temperature-dependent experiments (5-25 degrees C) yielded the following thermodynamic parameters for the electron-transfer reaction of adrenodoxin: enthalpy (delta H0), -13.6 +/- 0.7 kcal/mol; entropy (S0red-S0ox), -49.6 +/- 2.4 eu.',0 'Cerebral haemangio-endothelioma.',0 'Eight months later, a newly appearing abnormal hyperdiploid karyotype, 47,XY,5q-, +21, was observed in 74% of the cells analyzed, which was associated with evolution of the disease when a pathologic diagnosis of a myeloproliferative disorder was made.',0 'Quality of care in general practice--lessons from the past.',0 'Combined action of M and other agents revealed: stimulation of M-induced hemolysis by Triton X-100 used at concentrations by two orders of magnitude lower than lytic concentrations; saponin acted similarly but at concentrations closer to those known to lyse cells: chlorpromazine inhibited the hemolysis at sublytic concentrations.',0 'The contractile properties of human motor units during voluntary isometric contractions.',0 'The last decade has seen significant progress in the development and specific clinical application of selective psychotropes.',0 'These results demonstrate that while both IL-5 and IL-6 may act as differentiation factors for B cells, they induce differentiation by using at least partially distinct molecular pathways.',0 'Liposome immunoassay (LIA) for gentamicin using phospholipase C.',0 'They were associated with a Mg-ATPase which could be solubilized with dichloromethane from vesicle membranes, and which elutes upon gel filtration with a mol.',0 'Physical characterization of N4-coded messenger RNA.',0 'Automatic computer analysis provided the autoregressive power spectral density, as well as the number and relative power of the individual components.',0 'These findings indicate that in the vitamin D-deficient state, both circulating parathyroid hormone and the plasma concentration of phosphate can significantly modulate the activity of 25-OHD3-1 alpha-hydroxylase in the absence of vitamin D or its metabolites.',0 'Medical ethics and society. II. Professional co-workers.',0 'We have also made the same determinations in the developing bursal follicles before and after hatching.',0 'All patients were treated by surgical resection.',0 'Porphyria diagnostics had not been considered previously.',0 'Quenching of fluorescence of deoxyribonucleic acid-bound hydrocarbons.',0 'It had no peripheral neuromuscular blocking properties.4.',0 'Plasma half-lives of IPM and CS were 1.4-1.6 hours and 1.7-2.1 hours, respectively.',0 'Owing to the sensitivity of coronavirus to acid (pH 3) and alkaline pH (pH greater than or equal to 10), adsorption was optimal at pH 3.3 and elution at pH 9.',0 'were especially resistant to piperacillin and ceftazidime but not cefpirome or imipenem.',0 'Mantel-Haenszel analysis of Oxford data. I. Independent effects of several birth factors including fetal irradiation.',0 'Conservative treatment was performed in this case also, and changes shown by CT scan were almost the same as those seen in the first case.',0 'Studies on the inhibitory effect of verapamil on the slow inward current in mammalian ventricular myocardium.',0 'Laminin was capable of mediating the adhesion only when present at a higher concentration.',0 'Orthopedic nursing. Part 2. Preventing orthopedic complications.',0 'Intravenous midazolam for upper gastrointestinal endoscopy: a study of 800 consecutive cases relating dose to age and sex of patient.',0 'The physiological significance of these observations is discussed.',0 'Bone marrow cells were removed and migrated toward newborn thymus supernatant in an in vitro migration assay in blind well chambers.',0 'A residual "stone trace" is not a rare finding after impulse destruction of large stones.',0 'We have investigated lymphocyte subpopulation levels with monoclonal antibodies in newly diagnosed insulin-dependent (type I) diabetics and in unaffected siblings of type I diabetic probands with islet cell antibodies.',0 'There was a loss of Safranin-O stain at 6 weeks, which persisted at 3 months, although some cells showed increased Safranin-O staining in the surrounding matrix.',0 'Evidence of content, construct, concurrent, and discriminant validity has been demonstrated.',0 'Effects of benzimidazole compounds on mice infected with secondary cysts of Echinococcus granulosus.',0 'The antigen in immune deposits induced by 2 wk of chronic antigen administration was solubilized and was removed within 48 hr of administering excess antigen.',0 'We found this antigen in two patients later, between the 90th and 110th days, in the lavage fluid concentrated fifty times.',0 'However, the combined E + P regimen resulted in significantly higher ketonemia, greater hypoalaninemia, and relatively higher triglyceride concentrations than in control groups during fasting.',0 'Trends and risk factors for HIV-1 seropositivity among outpatient children, Kinshasa, Zaire.',0 'SD rats fasted overnight were anesthetized and instilled 0.1N HCl into the stomach.',0 'Many children spontaneously resolve the structural problems responsible for their intoeing gait.',0 'The enhancement of 3H labelled-prolactin synthesis induced by ethanol was suppressed by cycloheximide.',0 'The natural history of valvular pulmonary stenosis is modified by the surgical treatment of these patients.',0 'The dorsal and lateral aspects of the ventral nuclei are covered by a granule cell layer.',0 'Immunoblotting revealed that in adrenal medulla both chains migrate very closely together in two-dimensional electrophoresis.',0 'The interaction of this group with water soluble substances is not very well understood.',0 'Similar to ketotifen, the effect of KW-4679 on histamine-induced increase in dye leakage was almost same as that induced by antigen.',0 'Thirty-five 1-day-old Pekin-Aylesbury ducks were inoculated intravenously or intraperitoneally with duck hepatitis B virus, and the time-course of infection was examined by Southern-blot, dot-blot, and in situ hybridization and by immunohistochemistry.',0 '[Multiple arterial stenoses and retroperitoneal fibrosis secondary to ergotism].',0 'Urinary recovery of trans-CBZ-diol was 90 +/- 11% (mean +/- SD) of the dose, indicating almost complete absorption.',0 'The lighting of each cigarette was paced at both twice and four times that of subjects baseline smoking rates in a three condition repeated measures design for eight smokers.',0 'Allergic dermatitis from Viruserol ointment probably due to tromantadine hydrochloride.',0 'A role of retroviruses in human leukemogenesis is suggested by epidemiological observations and by the isolation of such viruses from several human T-cell leukemias and lymphomas (human T-cell leukemia/lymphoma virus or HTLV) as well as by biochemical association of retroviral markers with human leukemias.',0 'Adolescent mothers paired with an older man also perceived less marital conflict than adolescent women whose partners were adolescents.',0 'Quantitative measurements were made of brain mast cell (MC) degranulation in juvenile albino rats.',0 'The glycine synaptic receptor: evidence that strychnine binding is associated with the ionic conductance mechanism.',0 'The riboflavin status of subjects was monitored by erythrocyte glutathione reductase assay and urinary riboflavin excretion.',0 '[The result of the survey on midwives duties. C. Future of midwives clinical assignments].',0 'The effects of oral calcium loading on the development of hypertension were studied in spontaneously hypertensive rats (SHR).',0 'Therefore, on the one hand, completely new aspects of psoriasis and therapy can be recognized, and on the other hand, of the effects of SUP.',0 'A marked decrease in l/l0 in the presence of alpha- and beta-glycerophosphates supported the statement that the cathionic center is a part of the enzyme active site SII.',0 'Enamel surface evaluations after clinical treatment and removal of orthodontic brackets.',0 'A combination of neuroanatomic techniques was used to examine the origin and neuropeptide content of nerve fibers in the airway epithelium of adult cats.',0 'The reliability and validity of the instruments used to measure these variables have been established.',0 'Unexpectedly, stratification was impaired, intermediate filaments were noticeably reduced, and cornified cell envelope formation was delayed in transfectants.',0 'Hormonal control of uteroglobin secretion and preuteroglobin mRNA content in rabbit endometrium.',0 'The presence of the positive effect of exogenic estrogens only in the intact males was connected with the estrogen depression of testis function.',0 'The combination of a noncystic mass and fluid in the cul-de-sac (found in 22% of all patients with ectopic gestations) was the best predictor of an ectopic pregnancy with a 94% positive predictive value.',0 'Field stimulation with a single pulse (1.0 ms, 20 Vcm-1) produced a depolarization of 3-7 mV.',0 'Enhancement of 5-HT release, conversely, was not blocked by 8-phenyltheophylline suggesting it to be mediated by a cyclic AMP-independent mechanism.',0 'Periodontal health of submarine school candidates: a correlative analysis.',0 'The density and function of epidermal dendritic cell populations were investigated in aged C57BL/6J mice.',0 'In vitro, the compound showed potent enzyme inhibition and 50-fold selectivity for acetylcholinesterase (EC 3.1.1.7) as opposed to butyrylcholinesterase (EC 3.1.1.8).',0 'Antagonism of cocaine, amphetamine, and methamphetamine toxicity.',0 'Drop plate culturing yielded 2 to 10 colonies per plate of organisms that did not match outbreak organisms.',0 'Rats (190 g) were given the following oral treatments.',0 'Resting membrane potential (RMP) and indexes of accommodation (IA) were obtained from the brachioradialis muscle in rats subjected to 2 or 5 h of bilateral hindlimb tourniquet.',0 'The near future will show whether the compounds under evaluation hold promise for being new, valuable medicines for treating major diseases like Parkinsons disease and schizophrenia.',0 '[Immunoglobulins in the diagnosis of rubeola].',0 'The effectiveness of continuous compared with intermittent amoxicillin prophylaxis administered to subjects with a history of recurrent otitis media enrolled during the winter respiratory infection season was assessed in a prospective single blinded clinical trial.',0 'The prevalence of SANCS in control groups was 30% in non-diabetics and 23% in diabetics.',0 'Metabolism of a DDT metabolite via a chloroepoxide.',0 '[Physiological characteristics of the chemoreceptor structures of the posterior hypothalamus].',0 'Insulin suppressed the leucine Ra an average of 18.4% in the control group, 20.4% in the obese group, and 24.1% in the reduced-obese group.',0 'HLA typing of cultured amniotic cells for the prenatal diagnosis of complement C4 deficiency.',0 'Replacing Leu-182 by Ala in yeast alcohol dehydrogenase (YADH; alcohol:NAD+ oxidoreductase, EC 1.1.1.1) yields a mutant that retains 34% of its kcat value and makes one stereochemical "mistake" every 850,000 turnovers (instead of approximately 1 error every 7,000,000,000 turnovers in native YADH) in its selection of the 4-Re hydrogen of NADH.',0 'Studies on the stability and protein adsorption characteristics of heparinized polymer surfaces by radioisotope labeling techniques.',0 'An ATP-activated cation conductance in human epididymal cells.',0 'Fourteen New Zealand White rabbits with respiratory signs of naturally occurring Pasteurella multocida infections were treated with either an injectable or water-soluble oral formulation of enrofloxacin.',0 'New method for the spectrophotometric analysis of mixtures. I.',0 'Corynebacterium acnes strains cross-resistant to clindamycin and erythromycin were observed following long-term selection or mutagenic treatment in the laboratory.',0 'In contrast, in seven infants with gastroparesis related to prematurity, metoclopramide did not significantly change gastric emptying.',0 'A comparison of girls and boys with teacher-identified problems of attention.',0 'Recordings of spontaneous and evoked PSPs suggest that mossy cells receive more excitatory input and less inhibitory input than CA3c pyramidal cells.',0 'In both infected groups, less muscle stretch was required to reach the length at which Tpd was produced.',0 'Prevalence, incidence, and risk factors of hepatitis C virus infection among drug users in Amsterdam.',0 'This was reflected by the increase in PO2 with no change in alveolar ventilation.',0 'Effect of endotoxic shock on renal and hormonal functions.',0 'The distance between the skin and the large retroperitoneal vesses is generally equal to one-third of the antero-posterior abdominal diameter.',0 'The minimum concentration of bupivacaine required for successful block was between 325 and 406 mumol/litre.',0 'Seiture activity during sleep was never observed in the REM phase of sleep.',0 'The complication rate following percutaneous arterial studies is lower than is the reported experience with cut-down arteriotomies.',0 'Peripheral venous blood samples were drawn for measurement of serum cholinesterase activity.',0 'The patients later onset of temperature elevations was a result of an aspiration pneumonia.',0 'Extended three-compartment model for the transport and distribution of Hippuran.',0 'Lactate studies in the convalescent period revealed normal response and repeat physical exertion of same severity after 6 months did not reproduce the syndrome.',0 'The most striking aspect was the multiphase course of lymphoblastic response in every individual patient.',0 'Blood and urine samples were collected over 24 hours after the dose.',0 'They presented a quantitative study of the distribution of paroxysmal activity in the epileptic, based on an experimental observation and confirmed as a result of the methods used.',0 '[Radioimmunoassay of circulating carcino-embryonic antigen. Immuno-perchloric extraction of serum].',0 'Currently, there are no generally accepted rules for second-line management, either endocrine or by other means.',0 'This MoAb recognized a 43 kD polypeptide that can covalently associate on the T-cell surface with several other molecules to form a multimeric complex.',0 'Planned excisions of tumors involving the abdominal or chest wall should not be compromised because of lack of tissue for wound closure.',0 'Since the cells in layer II which sprout following lesions can be identified at both the light and elctron microscopic level, a potentially valuable model system is available in which to analyze cellular changes during sprouting.',0 'On admission to the department, rehabilitation (in 17 days after the operation, on the average) of 50% of patients was referred to group IV.',0 'Reactivation of dormant chick erythrocyte (CE) nuclei was studied by fusing chick red cells with rat myoblasts, HeLa cells, and chick fibroblasts.',0 'Crest cells dispersed most rapidly and extensively on fibronectin.',0 'The effects of National Health Insurance on Canadian Psychiatry: the Ontario experience.',0 'Chemical ionization mass spectrometry of dichlofluanid and its major metabolite.',0 'Noninjected rats served as controls.',0 'Metabolism of 2,4-DNT by liver and lung microsomes yielded mainly 2,4-DNBAlc with lower amounts of 4A2NT and 2A4NT, and their formation was dependent on the presence of oxygen and NADPH.',0 'The release of soluble tumor necrosis factor receptors was strongly (80-90%) inhibited in the presence of the neutralizing antibody.',0 'Intrapreoptically microdialyzed and microinjected norepinephrine evokes different thermal responses.',0 'Effects of cadmium on carbonic anhydrase activity and hemoglobin content of rat testes.',0 '[Tracheoesophageal fistula after blunt thoracic trauma: recognition and treatment].',0 'However, reported outcomes and risk factors for this problem are based on small series and anecdotes.',0 'Single-channel analysis of a K channel at basolateral membrane of rabbit proximal convoluted tubule.',0 'NMS should be included in the differential diagnosis of a febrile patient with a history of any neuroleptic treatment, including clozapine.',0 'In three of the asthmatic and four of the CF outliers, the changes were as predicted, that is, both tests returned toward normal, or both became more abnormal.',0 'Nitric oxide is believed to mediate the inhibitory effects of cytokines on glucose-stimulated insulin secretion by both rat and human islets.',0 'Therefore, the specificity of the sulfatase of Clostridium sp.',0 'Cellular and molecular mechanisms of haemoglobin switching in man.',0 'Phenotypic characterization revealed that the predominant leukemic cells were classic "null" lymphoid cells with a minority component of pre-B cells.',0 'Duodenoscopic sphincterotomy (DS) is a well established treatment for common bile duct (CBD) stones in post-cholecystectomy patients, but not in patients with gallbladder in situ.',0 'Evaluation of a new oral diuretic agent. Ethacrynic acid and ethacrynate sodium (Edecrin and Edecrin Sodium).',0 '[Treatment of congenital incompetence of the anal constrictor].',0 'Growth and development of the Lumi child in the Sepik district of New Guinea.',0 'All parameters returned to pre-sedation levels within 5 min in all patients in the flumazenil group, with significant differences as compared with placebo after 5, 15, 30, and 60 min.',0 'We conclude that the contribution of the alveolar sacs to the asymmetric morphologic structure of the acini has no consequences for the shape of the expirograms of He and SF6.',0 'Together, the data suggest that in class I-deficient mice vaccinated against T. gondii, the absence of CD8+ effector cells is compensated for by the emergence of a population of NK1.1+ and asialo GM1+ cells which lack cytolytic activity, and that the protective action of these cells against the parasite is attributable to IFN-gamma production.',0 'The implications of the detection of proteinuria and microalbuminuria in insulin and non-insulin dependent diabetes.',0 'The rat isolated superior mesenteric bed, perfused with Krebs-Henseleit solution containing 10 microM indomethacin and precontracted with 100 microM methoxamine, was used to study the vasorelaxation produced by some fragments of endothelin-1, by two alanyl-substituted analogues, and by human and porcine proendothelins.',0 'The actuarial survival rate without recurrent bleeding was 96% at two years, 88% at five years.',0 'In normal fibroblasts, approximately 48% of the total CK activity was of the MM type, 40% was of the BB type, and 12% was of the MB type with no significant differences apparent between normal and DMD groups.',0 'A nonhydrolyzable analog of GTP stimulated fusion at low cytosol concentrations and inhibited fusion at high cytosol concentrations.',0 'In the femoral neck, however, there were significant differences in assignments between instruments, expressed both as a percentage of young normal (mean difference 6.2%) and with respect to age-matched values (mean difference 3.3%).',0 'The effects of verapamil, though less marked than its peak effects, were still present 70 minutes after administration.',0 'Influence of leukemia P388 on the pharmacokinetics of mitoguazone in B6D2F1 mice.',0 'The presence of low systolic-diastolic murmur suggests a common arteriovenous coronary orifice and by means of coronarography it is possible to make a topical diagnosis.',0 'Diminution of glomerular filtration rate, renal plasma flow and associated tubular function with age have been well documented.',0 'Mean weights at six weeks of age showed that poults hatched from eggs dipped in tylosin and spiramycin were 128 and 130 grams heavier than control birds.',0 'Stefans equations are more appropriate.',0 'No HSV DNA was detected in the 4 neonates without CNS disease, the 1 patient with presumed HSE, the 6 patients who had HSE excluded from the diagnosis, and the 105 control patients.',0 'Single or multiple rib fracture, in 193 (77.8%) patients, was the most frequent thoracic injury, followed by 94 (37.6%) cases of hemothorax and 80 (30.2%) instances of pneumothorax.',0 'The correlations between the 24, 48 and 72 hour concentrations and steady-state concentration were very good (r = 0.81, 0.97, 0.94; p less than 0.0001) and better than the correlation between half-life and steady-state (r = 0.65; p less than 0.01).',0 'Each of the 5 affected eyes had severe initial loss of vision to less than 20/400, and only one of these eyes had significant visual recovery.',0 'It is suggested that these different ions affect RH either by altering the hydration layer or possibly by some effect on DNA structure, such as stabilizing bends.',0 'Macromolecular synthesis in bluetongue virus infected cells. I. Virus-specific ribonucleic acid synthesis.',0 'These findings are relevant to the interpretation of total plasma or serum concentration, and may explain the rarity of serious quinine toxicity in severe falciparum malaria.',0 'Structural changes which normally accompany transmitter release at frog neuromuscular junctions are visualized with the freeze-fracture technique.',0 'We have investigated the in vivo and in vitro effects of DFP on hen brain tubulin polymerization.',0 'This compound possesses the same reactivity towards SH-groups as uncoupled p-CMB.',0 'Evidence was obtained for an indiscriminate cellular uptake of variable amounts (4-22%) of intact dietary methyl and ethyl esters of fatty acids, which, however, appeared in the chylomicrons only to a very limited extent (0.1-1.0% of total lipid).',0 'Administration of oxytocin at 200 pmol/min produced plasma oxytocin levels of 26.0 +/- 2.1 pmol/l and caused a significant diuresis and natriuresis.',0 'This model provides some insight into what might be required to increase ones swing.',0 'We examine the asymptotic power of the test for treatment effect and compare it with that of a simpler analysis.',0 'Initial experiments designed to validate the assay revealed that the number of IL-1 beta spot forming cells was increased by exposing normal blood monocytes to LPS and that spot formation was prevented by incubating the cells with cycloheximide.',0 'Degradation rates obtained using data from a series of 2 h inhibitor in vitro incubations were respectively 0.989, 0.134, and 0.037/h for casein, solvent soya-bean meal (SSBM) and expeller soya-bean meal (ESBM).',0 'We have previously shown that increasing T3 concentrations within the physiological range down-regulates NBT3.',0 'Four of the patients never showed symptoms of steroid psychosis; the remaining two continued to show steroid dementia well after their steroid psychoses had resolved.',0 'RESULTS : Patients in risk group pT 4a, pN O (primary tumor thickness of more than 4 mm or invasion of subcutis and absence of regional lymph node metastasis in elective lymph node specimen) have a 5-year survival rate of 72.8%.',0 'The relevance of the distribution of the contrast medium in the CSF space to the occurrence of headache is discussed.',0 'Prevalence of hypercholesterolemia in black patients of a neighborhood health center.',0 'Effects of anterior temporal lobectomy apart from the relief of seizures: a study of 40 patients.',0 'These conditions implied the presence of intracellular or firmly attached proteinase which could be partially released.',0 '[Serum TSH-activity--interpretation of the test results].',0 'New collagen implant as dural substitute.',0 ', big rose cutters (R 16) create noise levels of 95 dB (A) and above, and only diamond round bits create less noise (approximately 88 db [A]).',0 'From the morphological point of view, vagal branches could be classified into two categories, i.e., the branchial branches primarily related to the pharyngeal arches, and intestinal arborization derivatives which are associated primarily with the primitive gut.',0 'In Australia and in some parts of the United States, the majority of patients with intermediate thickness melanoma (1.6-4.00 mm) will undergo elective lymph node dissection.',0 'Diagnostic and prognostic problems in early gastric cancer.',0 'This may demonstrate that human tumor cytogenetics are a dynamically and vigorously developing branch of cancer research.',0 'From the estimated V(max.,) it was concluded that hamster lung cells have less capacity to metabolize orotic acid than have liver cells.',0 '[Aging and carcinogenesis (authors transl)].',0 'Cervex-Brush and Cytobrush. Comparison of their ability to sample abnormal cells for cervical smears.',0 '[The diagnostic method of localization of cerebrospinal fluid rhinorrhea by digital video subtraction system].',0 'The effects of metabolism improving agents: an electrophysiological study.',0 'The V320 produced reliable results comparable to the PARVA-HF.',0 'The safety of HT/RBC in humans has been documented, and the experiments in dogs suggest that it may have advantages over other agents in detecting gastrointestinal bleeding.',0 'In neither of the 2 families was there consanguinity or history of other abdominal wall defects.',0 'Aeromedical aspects of civil aviation accidents.',0 'Growth hormone receptor deficiency in Ecuador: clinical and biochemical phenotype in two populations.',0 'Decennial incidence rates in males in their fifties and sixties were significantly higher than those in females.',0 'The data suggest that 17-beta-estradiol doesnt increase the number of TRH receptors on pituitary cell surface, but stimulates prolactin synthesis.',0 'It is shown that one molecule of this toxin withdraws 10 +/- 2 dipalmitoylphosphatidylcholine molecules through cooperative transition.',0 'The analysis of the results obtained explains the differences, often important, of these results with the different methodological impostation of Steiner, Ricketts, and Cervera.',0 'Urine samples were collected from 200 subjects undergoing intravenous pyelography.',0 'With one exception, all of the field isolates generated RE digestion patterns identical to an embryo-propagated vaccine strain of ILTV when the six-base-recognizing REs EcoRI, HindIII, PstI, and BamHI were used.',0 'The deduced amino acid sequences of the Tbp2 proteins were nearly identical to those presented in previous studies.',0 'One group of 8 patients with primary biliary cirrhosis and one group of 7 patients with common duct stone both had generally high levels of blood coagulation factors and a wide range of other plasma proteins.',0 'Although the 8% diet group displayed significant reductions in fusiform and ovoid cells, the 6% diet group showed the most intense reductions in cell size of the three cell types.',0 'Risk factors for epidemic Xanthomonas maltophilia infection/colonization in intensive care unit patients.',0 'Stump carcinoma after Billroth I resections.',0 'The observations support an hypothesis that alterations in one component of the connective tissue matrix may influence the deposition and structure of others, ultimately, modifying the overall organization and mechanical properties of the tissue.',0 'OBJECTIVE : A radiographic study was undertaken to describe the relationship between the magnitude of coupled lumbar motion in lateral bending and the presence of low back pain: correlation between pain and motion, relationship between motion category and motion and symmetry of lumbar motion.',0 'The cis-acting control site mutant, amdI9, affects induction by sources of acetyl-CoA specifically.',0 'Golden anniversary of the "British Heart Journal".',0 'The possibility that the exposure of the embryo to certain chemical substances can lead to behavioral disturbances is known from human epidemiological studies, e.g., in chronic poisoning with mercury and ethanol.',0 'The medial septal area (MSA) contains cholinergic and GABAergic neurons that send projections to the hippocampus.',0 'In the anteroventral nucleus spherical cells occupy the rostral pole.',0 'Vaccination also led to the depression of phytohaemagglutinin (PHA) blastogenic response.',0 'As a fistula in the right lower bronchial stump was found tiny by BFS, we tried to close the fistula bronchoscopically with fibrin glue.',0 'Its effects on blood vessels, however, are not as well recognized.',0 'The melanoma DHFR levels are several fold higher than in MTX-sensitive human tumor lines and up to a hundred-fold higher than that measured in human brain tumor cells by our assay.',0 'Altered arachidonic acid metabolism in platelets inhibited by onion or garlic extracts.',0 'These results reveal the relative importance of Phase I and cell-type specific Phase II responses in uterine preparation for implantation.',0 'An extensive questionnaire formed the basis for a personal follow-up interview, which was tape-recorded for further evaluation.',0 'The molecular basis of triosephosphate isomerase (TPI) deficiency was studied in 3 patients from three separate families.',0 'In the present study, aluminum (Al) accumulation has been examined after aluminum loading in mice.',0 'Increasing the number of organ donations.',0 '259, 729-733) by this laboratory.',0 'RESULTS : Core temperature decreased 0.8 degree C in the first hour of surgery in the patients given nifedipine the night before and the morning of surgery, which was significantly less than in the control group (1.7 degree C in the first hour).',0 'Schistosomula of Schistosoma mansoni bind human low density lipoproteins (LDL) in a concentration-dependent and saturable manner.',0 'Cryptococcosis of CNS in AIDS patients.',0 'Transite shows very little aderence to the wound surface.',0 'Studies on the synthesis of plasma glycolipoprotein and hepatic sub-cellular glycoprotein in early choline deficiency.',0 '[Estrus synchronization in the pig].',0 'When treated with Raney nickel, this adduct yields 2-methylimidazole-1-ethanol.',0 'The results demonstrate the existence of intramolecular disulfide bonds that are essential for the promotion of pro-LPH to a native conformation.',0 'This is the second family reported; 16 relatives are affected.',0 'The role of G-proteins in the mediation of the cardiovascular effects of neuropeptide Y and the alpha 2-adrenoceptor agonist clonidine was investigated by injections of pertussis toxin (10 micrograms/30 microliters, i.v.t., 24 h) in the awake unrestrained male rat.',0 '[Amyloid degeneration and chronic pleuro-pulmonary tuberculosis (anatomo-statistical findings)].',0 'Protein synthesis in vitro in rat brain after short-term protein starvation and refeeding.',0 'Many of these factors act to stimulate the growth of both tumour and fetal cells in an autocrine manner.',0 'In the thiamine deficient group, there was evidence of muricide and such increased progressively with advanced thiamine deficient feeding.',0 'It also has trophic effects on the pancreas.',0 'Our data suggest significant regional and pharmacological changes in GABAB binding during development.',0 'The rate of NA disappearance after H44/68 was slower than that of DA in most regions.',0 '[Kinetics of DNA transformations under UV-irradiation].',0 'On days 12, 19, 40, and 61 of lactation, litters were removed for 5 h and after 1 h of resuckling the synthesis of DNA and RNA in the mammary gland was estimated by the incorporation of (3H)thymidine and (14C)uridine into mammary DNA and RNA in vitro respectively.',0 'This study, in biologically bred hyperglycemic diabetic rats, examined the effect of a intravenous insulin infusion (1.5 units.hr-1) on blood, plasma, and brain glucose concentrations to determine their relationship during decreasing blood and plasma glucose levels.',0 'The electronic circuitry has separate timing and energy verification channels and can detect 95% of the coincidences with a timing window (twice the maximum time between two coincident pulses) of 14 nsec.',0 'Classification of follicular lymphoma based on parafollicular small lymphocytes (PSL) offers a new set of prognostic criteria and a guide to improved clinical management.',0 'Splenic lymphocytes were assayed to investigate their phenotyping using flow cytometry, proliferative response against mitogens and allogeneic lymphocytes, cytolytic cell activity, and IL-2 production.',0 'High blood pressure did not appear to significantly increase sudden coronary death but increased the incidence of non-sudden death significantly.',0 '"Things are not always what they seem". Hat-pin injury to the heart--a report of two cases.',0 'Fourteen hip arthroscopies between January 1985 and May 1988 were reviewed.',0 'Tensiometry curves differed markedly at all time points among the groups: Vitamin A curves being broader, higher, and having more spikes.',0 'By contrast, in the parental BNER4 cells, the lysosomes were mostly localized in the perinuclear region.',0 'The activity with N2 as a reducible substrate was very low, implying that acetylene reductase activity is not necessarily an accurate indication of nitrogen-fixing ability.',0 'Acute MDMA injection increased striatal dopamine content (28%) and decreased the DOPAC content.',0 'These studies report the first two-dimensional crystallization of a biologically active water channel and provide direct evidence of the structure responsible for its pore-like behavior.',0 'The vibrotactile sense thresholds (VSTs) of the middle fingers of 60 healthy persons and 97 patients with Hand-Arm Vibration Syndrome (HAVS) or subclinical HAVS were measured quantitatively.',0 'Thioglycolate medium decreases resistance to bacterial infection in mice.',0 '[Radioisotope determination of cortisol secretion rates by thin-layer chromatography].',0 'Fifteen percent of BE examination errors were purely perceptive (ie, the tumor was visible in retrospect).',0 'The prevalence of infection of both species was significantly greater in summer than in winter (p = less than 0.05).',0 'Decreased globin messenger RNA in thalassemia by hydridization and biologic activity assays.',0 'A specific corresponsion between the sensibility of inhibitory substance and the biological properties of the staphylococci was not observed.',0 'Secular trends in mortality rates from motor neuron disease in Kentucky 1964-1984.',0 'Spontaneous and stimulated GABA release was analyzed for comparison.',0 'USA (1972) 69, 2850-2854] are examined.',0 'Preinfusion anxiety and laboratory-induced panic attacks in panic disorder patients.',0 'The human dander atopy. II. human dander, a complicating factor in the study of the relationship between house dust and dermatophagoides allergens.',0 'A direct comparison of the role of leukotrienes in mediating the increase in microvascular permeability associated with guinea pig tracheal and cutaneous anaphylaxis was obtained by simultaneous administration of inflammatory stimuli to both trachea and ear.',0 'The mechanism of the inhibition of sodium transport in the toad bladder by hyperbaric oxygen was not known.',0 'Four story conditions were presented: (1) easy structure--T.C.; (2) complex structure--T.C.; (3) complex structure with pictures--T.C.; and (4) create-a-story--pictures.',0 'In particular, 70 of 97 units (i.e. 72.2%) were excited during side-down neck rotation and depressed during side-up rotation, while 19 of 97 units (i.e. 19.6%) showed the opposite pattern.',0 'Especially when combined with cytotoxic chemotherapy, limited surgical excision, or both, irradiation has been shown to control disease in the primary site and regional nodes without the need for surgical extirpation as frequently as in past years.',0 'Thirty-nine cases of this disease were hospitalized at the neurological department of the hospital in Grudziadz.',0 'Scombrotoxic (histamine) fish poisoning.',0 'It is suggested that rapid cooling to 4 degrees C may promote release of cortical granules and a premature zona reaction.',0 'Clinical side effects were of mild intensity and included cheilitis, conjunctivitis and pruritus.',0 'The transmural distribution of myocardial blood flow and myocardial lactate consumption remained unchanged.',0 'One year after irradiation and dietary supplementation, half the surviving mice were switched back to the control chow.',0 'The family size preferences of young people: a replication and longitudinal follow-up study.',0 'Pretreatment of the microsomes with p-hydroxymercuribenzoate, a sulfhydryl-blocking agent and an inhibitor of PGH2----PGE2 isomerase, did not limit lens microsomal PGE2 formation (24% vs. 39%) but dramatically inhibited PGF2 alpha production (25% vs. 6%).',0 'Semen samples from six patients were unremarkable except for one sperm count that fell in the low-normal range.',0 'An analysis of variance indicated that even within such functional subgroups of motoneurones, rheobase was appreciably better correlated with membrane time constant than with estimated cell size.',0 'HLA-DR: serology versus restriction fragment length polymorphism.',0 'In addition, the availability of living-donor programmes slows down attempts to establish cadaver-donor transplant programmes.',0 'Calmodulin and troponin C exhibit calcium-dependent binding of 1 mol/mol of dynorphin.',0 'In a field experiment, Pseudomonas cepacia J82rif and J51rif increased sunflower emergence in the presence of the fungus Sclerotinia sclerotiorum.',0 'Variant cells have been isolated previously that are fully resistant to the dexamethoasone inhibition of plasminogen activator activity.',0 'Our diagnostic imaging approach has resulted in remarkably improved thyroid cartilage imaging by CT when "directed" by preliminary ultrasound.',0 'Muscle spasm often outlasted voluntary contraction by 30 seconds or more before subsiding into myokymia and fasciculations.',0 'CONCLUSION : The 6-minute walk test is a safe and simple clinical tool that strongly and independently predicts morbidity and mortality in patients with left ventricular dysfunction.',0 'A muscle selected for biopsy must be obtained atraumatically with the fibres orientated longitudinally.',0 'Heterotopic liver transplantation for fulminant Wilsons disease.',0 'Water intake was studied in six goats during late pregnancy to investigate if heat stress induces primary polydipsia.',0 '[Yellow nail syndrome: description of a case and review of the associated pathology].',0 'Platelet ultrastructure, 5-HT uptake and content of adenine nucleotides, platelet factor 4 and beta-thromboglobulin are all within normal limits.',0 'The intensity of the positive reaction was inhibited when the tissue was incubated with 10(-8) M unlabeled motilin and was completely abolished by 10(-7) M unlabeled motilin.',0 'The 64Cu incorporation into uncloned fibroblast cultures from 16 Menkes disease mothers and 19 first and second degree female relatives was examined.',0 'It was concluded that the circadian rhythmic changes in disaccharidase activities are controlled by an endogenous mechanism, and that some circadian time-keeping system participates in this mechanism.',0 'One implication of the patch structure is the presence of high levels of linkage disequilibrium, caused by isolation by distance even for unlinked loci, at some spatial scales; yet the disequilibrium in the large total populations is near 0.',0 'There are several possible reasons for the disparity between the apparent high incidence of neonatal infection and low prevalence of maternal carriage.',0 'The electrophysiological data of 23 adult patients with Lambert-Eaton myasthenic syndrome (LEMS) have been reviewed.',0 'The use of hypnosis in the rehabilitation of complicated vascular and post-traumatic neurological patients.',0 'These results suggest that the direct-acting Michael-type reaction has activity relevant to producing a genotoxic effect.',0 'Finally, an approach that generates mutant structures from the native structure by molecular dynamics simulation and then uses these configurations in PDLD calculations is found to give a reasonable estimate of the effect of the mutation on the corresponding redox potential.',0 'It is concluded that additional research on the relation between lipoprotein modification and the immune system, and on the possible beneficial effects of antioxidants in atherogenesis is warranted, not only to elucidate further the mechanism of atherosclerosis, but also to develop new approaches to the prevention of atherosclerosis.',0 'Studies on the nutrition of some antibiotic producing Streptomycetes. 1. Amino acid requirements.',0 'Comparison of the two test results showed that of the 35 patients with abnormal OKP tests, in 26 the result was a true positive (HVFA also abnormal) and in 9 a false positive (HVFA normal).',0 'Evidence is presented for transcription by the normally inactive micronucleus just prior to the maximum crescent stage, confirming an earlier report.',0 'Three cell types, including chicken embryonic cells transformed by Rous sarcoma virus, human malignant melanoma cell line LOX, and human breast carcinoma cell line MDA-MB-231, retain the invasive phenotype in vitro, express invadopodia, degrade and enter into a fibronectin-rich collagenous matrix.',0 'It was anticipated that this installation and an accompanying workshop on the analysis of health, population, and family planning data by microcomputer would enable the faculty at NIPSOM to share the results of their research with other public health and medical colleagues, provide administrators with timely analyses for policy or program implementation, and assist with internal management of information essential to the workings of the institute.',0 'These results suggest that diabetic Chinese hamsters produce polyol accumulation in tissues but that there is a clear species-specific difference to inhibition of aldose reductase.',0 'Congenital complete atrioventricular block is an uncommon disorder with a prognosis which is usually favorable.',0 'Eicosapentaenoic acid stimulated water flow, and the stimulation was blocked with indomethacin.',0 'Control for energy and fat intakes allowed the protective influences of additional dietary patterns to be expressed.',0 'On the basis of this experience, we suggest a step-by-step approach: (1) insertion of chest tube after 3 to 4 pleural punctures; (2) 1-week trial of MCT diet, with intravenous support to correct protein losses; (3) TPN if chylothorax increases or persists with large volumes; (4) Doppler echocardiography or phlebography to rule out obstruction of major thoracic veins; and (5) insertion of TPN line in inferior vena cava in case of such obstruction; and (6) direct surgical approach to the thoracic duct after 4 weeks of unsuccessful nonoperative treatment.',0 'The examination can be carried out only by treating fresh, non-fixed materials with a deeply cooling knife of the routine cold microtome (Model X).',0 'The subjects performed 30 min of cycle exercise (70% of individual maximal O2 uptake) in a cool [21 degrees C, 30% relative humidity (rh)] and a hot (49 degrees C, 20% rh) environment before and again after they were heat acclimated.',0 'It thus appears that the I-C subregion of the H-2 complex controls suppressive cell interactions in this T-cell-mediated immune response.',0 'A perspective on therapy of Lyme infection.',0 'Effects of serotonin neurotoxins on pituitary hormone release.',0 'Androgen receptors: relationship to growth response and to intracellular androgen transport in nine variant lines of the Shionogi mouse mammary carcinoma.',0 'In rabbits with sinoaortic and vagal deafferentation, the responses of heart rate and RSNA to a fall of blood pressure were abolished during both CGRP and SNP infusion.',0 '[General principles concerning full crowns as abutments of fixed bridges].',0 'It was found that the C1, carboxyl carbon of glutamate becomes the amino-bearing (C5) carbon of delta-aminolevulinate and forms the formaldehyde on cleavage.',0 'A 10-year matched-pairs study comparing azathioprine and no immunosuppression in multiple sclerosis.',0 'Selected area reflection electron diffraction has been used to determine the phases present in the reaction zones surrounding the Ag-Cu eutectic dispersant in Dispersalloy amalgam.',0 'We review the incidence of articular manifestations in cases of Waldenströms macroglobulinemia and the possible pathogenetic mechanisms involved.',0 'These results show that isolated intestinal epithelial cells express the PRL receptor gene as well as specific binding sites with a high affinity for PRL.',0 '[Selected problems of dermatologic allergology].',0 'Thirty-two genetically lean and obese Yorkshire X Duroc crossbred castrated male pigs were divided within genetic line into two groups at 7 weeks of age.',0 'Survey of dietary policy in British diabetic clinics.',0 'The gene region was mapped by subcloning and Tn5 insertion mutagenesis.',0 'The average age at operation was 16 years.',0 'In the previous paper (Gerfen et al., 1987) mesostriatal dopaminergic neurons were shown to be subdivided into dorsal and ventral tiers that project to the striatal matrix and patch compartments, respectively.',0 'In all 26 patients a considerable increase of the alkaline phosphatase after three months was evident.',0 'Six of the cats were alive after follow-up periods ranging from 6 to 36 months (mean, 21 months; median, 21 months).',0 'The present results raise the possibility of a cell membrane site of action for GTP and guanosine, which mediates the activation of soluble guanylate cyclase and leads to increased nitrovasodilator-induced cyclic GMP accumulation and arterial smooth muscle relaxation.',0 'Spinal cord monitoring during spinal surgery using somatosensory spinal evoked potentials.',0 'Stereological analysis of thyroid follicle structure.',0 'The effect of breast feeding on pituitary thyroid function of normal babies also was studied.',0 'Thus prior stress can increase the strength of an electrical synapse formed between sprouting neurons.',0 '25% of the RT group patients had a moderate or mild complication versus 10% in the RS group but 2/3 of these complications recovered without sequellae.',0 'Therefore, it is most likely that apoA1 released by the injured nerve originated from the bloodstream and the increase in apoA1 content seen in the crushed nerve of alcohol-fed rats is due to an enhanced permeability of the nerve-blood barrier.',0 'The release of enzymes from Escherichia coli by osmotic shock and during the formation of spheroplasts.',0 'Furthermore, the peak of polysomal ODC-mRNA activity preceded that of ODC activity or ODC protein by several hours.',0 'Thus far the great majority of gram-negative urinary tract isolates have been susceptible to aminoglycosides and to third-generation cephalosporins.',0 'Psoriasis and inflammatory arthropathy was present in 168 patients, of whom 94 have been followed up for more than 10 years.',0 'Its size as determined by sodium dodecyl sulfate-polyacrylamide-gel electrophoresis and size exclusion chromatography was 68 kDa, suggesting that the MTase exists as a monomer.',0 '[Biochemical bases for the effect of combining kanamycin and nitrofuran resistance genes in Escherichia coli cells].',0 'We suggest that low blood levels of Vit E, GSH-Px and particularly PUFA-PL may play a pathogenetic role in the onset and development of AIDS and other infections.',0 'Free-radical attack upon uric acid generates allantoin [Ames, Cathcart, Schwiers & Hochstein (1981) Proc.',0 'Episodic and TRH induced growth hormone release in primary hypothyroidism of man and rat.',0 '(i) The uptake studies revealed that about 60% of the total K+ net flux is inhibited by ouabain and therefore mediated by the Na+-K+-ATPase.',0 'In the method being presented, the microenvironment effects have been significantly reduced by denaturing the dye/protein complex in 6 M guanidine hydrochloride prior to making the necessary spectrophotometric measurements.',0 'Amplified ELISA differs from conventional direct double antibody sandwich ELISA (DAS-ELISA) in the enzyme substrate reaction.',0 'Why another examination?',0 'Provocative pacing studies were performed in 5 cases of inducible VT under therapy.',0 'Chemotherapy and veno-occlusive disease of the liver.',0 'However, both the magnitude and behavior of the electrostatic stabilization as a function of solution ionic strength differed for the three cytochrome c-flavodoxin complexes.',0 'Ca2+ uptake by the mitochondria occurs by an electrophoretic mechanism, is inhibited by antimycin A, FCCP, and ruthenium red, and stimulated by respiratory substrates, phosphate and acetate.',0 'When analysed by country of birth, Australian born residents showed a greater decline, while men born in Greece and Italy may have had an increase in IHD mortality.',0 'FH rats do not closely resemble CHS mice or human beings in having deficient NK activity and cannot be considered the rat homolog of the CHS.',0 'Covariate analysis of the multiple linear regression of mean growth hormone concentration on age and percentage of ideal body weight in Turners syndrome indicated that percentage of ideal body weight had a significant effect on endogenous secretion of growth hormone when age was held constant, but not the other way round.',0 'During the hemorrhage, fetal blood volume decreased by 14.3 +/- 1.4%, and arterial pressure (AP), venous pressure (VP), and heart rate (HR) did not change significantly, although fetal plasma renin activity (PRA), arginine vasopressin (AVP), and norepinephrine (NE) were elevated to 1.5-2.5 times their initial values (P less than 0.05).',0 '[The effect of DDT on the functional and morphologic state of the liver].',0 'The concept of incapacity for work has been defined by a number of court decision.',0 'Other characteristics of the normal dog were found, such as the simultaneous occurrence of the following vectors: the peak spatial magnitude vector; frontal plane maximum vector; maximum leftward vector; maximum caudal vector; sagittal plane half-area vector; and transverse plane maximum vector.',0 'The amino-terminal sequence is similar to that of a 13-residue segment at the amino terminus of the eclosion hormone of the silkworm Bombyx mori, but the hormone is not otherwise homologous with other hormones or proteins.',0 'Abuse of paracetamol in childhood fever.',0 'Differentiation of malignant from benign pancreatic mass by Tl-201 abdominal SPECT.',0 'Coordination of services to methadone mothers and their addicted newborns.',0 'The pathophysiology is the same as in priapism because of the similarities in the vascular arrangement of the turbinate and the penis.',0 '4-acetamido-4-isothiocyanostilbene-2,2-disulphonic acid (SITS), an inhibitor of Cl- permeability, reduced the Ca2+-dependent AVP release.',0 'The protein inhibited papain and ficin strongly, and stem bromelain and bovine cathepsin C partially.',0 '[Opportunistic infections in AIDS--diagnosis and therapy].',0 'day post partum a maximum of superficialcells and simultaneously a high grade of cervical mucus arborisation in elongating cyclic intervals can be observed in lactating ewes.',0 'Conductive hearing loss due to secretory otitis media is the commonest form of hearing loss in children.',0 'In vitro studies showed that commercially purified histone H1, and to a considerably lesser extent core histones, enhanced the NiCl2 and H2O2 catalyzed formation of 8-oxo-dG in a reaction containing free dG base.',0 'By gel mobility shift assay, the interaction of Ets1 with the downstream ERR-1-binding region was found to be more stable than its interaction with the upstream ERR-2 region.',0 'Electrical stimulation of the tissue during incubation with [3H]choline enhanced the release by subsequent field stimulation.',0 'Calcified pancreatic pseudocysts.',0 'The combination of edge detection and selective enhancement was shown to produce images of superior contrast on the patients anatomical features as well as accurate definition of treatment field edges.',0 'The Mr = 66,000 and 68,000 proteins chased into the Mr = 74,000 and 82,000 proteins in pulse-chase experiments.',0 'Local pain-killing injections seems to have been used at the beginning of our century in all sorts of indications.',0 'A similar reliability of discrimination could be obtained by comparing these morphometric values in oxyphilic adenomas and carcinomas.',0 'Patient package insert requirements. Statement of the American Society of Internal Medicine.',0 'Overall, the total group of adolescents did not appear to be at significant nutritional risk.',0 'Under an intermittent compressive force up to 8 g, growth continued, but at a lower rate; over 8 g, growth ceased.',0 'Partial trisomy of short arm of chromosome 6: a case due to paternal balanced translocation.',0 'The BMBT of healthy dogs anesthetized with halothane or tranquilized with xylazine were not significantly different from the BMBT of healthy dogs evaluated without chemical restraint.',0 'Patients with isolated Raynauds disease showed a rise in Dsb during cold pressor testing, the mean increase being 8 percent.',0 'Relationship of time focus to distribution of verb tenses.',0 'We usually attempt to prevent the stimulation-tolerance by administration of the monoamine precursors , i.e., 1-dopa and 1-tryptophan, on the basis of the experimental observation reported previously.',0 'These dipeptides were aligned by homology to other plastocyanins of known sequence.',0 'Decline in Category Test performance across age-cohorts was more pronounced for women than for men.',0 'Some of the pta mutants and all of the facA mutants failed to grow on media containing fumarate as terminal electron acceptor or anaerobically on glucose minimal medium.',0 'Neglect of differences in structure between symptoms has also naturally resulted in the neglect of differences in structure between superficially same symptoms.',0 '[Development of labyrinthine deafness and its background from the standpoint of electrophysiology].',0 'The activity of Na+, K-ATPase determined in stomach, duodenum and small intestine was the maximal too.',0 'Influence of prior dietary protein intake on metabolism, DNA binding and adduct formation of 7,12-dimethylbenz[a]anthracene in isolated rat mammary epithelial cells.',0 'The maximal (about 100-fold) stabilizing effect in concentrated solutions of salting-in agents was comparable with those induced by covalent modification with hydrophilic reagents or immobilization.',0 'No complications due to laparoscopy occurred.',0 '8 children, known to have been hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) positive for more than 6 months and with chronic active hepatitis on biopsy, received 2.5 mg levamisole/kg/day, 2 days a week for 6-18 months.',0 '[Aggregation behavior in cockroaches].',0 'In vitro transformation systems in experimental carcinogenesis: towards an integrated approach.',0 'The rate of target radical decomposition to become uncommitted damage that the cell may repair is affected by the concentration of oxygen (O2), thiols (S) and electronaffinic sensitizers (F), which compete with one another to form, respectively, target products TO2, TS and TF.',0 'The activity resides on a 232 bp segment with 5 binding sites for nuclear factor 1 (NF1), 2 for AP1, and 1 for steroid receptors.',0 'The emphasis is on a multi-disciplinary approach that involves co-divers and instructors, the rescue team, the police, forensic scientists, diving equipment suppliers, underwater physiologists and physicians, decompression chamber personnel, general practitioners, relatives and the forensic pathologist.',0 'Steroid sulfatase. Biosynthesis and processing in normal and mutant fibroblasts.',0 'Likewise, a substantial amount of NDF was apparently digested in the large intestine.',0 'Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms.',0 'Ninety asymptomatic shoulders of a comparable age had ultrasonography to serve as a control group.',0 'There was a strong association between methadone dose and heroin use; relative to a daily dose of 40 mg, a dose of 80 mg/day of methadone was less likely to be associated with a heroin-positive urine (OR 0.55, 95% CI [0.45, 0.68]).',0 'A comparative analysis between these neurons and the contiguous motoneurons of the VIIth nerve permitted differentiation of the two groups of neurons as to: distribution in a mediolateral direction, distribution in depth from the brainstem surface, longitudinal extension in the caudorostral direction and morphologic characteristics and dendritic arrangement of the neurons.',0 'Slow junctional rhythm was the most common rhythm disturbance found.',0 'Proposed causes of renal papillary necrosis (RPN) include tubular toxicity due to hyperconcentration of toxins in the renal medulla and vasoconstriction of medullary vessels with ischemic necrosis.',0 'While Ca2+ at 1 microM or more can generate high yields of inositol phosphates, guanine nucleotide activation of Gp can potentiate this Ca2(+)-dependent yield at resting levels of the cation.',0 'Adverse effects are rare and not severe.',0 'The mean serum levels of IgG, IgA and IgM in the epileptic probands were not significantly different from controls.',0 'At high ejecting currents (greater than 2-3 x threshold) the excitation was replaced by an inhibition.',0 'Only 4 (11%) patients showed acceptable hair preservation (no or minor alopecia).',0 'In an effort to elucidate the nature of the collagen-platelet interaction, the effects of collagen modification on platelet aggregation have been studied.',0 'Surgical exploration showed complete rupture of the tendon sheath of FCR in two cases, associated in the other two cases with complete rupture of the scaphotrapezial ligament.',0 'The erythrocytes sedimentation profiles (ESP) of normal blood and of blood mixed with saline, albumin (7%), and various molecular weight dextrans of different concentrations, at various height and widths of the sample holder are determined.',0 'Intracellular glutathione was maintained in the reduced state by the endothelium even during the oxidant stress caused by reoxygenation or the addition of peroxide.',0 'Initiation of lipid peroxidation in submitochondrial particles: effect of respiratory inhibitors.',0 'Ultrastructural immunocytochemical studies of the expression of major histocompatibility complex class I antigens in the placentas of inbred rats were performed using placentas derived from natural matings and from embryo transfers into females made pseudopregnant by mechanical stimulation.',0 'The purpose of this investigation was to provide load-deflection rate data for a variety of open and closed coil springs.',0 'If ASV or SFA caliber is marginal, consideration should be given to the use of a larger autogenous conduit, such as superficial femoral vein.',0 '[Damage to mandible induced by radiation therapy of intraoral cancer: a microradiographic study].',0 'Smoking behavior of younger smokers may differ from older smokers in ways important to the study of smoking motivation.',0 'During bronchoconstriction, the cough response was inhibited significantly as shown by the decrease in the number of cough efforts (p < 0.001), in maximum flow during inspiratory (p < 0.001) and expiratory (p < 0.001) movements and in the change of the expiratory (p < 0.01) and inspiratory (p < 0.01) pleural pressures.',0 'The cases comprised 329 CL wearers who were found to have lens related metabolic disorders, toxic or hypersensitivity reactions, cornea abrasions, microbial keratitis, or some other lens-induced problem.',0 'Keywords have been included with each reference to increase the value of the collection.',0 'The remaining one cyanogen bromide peptide (CB6) containing 109 amino acid residues was further digested with trypsin.',0 '[2 cases of extensive pharyngo-laryngeal tuberculosis].',0 'The main characteristics of Moschowitz syndrome and the most frequent causes of DIC are described in the discussion.',0 '[Goldenhar syndrome. Surgical emergency apropos of a case].',0 'We have developed a model of isochemic bowel necrosis in the rat by injecting platelet-activating factor (PAF) or PAF in combination with bacterial endotoxin.',0 'Since the available kinetic data are only in HIV patients, a study was carried out in normal volunteers, also with the objective of obtaining data on the biotransformation of the drug.',0 'A case of papillary cystic tumor (PCT) of the pancreas in a 55-year-old woman is described.',0 'S-R increased hepatic and adipose tissue lipid synthesis as measured by 3H incorporation.',0 'The conformational transition was monitored by measurements of the sedimentation coefficient, as was done by others earlier.',0 'It is suggested that plasma AVP and renal AVP receptors in SHR responded to the diuretic state induced by cilazapril by increasing the secretion and renal receptor affinity.',0 'Coping strategies varied depending on whether the women were at home or away from home and whether the women were alone or with others.',0 'Relation of eye color and gender to Type A scores and vocational preference.',0 'It was clinically noted that the cause of the increased intracranial pressure in this patient was enlargement of the cyst associated with ganglioglioma.',0 'After incubation for 80 min neither desipramine nor cocaine inhibited secretion.',0 '[Study of the family environment in attempted suicide during the developmental years].',0 '[Correction of blepharochalasis in 170 patients].',0 'The immunoreactivity (specific binding) of three Gly(A1)-sulfobenzoxadiazole-labeled insulins which have different spacer groups, Gly(A1)-[3-(4-sulfobenzoxadiazol-7-ylthio)propanoyl]-insulin , Gly(A1)-[2-(4-sulfobenzoxadiazol-7-ylthio)acetyl]-insulin, Gly(A1)-[3-carboxy-2(or 3)-(4-sulfobenzoxadiazol-7-ylthio)propanoyl]-insulin, toward an antiporcine insulin monoclonal antibody was investigated, where solid-phase fluoroimmunoassay technique was utilized.',0 'Effect of maternal ingestion of iophenoxic acid (Teridax) on protein-bound iodine: report of a family.',0 'Of neonatal deaths, 10.3% were stillbirth, 78.2% live birth and 11.5% undetermined.',0 'ConA, Suc.',0 'Since the bar-chromatin cells were much more frequent in patients with diseased eyes, we concluded that the findings were possibly of a regenerative nature.',0 'There was no increased risk of serious complications with decreased time from aspiration to transplant.',0 'The results show that, in contrast to ISDN, administration of 2-ISMN resulted in relatively high unchanged drug levels in the serum; the disposition of radioactivity after [14C]ISMN was however similar to that after [14C]ISDN.',0 'Neither human follicular fluid nor serum directly caused endothelial cell proliferation.',0 'The study was aimed at the assessment of frequency of occurrence of thyroid antimicrosomal and antithyreoglobuln autoantibodies in children with insulin-dependent diabetes and healthy control children.',0 'However, it attenuated and disappeared by 1 month after surgery.',0 'Fetal plasma carbonic anhydrase III and creatine kinase in Duchenne dystrophy.',0 'The cesarean section rate was 30.1 per cent.',0 'We present a clinical and cytogenetic report of one patient who has an interstitial deletion of 2, del(2) (p23p25.1), and a cytogenetic study of another cell line with an interstitial deletion of 2p (p23.1p25.1).',0 'The overall ratio of X- to Y-bearing sperm was 47% to 48.4% in the neat samples, and 48.4% to 45.3% in the swim-up fraction.',0 'Systemic disorders can often be recognized or suspected from chest radiographs.',0 'As part of a study of ulcer formation and healing, regeneration of colonic mucosa in rats was studied following placement of a surgical lesion.',0 'A large conductance K(Ca) channel in hippocampal neurons is also blocked by a number of putative Class III antiarrhythmic drugs, including tedisamil; thus, these agents may have utility in the characterization of the properties of K(Ca) channels in various cells.',0 'Evaluation studies on 4 per cent gelatin solutions for intravenous use. Excretion and retention of gelatin in relation to its molecular weight.',0 'Many studies on the enameloid with a long history show its character.',0 '[Ligature clamp-dissector].',0 'Isotope-specific analysis of Ni by ICP-MS: applications of stable isotope tracers to biokinetic studies.',0 'It was also shown that the survival rate of L3 cryopreserved for 28-321 days was also 96.2% and that, when 107 L3 frozen for 321 days were inoculated after being thawed into one jird, one live female adult was recovered at autopsy 71 days after inoculation, its morphology being the same as the unfrozen specimens.',0 'Ten day procaine penicillin therapy was not successful in the % 29.5 patients.',0 'Graft failure was documented through serum calcium determinations and histologic examination of the graft site.',0 'Treatment of human peripheral blood monocytes with staphylococcal exotoxin B and toxic shock syndrome toxin-1 resulted in a biphasic increase of IL-1 beta mRNA that lasted more than 12 h and in a more transient rise in TNF-alpha mRNA.',0 '[Subtraction method].',0 'Over a 20-month period, the numbers of both total respondents and eventual participants were recorded.',0 'This report is a review of the relevant recent literature and the tumors detected in our ultrasound unit between 1982 and 1988.',0 'Subjects underwent anthropometry to estimate muscle mass, spirometry to assess ventilatory capacity, a 30 s sprint on an isokinetic cycle ergometer to assess maximal leg muscle performance, and progressive cycle ergometry to assess overall exercise capacity.',0 'It has been claimed that the inorganic pyrophosphatase (PPase) of the plant vacuolar membrane transports K+ in addition to H+ in intact vacuoles (Davies, J. M., Poole, R. J., Rea, P. A., and Sanders, D. (1992) Proc.',0 'Immunotoxicity of low level cadmium exposure in fish: an alternative animal model for immunotoxicological studies.',0 'Surgery on the whole proved beneficial and it can be more rewarding if pre-operatively other causes of dyspepsia are either excluded or confirmed.',0 'Fifty isolates of Ascochyta rabiei (Pass.)',0 'After 3 weeks of DES treatment in rats with MtT/W15 tumor, there was an increase in growth hormone (GH)-producing cells and a decrease in PRL-producing cells when analyzed by the RHPA (control: percentage of GH, 36.3 +/- 6.2; percentage of PRL, 39.0 +/- 1.6 versus DES-treated tumors: percentage of GH of 68.2 +/- 1.9; and percentage of PRL, 3.2 +/- 1.8%).',0 'Stably integrated mouse mammary tumor virus long terminal repeat DNA requires the octamer motifs for basal promoter activity.',0 'I describe a novel catheter-based technique that may replace surgical myocardial reduction in some patients.',0 '[Functional gastrointestinal disorders].',0 '"Social awareness and the gold foil knife.',0 'The data suggest that these polypeptides could participate to the interactions observed in situ between microtubules and mitochondria.',0 'Comparison of myelography combined with postmyelographic spinal CT and MRI in suspected metastatic disease of the spinal canal.',0 'The results suggest that the increase in collateral coronary blood flow was in part a result of an increased transmural pressure gradient produced by balloon diastolic augmentation and the ability of mannitol to reduce coronary vascular resistance in ischemic myocardium.',0 'Results are discussed with reference to gender differences among adolescent sexual offenders.',0 'Undernutrition, defined in a child as weight less than 70% of the Harvard reference weight-for-age, was not associated with colonization, disease or the duration or severity of cholera.',0 'Paired measurements of PETCO2 by two infrared capnometers and a mass spectrometer were compared to PaCO2.',0 'Poison centers plight gets national attention.',0 'Shaded three-dimensional computed tomographic display proved most useful in demonstrating this complicated osseous anomaly.',0 'The bacterial counts were similar in wounds dressed with CS, PU, or PTFE.',0 'The effects of stimulation of the basolateral amygdalar nucleus were excitatory as well as inhibitory.',0 'The bactericidal action is assumed to be due to direct effects of high electric fields.',0 'Syrian hamster lymphotoxin increased the synthesis of high molecular weight (50,000-250,000) membrane glycoproteins in non-tumorigenic secondary passage NIH/N Syrian hamster embryo fibroblasts and caused a decrease in the synthesis of high molecular weight glycoproteins in benzo[a]pyrene-induced hamster tumor cells.',0 'The results of this study show that a dangerous increase in BP and HR with increased myocardial oxygen consumption can be prevented by a single bolus, and better by a double bolus of 100 mg esmolol.',0 'These constructs should be valuable in analyses of the structure-function relationships of fibronectins.',0 'Luminol-enhanced chemiluminescence (CL) was used to measure the production of reactive oxygen intermediates (ROI) generated by oyster hemocytes using zymosan as a stimulant.',0 'We detected the HBV DNA in peripheral blood monocytes of 70 patients with chronic hepatitis B and 20 healthy controls by polymerase chain reaction (PCR) and Southern transfer hybridization technique, the HLA-DR expression on monocytic membrane and tumor necrosis factor-alpha (TNF alpha) content and interleukin 1 (IL 1) activity in their monocytic culture supernatant were also measured respectively by indirect immunofluorescence technique, ELISA, and thymocytic multiplication assay.',0 'Acute hemodynamic effects of MDL 19205 in mild congestive heart failure.',0 'Intakes of B vitamins, phosphorus, and potassium were adequate, with few ethnic or socioeconomic differences.',0 'A kininogenase resembling glandular kallikrein was partially purified from vascular tissue and characterized.',0 'The large pVM82 plasmid isolated from epidemic strains of Yersinia pseudotuberculosis includes the 25MD segment, which encodes a series of properties affecting the virulence of the bacterium.',0 'Our results show that: (a) cholesterol decreases the electron spin-lattice relaxation time Tle of 14N-16 doxyl stearate spin label in dimyristoylphosphatidylcholine (DMPC) and egg yolk phosphatidylcholine (egg PC).',0 'From these results, it is concluded that the theoretical formulation for the survival fraction of bacteria can afford a quantitative method for analysis of the repair process for radiation-induced single-strand breaks in DNA in vivo.',0 'NodP appears to be the smaller subunit of ATP sulfurylase.',0 'Nitroimidazoles and imaging hypoxia.',0 'The significance of trisomy 7 mosaicism in chorionic villus cultures.',0 'Arteriovenous aneurysms of the posterior fossa.',0 'Dose equivalent ceiling is close to the quantity measured by existing instruments, is both additive and measurable, and can be rigorously related to primary radiation field quantities.',0 'Ca2+ and Ca2+-activated K+ currents in mammalian gastric smooth muscle cells.',0 'Thirteen tumors (4.5%) had a copy number of 5 to 10.',0 'Cimetidine and obstetric anaesthesia.',0 'The neuroleptics added to the incubation mixture in vitro inhibited IMI hydroxylation noncompetitively.',0 'Using the example of psychosomatic diagnosis, I argue that the clinical context has unique epistemological constraints that limit the certainty of diagnosis and so make meaning indeterminate for sufferer and healer.',0 'Isomers 2a and 2b were readily epimerized under acidic or basic conditions or under conditions used for gas chromatographic analysis.',0 'Similarly, patients with serum transferrin levels above 150 mg/dl had significantly fewer wound problems (P less than 0.01).',0 'Under these conditions, however, noradrenaline was still able to inhibit insulin secretion maximally.',0 'Four-week ditec course induced no considerable changes in bronchial permeability, but increased reversibility of bronchial obstruction, inhibited sensitivity and response of the bronchial tree to acetylcholine.',0 'Total tract digestibilities of total C18 fatty acids and total fatty acids were greater (P = .01) for roasted soybeans than for raw soybeans (88.0 vs 82.4 and 86.3 vs 81.0%, respectively).',0 'Photosensitivity was not present.',0 'Predominant involvement of mu-rather than delta- or kappa-opiate receptors in LH secretion.',0 'In the next step, concrete features of sequence entities in terms of occurrences of smaller subsequences are identified at various positions which are used as a knowledge base to select potential functional entities from the identified like sequences.',0 'Heterogeneity in the oligodendrocyte population was indicated by the observation that some cells respond to both GABA and glutamate, while others respond to only one and some are not responsive to either.',0 'In half of the remaining 18 cases the serial LH levels exhibited a decrease, as well as the physiological pulsation disappeared.',0 'In contrast, responses induced by other directly acting mediators (bradykinin and histamine) and responses induced by PMN leukocyte-dependent mediators (C5a des Arg, N-formyl-methionyl-leucyl-phenylalanine, and leukotriene B4) were not suppressed.',0 'The myeloid specific enzyme myeloperoxidase belongs to this group of genes.',0 'All tumors were non-reactive for human Papillomavirus antigen and HIV p24 antigen.',0 'The group of medically examined weavers was divided into three parts: Cr.',0 'Phenotypic expression of the 47,XYY chromosome complement in man has been investigated mostly in terms of the central nervous system.',0 'Isoelectric focusing in liquid column separated two unspecific thiol esterase components with S-lactoylglutathione (pI = 8.4) and S-propionylglutathione (pI = 8.1) as the best substrates, respectively, and two specific enzymes, S-formylglutathione hydrolase (pI = 5.2) and S-succinylglutathione hydrolase (pI = 9.0).',0 '[Manipulation of composite restorative materials in dental practice].',0 'The post mortem revealed an encephalitis and a sepsis although splenic regenerates were found in the omentum pouch.',0 'Four children had transient contact with the source patient as he entered or exited through the waiting room; only one of the four had face-to-face contact within 1 m of the source patient.',0 'Results of using the Smith-Robinson approach for herniated and extruded cervical discs. Technical note.',0 'Enhanced transformation of mouse 10T1/2 cells by 12-O-tetradecanoylphorbol-13-acetate following exposure to X-rays or to fission-spectrum neutrons.',0 'This statement must be related to the position of the carpal bones, which do not show any significant change despite the tears shown.',0 'In relation to immunology, enzymology has the advantage of being suitable for use during periods at which bacteriological examination of the urine is negative, and hence is useful in following the influence of treatment.',0 'We found that 18 (66.7%) out of 27 patients with facial palsy showed a nasal cycle and that 9 (33.3%) showed no nasal cycle.',0 'The effect of three solutions on postoperative pain relief by continuous epidural infusion was studied.',0 'Second, attempts were made to determine the accessibility of the fibre ends in the penton structure by ELISA assays and by immunorevelation of penton in Western blots.',0 'Trimethoprim and pyrimethamine were found to be weak inhibitors (ID50 = 39,600 and 2,800 nM, respectively), while methotrexate and trimetrexate were potent reductase inhibitors (ID50 = 1.4 and 26.1 nM, respectively).',0 'Repeated amphetamine (AMPH) administration into the nucleus accumbens does not enhance (sensitize) the locomotor activity produced by a subsequent systemic AMPH challenge.',0 'This further underlines the similarity between this phenomenon and the Diffuse Noxious Inhibitory Controls (DNIC) described in the rat, since the latter are observed in intact but not in spinal animals.',0 'Decreased motor-coordination, and increased pain-responding times may indicate development of peripheral neuropathy in addition to muscle weakness.',0 'Comments on mutagenesis risk estimation.',0 'These studies showed that ACE-inhibitors could prevent the incidence of heart failure in about one-third of patients with severe left-ventricular dysfunction during 3 years of observation when compared with placebo treated patients.',0 'Bile salts also caused increased release of glycoproteins from explants of guinea pig gastric antrum and colon.',0 'Thus protection against infarct-related VF by TxB2 inhibition is a property shared by more than one pharmacologic agent.',0 'Studies on carcinogenic bifunctional aminoazo dyes. IV. Progressive microscopic alternation in the livers of rats fed the carcinogenic bifunctional aminoazo dyes: (N, N-dimethyl-4-amino)-N-acetyl-N-monomethyl-4-aminoazobenzene.',0 'Multiple primary cancers involving the breast.',0 '41 active and 9 passive fixation electrodes were utilized.',0 'The antilipolytic hormonal factors, prostaglandin E1 (1 micro M), N6-phenylisopropyladenosine (1 micro M) and nicotinic acid (30 micro M) reduced both basal and cholera toxin-stimulated enzyme activities.',0 'Search every available resource for children with handicaps.',0 'These results suggest that local administration of cyclosporin may be useful for certain grafts.',0 'Preparation and choice of anaesthesia are discussed.',0 'In agreement with others we would thus conclude that LGL embrace the majority of NK-effector cells.',0 'The amino-acid sequence of the hemoglobin of the Dogfish Shark (Squalus acanthias) is presented.',0 'Further, one-dimensional peptide maps of the hamster smooth muscle 10 nm filament protein and the hamster fibroblast 52,000-dalton protein are identical to one another and distinct from the peptide maps of both the 42,000- and the 55,000-dalton components of the fibroblast cytoskeletal preparations.',0 'The formation of glycosylamines rather than the more popular reductive amination has been used to label the reducing end of sugars with ultraviolet or fluorescence tags.',0 'Sexual differences in the action of vitamin E on the bioelectric activity of duodenal smooth muscles were discovered.',0 'The mean number of intralobular CD3+ and CD8+ cells and the mean serum ALT level decreased significantly in chronic viral hepatitis C patients (p less than 0.05) but not in chronic viral hepatitis B patients.',0 'Basal ANF and ACTH concentrations were determined in the plasma with specific radioimmunoassays over a 30-min observation period.',0 'Studies on the receptor mediating cyclic AMP-independent enhancement by adenosine of IgE-dependent mediator release from rat mast cells.',0 'These bactericidal activities were compared with those of methicillin, cefazolin, cefamandole, cefuroxime, ciprofloxacin, and vancomycin.',0 'These properties, which characterize the quantal events on the basis of spontaneous synaptic activity, were strikingly similar to those of the basic units derived by the simple binomial to those of the basic units derived by the simple binomial analysis of unitary postsynaptic potentials, thus validating the use of this statistical model to quantify the quantal nature of release at central connections.',0 '[Unusual case of foreign body in the orbital arch and in the temporal region].',0 'History of the regional dental clinical examinations.',0 'The feasibility, practicability and rapidity of the test make it a test of choice for rapid diagnosis of influenza A.',0 '[Strangulation of a portion of the ileum with a ligature in a newborn infant with an embryonic umbilical cord hernia].',0 'Discordance between male and female deaths due to the respiratory distress syndrome.',0 'Therefore, the native CuZn-metallothionein must contain separate populations of molecules with Cu distributed differently.',0 'Transplantation of adenomatous polyps, normal colonic mucosa and adenocarcinoma of colon into athymic mice.',0 'DNA sequences containing the 5-flanking regions of the insulin and chymotrypsin genes were linked to the coding sequence of the chloramphenicol acetyltransferase (CAT) gene.',0 'Cholestasis may be extra or intrahepatic.',0 'These values were compared with the observed averages in amniotic fluid of 4.7 and 4.6 mEq/liter in the deficient and control groups, respectively.',0 'A clear tendency was evident for horses that had the highest serum cytotoxicity (RGI less than 75%) to also have clinical profiles suggestive of endotoxemia.',0 'In senile cataract certain characteristics of the native three-dimensional structure of gamma- and beta-crystallins are completely lost, whereas during dehydration of lens tissue a small but significant contraction of these protein molecules takes place.',0 '[Lymphomas of the skin].',0 'The nature of many of the abnormalities found in mutant feathers suggests a common source in defective embryonic mesoderm.',0 'First, using incidental memory tasks, subjects (N = 164) with a right side seating preference (i.e., to the speakers left side) were found, in their test-taking behavior, to respond more positively to inaccurate distractor words (Experiments 1 and 2), particularly those with an ambiguous semantic reference (Experiment 3).',0 'The hypercalciuric group of patients was further subdivided using two previously published methods for identifying hyperabsorbers--one based on fasting urinary calcium/creatinine ratios and renal threshold phosphate concentrations, Jongen and the other method based on an oral calcium load test, Pak et al.',0 'Synacthen depot used in general practice.',0 'The phosphorylation of the 27 K-protein was not seen in the homogenate of the NGF-treated cells.',0 'The identification and the education of a pediatric neurosurgeon at an international level.',0 'Some progeny from some crosses were more resistant to hygromycin than were their sibs or the transformant strains that served as their parents.',0 'Fundal findings in a female carrier of X-linked ocular albinism.',0 'The ratio of fluorescence intensities at two polarization modes of the incident light (the transverse magnetic and the transverse electric polarization mode, respectively) gives a relation between the orientation angles of the porphyrin relative to the interface.',0 'These phenotypic modulations could be indirectly driven by cytokines in a paracrine or autocrine fashion.',0 'Similar glucocorticoid receptor sites and binding affinities were observed in T24-NIH-3T3 or TPA-treated NIH-3T3 cells compared to wild-type untreated cells.',0 'Neither ovariectomy nor ovariectomy with estradiol replacement brought about any change in the NMDA receptor mRNA levels in the hypothalamus.',0 'This study investigated this new technique for the diagnosis and localization of vascular graft infections.',0 '[Debate problems of the treatment of open fractures of long tubular bones].',0 'Receptor densities were quantified by in vitro autoradiography using the tritiated antagonists spiperone (D2) and SCH23390 (D1).',0 'Surgical rates in the United States: 1966 to 1978.',0 'Branched, struvite calculus and clear cell carcinoma in same kidney. Rare condition with significant implications for management.',0 'Evolution of the healing room.',0 'Granulosa cells harvested from pregnant mares serum gonadotropin treated immature rats were incubated in the presence and absence of the divalent cation ionophore A23187.',0 'Twenty-five patients underwent consecutive studies during their evolution.',0 'Complete resolution of abscesses on CT scans rarely occurred during hospitalization and took as long as 5 months.',0 'It is hypothesized that such disturbances are not created by sedimentation of the growing polymer chains in the gravitational field, but are produced by the reaction exothermality, which produces strong buoyancy-driven flows.',0 '[Drinking water of Madagascar from 1959 to 1977 (20,465 bacteriological analyses)].',0 'DSM-III diagnoses were made by consensus of two investigators.',0 'All three clone types were able to activate B cells as shown by up-regulation of CD25, CD80 and CD86 expression.',0 'Effects on plasma vitamin A levels were also found, but these were less clear.',0 'Chronic treatment with diazepam or the inverse benzodiazepine receptor agonist FG 7142 causes differential changes in the effects of GABA receptor stimulation.',0 'Properties of a delta 5-fatty acyl-CoA desaturase in the cotyledons of developing Limnanthes alba.',0 'The rate setting can be arranged such that an emission maximum is produced 30 to 40 s after mixing the sample with the light-yielding solution, hence providing for a convenient analytical performance.',0 'Up to 15 Hz the eye movements corresponded to the alternating pressure stimulus upon the fistula.',0 'Convulsions induced by these drugs lead to differential patterns, such as clonus, myoclonic or tonic seizures.',0 'This issue was examined in 3 nativity cohorts from a population of 766 black prenatal clinic patients in New York City using a series of stepwise hierarchical multiple regression analyses.',0 'Ultrafast computed tomographic (CT) evaluation of the airway can be performed with either 50-msec low-resolution images (cine CT) or 100-msec high-resolution images (high-resolution CT).',0 'LVP had a strong just opposite effect.',0 'Good results were obtained in 60 (70%) after one surgical procedure and in 18 (21%) after two operations.',0 'Antitumoral activity of alkylphosphocholines and analogues in human leukemia cell lines.',0 'Autopsy studies have shown that atherosclerosis begins in childhood with the appearance of aortic fatty streaks.',0 'A characteristic of 1358 is that the L and S components are frozen in one (prototype) orientation.',0 'Tumor extension was demonstrated preoperatively with sonography and computerized tomography.',0 'ANP, BNP, and CNP are distributed in discrete brain regions, although the distribution varies in different species.',0 'We address two issues concerning the largely unexplored area of polymerase dynamics: (i) The validity of an approximate kinematic formula linking rf and rt suggested by experiments in which transcription is inhibited in some prokaryotes with the antibiotic streptolydigin, and (ii) What are the molecular bases of the kinematic formula?',0 'The rate of extracardiac malformation (ECM) associated with congenital heart disease (CHD) is high in neonates.',0 'Supine systolic blood pressure was decreased significantly after ramipril (F = 11.16, p less than 0.01), but diastolic blood pressure was not.',0 'All dietary treatment groups exposed to hyperoxia had a similar increase in lung:body weight ratio, but none of the hyperoxia-exposed rats had MRI-detectable lung damage.',0 '[Clinical, diagnostic and therapeutic aspects of hyperprolactinemic states].',0 'In contrast, CHX inhibited, but failed to completely block, the Con A- and Con A+PMA-induced IL-3 mRNA expression, whereas the expression of both genes was completely blocked by cyclosporine A. With regard to the secretion of IL-4 protein it was shown that it closely follows the accumulation of IL-4 mRNA.',0 'Physicians knowledge of automobile safety seats.',0 'The adaptive difficulties experienced by Offers tumultuous group of adolescents were once considered normal problems for that age group.',0 'Additionally, in Experiment 2, a measure of masticatory pressure was employed to assess the intensity of chewing and to empirically verify the number of chews.',0 'We used this labeled arylsulfatase A (specific radioactivity 4-7.5 Ci/g) together with nonlabeled enzyme and rabbit antiserum produced against homogeneous enzyme to develop a radioimmunoassay for arylsulfatase A in urine.',0 'Delta-sleep-inducing peptide, a humoral sleep factor, also seems to affect circadian rhythms.',0 'Furthermore, physicians must avoid contracts which will result in the uncontrolled growth of a practice beyond its capabilities for expansion.',0 'Skin hypersensitivity to parainfluenza-3 virus in cattle.',0 'This progression may be facilitated by the ready availability of heroin and the local tradition of smoking or inhaling rather than injecting opiates.',0 'Melanin has been previously shown to modify the mydriatic response to atropine instillation.',0 'In the preventive test, naproxen strongly inhibited granuloma formation and exudate accumulation as did indomethacin and prednisolone.',0 'The fractional flow from AMP to inosine through adenosine was estimated by the use of the adenosine deaminase (EC 3.5.4.4) inhibitors, coformycin and 2-deoxycoformycin.',0 'No such trends were found in correlations between performance and agency beliefs for luck or for unknown causes.',0 'FFA levels were reduced by 65% in each group in response to refeeding.',0 '[Utilization of guide lines and manuals for dental hygiene].',0 'Electrosurgical dissection to reduce blood loss in head and neck surgery.',0 'A blood sample was obtained from each sow between 19 and 23 days after estrus (first day of estrus = day 1) and again between 26 and 30 days and was analyzed by radioimmunoassay for content of progesterone and estrone sulfate, respectively.',0 'This amino acid change matched with that reported in Hb M-Saskatoon.',0 'In dithioerythritol extracts at pH 9 the major component of the crystal is the protein with molecular weight 120000--140000 (component B).',0 'RESULTS : The dose-response relationship for carcinogenesis of chloral hydrate and other chemicals in its metabolic breakdown pathway is nonlinear in rodents: very high doses given chronically, sufficient to cause cellular necrosis, are necessary for induction of malignancies.',0 'Blocking of the alpha-adrenoreceptors with phentolamine induced a reinforcement of the contractile reactions, whereas blocking of the beta-adrenoreceptors with propranolol led to inhibition of both jejunum and ileum contractile responses either to exogenous acetylcholine or electrical stimulation of vagal efferent fibers.',0 'At 6 months, 5 (38%) of the 13 were independent, 2 (15%) were dependent (severely disabled), and 6 (46%) had died.',0 'We report 7 cases of neurosyphilis observed over a 13-month period in a Parisian University Hospital.',0 'Properties of the uterine enzyme were similar to reported values for lysosomal hexosaminidase.',0 '[Influence of personality factors on the success of psychopharmacotherapy].',0 'The ipsps were partially blocked by 0.2-0.5 microM strychnine and were completely blocked by 5 microM strychnine.',0 'Each alternative reflects negatively on cimetidine as an antiulcer medication; however, confirmation of adverse effects would force radical review of most current therapy of ulcer disease.',0 'Cerebellar inhibition of the vestibulo-ocular reflex in rabbit and cat and its blockage by picrotoxin.',0 'Analysis of correlations and regressions has revealed reliable relationships between plasma fibronectin levels and clinical values of the intensity of reparative processes at the site of surgery.',0 'Prediction of haemorrhagic diathesis in thrombocytopenia by mean platelet volume.',0 '(2) The vestibular nuclei are very intensely positive for 5-nucleotidase but exhibit variable activity of alkaline phosphatase.',0 'Inspiratory EMGgg was only present above a PCO2 threshold, which was similar for each state (49.3 +/- 2.3 mm Hg PETCO2 awake, 48.8 +/- 2.4 during NREM, 49.5 +/- 2.5 during REM), and delta EMGgg/delta PETCO2 tended to be less during both sleep states compared with that while awake (p = 0.10).',0 'Multivariate logistic regression analysis in the patients with MR revealed that the strongest predictor of postoperative EF was preoperative EF (p less than 0.001).',0 'The above spezified dilutions correspond with 5 microliters, 0.5 microliter, 0.05 microliter and 0.005 microliter of blood, respectively.',0 'All were examined with the FE sequence and Gd-DTPA as a contrast medium.',0 'An interpretation of strains JEV73 and JEV73R as regulatory mutants of strain AT2046 is given.',0 'Trisaccharides, GlcNAc-GlcUA-aMan and GlcNAc-IdUA-aMan, were released from the nonreducing end of HS-oligosaccharides by deaminative cleavage.',0 'Long-range mapping was facilitated by the presence of several sites for rare cutting restriction endonucleases in the 5 region of N-myc.',0 'Two mutations in the sodium channel alpha subunit that have been implicated as the cause of periodic paralysis were studied by functional expression in a mammalian cell line.',0 'ACE inhibitors have been studied for their use in the prevention of ventricular remodeling and reduction in postinfarction mortality.',0 'Health care providers should continue to stress the use of barrier methods to all sexually active adolescents.',0 'The epidermal nevus was not associated with any abnormal pilosebaceous complexes.',0 '[Physiopathology of bronchial asthma. Current data].',0 'Patients who experienced problems during MRI had pre-imaging anxiety levels equivalent to patients about to undergo surgery, were more likely to react badly when first seeing the scanner and were more likely to leave the MRI unit with even greater feelings of anxiety than when they arrived.',0 'WHR did not correlate with BP in either sex, but waist and hip measurements correlated significantly with BP in both sexes.',0 'These findings are discussed and it is suggested that some local factor maintains the dominance of one horn and that this factor may be related to the local influence of the placenta.',0 'The preoperative diagnosis of perforated Meckels diverticulum was not made in any of the cases.',0 'The progression of pneumonia was more rapid in group 2.',0 'Large plasma proteins are retained in the subendothelium by the size-restrictive water-filled channels of the lamina densa and accumulate upstream in the form of hyaline which eventually occludes individual loops.',0 'The epidemiology of prescribing in an urban general practice.',0 'Various nonosseous tumors in mice and rats concentrate gallium-67-ESR-586 preputial gland carcinoma, P-1798 lymphosarcoma, C3H/ HeJ mammary tumor, AKR/J thymic lymphoma, R-3259 giant cell sarcoma, Walker-256 carcinosarcoma, and a new transplantable neoplasm of rats.',0 'Multiple regression analysis revealed the effects of diet per se on growth to be fairly minimal; a maximum of 28 per cent of the variation in growth could be explained by diet and the few individual nutrients significantly correlated with a growth index were not consistent.',0 'Changing the internal medicine residency.',0 'In Cardiff, 86 283 total births between 1965 and 1979 included 139 infants with oral clefts.',0 'The explanation for the different rates of progression in individual patients is not understood.',0 'Information was obtained by personal interview of the probands.',0 'The luminal mucus layer of the rats small intestine was separated from the mucosa by filling the lumen with agar jelly.',0 'We conclude from these data that the 188,000-mol wt molecule is a precursor of the C3b receptor of HL-60 cells.',0 'DEX treatment also had the effect of delaying and attenuating the nocturnal peak; mean GH secretion between 0000-0200 h was significantly greater before DEX (13.6 +/- 2.7 micrograms/L) than after DEX (3.6 +/- 0.7 micrograms/L; P less than 0.001), whereas that between 0300-0800 h was greater after DEX (5.5 +/- 0.8 vs. 0.7 +/- 0.2 micrograms/L; P less than 0.001).',0 'CONCLUSIONS : The spectrum of mutations defined forms the basis for a beta-thalassaemia prenatal diagnosis programme in India.',0 'Reed-Sternberg and mononuclear Hodgkins cells were consistently negative for fibronectin.',0 'These results, together with data from other studies, suggest that the total Mg(2+)-ATPase activity in the membrane represents at least two separate enzymes.',0 'Fifty-nine percent of the units showed low mean endotoxin levels (i.e. mean concentration below the recommended limit in Sweden: < 25 ng l-1), while 18% of units had high levels (mean concentration > 100 ng l-1).',0 'Only one infection and no paralysis or death occurred in the 186 patients.',0 'Baseline plasma renin activity (PRA), concentrations of aldosterone (PA), atrial natriuretic factor (ANF), and norepinephrine, and urinary electrolyte excretion were also comparable in the two subgroups.',0 'The cell extract contained mainly a heparan sulphate proteoglycan that has a buoyant density of 1.31 g/ml and a protein core with apparent molecular mass 300 kDa.',0 'Pharmacokinetics of gentamicin after intravenous and subcutaneous injection in obese cats.',0 'Chest pain, risk factors and coronary artery disease.',0 'PBMC from individuals with acute visceral leishmaniasis responded to stimulation with leishmania lysate by producing IL-10 mRNA.',0 'However, this slope can only be predicted with less than 5% error if the correlation coefficient is very high (i.e., above 0.99).',0 '[Prevention of endemic goiter. Notes on current methods].',0 'The lowest liver Cd levels of the Cd-polluted subjects with renal damage were around 30 micrograms/g.',0 'These smaller abdominal aortic aneurysms were in patients younger than the operated probands (average age men, 67 years; women, 69 years).',0 'From the histologic point of view, the number of metastatic nodes was 1 in 13 patients, 2 to 3 in 10 patients, and 4 or more in 23 patients; the number of metastatic nodes was not evaluable in 14 cases.',0 'There is accelerated destruction of non-parasitised erythrocytes in severe malaria resulting in a mean MCL that is half that found previously in healthy Thai volunteers (89.6 +/- 13.1 days, p less than 0.001) and significantly shorter than that reported previously in Thai patients with uncomplicated P. falciparum infections studied after parasite clearance (56.8 +/- 10.2 days, p less than 0.05).',0 'Ileal dysfunction and bile composition in children.',0 'In one region, four basic residues (K-736 R K R) played a critical role in the nuclear translocation of PB2, since the deletion or mutation of these residues rendered the protein totally cytoplasmic.',0 'Reactivity patterns of other monoclonal antibodies with lymphocytes from patients with ALL did not clearly define groups of ALL patients.',0 'One patient described worsening of her incontinence and underwent a Marshall-Marchetti-Krantz procedure three months postoperatively.',0 'Many of the antisera proved to be polyspecific despite absorption procedures.',0 'Reversal of gelatin-impaired wound healing in rats by exogenous fibronectin.',0 'Congenital bilateral cataract and search nystagmus were found in all of them.',0 'Low concentrations of 5-HT (10(-7) g/ml.)',0 'The second pool of material which was soluble in EDTA showed a smear on SDS gel electrophoresis while the third pool consisted of the insoluble matrix.',0 'When Lip-PGE1 treatment was given both before and 2.5 h after IL-1 alpha administration, lung leak was decreased to baseline levels.',0 'Renal angioscintigraphy and captopril renal scintigraphy were performed in accordance with renal arteriography in 80% of patients.',0 'Prostaglandins and the pulmonary circulation.',0 'Flower-enhanced expression of a nuclear-encoded mitochondrial respiratory protein is associated with changes in mitochondrion number.',0 '[Dynamics of non-specific serologic reactions in infectious hepatitis].',0 '"The orthodontic skill mix in Sweden.',0 '[The Moscow Military Hospital in the War of 1812].',0 '[Effect of thyroxine on the transport of free and esterified cholesterol into the arterial wall].',0 '[Prospectives of the development of the pharmaceutical newtork and improvement of drug provision for the population].',0 'Special article to the graduating class of 1993, John A Burns School of Medicine.',0 'ACTH was significantly increased following the 1200 hr and 1600 hr meals with the high protein diet.',0 'Fifteen per cent of primary first episodes were caused by HSV-1, as compared with 3 per cent of nonprimary first episodes and 2 per cent of recurrent episodes.',0 'On the basis of the obtained results the metabolic availabilities of these vegetable tissues are discussed.',0 'An improved negative immunomagnetic selection strategy has been devised for the enrichment of primitive hemopoietic cells using the high proliferative potential colony-forming cell (HPP-CFC) assay as an index of stem cell purification.',0 'CONCLUSIONS : Parainfluenza virus is a cause of serious lower respiratory tract involvement in both adults and children who undergo bone marrow transplantation.',0 'Simultaneous administration of 5 micrograms PTH and 5 micrograms CT at maximal stimulatory doses produced additive effects, indicating the presence of separate receptor sites for PTH and CT in the bone.',0 'S-100 protein was demonstrated in 28/31 melanoma tissue sections that had been previously stained by hematoxylin and eosin, including 17 from 19 primary melanomas and 11 from 12 metastases.',0 'None of the cell free filtrates from strains derived from normal sacs showed any evidence of toxin production.',0 'The sixth antibody reacted with 32 of the 37 cells tested.',0 'Expression of human alpha-fetoprotein in yeast.',0 '[A new test of activity of antilymphocyte serums: inhibition of the rosette phenomenom].',0 'Indirect fluorescent antibody test (IFAT) was performed by the method of [symbol: see text] (1971) with some slight modifications for the diagnosis of amoebiasis.',0 'Determination of p-hydroxyphenoxyacetic acid in phenoxymethyl penicillin fermentations.',0 'However, in one of four retinas examined, a large number of RGCs seemed to survive axotomy, and among these, beta cells survived at an unusually high rate.',0 '[Angiography of lesions of peripheral soft tissues].',0 'Encouraging the highest quality in endodontic education.',0 'Recipient nuclei acquired 9 of the 10 chromosomes examined, with frequencies which were inversely correlated with the size of the chromosome.',0 'In Ca(2+)-containing solutions, depolarization led to a rebound increase in pHi above control.',0 'After 12 h, the PCCG content had increased by a factor of 7.',0 '[Correction of defects of dental arches in the prevention of maxillofacial anomalies].',0 'The enzyme activity in the membranes was inhibited by acetazolamide, furosemide and KSCN.',0 'Antihypertensive efficacy of alpha-methyldopa, chlorothiazide and Supres-150 (alpha-methyldopa-chlorothiazide).',0 'Acoustic determinants of perceptual center (P-center) location.',0 'Analysis and sorting of live cells according to secreted molecules, relocated to a cell-surface affinity matrix.',0 '[Letter: Myoclonic encephalopathies caused by bismuth salts].',0 'Patients admitted to a district general hospital for general surgery were examined on admission and at weekly intervals for carriage of Staphylococcus aureus and coagulase-negative staphylococci (CNS) in the anterior nares.',0 'Skeletal lead-210 as an index of exposure to radon decay products in mining.',0 'Inflammatory or noninflammatory processes and traumatic disorders all may be well assessed by magnetic resonance imaging, particularly articular disorders or marrow and surrounding soft-tissue lesions.',0 'These results suggest a possible mechanism for toxic side effects of CPZ in man such as granulocytopenia and light sensitization.',0 'Quinidine prolonged the PR intervals from 160 +/- 14 ms to 183 +/- 26 ms, but procainamide, disopyramide, and mexiletine did not change the PR interval (P less than 0.005).',0 'Men who presented with primary HSV proctitis had a lower prevalence of HIV antibody than those with preexisting HSV-2 antibody (44% vs 68%); this suggests that HSV-2 infection antedated HIV infection.',0 'RESULTS : A comparison of data obtained in the laboratory with measurements during public transportation proved that in tram, bus and tube, the jerk and the level of acceleration are both in principle unmanageable without extra support.',0 'A male infant, partially trisomic for a small segment of chromosomes 6 and 22 resulting from a maternal translocation, is described.',0 'CONCLUSIONS : This study shows that both treatments are effective and well tolerated; more patients given cyclophosphamide had stable remissions.',0 'Immunosuppressive effect induced by Actinobacillus actinomycetemcomitans: effect on immunoglobulin production and lymphokine synthesis.',0 'Thirty-four (20%) of those evaluated underwent laparoscopy, of whom 31 (91%) were found to have ectopic pregnancies.',0 'Dose-response curves demonstrated a close relationship between the inhibitory effects of DXS on the DTH and the A-PE/DDA complex formation.',0 'In three of these cases enhancement within the musculature was seen following i.v. administration of Gd-DTPA on T1W images.',0 'Sonographic diagnosis of primary muscular echinococcosis.',0 'Motilin levels were within the normal range, and fluctuations correlated with the occurrence of an AF.',0 'The inhibitory responses generated by the endothelial cells are not all mediated by identical cellular events.',0 'Tyrosine phosphorylation of the tyrosine kinase JAK-2 and activation of STAT proteins were dependent on box 1 and sequences within 63 amino acids of the plasma membrane.',0 '[Use of implantable pacemaker in the treatment of paroxysmal supraventricular tachycardia refractory to pharmacologic therapy].',0 'NDGA-induced inhibition was not reversed by indomethacin or SKF525A, alone or in combination, precluding arachidonate shunting into other pathways.',0 'High-resolution magnetic resonance imaging evaluation of blood-retinal barrier integrity following transscleral diode laser treatment.',0 'The development of the embryos was somewhat faster in vivo than in vitro.',0 'A retrospective study of 66 biopsies of pemphigus revealed that one third of them comprised histological signs of PNP; one of the corresponding sera reacted with mouse bladder epithelium.',0 'After therapy, H. pylori was eradicated and the clinical manifestations faded.',0 '2-Fluoroformycin, although a much poorer substrate for adenosine deaminase than formycin A, is not nearly as cytotoxic to cells in culture.',0 'Prediction of success in medical school.',0 'Scientific basis for assessment of biocompatibility in extracorporeal blood treatment.',0 'Nerve fibres showing CGRP-immunoreactivity were exclusively distributed around blood vessels in the periodontal ligament of normal teeth.',0 'Nifedipine and verapamil decreased resting Ca levels by up to 35-40%.',0 'All patients with involvement extending above the common iliac bifurcation died within a short time, as did all those with prostatic involvement.',0 'Oncogenes and avian development.',0 'There was a significant decrease in articular amplitudes with age and a considerable increase of arthritis especially after 70 years.',0 'The goalkeepers were significantly heavier (86.1 +/- 5.5 kg; P < 0.01) than all groups except the centre-backs, had significantly higher estimated body fat percentages than centre-backs, forwards, midfield players (P < 0.01) or full-backs (P < 0.05), significantly lower estimated VO2 max values (56.4 +/- 3.9 ml kg-1 min-1; P < 0.01) and were slowest over 60 m (12.71 +/- 0.42 s).',0 'The two pesticides Zineb and Ziram, belonging to this chemical class, induced an increase in single-strand DNA breaks, as measured by the alkaline elution technique.',0 'The effects of AMZ on hippocampal kindling were not assessed.',0 'The polycation caused increase in PG synthesis appears to be the result of increased availability of intracellular C20:4.',0 'Of 42 patients with dissection of the aorta, 4 had important arch involvement.',0 'For example, many basic stem cell concepts were established using CFU-S as a paradigm.',0 'Sedimentation in a preparative ultracentrifuge was used to determine the affinity of heavy meromyosin, HMM, for regulated actin, F-actin plus troponin-tropomyosin, in the presence of MgATP at pH 7.0, 20 degrees C, and mu = 18 mM.',0 'We investigated the effects of bile salts on release of radiolabeled glycoproteins by explants of guinea pig gallbladder in organ culture.',0 'A large portion of the 13C resonance assignments for murine epidermal growth factor (mEGF) at pH 3.1 and 28 degrees C has been determined at natural isotope abundance.',0 'Sodium nitroprusside (NP) caused both an inhibition of a noradrenaline (NA)-induced contraction and an elevation of cyclic guanosine 3,5-monophosphate (cyclic GMP) in rat aorta.',0 'At 1 month of follow-up 54% group B1 and 52% group B2 patients had recovered.',0 'Epidemiology of hepatitis C among veterans with alcoholic liver disease. The VA Cooperative Study Group 275.',0 'Digestive system.',0 '[Quantitative characteristics of the endocrine cells of the duodenal glands of Carnivora].',0 '[Electrophoretic analysis of the exoproducts of bacteria in the genus Pseudomonas].',0 'Of the patients, 65% had mandibular fractures, 35% had midface fractures and 5% had fractures in both the middle and lower thirds of the face.',0 'Compounds 1 and 2 showed strong activity against Cryptococcus neoformans, compounds 3 and 4 showed strong activity against Botrytis cinerea, and compounds 1, 3, and 4 showed significant activity against Phytophthora infestants (2 was not tested).',0 'Ultrastructural features of the transformation of the pseudostratified columnar ciliated epithelium to the stratified squamous epithelium in the human respiratory passages.',0 'In the present study, we have shown that the addition of culture supernatants from HIV-infected SupT1 cells (T4) but not from noninfected cells markedly increased the production of TNF-alpha by U937 promonocytic cells after stimulation with phorbol 12-myristate 13-acetate (PMA).',0 'By definition, rebel post-phlebitic ulcers are very difficult to cure.',0 'These structural changes in N. accumbens and S. nigra in rats with a genetic predisposition to cataleptic reaction reflect, probably, a pathological process in the central nervous system whose manifestation is susceptibility to catalepsy.',0 'The overall results did not show any differences between the two groups in recovery time or quality of awakening.',0 'Bioavailability assessment of a liquid prednisone preparation.',0 'Alveolar bone loss and capillaropathy.',0 'Women who have once suffered a deep vein thrombosis have an increased risk of recurrence with or without the possibility of pulmonary embolism during future pregnancies.',0 '[Sects and their influence on adolescents].',0 'A phosphorylcholine (PC)-binding IgG (Mab2) antibody produced by a hybridoma derived from a BALB/c mouse which had been immunized against Trichinella spiralis was found to bind to the immunizing antigen (TSC) but not to other PC-associated antigens such as pneumococcal antigen (PNC) and PC-conjugated ovalbumin (PC-OVA).',0 'In perfused lung preparations, each of the four atrial peptides produced dose-dependent pulmonary vasodilation of PGF2 alpha or hypoxia-induced pulmonary vasoconstriction.',0 '[Dieffenbachia: poisonous plant].',0 'There were five types of macroscopic groupings: single nodule, single nodule with extranodular growth (SNE), contiguous and noncontiguous multinodular, and massive growth type.',0 'Disjunct dentures. 2.',0 '[The Jizan project. Experience gained by the Danish Board of Health during the 1st year of cooperation with Saudi Arabia].',0 'The effects of high-K and low-Na solutions on the smooth muscle of the guinea-pig ureter have been examined in both normal tissues, and tissues in which the Na pump had been blocked by exposure to K-free solutions or ouabain (high-Na tissues).',0 'When extrapolated to infinite duration of extraction, the corrected absorbances yield a measure of the DNA content of the specimen.',0 'Subsequent management of children with febrile convulsions.',0 'Three patients with primary refractory disease were intensified.',0 'For HVJ antibody, no difference was demonstrated in positive rates unlike in the first survey, but the titers varied between the strains.',0 'It is suggested that these data support the concept that the basal ganglia participate in the enabling and sequencing of movements rather than in directly causing them to occur.',0 'A concurrent audit of high digoxin plasma levels.',0 'The change in T was attenuated (62 +/- 6 ms at 5 min of reperfusion, P < 0.05 with respect to stunned group).',0 'It was quite interesting to observe that in the upper lip, the buccal portion of the double lip appeared on either side with a midline constriction; in the lower lip, it was prominent in the midline without any central constriction.',0 'Reproductive performance of first parity sows.',0 'If the intrapericardial clot is localized, the classic echocardiographic signs of pericardial effusion may be absent, and a localized mass may be seen on the echocardiogram.',0 'These results further encourage possible clinical application of bispecific antibody in passive immunotherapy.',0 'Urinary abnormalities were the commonest side-effect (28,36%), the relatively infrequently described haematuria being the most frequent.',0 'A variety of approaches were utilized to inhibit DNA fragmentation.',0 'A survey of wasp sting injuries in urban Auckland from December to April in 1991/2 and 1992/3.',0 'Protein kinase C (PKC) is essential in intracellular signal transduction for various cell functions including natural killer (NK) cell activity.',0 'The two derivatives blocked Ca2+-induced contraction of the rat perfused mesenteric vascular bed at 3 X 10(-6) M, and developed dose-dependent shifts of the dose-response curve to the right in concentrations from 3 X 10(-6) to 10(-5) M. Yohimbine showed a weak Ca2+ channel-blocking effect only at a concentration of 10(-5) M. On the other hand, both derivatives at 3 X 10(-6) M did not affect the dose-response curve to noradrenaline-induced vasoconstriction.',0 'Reengineering quality for health care reform.',0 'Furthermore, in doubly infected cells, this mutant shows little or no recombination or complementation with other ts mutants previously mapped within the reiterated sequences of the S component.',0 'The studies were performed in vivo in male Sprague-Dawley rats under pentobarbital anesthesia.',0 'Analysis of spectra of extracts of bovine kidneys suggested that the renal MR-visible metabolites could include the osmolytes betaine, myo-inositol, and glycerophosphocholine.',0 'Acute treatment with aminoglutethimide during the mid-luteal phase decreased serum progesterone levels and increased luteal vitamin E and cholesterol ester levels.',0 'Striking EEG profiles from single episodes of glossolalia and transcendental meditation.',0 'Failure rates for the FER and Concise were 10.8% and 7.3%, respectively.',0 'Direct electrical stimulation of the esophageal or gastric muscle produced a ring contraction that spread readily across the gastroesophageal junction but did not produce a relaxation of the LES or a contraction of the longitudinal esophageal muscle.',0 'Phase II trial of cisplatin and etoposide in adenocarcinomas of the upper gastrointestinal tract.',0 'Yeast cultures, capable and incapable fo growth on hydrocarbons, were tested for their ability to oxidize aliphatic alcohols and acids, intermediate products of n-alkane degradation.',0 'There was also a significant decrease in PaCO2 in the almitrine group after 12 weeks.',0 'The hepatic assist devices are classified into three types: Artificial (charcoal hemoperfusion, PAN membrane dialysis or filtration); biological (baboon liver perfusion, cross dialysis between pig liver and patients systemic circulation); and hybrid (combined form of artificial and biological).',0 '[The development of glutamate-pyruvate-transaminase in the liver of newborn white rats and its modification through radiation effects during the fetal period or through corticoid injections after birth].',0 'Subcellular distribution of the different platelet proteins phosphorylated on exposure of intact platelets to ionophore A23187 or to prostaglandin E1. Possible role of a membrane phosphopolypeptide in the regulation of calcium-ion transport.',0 'MSC-uptake method of myocardial damage evaluation was more sensitive and precise than other methods tested (macroscopic evaluation according to Rona, increase of heart weight).',0 'Construction: hospitals top all industries.',0 'Lately, higher resolution transducers (5 MHz and 7.5 MHz) have been employed which have proven more effective due to their improved resolution.',0 'In contrast, cells of moderately differentiated thyroid cancers contained about two to three times less thyroglobulin mRNA.',0 'Multivessel operative coronary disease is common in patients experiencing ventricular fibrillation.',0 'In addition, thicker lenses as well as thicker tear films cause the lens to squeeze faster and to slide slower.',0 'Arthroscopy is definitely superior to arthrography in the diagnosis of, in particular, cartilage structures, of the synovia and of the retropatellar space.',0 'The level of plasma cyclic guanosine monophosphate, an intracellular second messenger of ANP and BNP, also decreased from 8.4 +/- 1.5 to 5.7 +/- 0.8 pmol/mL (P < 0.05).',0 '[Influence of the inhalation of hypercapnic gaseous mixtures on the evolution of acid-base equilibrium during deep hypothermia in dogs].',0 'Of the 2 regions on 17p, one involves tp53 while the second is located more distally toward the telomere.',0 'As control blood was taken from guinea pigs during nembutal narcosis or after narcotizing them by blows on the neck.',0 '20 criteria accepted by consensus were evaluated in all be clinical records of the diabetic population.',0 'The other 22 asthmatics were responders, but nine of them showed a rise of the iso flow volume.',0 'Hypertrophic cardiomyopathy: a new morphological framework in the light of two-dimensional echocardiography.',0 'Asbestos and metals as carcinogens.',0 'There was no serious drug toxicity.',0 'Histology and prognosis in malignant melanoma.',0 'To determine why black distance runners currently out-perform white distance runners in South Africa, we measured maximum oxygen consumption (VO2max), maximum workload during a VO2max test (Lmax), ventilation threshold (VThr), running economy, inspiratory ventilation (VI), tidal volume (VT), breathing frequency (f) and respiratory exchange ratio (RER) in sub-elite black and white runners matched for best standard 42.2 km marathon times.',0 'All the analogues except NECA, in a concentration-dependent manner, inhibited electrically induced contractions.',0 'Suggested benefits of primary fascial closure include earlier return of gastrointestinal function, decreased hospital stay, less sepsis, less risk of postoperative intestinal obstruction and fistulae, and lower mortality.',0 'Thirty-four percent had normal hearing, 28% had unilateral loss, and 38% had bilateral loss.',0 'We describe a patient with recurrent bruising diagnosed in the ED who responded with classic inflammation to autologous injection of red blood cells.',0 'Work hardening guidelines (position paper). American Occupational Therapy Association.',0 'Glutathione thiol esterases of human red blood cells. Fractionation by gel electrophoresis and isoelectric focusing.',0 'Plasma histidine was not affected by either arginine or lysine.',0 'Sections were viewed unstained.',0 'Nursing: an intellectual activity.',0 'Loss of CYP2E1 and CYP1A2 activity as a function of acetaminophen dose: relation to toxicity.',0 'Some epitopes were much more uniformly expressed than others.',0 'OBJECTIVE : To investigate whether the antiprogestin RU486 acts primarily on the hypothalamus to delay the midcycle gonadotropin surge and thus gain insight into the site(s) of action of P in the control of ovulation.',0 'Concentration-response curves were obtained for the two vasoconstrictors from rings with intact endothelium and from rings denuded of endothelium.',0 'The postnatal maturation of the medial preoptic area (MPOA) of male and female rats was studied by means of light and electron microscopy.',0 'Protein kinase C stimulating phorbol esters are able to mimick partially the insulin effect on glucose transport.',0 'It is recommended that the spleen should only be removed when essential.',0 '[Problems of lymphangiology in oral medicine and orthodontics].',0 'Capillary blood flow was measured on day 8 by measurement of radioactivity after injection of 15-microns radiolabeled microspheres.',0 'Transcobalamin II--cobalamin binding sites are present on rabbit germ cells.',0 'Colon mucosal membranes were prepared and examined for lipid composition and protein pattern.',0 'There was no significant difference between the groups in altering mean anxiety measurements or improving consistency of action as judged by the number of patients having reduced anxiety measurements.',0 'When furosemide was administered in combination with fludrocortisone (4 subjects), an amelioration of metabolic acidosis occurred that was greater than that observed in the group treated with furosemide alone.',0 'Our model can predict the salience of texture boundaries in any arbitrary gray-scale image.',0 'Insulin production is stimulated by high carbohydrate diets.',0 'The effects of father presence and absence upon maternal attitudes.',0 'The resonance Raman excitation profiles of a number of charge transfer transitions in electron donor/acceptor complexes with tetracyanoethylene as acceptor in solution at room temperature are reported and compared with absorption and fluorescence spectra of these complexes.',0 'Incubation of thermosensitive dna mutants of Bacillus subtilis at the nonpermissive temperature results, at the cellular level, in the appearance of swellings.',0 'Experimental compound OR-K-242-HCl an anilide derivative slows conduction velocity of the heart in the conscious beagle dog.',0 'Adenovirus infections.',0 '[An empirical study on the psychological significiance of a hospital stay for children].',0 '[Anatomy and physiology of the fallopian tubes].',0 'Administration of bromocriptine 30 min beforehand to nonsuckled rats and then suckling them for 10 min blocked the suckling-induced rise in the polymerized tubulin levels.',0 'We are in the process of isolating the genes for the alpha and gamma chains by a similar approach.',0 'Quantification of a T6-lymphocyte antigen in peripheral blood mononuclear cells of sheep was used to select 15 from 48 one year old Merino ewes not previously exposed to Dermatophilus congolensis infection.',0 '[Basic directions in the economic and social development of the USSR in the years 1981-1985 and in the period up to 1990 and the tasks of industrial hygiene].',0 '[Deferred manipulation in supracondylar humeral fractures in the child].',0 'No local or regional occurrence was observed in any patient at 6 months, or at 1, 3, 6, 11.5 and 12 years following treatment.',0 'Effects of a behaviorally active LHRH fragment and septal area stimulation on the activity of mediobasal hypothalamic neurons.',0 'A small angioleiomyoma consisting of proliferating smooth muscle cells and vessels caused macrohematuria in a 52-year-old female patient.',0 'Increased rate of calcium withdrawal from erythrocytes of patients with essential hypertension and spontaneously-hypertensive rats under the effect of Ca-ionophore and moderate Ca2+ concentrations was due to an insufficiency of the cells Ca-pump rather than disorders in the properties of K+-channels.',0 'METHODS : Direct care staff from two units for adolescents and one unit for children were trained to implement the model, which guides staff in planned and spontaneous interactions with patients.',0 'With our advancing medical knowledge and technology, the concept of chronically ill children has taken on an added dimension: technology-assisted living.',0 'In this article, the data obtained by Lee and Leblond (1985) were subjected to a mathematical analysis to obtain additional information about the rate of loss of cells.',0 'In contrast, the ribonuclease and phosphomonoesterase activities increased significantly only 4 to 5 h after infection, i.e. as late as 1 h prior to lysis.',0 'Similarly, baseline and K(+)-induced releases of LHRH-I from perifused mediobasal hypothalami from fully fed cockerels were higher than those from the hypothalami from fasting cockerels.',0 'These include differences in outcome associated with different theoretical orientations, differences between marital and family therapies versus individual therapies, the clinical significance of therapy outcome, differences between marital versus family therapies in both outcomes and problems treated, and the effects of various substantive and methodological moderators of therapy outcome.',0 'These results indicate that the human bone marrow is a selective reservoir for EBV-inducible autoantibody precursor B lymphocytes, and that the size of the reservoir increases with age.',0 'Histochemical characterization of the muscle fiber types of the Teleost (Esox lucius L.).',0 'Most abnormal findings were related to ocular dysmetria, disorganized pursuit and square waves.',0 'Mucocele.',0 'This recombinant DNA can be transformed directly into bacteria without a further ligase-dependent reaction.',0 'The response curves of the long and short type collimators to 57Co in water showed that the points at 10% of maximum counts were 4 cm and 3 cm in depth along the center axis.',0 'Although it is not suggested that MRT should replace ultrasound for the examination of pregnancy, it appears that it will be a useful technique for studying fetal growth and placental function.',0 'The value of routine preoperative pyelography in all patients with abdominal aortic aneurysm is emphasized.',0 '[Significance of retraction phenomenon for the early diagnosis of breast carcinoma].',0 'Pyrimidine metabolism in microplasmodia of Physarum polycephalum.',0 'Clearly, B. pertussis has evolved very elaborate mechanisms to maintain itself in the human host.',0 'Within 24 hours of treatment, a mean reduction of 55% of the fistula output was observed.',0 'Quality objectives were accomplished in the inter-series inaccuracy study for red cell count, white cell count, MCV, granulocytes and lymphocytes.',0 'Hyperthyroid mitochondria show an increased Km and Vmax in the high affinity phase of cytochrome oxidase kinetics.',0 'Anatomical laparoscopic hernia repair of direct or indirect inguinal hernias using the transversalis fascia and iliopubic tract.',0 'Interferon-induced transcriptional and post-transcriptional modulation of factor H and C4 binding-protein synthesis in human monocytes.',0 'Mothers reported more positive states in activities away from home, including during work at a job.',0 '[Globulomaxillary cyst. Presentation of a case].',0 'Mechanisms of killing of measles virus-infected cells by human lymphocytes: interferon associated and unassociated cell-mediated cytotoxicity.',0 'A case of metacarpophalangeal osteoarthrosis associated with synovial apatite deposits is reported.',0 'However, subjects did not differentially attribute the confederates task performance as a function of her weight or her perceived responsibility for it.',0 'Distant metastases occurred in 5/92 (5%) patients in the RS group and 13/121 (11%) patients in the RT group, but the difference was not significant (p less than 0.1).',0 '[Affinity chromatography of vegetable carbonic anhydrase].',0 'Synthesis and biological activities of analogues of angiotensins II and III containing O-methyltyrosine and D-tryptophan.',0 'Equine motor neuron disease (EMND) is a newly recognized neurodegenerative disorder of bulbospinal motor neurons in the horse.',0 'To investigate the afferent projections to the flocculus in a nonhuman primate, we injected horseradish peroxidase into one flocculus of six rhesus macaques (Macaca mulatta) and processed their brains according to the tetramethylbenzidine protocol to reveal retrogradely labeled neurons.',0 'Congenital adrenal hyperplasia was excluded on the basis of normal 17 alpha-hydroxy-progesterone plasma levels evaluated before the onset of steroid replacement therapy.',0 'Some problems of biliary tract surgery.',0 '86, 712-722] to label proteins endocytosed when water permeability declines after ADH is withdrawn to test whether the membrane proteins labeled in ADH-treated bladders behaved like particle aggregates.',0 'Our data show that BiP and N-linked glycosylation are directly involved in the processing of secreted proteins.',0 'In all, 40 units with EOM responses were examined and 25 of the 27 tested (93%) also had visual responses.',0 'Furthermore, exposure to fentanyl increased ANP immunoreactivity in the culture media while simultaneous incubation with naloxone blocked the effect of fentanyl on ANP secretion.',0 'A lingual vitamin C test: II. Daily constancy.',0 'PMN in colostrum do not appear to be beneficial to the breast-fed infant due to deficiencies in function.',0 'The deduced amino acid sequence departs from the rat sequence at 21 positions, 20 of which are in the amino-terminal trans-activation domain.',0 'Plasma and brain morphine levels were quantitatively related to the morphine concentration in drug-admixed food.',0 'Hypertropia following trauma to the trochlea is rare.',0 'Thus, while permitting generalized perfusion of tissues by clobetasol propionate, intralymphatic infusion maximizes its initial concentration and duration of activity within specific node groups and, therefore, may be useful in certain patients with primary lymphedema where lymph nodes affected by fibrosis constitute a major site of obstruction.',0 'The use of the membrane microfiltration technique in investigation of the antibiotic absorption by the macrophages provided description of the time course of the drug interaction with the cells at its early stages.',0 'The patient was readmitted because of brain metastasis 10 months later, and died 11 months postoperatively.',0 'Well-defined zones of weaker territorial staining for link protein stained strongest for chondroitin sulfate.',0 'The kinetochore in the blocked cells is a disc measuring 300-350 nm in diameter and 30-35 nm in thickness.',0 '[A case of achalasia evaluated with esophageal scintigraphy in terms of efficacy with endoscopic pneumatic dilatation].',0 'Each woman was given instructions on breastfeeding techniques to be used after delivery.',0 'One group consisted of 65 individuals treated in the hospital for pneumonia 8 weeks before vaccination (mean age, 67 years), and another group consisted of 27 individuals who had not recently been treated for pneumonia (mean age, 67 years).',0 'CSF cytology and neurologic examinations were performed biweekly.',0 'Our data indicate that the shape of IFN-alpha A molecule may be approximated by the rigid ellipsoid of revolution with the axis ratio = 4:1.',0 'We quantified the adhesive specificity of endodermal and ectodermal epithelial cells from Hydra, which are known to sort out within hours after being dissociated and then randomly reaggregate.',0 'This space varies in size but is usually tiny.',0 'Three cases of thoracic renal ectopia are described.',0 'These results suggest that factors other than the number of hippocampal BTX binding sites affect nicotine-induced seizure sensitivity, at least following chronic nicotine treatment.',0 'Evaluation of the patient with temporomandibular joint dysfunction.',0 'Regardless of solvent configuration, permeability coefficients for ara-A at 90 and 100% DMSO strengths were exaggeratedly large, consistent with severe impairment of the stratum corneum.',0 'By 1988, 71% of the 206 million married Chinese women of reproductive age were using a modern method of contraception.',0 'The cardiovascular effects of cocaine.',0 'Eleven infants were normal throughout the first year.',0 'Pill use also rose among unmarried women (from 43 to 48 percent), but there was no change in the level of sterilization.',0 'In patients who are medically inoperable an endoscopically inserted tracheal endoprosthesis may provide longstanding airway patency, as reported here.',0 'Effect of sodium nitroprusside during the payback period of cardiopulmonary bypass on the incidence of postoperative arrhythmias.',0 'The arteritis was characterized by granulomatous lesion with exclusively multinucleated giant cells.',0 'In the other regions of the brain and spinal cord of U-50,488H-abstinent rats, the Bmax and Kd values of [3H]DPAT were unaffected.',0 'With increasing bending energy, the mixtures showed increasing susceptibility to phospholipase A2, facilitated lipid transfer rate by phospholipid exchange proteins, permeability to carboxyfluorescein, incorporation of human erythrocyte proteins, and calcium transport by Ca-ATPase from sarcoplasmic reticulum in reconstituted vesicles.',0 'Maximum infusion rates and CVP accuracy during high-flow delivery through multilumen catheters.',0 'The third deuterium quadrupole splitting arises from the deuterium at position 9 of both chains.',0 'The use of this new technique, which incorporates the method of direct hemoperfusion, is suggested for future clinical studies.',0 'In its early stage of development, it provides some of the most important features of the conceptual final artificial heart.',0 'Clinical assessment of a new antiarrhythmic drug, allapinin, was carried out in 42 patients with chronic ventricular extrasystoles.',0 'Leucocytosis greater than 10,000 was found in 82.5%, some alteration of UE in 45%, and abnormal radiography in 56.5%.',0 'Visuomotor restriction of one eye in kittens reared with alternate monocular deprivation.',0 'Photography in the dental practice (I).',0 'Such centers are needed in nonacademic surroundings as well.',0 'Two cases with torsion were mainly cystic with thickening and hemorrhage of the tube.',0 'James Scott: next professor of medicine at the Hammersmith. Interview by Richard Smith.',0 'We found both forms of windup to be mediated by a depolarizing potential produced by increasing activation of postsynaptic L-type Ca2+ channels.',0 'Before challenge the patients peripheral blood mononuclear cells demonstrated a blastogenic response to the antigen.',0 'Diiodotyrosine and serotonin enhance the growth of Tetrahymena.',0 'However, local treatments reduced the frequency of renal lymph node metastasis, indicating that concurrent metastases in different sites may exhibit differential heat sensitivities.',0 'Surgery was performed in 9 patients, and 2 additional glands were confirmed by fine-needle aspiration and venous sampling.',0 'Behavioral and biochemical characteristics of rats genetically selected for high and low activity and defecation rates [proceedings].',0 'This should be considered when the workload of a specialist urological department is organised.',0 'Indications for laparoscopy in children.',0 'The results in this series failed to surpass the results obtained by others for conservative treatment alone.',0 'In a first study, nine untreated unipolar depressed patients were given the SSRI paroxetine (20 mg/day) together with pindolol (2.5 mg thrice daily).',0 '90,4% of the survivors were clinically improved: the functional result was better when the valve replacement was not a reoperation (p less than 0,02), when the patient was not in functional Class IV (p less than 0,01), in permanent excessively dilated (p less than 0,01) and in patients without severe tricuspid regurgitation (p less than 0,01).',0 '[Clinical manifestations of pertussis in children following specific immunization].',0 'Cellular localization of type II Ca2+/calmodulin-dependent protein kinase in the rat basal ganglia and intrastriatal grafts derived from fetal striatal primordia, in comparison with that of Ca2+/calmodulin-regulated protein phosphatase, calcineurin.',0 'Astrocytic elements were also present.',0 'However, the sensitivity of PSA was 73% when the cut off value was 6ng/ml.',0 'Changes in working capacity and electrical activity of muscles during the development and compensation of fatigue due to strenuous muscular activity.',0 'The hepatic histopathology in a biopsy specimen from a 5-year-old boy eight weeks after mushrooms were eaten showed bands of fibrosis and islands of hepatocytes suggestive of early cirrhosis.',0 'The partially purified protein contains bound tetrahydropteroylpentaglutamate.',0 '[Transcranial duplex sonography through intact bone: a new diagnostic procedure].',0 'Recently, renin and angiotensinogen have been identified in human ovarian follicular fluid.',0 'Melanoidins and carbohydrates in roasted barley.',0 'SOD and catalase had only a partial inhibitory effect when added after sonication (49% and 63%, respectively).',0 'To better understand the mechanisms involved, we used compartmental models derived from reconstructed neurons to simulate the effects of isolation.',0 'In this report, four children, ages 4, 5, 6, and 10 years, with adenoviral meningoencephalitis are described.',0 'Adrenal tumors are being detected more frequently in consequence of the wider application of increasingly sensitive radiological investigation techniques.',0 'E test strips (AB Biodisk, Culver City, Calif.) tested on 2% NaCl-supplemented Mueller-Hinton agar and Alamar panels (Alamar, Sacramento, Calif.) correctly characterized 127 of 127 methicillin-resistant Staphylococcus aureus isolates and 100 of 100 methicillin-susceptible S. aureus isolates.',0 'The inflamed colonic mucosa from Crohns disease patients showed similar isoelectric focusing protein patterns.',0 'Diffraction recorded from highly oriented DPPG specimens in the subgel phase extends to 2-A resolution.',0 'Two limitations, one of them being succinate limitation, were established in the present study.',0 'The thyroid primordium was temporarily everted and projected into the pharynx.',0 'The patient recovered completely after splenunculectomy.',0 'Review of a hospital experience of breast abscesses.',0 'Utilizing this method, a novel reticulocyte CD44 transcript was isolated.',0 'Comparison of the nucleotide sequences of such conserved areas defined consensus sequences that were used for the synthesis of deoxynucleotide primers.',0 '[Function scintigraphy: a uniform method for quantifying organ metabolism and function].',0 'Revised legislation.',0 'A small diphasic wave shortly preceding the monosynaptic EPSPs was interpreted as a presynaptic spike.',0 'The Resistance Index showed a good correlation with placental vascular lesions, characterized by a distinct reduction in terminal villi and muscular wall arterioles.',0 'These results suggest that O2- production by PMN could be inhibited, depending on the cumulative dose of corticosteroids in steroid-treated patients.',0 '[Rare malignant laryngeal tumors].',0 'The sialic acids. IX. Isolation of cytidine 5-monophospho-N-acetylneuraminic acid from Escherichia coli K-235.',0 'Fifty-seven percent of the patients helped by surgery had symptoms for less than 1 year, whereas only 30% of patients with symptoms for more than 1 year had symptomatic improvement.',0 'The more highly illuminated Mondrian contained a comparison patch and appeared nearer than the more dimly illuminated Mondrian, which contained the test patch.',0 'Immunological quantitation of phospholipid/Ca2+-dependent protein kinase and its fragments. Tissue levels, subcellular distribution, and ontogenetic changes in brain and heart.',0 '[Changes in phosphocreatine and adenine nucleotides in the brain of mice chronically poisoned with methamphetamine. Neurochemical studies of behavioral abnormality].',0 'O2- -induced LCL dose dependently.',0 'Within the skin IgG and IgM were consistently found in the interstitial tissue throughout the dermis and were commonly present in the dermal blood vessels and hair papillae.',0 'Fetal weight was affected to a greater extent than the cerebellar diameter, leading to discordance between the two parameters.',0 'The data are tabulated along with similar data from Taiwan to provide a basis of comparison.',0 'Adaptation was inhibited by cycloheximide (3 mug/ml) and by actinomycin D (0.05 mug/ml).',0 'In gonadotrophs, GnRH triggers rhythmic hyperpolarizations due also to a K+ conductance increase.',0 'Role of histidine residues in the adenosine A2a receptor ligand binding site.',0 'Although the fate of the minor 7S component of the rete testis fluid in its epididymal transit is presently unknown, similarities between the enzyme in cauda epididymidis and seminal plasma are strong enough to support the hypothesis that epididymis contributes primarily to the acid alpha-glucosidase content of ram seminal plasma.',0 'Mechanisms of suppression in Drosophila. IV. Specificity and properties of tyrosyl-tRNA synthetase.',0 'Scarce granules of variable size and density were seen in atrial myocytes, and some Purkinje-like fibers were observed.',0 'Limited involvement of interleukin-6 in the pathogenesis of lethal septic shock as revealed by the effect of monoclonal antibodies against interleukin-6 or its receptor in various murine models.',0 'In the rat, the hippocampus and dentate gyrus contained fewer immunoreactive fibers.',0 'At least 104 nucleotides are transposed from the 5 terminus of the avian sarcoma virus genome to the 5 termini of smaller viral mRNAs.',0 'The Wiener, or minimum mean square error filter sharpens the image while also reducing noise.',0 'A comparison of the properties of the mutant and wild-type proteins identifies a significant role for the normal N-terminal acetylation of the zeta-chain with regard to the alkaline Bohr effect and the sensitivity of the oxygen affinity of the protein towards chloride ions.',0 'Thus, this procedure also did not alter orbital volume.',0 'Polypeptides of nonpolyribosomal messenger ribonucleoprotein complexes of sea urchin eggs.',0 'The data demonstrate a degree of satisfaction with, and acceptance of, health delivery service in this specific urban area.',0 'In vivo myocardial reactivity to norepinephrine based on assessments of left intraventricular developed pressure, positive and negative dP/dt and delta dP/dt was depressed significantly in untreated diabetic rats.',0 '[Erythrocyte glucosephosphate dehydrogenase deficiency as a factor in a drug-induced hemolytic crisis in a patient of Asiatic origin].',0 'Eleven patients who were HBsAg positive before transplantation developed signs of hepatitis.',0 '[Treatment of phobias by behavior therapy].',0 'The effect of superoxide dismutase and catalase on myocardial reperfusion injury in the isolated rat heart.',0 'Both the techniques of preiodination of PMPITC followed by conjugation and radioiodination of PMPITC-conjugated AHON were evaluated; the latter was found to be more convenient.',0 'The exact mechanism of target cell recognition by LAK cells remains unknown.',0 'Intravenous (IV) digital subtraction angiography (DSA) was performed in 12 patients with suspected aortic aneurysm/dissection.',0 'Platelet-associated C3 (PA-C3) was measured with a quantitative immunofluorescence assay.',0 'The present study deals with the appropriate statistical approach to the histomorphometric technique carried out on bone tissue with the Merz and Schenk integrating eyepiece.',0 '"Biometabolische Modi" and heterochrony in the phylembryogenesis of the nasal apparatus of birds.',0 'The results suggest that dc shocks delivered at instants of higher values of integrated AVFV over the various window sizes are associated with successful defibrillation.',0 '25): C674-C682, 1989].',0 'The development of plaques could not be prevented by benzarone, however, the growth of the atheromatous plaque was inhibited and the incorporation of lipids into the plaques was less pronounced than in those animals which received a diet with cholesterol but without benzarone.',0 'Thyroid stable iodine measurement in patients with hyperthyroidism.',0 'Blood pressure, cholesterol, triglyceride, and LDL-cholesterol concentrations were elevated and HDL-cholesterol levels were lower among those with abnormal rather than normal glucose tolerance.',0 'Serologic evidence of naturally occurring Venezuelan equine encephalomyelitis virus infection in a dog.',0 'At the dermal subcutaneous junction, there were prominent subendothelial collections of nevus cells in large veins.',0 'SDS-PAGE analysis showed remarkable differences between the VFCC and the hydatid antigens composition and some differences among these latters probably due to manufacturing procedures.',0 'Heavy inocula (3.7 x 10(6) cells per cm(3)) maintained the cells in stationary phase, and under these conditions no induction of hemoglobin synthesis occured.',0 'Idiopathic cephalic pain, together with deafferentation or opioid-abstinence pain, seems to be due to a dysafferentation which, through different channels, follows an analogous mechanism.',0 'In this paper, an attempt is made to define common goals of doctors and patients and to describe the information status of both the patient and the doctor concerning the disease.',0 'A biometrical examination of the organs showed a statistically significant decrease in heart weight in the cyadox-treated group, increase in liver and heart weight and intestine shortening in the virginiamycin-treated group, in comparison with the control group.',0 'The MCQ group tries to ensure that the knowledge tested is that appropriate to a well trained and well informed young general practitioner.',0 'The combination of ulceration and multiple metastatic nodes had a profound adverse effect on survival rates.',0 'During the past 10 yr an increasing number of cases of hepatic adenomas and related lesions has been reported in women using oral contraceptives.',0 'Domiciliary ventilation has been used for 40 years, and is an effective treatment for chronic hypoventilation and thoracic deformity.',0 'The nutritionist in food aid.',0 '[The participation of neuropeptide Y and the catecholaminergic systems of the brain in feeding behavior].',0 'Transepithelial potential measurements in the isolated, perfused head of a marine teleost.',0 'The method is simple, cheap, easy to use in field practice, in particular in junior patients.',0 '[Nutrient medium for simultaneous detection of lecithovitellase activity and pigment production in staphylococci].',0 'Here, supported bilayers are applied to study the lateral diffusion and lateral distribution of membrane-bound monoclonal antibodies.',0 'The ability of the AMLR supernatants to mediate the cytotoxic T-cell response to altered self was also pH 2 sensitive.',0 'A particular need exists for a theory that can be used for measurements of tumors in which many cells are not actively cycling and only a single time point can be obtained.',0 'Disruption of conditioned taste aversion by the combined effects of LiCl and ECS.',0 'Organising cancer research.',0 'Exposure during mid-gestation resulted in early and transient hyperactivity, but no learning or memory deficits at 2 months of age were observed.',0 'Acceptance remarks on receiving the William Wood Gerhard Medal of the Philadelphia Pathological Society.',0 'A case study presents diagnostic and therapeutic problems familiar to family physicians.',0 'The chemotherapeutic response of a series of patients with bronchial carcinoma has been compared with the response of their xenografts established in immune-suppressed mice.',0 'Porphyromonas gingivalis is capable of in vitro growth when iron sources are either complexed to hemin or host iron transport proteins, or exist in an inorganic form.',0 'The distribution of both tyrosine hydroxylase (TH) antigen and messenger RNA was investigated in the ventral mesencephalon from human brain using a 35S-labeled human TH cDNA probe and a polyclonal TH antibody.',0 'Speech discrimination was 78% preoperatively and 69% postoperatively.',0 'Calcium had an antagonistic effect on cadmium toxicity, and at a calcium concentration of 200 mg 1(-1) experimental animals failed to reach 50% mortality after a period of 120 hr.',0 'Sleep variables and measures of gas exchange were determined on two consecutive nights; on the first night the subjects breathed supplemental oxygen, and on the second they breathed room air.',0 'The relationship of the measurements to the age of the fetuses are presented on the basis of a linear regression analysis.',0 'The nurse recorded a single "end-hour" value of ICP from the bedside monitor while the computer averaged 720 data samples of ICP during the hour.',0 'Detection of feline T-lymphotropic lentivirus (FTLV) infection in Japanese domestic cats.',0 'In addition, 31% of the MAN dose was exhaled as organic volatiles in 24 h compared to less than 2% of an equivalent AN dose.',0 'Autoregulation and regional blood flow of the dog during hemorrhagic shock.',0 'This is assumed to be caused by binding of the agents to the viral glycoproteins.',0 'The levels of plasma free carnitine and ketone bodies have been found to fluctuate inversely in fasting individuals without muscle disease.',0 'Thus, 2-dimensional echocardiography can provide both quantitative and qualitative information about the caval and pulmonary venous pathways after the Senning procedure.',0 'We used multiple dipole modeling to study the number, three-dimensional intracerebral location, time activity, and functional relationship of the neuronal sources underlying the epileptic spike complexes.',0 'One milliliter of each aliquot was diluted to a zidovudine concentration of approximately 40 micrograms/mL and assayed in duplicate by a stability-indicating high-performance liquid chromatographic method.',0 'alpha-Bungarotoxin is also a potent antagonist at the cockroach central nicotinic receptor, and binds (Kd = 4.3 nM) to a nicotinic site in cockroach nervous tissue.',0 'There is evidence that individual nutrients or nutrient derivatives may either provoke or prevent metabolic and physiologic perturbations of the vascular endothelium.',0 'Referential style at thirteen months: why age-defined cross-sectional measures are inappropriate for the study of strategy differences in early language development.',0 'Based on the study of genomic structures of these human glycophorins and the genetic and immunological study of primate glycophorins, we hypothesize that chimpanzee and gorilla glycophorin B could possess a longer extracellular region and carry a stronger N blood group antigenicity compared with that of the human.',0 'The mean age of exposed workers was 34.2 years, mean duration of past exposure 5.1 years.',0 'Effects of liposome-encapsulated dichloromethylene diphosphonate on macrophage function and endotoxin-induced mortality.',0 'Extensive signal attenuation was observed when gradients were parallel to white matter fibers.',0 'Benzo[a]pyrene transformed 3T3 (BP3T3) cells have a 100--200 times lower Ca++-requirement than 3T3 cells but arrest in G1 at low Ca++ levels.',0 'Four were goal attainment scaling programs that have proved durable over time in their host organizations versus six other programs in which goal attainment scaling did not survive despite some initial success.',0 'Enhanced collagenase activity in diabetic rat gingiva: in vitro and in vivo evidence.',0 'The binding of radiolabeled dihydropyridine, which correlates with the total number of calcium channels in the membrane, was increased by 14 days gestation, in comparison to that in nonpregnant controls.',0 'The pharmacokinetics of didanosine (2,3-dideoxyinosine) after intravenous and oral administration were evaluated in an open, escalating-dose phase I study in patients with acquired immunodeficiency syndrome (AIDS) or severe AIDS-related complex.',0 '[On polysaccharides from Godetia whitneyi gray inhibiting the growth of transplantable tumors].',0 'In addition, the number of labelled nuclei increased significantly in the yet un-enlarged left ventricle.',0 'Synthetic sentence identification as a function of the age of the listener.',0 'However, during a 42.2-km marathon run on a treadmill, the black athletes ran at the higher percentage VO2max (76%, SD 7.9% vs 68%, SD 5.3%), RER (0.96, SD 0.07 vs 0.91, SD 0.04) and f (56 breaths min-1, SD 11 vs 47 breaths min-1, SD 10), and at lower VT (78 ml kg-2/3 breath-1, SD 15 vs 85 ml kg-2/3 breath-1, SD 19).',0 'Simultaneous competitive enzyme immunoassay for human chorionic gonadotropin.',0 'Antibody levels were not restored after the first untreated recurrence.',0 'Pulmonary function tests in bronchial asthma (study during symptom free period before and after a bronchodilator).',0 'Phytochemical investigations of some Tylophora species found in India.',0 'The procedure with the least morbidity and the fewest undesirable side effects is proximal gastric vagotomy.',0 'The major pitfall of these procedures is a too perfectly preserved sphincter which remains spastic and still produces obstruction.',0 '[Day-hospital in England].',0 'The whole tone response showed two distinctive time patterns that could be fit to either an adaptation equation or to the two-time-constant recovery equation, depending on the relative amplitude of the masker and the length of the silent interval between masker offset and probe onset.',0 'Conversely, nPAECs expressing CD59 were not protected from lysis by rabbit or dog complement, indicating that recombinant CD59 retained its species-restricted inhibitory activity.',0 'Teniposide liposomes were prepared by dissolving egg phosphatidylcholine and dioleoyl phosphatidic acid (19:1 molar ratio) in methylene chloride together with teniposide.',0 'The intra- and interobserver reproducibility of this method of measuring AWUV were examined.',0 'Thus, with respect to current speculation as to whether visual imagery is a necessary component of mental rotation, the present findings suggest that it is not.',0 'Sickle cell trait, maternal age and pregnancy outcome in primiparous women.',0 'The melanocytes are acutely sensitive to a single pulse of UV and express neural differentiation.',0 'Suspected staphylococcal food poisoning from ham and shrimp obtained from maltreated cans.',0 'Problems at work can interfere with the socio-structural system.',0 'Electrically detachable coils represent a significant advance in the arsenal for endovascular treatment, although this device will not replace open surgery.',0 'The pathogenesis of these perimacular folds found in adults sustaining direct head trauma is probably different from that previously described for folds seen in infant eyes with shaken baby syndrome.',0 'The specificity and neutralizing activity of antibodies against the major herpes simplex virus type 1 (HSV-1) glycoproteins were tested in serum samples of patients with a history of HSV-1 infection.',0 'In the past, several indices have been proposed to evaluate the threat of vectors to the community.',0 'The method described here offers one approach to identifying combinations worthy of evaluation in prospective comparative clinical trials.',0 'The work capacity of patients on maintenance hemodialysis is impaired even at normal inspiratory oxygen pressure.',0 'Isolation of mycoplasmas in leukemia and other diseases.',0 'Parts of the SS gene and the complete 5S gene were sequenced.',0 'Prazosin (9.5 nmol, icv), a selective alpha 1-adrenoceptor antagonist, attenuated the stimulatory effect of 5 mcg NPY on food intake.',0 'It can be concluded that there is no significant difference in the pharmacokinetics of pirenzepine between gastric and duodenal ulcer patients.',0 'Neutron scatter and diffraction techniques have made substantial contributions to our understanding of the structure of the nucleosome, the structure of the 10-nm filament, the "10-nm----30-nm" filament transition, and the structure of the "34-nm" supercoil or solenoid of nucleosomes.',0 'In the North Paddington Primary School Study 350 children were identified at five and studied over a five-year period.',0 'Two cases of Cruveilhier-Baumgarten syndrome not clinically evident and without esophageal varices in patients with liver cirrhosis and portal hypertension are presented.',0 'Immunoreactivity for annexin VI in vascular structures was localised to the nuclei of endothelial and smooth muscle cells.',0 'All the cases have been resolve positively.',0 'The unconsciousness time was similar in the three groups, whereas awaking time and time of response and orientation were longer after thiopental and etomidate than after propofol.',0 '[Isolated dissection of the renal artery treated by conservative surgery in 3 patients].',0 'Reserpine did not decrease the output of 5-HT and 5-HIAA 24 h later and p-chloroamphetamine increased 5-HT in both vehicle- and reserpine-treated rats severalfold.',0 'Serum calcitonin and blood mineral interrelationships in normal children aged six to twelve years.',0 'Among the cephalosporins, the extended spectrum, third generation agents developed generally produce few side effects and appear to be less allergenic than the penicillins.',0 'Persistent high catalepsy scores across the six catalepsy rating sessions were strongly associated with the development of persistent severe VCMs.',0 'For X-ray doses from zero to approximately 120 rads, TPA raises transformation to frequencies approximately equal to those due to neutrons alone.',0 'In summary, we have demonstrated two cholinergic responses of hippocampal pyramidal cells that are mediated purely by muscarinic receptors.',0 '[Role of IgE in the study of the allergic risk of the young child (authors transl)].',0 'Granular cell tumors are uncommon benign neoplasms infrequently seen in the hand.',0 'Comparisons with other types of sequences confirm and clarify the tripartite domain structure of chorion proteins.',0 'The three Eyetone instruments tested were comparable in their accuracy and functional stability.',0 'An open clinical trial with prifinium bromide, an anticholinergic agent, was carried out in 21 patients with irritable bowel syndrome showing clear psychosomatic characteristics.',0 'We report preliminary data on aphasic patients who, in spite of their language problems, have succeeded in finding a reasonably satisfactory occupational resettlement.',0 'Continuous infusion of beta-lactam antibiotics: a rational dosing approach.',0 'Protein characterization of Babesia equi piroplasms isolated from infected horse erythrocytes.',0 'Both the nosocomial and community-acquired infections occurred randomly during the 17-week span of the epidemic.',0 'Taken together, CGRP seems to play an important role in the regulation of coronary vascular tone, while it has only a small functional role in inotropism and chronotropism in canine hearts.',0 'Chromatin fragmentation is an enzymatic process which depends on the activity of endogenous nuclease(s) and the susceptibility of chromatin to endonuclease activity.',0 'Failure strength and method of failure were recorded for these anchors as a function of time.',0 '[Significance of the alpha lipoprotein-cholesterol level in healthy subjects and patients with myocardial infarct].',0 'In the short photoperiod (8L:16D) no clearcut ML rhythm was observed.',0 'Behavioral thresholds to changes in the volume of the gut were recorded and compared in the two loops.',0 'Although the instruments are rigid, they can be passed transurethrally in both male and female patients to allow the urologist to diagnose and treat many lesions of the upper urinary tract.',0 'This finding dispels the myth that nursing service is an expensive expenditure for hospitals.',0 'Also, the binding of iodinated Ab2 to Ab1 was inhibited by rabbit antisera specific for gp37.',0 'Of those treated with repeat ORIF, nine (82%) achieved radiographic union at an average time of six months.',0 'The kinetics of CD25 expression following activation were found to be different for B- and non-B-cells.',0 'The projected 2-year event-free survival was 24% for all 40 patients and 49% for the non-Hodgkins lymphoma patients.',0 '[Socialist competition of health center feldshers].',0 'Exchange of gII(PrV) for gI(BHV-1) in recombinant 9112C2 or by phenotypic complementation of gII- PrV propagated on gI(BHV-1)-expressing cell lines resulted in penetration kinetics intermediate between those of wild-type PrV and BHV-1.',0 'Three groups of eight patients were studied: group 1 patients received a loading dose of 0.4 mg IV naloxone followed by naloxone infusion at a rate of 10 micrograms.kg-1.',0 'To test this hypothesis, we made multiple partial-thickness wounds (5 X 7 X 0.3 mm) on six domestic pigs.',0 'V(D)J recombination in ataxia telangiectasia, Blooms syndrome, and a DNA ligase I-associated immunodeficiency disorder.',0 '[Sacred cows in a hallowed health system].',0 '[Hand injuries (data from the Department of Orthopedic Trauma Surgery)].',0 'Co-trimoxazole and aminoglycosides were also active.',0 'In over 30 years of surveillance of 2873 women, 574 developed initial clinical manifestations of CHD.',0 'While altered drug handling is a major potential source of difference in responsiveness to drugs, the relative contribution of pharmacokinetics and pharmacodynamics to this difference is not clear.',0 'No changes in ACTH, cortisol or glucose plasma levels were observed after acute normal saline, either before or during captopril administration.',0 'In this paper, I attempted to illustrate the process of separation and growth in the third analysis of a Holocaust survivors daughter.',0 'The segmental and central distributions of renal nerve afferents in adults cats and kittens were studied by using retrograde and transganglionic transport of horseradish peroxidase (HRP).',0 'In additon, there was evidence of tubular obstruction.',0 'Hence, delayed healing of a fracture and formation of pseudarthroses are attributed to shear forces, insufficient retention and generally to lack of rest in the fractured area.',0 'The disappearance of favus due to T. schoenleinii may be due to improved socioeconomic conditions.',0 'Chloramphenicol, dexamethasone, and B complex vitamins were administered and the horse recovered.',0 'A new test of colour vision using computer graphics has been used to obtain quantitative estimates of colour contrast sensitivity in ophthalmologists before and after they have treated patients by argon laser retinal photocoagulation.',0 'Exposure to dimethylacetamide was measured in a plant where a prefabricated synthetic product was handled and mechanically processed.',0 'The neurophysiological course of the ejaculation into the posterior urethra, the emission, is described.',0 'The overall results were excellent or good in 35 patients (76.1%) and fair in 11 patients (23.9%).',0 'Furthermore, addition of A-1254 to the embryo culture medium was associated with a significant decrease in embryo growth at 48 h and 96 h. These results demonstrate adverse effects of A-1254 on oocytes, IVF, and embryonic development in the mouse.',0 'A cell line that encodes the ts M gene was transfected with the infectious HIV-1 DNA or was infected with HIV-1 or HIV-2.',0 'The gene encoding the 180-kDa DNA strand transfer protein beta from the yeast Saccharomyces cerevisiae was identified and sequenced.',0 'The operation is simple to perform and postoperative immobilization is minimal.',0 'The research arose from practice, and it contributes to theoretical explanation of nursing interaction, and the relationship of systems thinking to understanding of the nursing situation.',0 'Barbiturate enhancement of GABA-mediated inhibition and activation of chloride ion conductance: correlation with anticonvulsant and anesthetic actions.',0 'There was a markedly higher incidence of eclampsia during the colder months.',0 'Estrogen receptor replenishment. Evidence for receptor recycling.',0 'An immunocytochemical study of p53 and bcl-2 protein expression in Hodgkins disease.',0 'Signals that regulate transcription are highly conserved through the family barriers.',0 'We show that heterogeneity can seriously affect the treatment comparison and has to be considered during the planning stage as well as at the analysis of a clinical trial.',0 'After a single oral dose of nitrazepam 5 mg the most prominent differences between the experimental groups were in the beta-phase half-life mean 29 h in the young volunteers and 40 h in geriatric patients , and in the apparent volume of distribution during the beta-phase of 2.4 vs 4.8 1/kg.',0 'In order to provide a perspective on the state-of-the-art in aquatic toxicology relative to classical toxicology, the two fields are compared from the standpoint of the type of scientist practicing each field, the respective objectives of each, the forces which drive the activity in each field, and the major advantages and disadvantages accruing to the practitioner of aquatic toxicology as a result of the differences in objectives and driving forces.',0 'In contrast, neither the omission of calcium ions nor the addition of 0.5 microM tetrodotoxin affected dialysate 5-HT or 5-hydroxyindoleacetic acid (5-HIAA).',0 'The overall survival rates were identical.',0 'Their presence in the aspirate confirmed a cytologic diagnosis of NHL in 47 cases, helped to diagnose NHL in 31 cases in which a cytologic differential diagnosis with small cell anaplastic carcinoma could not be made with confidence and helped to change the initial cytologic diagnosis of anaplastic carcinoma to NHL in 4 cases.',0 'Very low densities of neurotensin receptors were visualized on gestational days 14 and 15.',0 'These findings are contrasted with the differential pattern of activation that is assumed to occur in vivo.',0 'This paper discusses one of the more uncommon sequelae of ureterocolic anastomosis, namely the formation of tumours at the site of anastomosis.',0 '[Vitamin C in the past and at present (authors transl)].',0 'Fluorescence polarization measurement during the progress of fluorochromasia has been used to study the response of human lymphocytes to phytohaemagglutinin (PHA) and to tumour-associated antigens, as a basis for the detection of malignant disease.',0 'In follow-up ranging from one to 30 months, cessation of major bleeding was achieved in 12 of 13 patients (93%), although 5 of 13 patients (40%) did have recurrence of minor hemoptysis.',0 'Further examination revealed that he had primary myelofibrosis with cutaneous extramedullary hematopoiesis.',0 'Finally, our results also support the hypothesis that negative selection (deletion) does not require previous positive selection because deletion was observed under conditions where positive selection had not occurred.',0 'Patterns of serum cortisol levels in ovariectomized females with and without androgen administration.',0 'The authors conclude that consideration of quality of life in making life-and-death treatment decisions may involve judgments about the value of life, and that responsible consideration requires guidelines grounded in ethical principles.',0 'The morphological features in SAM more closely resembled those seen in cases of murine spontaneous senile amyloidosis than the features seen in cases of experimentally induced amyloidosis.',0 '[On the origin of the cells covering the basal plate and bounding the intervillous space in the human delivered placenta].',0 'Concentrations of albumin in lavage fluids were measured as an index of mucosal exudation of plasma.',0 'Among the risk factors, some are specific (age > 65 years, gallstones in the common bile duct with or without jaundice, history of acute cholecystitis or of biliary surgery) and the others are non specific such as the CDC new index risk (for scoring from 0 to 3, wound infection rates are respectively 1.36, 2.01, 7.11, 11.54%).',0 'Smoking cessation counseling in adults and children: the clinicians role.',0 'Before the distribution of these packages, many meaningful projects could not be attempted, simply because the data analysis phase would have been too labor intensive.',0 'Biologic function of the Fc fragments of E myeloma protein.',0 'In bone, early events in inflammation involve the production and release of primary proinflammatory cytokines, such as interleukin-1 beta.',0 'From the 21 cases 8 revealed a good morphological response to chemotherapy (33%); 10 of the 13 non-responders were positive for P glycoprotein (77%), but only 2 of the 8 responders (25%).',0 'Copolymers of L-lactide, D,L-lactide, and epsilon-caprolactone were selected for diversity of mechanical properties and degradation rates.',0 'These sites bind calcium with an apparent binding constant (KCa) of 4 X 10(3) M-1 at 50% saturation under physiological conditions, and KCa/ KMg is about 1.6.',0 'Lymphokine and hematopoietic growth factors control the differentiation and proliferation of diverse cell types by binding to specific cell-surface receptors.',0 'PURPOSE : To present a case of a girl with bilateral retinoblastoma, who, despite of the continuing development of the disease, survived for twenty years.',0 'It was found that intact tail fibers had a sedimentation coefficient of 12 to 13S and that dissociated fibers consisted of three classes of proteins having molecular weights of 150 K +/- 10, 42 K +/- 4, and 28 K +/- 3 daltons.',0 'The excretion of hippurate in the urine unmatched by ammonium also mandates an enhanced rate of excretion of the cations, sodium and potassium.',0 'Animal rightists have attacked the dairy industry because of farm conditions, bovine somatotropin, overproduction of milk, dairy lobbies, and advertising of milk products.',0 'Specificity of the glucose effect was shown by the binding of insulin and transferrin to their respective receptors, which was unaffected by the high glucose concentration that increased asialoorosomucoid binding.',0 'Results obtained in 50 children with abdominal non-Hodgkins lymphoma after a treatment program that comprised entire abdominal irradiation and chemotherapy are presented.',0 'However, when NVB was administered intermittently at CED, it exhibited significant antitumor activity against three tumor lines.',0 'Susceptibility patterns to infection by the nine phage isolates among the V. vulnificus test strains suggest that the latter may fall into several groups.',0 'Although first-year and more experienced students have similar career goals upon entering a doctoral program, the career goals of doctoral nursing students do change over time.',0 '[Nursing care in emergencies].',0 'Anti-insulin and -glucagon were used to identify islet cells.',0 'This may be a result of cardiovascular deterioration associated with diabetes mellitus.',0 '[Change in the vitamin B12 level in the blood in certain stomach diseases].',0 'Although metabolic products from Aspergillus terreus var.',0 'Barbiturate interferences are eliminated.',0 'This functional response to A23187 could be abrogated, without any concomitant change in sperm motility or viability, by using membrane permeant thiols or catalase to suppress the reactive oxygen species-induced increase in phosphotyrosine expression.',0 'Also in vitro solubility studies were carried out using the Sartorius solubility simulator.',0 'Vitamin B-6 deficient and control rats were subjected to sham hepatectomies and used as controls.',0 'Addition of 0.1 mM forskolin further increased the cAMP accumulation in MCT incubated with AVP.',0 'Among the "white-collar" families belonging to the intervention group, the proportion of mothers who stopped smoking was 3 times higher than in the control group (not statistically significant).',0 'It would also be beneficial if Dr. Mehta could take time to train others in his technique.',0 'The results have shown that the hydrolysis of each steroid sulfate is mediated by different particulate enzymes, which demonstrate optimal activity between pH 6.0-7.0.',0 'In view of the known hypermobility syndrome of the first ray that results in insufficient weightbearing beneath the first metatarsal head, the relationship between this syndrome and hallux valgus deformity has been investigated.',0 'These data demonstrate that, while the renal nerves appear to play a modulatory role in the development of the hypertension, they are not essential for the pathogenesis to occur nor do they determine the final level of hypertension achieved following chronic infusion of angiotensin II in the rat.',0 'Seventy-six New Zealand White infant male rabbits (4-week-olds) were used.',0 'Effect of a prostacyclin analogue on the vasopressin and oxytocin secretion in vitro.',0 'In the fifth experiment, the chemotactic response of neutrophils to casein was shown to be significantly depressed by the addition of bronchial washings obtained from immunized rats (P < 0.01).',0 'Enteropathogenic strains of Yersinia enterocolitica harbor a virulence plasmid (pYVe plasmid) of 70 kilobases (kb) which specifies, at 37 degrees C, a calcium requirement for growth, autoagglutinability, resistance to the bactericidal activity of human serum, and the expression of outer membrane proteins (OMP).',0 'The concentration of acetic acid only increases slightly when the cell concentration is increased.',0 'Repeated doses of methomyl induced inhibition on the (KH) and (KATE) activities, whereas repeated treatment with cypermethrin had no effect on the activities of these enzymes.',0 'Pf 51 cases of Fallots tetralogy who underwent preoperative angiography before a palliative anastomosis and then a second angiography before complete correction, 10 had developed pulmonary atresia (infundibular in 8 cases, valvular in 2 cases).',0 'Evaluation of buffy-coat microscopy for the early diagnosis of bacteraemia.',0 'High resolution two-dimensional PAGE was used to analyse protein variation among serotype 1 poliovirus isolates.',0 'The data suggest that in addition to common sites of interactions between these proteases and C1(-)-INH, there are also points of contact that are specific for each protease.',0 'Both short-axis and apical four-chamber views were useful in the assessment of diastolic function by ABD.',0 'MAIN OUTCOME MEASURE(S) : Two hundred spermatogenic cells were counted and classified at the various steps of spermatogenesis.',0 'Some of the nutritional concerns of female athletes are highlighted in this case study of a 20-year-old woman who wants to lose 16% of her body weight to qualify for the position of coxswain on a national crew team.',0 'Fetal binucleate cells interrupted the microvillar junction and penetrated as far as the basement membrane of the uterine epithelium.',0 '[Structural changes of adenomatous gastric polyps in process of their development and malignization].',0 'An immunodominant CD8+ CTL response was HLA-A3.1 restricted and recognized a 10-amino-acid epitope (gp120/38-47) in a highly conserved region of gp120.',0 'Grass conjuvac. I. Immunogenicity in rabbits, guinea pigs and rats.',0 'The efficiency, acute and delayed toxicities of different radio-chemotherapeutic combinations were assessed on an in vivo model (Krebs II ascitic carcinoma grafted to female Swiss mice).',0 'The authors studied the demographic characteristics and history of psychiatric treatment of 214 homicide victims and 67 suicide victims.',0 'Commissural connections mediate inhibition for the computation of interaural level difference in the barn owl.',0 'Most of the snRNAs are back in the nuclei by telophase, but the intranuclear localization is hard to determine.',0 'We report a case of "naturally-occurring" (nonred blood cell stimulated) anti-K1.',0 'The half-life of this insecticide in freshwater is approximately 3 days at a pH of 10 and temperature of 36 degrees C. At lower pH conditions of 6 and at the same temperature, DFB is more persistent since half-life values of approximately 9 days have been reported.',0 'The second process is Na+-independent, is less concentrative, and may be composed of two distinct systems as suggested by pyruvate inhibition studies.',0 'Suspensions of cell wall and cytoplasmic material were injected intradermally, and the lesions appeared only at the site of cell wall injection.',0 'The 5-region of the T-KG gene responsible for conferring both of these effects was localized between nucleotides -404 to -210 upstream of the transcription start site.',0 'Since many women have used a series of different formulations, and there exists no good method of attributing progestational potencies to different combined pill formulations, it is impossible to tell whether the progestin is responsible for any heightened risk of breast cancer.',0 'No clinical benefit accrued from the use of pre-treatment scans.',0 'Among 302 randomly ascertained adults not previously known to have diabetes, both fasting and postmeal levels in subjects with impaired glucose tolerance (IGT) and newly identified type II diabetes were equal to or greater than levels in subjects with normal glucose tolerance (fasting: normal 52 pmol/L, IGT 78, new type II 87; postmeal: 317, 565, and 406, respectively).',0 '[Treatment and prevention of asymmetrical intrauterine growth retardation with huoxue huayu prescription].',0 'In several cases, abnormal impulse formation was found, but the majority of arrhythmias (75%) was caused by a circus movement of the impulse.',0 'Mice infected with the Venezuelan equine encephalomyelitis virus showed a significant decrease in the GABA content of cerebral hemispheres.',0 'Biliary surgery in patients with PDD and a dilated bile duct should include a biliary drainage procedure to prevent recurrence of pancreatobiliary disease.',0 '[Hereditary coproporphyria (authors transl)].',0 'We modified the Hybritech Tandem-E TSH High Sensitivity assay for chemiluminescent detection of bound alkaline phosphatase label by using this substrate (with 20-, 40-, and 60-min incubations).',0 'Bovine pineal antireproductive tripeptide binds to luteinizing hormone-releasing hormone: a model for peptide modulation by sequence specific peptide interactions?',0 'Mice given a protein-free diet for six days had significantly fewer CFU-E and BFU-E numbers per femur compared to mice given a diet with normal protein content.',0 'Plasma interference affected the absolute values of plasma AVP concentrations of osmotically-stimulated normal and diabetic subjects.',0 'A yeast artificial chromosome containing ADCYAP1R1 was identified in the CEPH "B" Mega-YAC library.',0 '[Progress on mechanism and countermeasure study on senility in China].',0 'Central nervous system metastases of choriocarcinoma. 23 years experience at Charing Cross Hospital.',0 '[The treatment of patients with the anococcygeal pain syndrome].',0 'Promotion of resolution of phosphorylated forms by raising the temperature or in the presence of glycogen indicates that the resistance of phosphorylase a and ab to resolution at 0 degrees C is due rather to their tetrameric state than their phosphorylation-related active conformation.',0 'Denaturation experiments performed with increasing concentrations of guanidine hydrochloride (Gdn-HCl) at neural pH indicated that the active site of the enzyme was destroyed by a structural rearrangement of the protein molecule without large change in its size and shape.',0 'It is inhibited when the redox potential is increased above -300 mV either via substrate oxidation or via direct addition of oxidizing agents.',0 'To provide an index of individual sensitivity to expoxides, we previously studied sister chromatid exchange (SCE) induction in peripheral blood lymphocytes and identified a trait involving sensitivity to chromosomal damage by monoepoxybutene and diepoxybutane (DEB), both potential carcinogenic metabolites of 1,3-butadiene.',0 'It failed to form visible plaques, although it could be handled as a prophage and sufficient phage particles be isolated to allow characterization of the insert.',0 'Hemangioblastoma of the brain stem presenting as hypertension.',0 'Serum immunoglobulins A (IgA) and M (IgM) titres were determined in 25 patients with sickle sickle cell anaemia (HbSS) in steady state and in 25 age and sex-matched normal controls.',0 'Both APV (1 microM and 100 microM) and ketamine (1 mM and 100 mM) inhibited the increase of dorsal horn neuronal firing rate induced by ischemia, but did not alter the neuronal response to noxious pinching or innocuous brushing of the receptive field.',0 'Mean age at repair was 14 years and at follow-up evaluation 33 years.',0 'Addition of antibody to TNF-alpha during the cytotoxic phase of response resulted in a reduction of about 50% in the percentage of cytotoxicity, indicating TNF-alpha as one of the lytic mediators.',0 'The subunit structure is suggested to be alpha 2 beta 2.',0 'Gastrointestinal Polyposis: Syndromes and Genetic Mechanisms.',0 'No significant ciliary ultrastructural abnormalities were seen in any tissue.',0 'It is characterized clinically by an abnormal coat color and development of progressive ataxia during infancy.',0 'The determined value for (k3/k3)app = 120,000 implies that in this case of low specific acyl moiety, penicillin amidase acts more like a transferase than a hydrolase.',0 'Diagnosis of autoerythrocyte sensitization syndrome in the emergency department.',0 'A joint project between the National Bureau of Standards (NBS) and Biomedical Products Department, E.I. du Pont de Nemours and Company, Inc. compared the indicated activity of (a) cobalt-57 samples in NBS 5-ml ampoules, plastic syringes, Du Pont 27-ml Vial E epoxy- and solution-filled containers, and (b) technetium-99m solutions in NBS 5-ml ampoules, elution vials, and syringes.',0 'Empirical support for psychological profiles observed in multiple sclerosis.',0 'Because of its proximity to the target organ, the CSF has long been thought to harbor T cells involved in the pathogenic process.',0 'We demonstrated a slight pyrogenic effect of LPS by measuring oxygen consumption and changes in some parameters of the hematopoiesis.',0 'The major cooperative transition at the highest melting temperatures in the melting profiles of the mononucleosome, dinucleosome and trinucleosome comes from the melting of the central region of DNA in the nucleosome which complexed with the core histones; the premelt region is attributed to two DNA segments per nucleosome which flank this central DNA region and are free or weakly complexed with histones.',0 'We conclude that the majority of benign breast lesions yield characteristic cytologic findings that allow their subclassification when sufficiently sampled by fine needle aspiration.',0 'Thyroid function in chronic excess iodide ingestion: comparison of thyroidal absolute iodine uptake and degradation of thyroxine in euthyroid Japanese subjects.',0 'It has been suggested that sleep apnea may be one mechanism contributing to sleep-related mortality.',0 'This "deficiency" was no longer present at the later fetal period.',0 'The analysis characterizes in detail the migratory behavior of the individual migrating cell with respect to the overall radial glial fiber system as this system varies systematically in its structure with ascent through the strata of the cerebral wall.',0 'Cerebrospinal fluid somatostatin and neuropeptide Y. Concentrations in aging and in dementia of the Alzheimer type with and without extrapyramidal signs.',0 'In cured patients taking 750 mg mefloquine, peak plasma drug concentration (Cmax) and area under the plasma concentration-time curve (AUC) were significantly greater than in the patients for whom treatment failed (p less than 0.0005 and p less than 0.01, respectively), and plasma mefloquine levels were significantly higher from 8 hours to 18 days after treatment.',0 'The medical directorship.',0 'Prevalence and significance of muscle tenderness during common migraine attacks.',0 'In the normal rat only a few L-ENK-I neurons appear dispersed in the stratum griseum superficiale.',0 'Smoking may contribute to the increased CEA levels seen in patients with alcoholic liver disease and pancreatitis.',0 'Exercise hypertension is the blood pressure response to dynamic exercise stress which is considered excessive as compared to what is normally observed in a healthy population.',0 'In this work we review prognosis, follow-up and therapy of 46 multicentric disease reported in the literature.',0 'NAAG levels determined by this liquid phase RIA and by HPLC were essentially identical after correction for the presence of NAA crossreactivity.',0 'CEO Summit. Building the new health care delivery alliance, Part II. Roundtable discussion.',0 'Putative transformation-dependent proteins in the blood plasma of tumor-bearing rats and cancer patients.',0 'Transmissible mink encephalopathy (TME) is a rare foodborne disease of ranch-raised mink produced by an as yet unidentified contaminated feed ingredient.',0 'The end result was a mean reduction of $535 in the cost of periodontal treatment that had been planned before using the counter-rotational brush over 18 months, while the group using the manual brush experienced a mean increase of $11 in required treatment over original plans.',0 'Technology assessment in critical care.',0 'The relationship of atypical lymphocytes, phenothiazines, and schizophrenia.',0 'Statistical analyses compared a moderator model to a mediational model and a cumulative risk model.',0 'Histochemical studies in stomatal apparatus of Phaseolus mungo Linn. 3. Localization of ascorbic acid and peroxidase and their functional significance.',0 'On the eighth day post infection all surviving E. tenella infected chicks and two replicates per dietary treatment of control and E. acervulina infected chicks were killed.',0 'Plague (infection by Yersinia pestis) was present in Hawaii for the period 1899-1957 and caused at least 370 fatalities.',0 'Many of these organisms appear to be degenerating.',0 'Joint ventures in health care.',0 'The extent of the binocular cortical field in albino mice, as revealed by recording from single cells, was almost normal; although the input from the ipsilateral eye was weaker than normal, most cells were driven from both eyes.',0 'Comparative peptide sequences of kappa and lambda chains of human immunoglobins.',0 'Many of the new findings are related to electron microscopy, quantitative lipid composition studies, and the hormonal and nonhormonal control of sebaceous gland secretion.',0 'Although Lyme disease (LD) is the most common tick-borne disease in the United States, little is known about the frequency of and risk factors for infection with Borrelia burgdorferi in occupational groups.',0 'Reversal of daunomycin and vinblastine resistance in multidrug-resistant P388 leukemia in vitro through enhanced cytotoxicity by triterpenoids.',0 'Doppler velocimetry of umbilical artery applied in management of high risk pregnancies improves the perinatal outcome and can thus be considered a clinical method of fetal surveillance.',0 'The distal TCPO2 at 2.5 ATA pure oxygen is a reliable test to predict final outcome (healing or no change), when these values were not different in normal air and in normobaric oxygen: (table; see text) In hyperbaric oxygen therapy, when the distal TCPO2 value was inferior to 100 mmHg, all patients showed either no improvement or aggravation, and when the value was higher than 100 mmHg, wound healing was achieved with all patients.',0 '[Obesity. Social-medical and preventive aspects].',0 'The structure studied was a mutant variant of subtilisin, Met222----Gln, and was used because large, uninhibited crystals could be grown, which was not the case for the native molecule.',0 'Concentration-response curves of the a/b ratio of the finger plethysmogram showed that the plasma concentrations required to produce a definite effect are much higher for molsidomine than for SIN-1.',0 'Polyethylene glycol-induced (PEG) fusion was used and hybrids were selected in hypoxanthine-aminopterin-thymidine (HAT) medium.',0 'Though the relationship between serum creatinine and aluminum staining of trabecular bone is unclear, serum creatinine is probably a marker for adequacy of dialysis in these patients.',0 'Information on mortality rates is available for all member countries and the incident number of cancers was estimated for each site, for each country and for the EC as a whole.',0 'During this time the patient showed a progressive loss of cardiac murmurs and over the last 12 months of life developed a dilatated cardiomyopathy associated with congestive heart failure, supraventricular and ventricular tachyarrhythmias.',0 'After characterisation by restriction mapping and Southern hybridisation, the cloned gene was used as a probe to measure URA4 transcription and to examine its regulation.',0 '[Dental criminology].',0 'Preliminary urinary cotinine data also are presented to validate the programs underlying assumption that computer-directed nicotine fading results in across-treatment reductions in biological levels of nicotine.',0 'Twelve male subjects with blood pressure values in the borderline range and 12 normotensive controls were recruited from a blood donation program.',0 'We find that although NA raises cyclic AMP levels through a beta-adrenergic effect, it does not maintain high rates of protein synthesis or high MI in cultured blastemata.',0 'Centromere detection in vinblastine- and radiation-induced micronuclei of cytokinesis-blocked mouse cells by using in situ hybridization with a mouse gamma (major) satellite DNA probe.',0 'By developing alternatives to hospital inpatient care and nursing home care and by investing in primary, secondary, and tertiary prevention efforts, the baby boom population may remain healthier longer and, therefore, may require less medical care than elders today.',0 'In serum and in tissues ST was found to be composed of multiple forms.',0 'Reperfusion is associated with an even larger striatal dopamine release.',0 'With some substrates, the Michaelis constant of the EsD 2 form differed from that of the EsD 1 form.',0 'As compared with ribosomes having the wild-type pseudoknot, the translational activity of ribosomes containing an A, G or U residue at position 18 was dramatically reduced, while the activity of mutant ribosomes having complementary bases at positions 18 and 917 was at the wild-type level.',0 'Differential control of Ca2+-dependent [3H]noradrenaline release from rat brain slices through presynaptic opiate receptors and alpha-adrenoceptors.',0 'These different expression patterns provide evidence for the differential regulation of the two alpha 2-adrenergic receptor genes and warrant further investigation with techniques capable of improved anatomical resolution.',0 'Seventy-two hours after the challenge, mononuclear cells that were producing large amounts of specific IgG antibody appeared in the circulation.',0 'Cyclosporin versus cyclophosphamide for patients with steroid-dependent and frequently relapsing idiopathic nephrotic syndrome: a multicentre randomized controlled trial.',0 'Both supra- and subinhibitory concentrations of cephalexin resulted in filament formation after 4 h of incubation, whereas 24 h of incubation yielded intact filaments at only a narrow range of subinhibitory concentrations of cephalexin.',0 'Absorption and intestinal catabolism of fatty acids in the rat: effect of chain length and unsaturation.',0 '11 of these patients are alive at least 6 months after grafting, 5 of them after more than 2 years.',0 'Asymptomatic destruction of the fornix in man.',0 'Cancer among medical diagnostic x-ray workers in China.',0 'One dealing with abortion, the other with withdrawal of artificial nutrition and hydration.',0 'One complementation group (unc-100) could not be mapped because of the special characteristics of its cohort mutants.',0 'Outcome following occlusion of the middle cerebral artery.',0 'Adenomyoepithelial adenosis and low-grade malignant adenomyoepithelioma of the breast.',0 'The reason for this is uncertain, but further analysis in terms of other parameters such as total tumor number may shed more light on this discrepancy.',0 'A similar pattern of specificity was demonstrated in studies of the binding of 125I-labeled heat-aggregated bovine IgG to various human leukocyte populations.',0 'Gentamicin-resistant Staphylococcus aureus after topical therapy in general practice.',0 'Heparin or ATP[S] inhibited, or delayed the onset of, both vasopressin-induced release of Ca2+ from intracellular stores and vasopressin-stimulated Ca2+ inflow.',0 'The dissociation constants for the competition of isoproterenol for DHA binding sites in normal and asthmatic subjects were virtually identical ( approximately 1.0 muM).',0 'Thirty-five CT scans were studied from patients with several forms of spinocerebellar degeneration.',0 'The results of the immediate consumption demonstrated that the two dietary treatments were significantly and the effect was a lower consumption of food and energy, while the starch an dietary lower consumption of food and energy, while the starch an dietary fiber levels increased.',0 'The sensitizing agent present in active fractions is a high-molecular-weight (m.w. 100,000) protein containing substance.',0 '[Smoking withdrawal treatment with Cytisin (Tabex). Results of a semi-annual survey of former smokers after 4 weeks of therapy].',0 'Of the 38 patients with atrial arrhythmia during LTER 17 had such arrhythmias in their standard ECGs.',0 'He was active in the scientific-literary field to a great age and worked as editor of the Allgemeine Zeitschrift für Psychiatrie from 1924 to 1934.',0 'A pressor response to intubation was seen in the control and A10 groups.',0 'Without systematic error, correlations for end-diastolic and end-systolic volumes were excellent, at r = 0.986 and 0.969, respectively.',0 'Mutants defective in isomerase and decarboxylase activities of the 4-hydroxyphenylacetic acid meta-cleavage pathway in Pseudomonas putida.',0 'A predominantly left to right shunt across the foramen ovale was detected more often in cases with a substantiated coarctation (58%) than in those with an unproved diagnosis (12%).',0 'Weekly incontinence episodes decreased from 10 to three (p < 0.05).',0 'The highest titers of virus were reached in salivary glands in which replication occurred in serous acinar cells.',0 'Current food intake has been shown to directly affect neurotransmission, with resultant modification of behavior.',0 'Labeled proteins were then analyzed by two-dimensional gel electrophoresis (2DGE) and fluorography.',0 'Northern blot analysis revealed the presence of mRNA encoding CD23, CD25 and CD4 in EoL-3 stimulated by IL-3, GM-CSF and IL-5.',0 'At the end of the treatment periods, body, tumor, fundic, and colon weights were noted and gastrin receptor measured.',0 'This virus, together with another vaccinia recombinant encoding biologically active HIV envelope glycoprotein gp160, allowed us to study CD4/gp160-mediated cell-cell fusion in a wide variety of human and nonhuman cells in the absence of other HIV proteins.',0 'Skin grafting was performed after spontaneous eschar separation in 1 breast and after delayed tangential excision after wound demarcation in the other breast.',0 'Multiple defibrillator discharges in a short period of time represent a serious problem.',0 'The lipid bilayer postulated as the basic structural matrix of biological membranes is widely accepted.',0 'Detoxification from methadone maintenance.',0 'Isolation by distance in Middle Dalmatia-Yugoslavia.',0 '[Hemoglobin-oxygen affinity in acute exacerbation of chronic respiratory failure].',0 'In patients with severe liver disease, mean protein C antigen (25% +/- 17%) was lower than Factor X antigen (51% +/- 29%).',0 'Treatment of tularemia with gentamicin in pediatric patients.',0 'Adenocarcinoma of the salivary gland in a beluga whale (Delphinapterus leucas).',0 'Only TN was expressed in control lungs, where it strongly stained the basement membrane of large bronchi and weakly stained alveolar entrance rings and small veins.',0 '[Hygienic regulation of magnesium oxide aerosols in the atmosphere].',0 'Skin and iris pigmentation has also been shown to modify aspects of the heart rate response to injected atropine, although these observations have been generally overlooked.',0 'Scales measuring self-esteem and conscience have been included in a further study of work-related symptoms in students.',0 'Seventeen of 22 group A meningococcal strains were separated into four serotypes by a microbactericidal assay using group A antisera.',0 'Delayed haemorrhagic disease of the newborn with extradural haematoma.',0 'Hybridoma lines were derived by the fusion of spleen cells from mice immunized with native PT, Formalin-detoxified PT, or isolated PT subunits (S1 to S5) with the myeloma line X63-Ag8.653.',0 'During this period of development contacts between the axons of neuroblasts were encountered more frequently that those between the axons and bodies of nervous cells.',0 'The continuing destruction of insulin-secreting B cells seen at the time of death in the diabetic pancreas is unlikely to be due to a direct cytopathic effect of a coxsackie B virus.',0 'An intact basal lamina was present.',0 'This effect is structure specific and dose dependent, being maximum at 200 micrograms/ml of diacylglycerol (DG).',0 'A new inflow cannula has been manufactured according to an original silicone rubber molding process, permitting a hemocompatible inner surface.',0 'Letters: Requirements for testing of hypotheses about molecular coding of experience: transfer studies.',0 'Only seven strains of E. faecalis were inhibited synergistically by the combination of vancomycin with ampicillin, and even then, the concentrations of vancomycin at which synergism was demonstrated were above levels achievable in serum.',0 'Criteria for placement and replacement of dental restorations.',0 'While comparing the results of skin tests with RAST, both in blood and in the nasal secretion, a positive coincidence was found considering the results of skin tests and RAST in serum in 93.8% cases, and in the nasal secretion in 91% of the cases.',0 'First-third ejection fraction at rest compared with exercise radionuclide angiography in assessing patients with coronary artery disease.',0 'Discussion of paper by Frances Pascher, M.D.: systemic reactions to tropically applied drugs.',0 'Furthermore formation of inter-molecular cross-links of collagen from shoulder joint capsule was relatively lower than that of collagens from other major joints.',0 'Methods in heparin depolymerization: oligo-heteropolysaccharides as antithrombotic agents. New frontiers in prophylaxis of venous thrombosis.',0 'Children in Grade I malnutrition (n = 274) contributed much more to this decrease than children with Grades II and III (54 and 5, respectively).',0 'The results define a minimal mechanism: M.K + ATP in equilibrium with (M).',0 'Effects of Ca2+ and a phorbol ester on insulin secretion from islets of Langerhans permeabilised by high-voltage discharge.',0 'Electron microscope observations on Ca2+-ATPase microcrystals in detergent-solubilized sarcoplasmic reticulum.',0 'It is concluded that skeletal musculature adapts itself in a functional manner to the extreme tension demands put on them.',0 '[Schistosomiasis of the central nervous system: report of a case].',0 'The mean number of aspirations in the DG was significantly lower than the NDG (2.2 +/- 2.2 versus 3.3 +/- 2.1; p less than or equal to 0.002).',0 'Experiments of in situ hybridization and PCR amplification revealed that both C5a and FMLP promoted eosinophil IL-8 production through transcriptional gene activation.',0 '[Dermatophytic flora of the Algerian region].',0 'Suppression of convulsive behavior on daily trials was modest in the 15 second group, pronounced with the 30 second group, and drastic with the other groups.',0 'Skin diseases in Saigon.',0 'Morphometric analysis of airways showed similar values of the area occupied by smooth muscle but a significantly lower (P < 0.02) area of airway epithelium in capsaicin-treated rats.',0 'The dominant classical approach is rejected in favour of illuminative evaluation and the approach of new paradigm research.',0 'At low ouabain concentrations (1 X 10(-6) and 1 X 10(-5) M) the potentiating effect on vessel tone and the inhibitory effect on 22Na efflux were transient, so that after 10 min no effect of ouabain was seen.',0 'Blood flow and vascular reactivity in collaterally perfused brain tissue. Evidence of an ischemic penumbra in patients with acute stroke.',0 'The population within the Northern Region of England is 3.09 million.',0 'These differential responses are further magnified by NaCl loading.',0 'In "high" risk and "low" risk gymnasts, injury scores could be classified correctly with 70% and 79% accuracy respectively, so that relative risk status could be determined from simple physical tests which may be employed by practitioners in the field.',0 'Growth factors are polypeptides that play a part in the development and maintenance of living tissues.',0 '[Case of acute renal failure following carbon monoxide poisoning].',0 'This manuscript provides a synopsis of previous work in this field and suggests new directions for the field of myocardial phospholipid metabolism.',0 'No interference from glucose, lactate, or amino acids was observed.',0 'Immunoglobulin, complement components and diphtheroid antigenic material were demonstrated in the glomeruli by immunofluorescence microscopy.',0 'A battery of antibodies directed against fragments of different connexins localized beta 1- and beta 2-gap junction antigens (connexins 32 and 26, respectively) at the intercellular borders of the superficial epithelium while alpha 1-gap junction antigen (connexin 43) was localized to the loose connective tissues.',0 'Ticlopidine activity on platelet function in patients with enhanced platelet aggregation. A short-term crossover study.',0 '[Ulcerative disease in childhood].',0 'Along with studies of DNA unwinding, further understanding of helicase mechanisms requires quantitative studies of the equilibria and kinetics of the multiple, linked reactions among protein, DNA, and nucleotide cofactors, including the protein-protein interactions involved in assembly of the oligomeric helicase.',0 'It is generally accepted that patients with chronic myelogenous leukemia in chronic phase under the age of 50 years who have HLA-identical siblings, should be offered bone marrow transplantation within the first year of diagnosis.',0 'Methods of cleaning waste air (scrubbers/biofilters) are available for problematic cases.',0 'Voluntary movements are preceded by a slow electrical potential of the brain (Bereitschafts-potential, BP) or readiness potential.',0 'G. Whyte Watson.',0 'Single-channel recordings from purified acetylcholine receptors reconstituted in bilayers formed at the tip of patch pipets.',0 'The distribution of thymidine-derived radioactivity did not suggest sequential or preferential labeling of these DNA fractions as the incorporation time was varied.',0 'Psychosocial adjustment showed a slight improvement after surgery.',0 '[Locally acting glucocorticoids in chronic intestinal inflammation].',0 '29, 287-293); duplication of a region straddling the junction of intron 13 and exon 14 generates an alternate splice site, causing an in-frame insertion of 18 nucleotides into mRNA.',0 'RESULTS : During tilt testing six patients became syncopal but 25 were symptom free.',0 'Phage clones carrying the niaD gene were isolated from a C. acremonium library constructed in lambda EMBL3 using the A. nidulans niaD gene as a heterologous probe.',0 'Two patients underwent frontalis muscle sling surgery and a third underwent levator palpebrae superioris muscle resection.',0 'The 18 month survival rate of the control group was about 10% higher than that of the combined treatment group.',0 'DaNa prevents the stimulatory effect of the ionophore A23187 at 25 degrees C, but is ineffective in antagonising the action of X537A.',0 'The authors describe the use of transrectal ultrasound guidance to initially pass a needle across an occlusive web at the coloanal anastomosis after proctosigmoidectomy.',0 'IgE binding was quantified by densitometric scanning and percent inhibition was calculated as well as the respective ratios between required extract concentration for 50% inhibition in heterologous compared to homologous inhibition for each component (inhibition ratio).',0 'RESULTS : The age-standardized CHD mortality rates in the six cohorts ranged from 3% to 20%.',0 'More than 60% of the methotrexate-resistant colonies showed a 2-6-fold amplification of the dhfr gene.',0 'Recurrence of renal amyloidosis was not observed in five patients subjected to Trucut graft biopsies 1, 2, 3, 18 and 72 months post-transplantation.',0 'Twenty normal-hearing adults were evaluated in the 8-20 kHz frequency range on both testing systems.',0 'The dose-response kinetics were biphasic and optimal responsiveness was reached in both instances at 1 fmol/1-10 pmol/1 (this biological effect of ACTH has hitherto not been described).',0 'The possible modes of action of aprotinin in reducing bleeding are discussed, with particular reference to the bleeding which follows cardiac surgery.',0 'Spike-triggered averaging of rectified EMG activity was used to test the output effects of 105 motor cortex cells in two rhesus monkeys (Macaca mulatta) trained to perform alternating wrist movements and power grip.',0 'Immunohistochemically, the epidermal infiltrate was composed of approximately 80% immature T cells (OKT 16) and 30% proliferating cells (Ki 67).',0 'There was no VIP secretion after meal ingestion and addition of bran caused no change.',0 '[The influence of intraperitoneally-applied cortisone derivatives on fresh intestinal sutures and adhesion formation].',0 'The component of gaze selection/control in the development of visual acuity in children.',0 '[Factors determining the level of virus production. 2. The effect of conditions of cultivation on the production of several RNA-containing viruses].',0 'Corresponding cytology was negative in 113/127 (89%) of DNA diploid, 3/36 (8%) of DNA aneuploid and 29/42 (69%) of DNA tetraploid cases.',0 'Maternal transport of immunoglobulins to the calf.',0 'On the day of admission (stage I), 2,3-DPG and P50 in both groups were slightly higher than in the control group.',0 'We have found differences in the response of both hypothalamic nuclei to neonatal castration and differences in the response of the topographic subdivisions of both of them.',0 'The method is an adaptation of the widely used diphenylamine (DPA) reaction to examine DNA in cells grown in a 96-well plate.',0 'There was a linear relation, in the 2 groups, between age and deep vein thrombosis rate, from 10 per cent before twenty to 45 per cent after eighty years old.',0 'These pathological accumulations of radionuclides of TcP-complexes which are distant from joint regions, point to proliferative phenomena in the bone in case of psoriasis especially in alterations of the collagenous metabolism.',0 'These clients are better educated and have a more frequent history of marital difficulties than older adults in general.',0 'After an initial inhibitory effect phenoxybenzamine greatly enhances the ability of the red cell to offload oxygen under conditions seen at the tissue level.',0 'A previously unknown enkephalin-immunoreactive nerve fiber system was revealed in the intermediate lobe.',0 'The decays are biphasic (tau 1 = 200 microseconds and tau 2 = 2 ms), formation of both the photopotential and the bathointermediate being faster than 200 ns.',0 '[Coarctation of the abdominal aorta and arterial hypertension].',0 'This study was undertaken to test the hypothesis that BSO, by inhibiting the synthesis of GSH, spares its constituent amino acids, particularly glutamate, and thereby stimulates cell proliferation.',0 'Liver abscesses in 19 patients were primarily diagnosed by real-time ultrasound.',0 'Improper release of patient from hospital.',0 'The computation of genetic risk in the highly endogamous family of an ancient greek god and goddess has been published in this journal as a pleasant puzzle (Ropartz, 1985 and appendix 1).',0 'The aim of the study was to obtain clinical and laboratory data on patients observed in the major cardiological Institutions, both Universities and Hospital Clinical Centers, in the period 1975-85.',0 'The characteristics of the titin filament in the vicinity of the Z-line were investigated using immunoelectron microscopy.',0 'The experiments also indicate that these two important gene products required for myelin synthesis and assembly seem to be co-regulated.',0 'The private medical sub-sector exerts economic, ideological and political influences on the public health service.',0 'A reflectance instrument was used to measure the variation in UVR-induced erythema at different positions on the back.',0 'Review of the literature indicates that there may be an increased incidence of AML following successful induction of complete remission in patients with SCCL.',0 'In addition, five new missense point mutations were identified: "G6PD Cleveland"820A creates a deduced AA 274 Glu-->Lys; "G6PD West Virginia"910T AA 303 Val-->Phe; "G6PD Fushan"1004A, AA 335 Ala-->Asp; "G6PD Olomouc"1141C AA 381 Leu-->Phe; and "G6PD Praha"1166G AA 389 Glu-->Gly.',0 'Patients with jaw abnormalities required repositioning more often (P < 0.05).',0 'The number of light aircraft (less than 5,700) in the developing world is small compared to those in the West, and little information on aviation accidents is readily available from developing countries.',0 'Concerning diagnostic procedures we recommend beginning with cytology of pleural fluid, which can easily be obtained together with an Abrams biopsy.',0 'In the remaining eggs, a weakly birefringent monaster was assembled in the female pronuclear area.',0 'The hypocalcaemic action of ethanol (3 g/kg body weight) was investigated in intact, thyroparathyroidectomized and antrectomized rats.',0 'Models were fit for all workers, all males, all workers less than 65 years of age, and for all males less than 65 years of age.',0 'The partially purified activity is inhibited by Ca2+ (IC50 approximately 0.4 mM).',0 'The results provide further support for the regulatory role of monoaminergic systems in cognition.',0 'Incidence of the loss of heterozygosity on chromosome 3p was evaluated using 7 polymorphic probes in 35 Japanese patients with sporadic renal cell carcinoma (RCC).',0 'Significant DNA polymorphisms have been reported in the beta-globin gene cluster of epsilon-G gamma-A gamma-psi beta-delta-beta-gene region, in normal (Hb AA) individuals and in patients with sickle cell anaemia (SCA).',0 'The diagnostic AMA scanning showed no side-effects.',0 'The diagnosis of H. capsulatum was suggested by a diagnostic rise in complement fixation titers and positive echocardiographic findings.',0 'The possibility of an association between the anti-neoplastic chemotherapy and the lymphatic leucaemia is discussed.',0 'Differentiation is complete at late confluency.',0 'We conclude that it is important to have local preventive policies in schools.',0 'Plasma, urine, and feces were collected and assayed for total radioactivity; plasma and urine samples were also analyzed for intact didanosine using validated HPLC/UV assays.',0 'Statistical guidelines for The British Journal of Surgery.',0 'A relatively frequent two-allele COMT gene RFLP (PIC = 0.37) was recognized in DNAs digested with BglI.',0 'A 64-year-old man with a two-month history of left shoulder pain and left arm numbness at the medial aspect of the hand and forearm presented for electrodiagnostic examination, and a severe C8 radiculopathy was documented.',0 '[Criteria of clinical diagnosis of multiple sclerosis].',0 'The dichromate reactions for total catecholamines were positive from the 5th day of age when the fluorometric determination was 250 ng of catecholamines (CA) per gland.',0 'Infants viewing texture stimuli had main sequences with slopes comparable to those of adults.',0 'However, enantioselectivity varied qualitatively and quantitatively with substrate as well as with species.',0 '[Therapy of Whipples disease].',0 'We describe in this paper experiments in which oligodendrocytes (from newborn mouse, human embryonic brain, or isolated from adult rat brain) have been transplanted into the brain of the newborn mouse.',0 'ERP findings for children of the alcoholic probands are also discussed.',0 'The kidney vascular system exhibits a resonant frequency at the second harmonic of the heartbeat.',0 'The precedence effect, as investigated by Wallach et al. [Am.',0 'Medium-chain-length dicarboxylic acids have a single low-affinity site.',0 'Comparison of the invasion strategies used by Salmonella cholerae-suis, Shigella flexneri and Yersinia enterocolitica to enter cultured animal cells: endosome acidification is not required for bacterial invasion or intracellular replication.',0 'The overall clinical efficacy was rated "excellent" in 4 (8.9%), "moderate" in 22 (47.8%), and "poor" in 20 (43.5%) cases with a total efficacy rate of 56.5% (26/46).',0 'Group 3 rats demonstrated a short period of normocalcemia after receiving fetal parathyroid allografts.',0 'The pure-tone audiometric configuration and amount of functional loss at least in bilateral cases is thus consistently accounted for on the basis of known and explainable auditory factors.',0 'These results suggest that a critical amount of ischemia is necessary to initiate these changes and may help to explain the fact that not all infants exposed to hypoxia or cold stress developthe disease.',0 'Follow-up at 2 years showed no recurrence, normal sphincter tone, and a normal computed tomography scan.',0 'Traumatic tears of the triangular fibrocartilage are characterised by a linear high signal intensity image (on T1 and T2 weighted sequences), usually situated in the periphery of the articular disk.',0 'Tay-sachs disease. Demonstration of the stored ganglioside in cultured cells from brain biopsy.',0 'In a previous study, patients with spinal cord injuries were observed to have a high incidence of colonizaion of the perineum, rectum, and urethra with Pseudomonas.',0 'Hormonal effects on isolated perfused cat kidneys.',0 'Embryonic synthesis of myoglobin in vivo estimated by radioimmunoassay.',0 '[Association of autoimmune thrombopenia with cancer of the pancreas. A case report].',0 'An attempt was made to interpret the clinical significance of secondary infections associated with lung cancer.',0 'Our results show that myelodysplastic and aplastic cells display a tendency for reduced susceptibility to GM-CSF as compared to healthy controls, while in leukemic bone marrow the response to the growth factor was significantly enhanced, indicating a leukemia-specific response pattern.',0 'The agents used were the novel Ca2+-mobilizing agent, thapsigargin (Tg), the chemotactic peptide, formyl-methionyl-leucyl-phenylalanine (FMLP), and the divalent cation ionophore, A23187.',0 'At stage 28, frontonasal mass cultures form cartilage nodules and the number of nodules in mandible cultures is markedly decreased.',0 'Ninety-five percent of the plateau deposition of body protein was achieved at a dietary methionine concentration of 8 g/kg dry matter or 0.40 g/MJ digestible energy.',0 'In contrast, alpha secreted from cells labeled with [3H]GlcN and [3H]Fuc in the absence of glucose ("glucose-starved") was heterogeneous.',0 'Agreement was highest for traits related to Extraversion and lowest for traits related to Agreeableness.',0 'A prospective randomized trial of external fixation and plaster cast immobilization in the treatment of distal radius fractures.',0 'This provides evidence for a hypothesis about a stimulatory effect of polluted air on immunological mechanisms in child population.',0 'We report 2 cases in which defects in the instruments led to failure of the endoscopic technique, and the stones and broken parts of the ultrasound probe were removed by an open operation.',0 'No difference was noted between the groups in the time taken to regain spontaneous ventilation and to extubation of the trachea, although the alfentanil group tended to be sedated more deeply during the infusion.',0 'Three patients were ex-drug addicts and 6 had received blood transfusions whereas the cause of the infection in the remaining 21 patients was unknown.',0 'With increasing use of maxillary surgery to reduce vertical dimension, it would be appropriate to evaluate methods of predicting autorotation of the mandible.',0 'Interviews regarding AIDS knowledge and related behavior change were conducted with a random sample of 409 unmarried individuals 18-39 years of age in Richmond, Virginia, between March 18 and April 3, 1987.',0 'Multiple bilateral coronary arterial to pulmonary artery fistulae in an asymptomatic patient.',0 'Employee benefits and your bottom line.',0 'Due to combined irradiation, complete remission of the tumour was achieved.',0 '[A retrospective multicenter study of severe aneurysms].',0 'CSF treatment by daily dosing either at 0.4, 2.0, 5.0 and 10.0 micrograms/kg intravenously or at 2.0 and 5.0 micrograms/kg subcutaneously.',0 'Eighty-three percent of all respondents reported that their institution had a formal policy governing the handling of antineoplastic agents.',0 'The administration of cycloheximide with ACTH resulted in a 73% decrease in reductase activity compared to control values, but did not prevent the enhancing effect of ACTH on the reductase mRNA level.',0 '[Sulfonylurea compounds].',0 'Naloxone has been reported to have potential benefit in the treatment of stroke.',0 'Prostate cancer continues to be a leading cause of cancer death in American men.',0 'Focal acinar hyperplasia, acinar adenoma, and acinar carcinoma (found rarely) represent a continuous spectrum of proliferative lesions of the exocrine pancreas.',0 'Reply to Comments on Rn risk estimates in NCRP Report No. 77.',0 'The frequency of suicide in individual Danish birth cohorts, 1922-1991.',0 'However, these findings suggest that A. naeslundii is an occasional saprophyte of the lower genital tract as well.',0 'Both 8 kdalton and 5 kdalton somatostatin 28(1-12)-like peptides contain somatostatin 28(1-12) at their C-termini.',0 'During the first 14 days after randomisation, the early treatment group had five times more taps, and 12 times more cerebrospinal fluid removed.',0 '[Methodological survey of whole blood filtration in the evaluation of erythrocyte deformability. I. Effect of temperature].',0 'Seventy patients more than 16 years of age with untreated idiopathic scoliosis were followed-up for a mean period of 8.5 years.',0 'Maximum stability of metronidazole was at pH 5.6 under zero total buffer species conditions.',0 '[Long-term blood pressure determination in general practice. I: Introduction and general principles].',0 'Authentic dolichyl phosphate [3H]mannose and partially purified mannolipid formed from GDP-[14C]mannose and exogenous dolichyl phosphate were found to function as direct mannosyl donors for the synthesis of labelled mannoproteins.',0 'The use of Vt and Pm appeared to be necessary when a minicomputer was connected to a pressure-compensated flow plethysmograph to obtain an automatic calculation of TGV.',0 'According to the patients subjective evaluation, pain decreased as soon as the first day in both groups, with significant differences in favour of DHEP (p < 0.005).',0 'We report the case of a 59-year-old woman with bronchial asthma treated with steroid therapy for a long time, who developed an invasive pulmonary aspergillosis with an unusual combination of invasive and allergic disease.',0 'When pO2 was low, the organism grew slowly and produced smooth LPS bearing rhamnan sidechains.',0 'It also blocks pressor effects of norepinephrine and phenylephrine and is thus an alpha-adrenergic antagonist.',0 'b) With the exception of the maxillary and mandibular canines, and the mandibular second premolars, the average age for 3/4 resorption of the primary root corresponded to the period between 1/4 and 1/2 formation of the root of the successional permanent tooth.',0 'The ras-related low-molecular-mass GTPases participate in signal transduction involving a variety of cellular functions, including cell-cycle progression, cellular differentiation, cytoskeletal organization, protein transport and secretion.',0 'DNA probes are now available for Echinococcus spp, which are effective for typing isolates.',0 'Both procedures placed the root between the Alphaherpesvirinae and the other two subfamilies.',0 'Binding of histamine and histamine analogs to lymphocyte subsets analyzed by flow cytometry.',0 'After operation the patients were observed for the development of delayed wound healing or wound infection.',0 'Age difference in perceptual judgment on the Mueller-Lyer illusion.',0 'Hence, the present study examined the effect of ethanol on cell proliferation in the two neocortical proliferative zones, the ventricular zone (VZ) and subventricular zone (SZ).',0 'The vesicles are enriched 7-10 times in apical membrane markers.',0 'Even with our current imperfect understanding of the process, a few of the steps in sperm activation may be defined by biochemical pathways that include specific modulatory control points.',0 'The changes observed were restricted to the cortical region where the drug was applied.',0 'Spinal cord transection was combined with transection of all lumbo-sacral dorsal roots.',0 'In group A, the mean of asthmatic history was 19 years and all cases were associated with respiratory tract infections.',0 'Results indicated that the Seashore test did not discriminate between subgroups of these learning-disabled children.',0 'Cross-mixing experiments (i.e. binding of activated cytosol from mature rats to nuclei of immature and vice versa) gave similar results to the non-mixed groups.',0 'In this report, the authors demonstrate that inhibitors of fibrin monomer polymerization have different effects on the aca and fibrometer assays of fibrinogen.',0 'Biochemical and cytochemical evidence indicates that coated vesicles in chick embryo myotubes contain newly synthesized acetylcholinesterase.',0 'To determine the effect of a prior internal mammary artery graft on coronary artery bypass reoperation, experience with 189 consecutive patients who underwent such surgery was reviewed.',0 'Interactions of ioxynil (3,5-diiodo-4-hydroxybenzonitrile) with a pure culture of Erwinia carotovora grown in a glucose-simple salts medium were studied.',0 'The kinetics of inactivation and reactivation of immobilized luciferase in the presence of dithiothreitol were studied.',0 'Histamine and the skin.',0 'Genetic and maternal influence on the first three lactations of holstein cows.',0 'Based on protein binding analysis, one of these regions (that including -80/-40 bp) is distinct from the consensus CRE while the other (that containing -243/-225 bp) may be related to the consensus CRE.',0 'A total of 109 mammals belonging to 3 wild species: Cervus elaphus, Capreolus capreolus and Sus scrofa were examined post mortem after delivery by hunters to the warehouses of the "Jägerprodukt" company in Sławno and Osowo, and of the "Las" company in Sławsko (Middle Pomerania, Poland).',0 'We isolated the genomic clone of the gene bli-3, whose mRNA we have previously shown to be induced 2 minutes after the beginning of illumination.',0 'The toxicity of cassava has been attributed to its two cyanogenic glycosides, linamarin and lotaustralin.',0 'We investigated the utility of a noninvasive respiratory inductive plethysmograph (RIP) to continuously monitor and record the breathing pattern of 44 patients who had been mechanically ventilated.',0 'The puff duration also had no remarkable influence on the TSNA delivery with the exception of a non-filter cigarette made of dark tobaccos.',0 'Dinucleotide repeat loci contribute highly informative genetic markers to the human chromosome 2 linkage map.',0 'The attenuation of the diurnal fall in cortisol after acute idazoxan may be mediated through increased central availability of norepinephrine, and is similar to responses after high doses of the less selective alpha 2-antagonist yohimbine.',0 'There was also a pronounced inhibition of DNA precursor incorporation when verapamil was used in combination with either agent.',0 'Sixty per cent of the recurrent inputs were borne by non-governmental organizations.',0 '[Studies of simultaneous major resection of the liver and pancreas, with special reference to carbohydrate metabolism].',0 'This study explores the reasons why teenagers coming for professional birth control help for the 1st time choose the particular clinic in which they enrolled and the clinic characteristics which may encourage the young patients to come for contraceptive help early or contribute to a delay in seeking services.',0 'In a canine model of severe propranolol poisoning, the combined effect of glucagon 2.5 micrograms/kg and milrinone 100 micrograms/kg brought about a significant hemodynamic improvement, but it was accompanied by an excessive increase of heart rate.',0 'Synthesis and blood pressure lowering activity of 3-(substituted-amino)-1,2,4-benzothiadiazine 1-oxide derivatives.',0 '3) Of the non-epileptic patients, 45% had autonomic symptoms, such as headache, dizziness, tinnitus, nausea and vomiting, while there was no significant correlation between particular neuropsychiatric diagnosis and the EEG pattern.',0 'Cytokines are proteins produced by one cell that are capable of altering the behavior of another cell.',0 'The cells within the vascular wall act as a unit regulating the contraction of smooth muscle cells.',0 'The complication of metastasis from the primary tumor site to the distant organ is difficult to control.',0 'The procentriole increases in length and diameter during its maturation into a basal body.',0 'Penicillin-binding protein (PBP) 7 of Escherichia coli is a poorly characterized member of the family of enzymes that synthesize and modify the bacterial cell wall.',0 'The channel open probability exhibited a sigmoidal dependence on potential with the largest values (near 0.7) at depolarizing patch potentials.',0 'Multifocal lesions were seen throughout the lungs, nasal turbinates, cerebral cortex, and the optic nerve of each eye.',0 'Doppler echocardiographic abnormalities are commonly found in constrictive pericarditis.',0 'Documentation, however, is at present inadequate to exclude the possibility that such levels of intake may impair driving by youths and young adults and pose risk to the fetus.',0 'Three of these patients had abnormal thrombin generation values, 4 had abnormal serum antithrombin III values, and 1 had an elevated platelet count.',0 'The nuclease of another specificity (DNAse II) is also able to reveal dinucleosome periodicity in chromatin of both erythrocytes and sea urchin sperm.',0 'It also confirmed a new view of this species in exhibiting a clone gathering most human strains, as first inferred from multilocus enzyme analysis (Piffaretti et al., 22).',0 'Nine criteria for inappropriate referrals and eight criteria for appropriate referrals were established.',0 'The same cells were detected in the bone marrow as early as the 4th day after birth.',0 '1977 cases with gastric complains but without localized findings like ulcer or cancer were investigated by gastroscopy with biopsies of corpus and antrum ventriculi.',0 'A digital computer program was used to identify and analyze the spatial characteristics of the QRSsE loop.',0 'Changes in vitreous structure that occur with aging are important in the pathogenesis of vitreous liquefaction (synchisis senilis), vitreous detachment, and retinal disease.',0 'The patient received a total of 250 g fructose intravenously over 30 hours.',0 'A decrease of the enzymatic activity was noted predominantly in proximal tubules under loading the animals by isotonic NaCl solution and after adrenalectomy--mainly in distal tubules.',0 'No valvular or coronary arterial disease was diagnosed in any patient.',0 'The maximal number of [3H]-YOH binding sites in the cortex was close to that labelled by the agonist [3H]-paraaminoclonidine ([3H]-PAC).',0 'Peptides in genetic errors of amino acid transport.',0 'Glycoprotein C-1 pretreated with heparin did not adsorb to cells.',0 'Results of phenobarbital analyses are presented for 14 patients with chronic renal failure, and compared using gas-liquid chromatography (GLC), enzyme immunoassay (EIA), and fluorescence polarization immunoassay (FPIA).',0 '[Thiocyanation experiments with phenol ketones. 20. Organic thiocyanogen compounds].',0 'Low birth weight and preterm delivery in relation to early-gestation vaginal bleeding and elevated maternal serum alpha-fetoprotein.',0 'Interactions of epileptiform EEG discharges and cognition.',0 'The other family (the 60K family) has a major component with molecular weight approximately 60,000 and includes other polypeptides with molecular weights ranging from approximately 14,000 to about 70,000.',0 'Management of the burn unit.',0 'It was found in the sweat glands, both in the lumen and the fundic epithelium, in some skin samples.',0 'The principal indication for IABP support initially was cardiogenic shock, but over the years, preoperative support, weaning from cardiopulmonary bypass and unstable angina have become the primary indications.',0 'CONCLUSIONS : Pentoxifylline improves survival after CLP without inhibiting TNF synthesis or expression of CD11b/CD18 on leukocytes.',0 'This retrospective study documents the diagnostic and therapeutic value of steroid injections in patients with carpal tunnel syndrome.',0 'Details of recent equipment-oriented malpractice suits are reviewed to identify already proven vulnerable areas.',0 '269, 6725-6728), these authors proposed that K+ transport by the PPase is dependent on its association with other membrane components lost during purification.',0 'The present study demonstrates that CRF-ir neuronal groups in rat forebrain are not homogenous in that each population received a characteristic neural input.',0 'A computerized sperm motion analysis [published erraturm appears in Fertil Steril 1986 Nov;46(5):980].',0 'Resultant analysis was used to measure the pKb for pirenzepine antagonism of negative inotropy to carbachol.',0 'The former two modified bases are known DNA adducts formed by the human carcinogen vinyl chloride; beta is formed by pyrimidine ring-opening of epsilon Ade.',0 'Electron microscopy of sectioned, negatively stained, freeze-fractured, and frozen-hydrated Ca2+-ATPase crystals indicates that they consist of stacked lamellar arrays of Ca2+-ATPase molecules.',0 'Using the ultrastructural immunoperoxidase method, dense reaction product was recognized in alveolar lining material as granular deposits, closely associating with tubular myelin figures that were often observed in the basal layer of alveolar lining layer.',0 'After iv bolus injection of N-methyl-[ring-3,5-3H] tyramine ([3H]MT) 14.8 MBq/kg in rabbits, the plasma concentration-time data was found to be in accordance with the 2-compartment model.',0 'Rats from group 1 received allotransplanted adult parathyroid glands and showed no evidence of graft function.',0 'Weightless rats showed greater changes in the fluidelectrolyte metabolism and ion regulatory function of the kidneys than centrifuged rats.',0 'They were strongly cytotoxic for the autologous lymphoma cells, whereas autologous PHA blasts were not killed.',0 'Thus, only those natural or mutant pituitary or placental hormones with high binding affinity to GH receptors induce mammary development, suggesting that GH receptors play a central role in this process.',0 'BACKGROUND : The aim of this study was to define the incidence of cervico-vaginal colonization by group B Streptococcus (SGB) in full term pregnancy as well as vertical and horizontal transmission in newborns attended in two public hospitals in Valencia, Venezuela.',0 'Before performing a full laboratory evaluation for sepsis, house officers recorded their impressions of whether the infants were likely to have sepsis.',0 '[Psychopathology of myocardial infarct patients].',0 'Cretinism is marked by irreversible mental and growth retardation.',0 '[Characteristics of the methodology for performing 5-fraction duodenal intubation].',0 'Changes in social interaction may reflect changes in anxiety.',0 'Mean total scores were 60.7 for the DNR group and 69.6 for the non-DNR group (p = 0.0031).',0 'In 11 of these patients with no evidence of complications, pressure measurements remained below 7 mmHg.',0 '[Prophylactic and therapeutic activity of an interferon inducer in mice infected intracerebrally with rabies street virus].',0 '[Osteosynthesis and arthrodesis of the Lisfrancs joint].',0 'Inferred from data on the tapping test, the frequency of an intrinsic oscillation was 5 Hz in the central nervous system, then the critical frequencies were predicted 5/n = 5, 2.5, . . . Hz.',0 'Slices were preincubated with either oxygen or nitrogen (treatment incubation) and the persistent effects of this treatment on [14C]acetylcholine and 14CO2 production from [U-14C]glucose were assessed in a subsequent incubation under optimal conditions (test incubation).',0 'With this in mind, many of Freuds references are collected from the Brazilian Standard Edition of the Complete Psychological Works of Sigmund Freud.',0 'In contrast, at 50 mol% Chol, mineralization inside all liposomes was negligible.',0 'Changes in spontaneous activity and emotional responses of rats treated with 6-hydroxydopamine at the suckling age.',0 'Alcoholism was underdiagnosed; 24% of the clinicians diagnoses included no alcoholism diagnosis, 39% were alcohol abuse, and only 37% were alcohol dependence.',0 'Rheumatoid arthritis evaluated by locomotion score. A population study.',0 'In the in vitro motility experiments, actin filaments of D24A/D25A or E99A/E100A mutants moved in the presence of 0.7% methylcellulose at the velocities of wild-type actin.',0 'After the administration of antibiotics, acridine orange was significantly more sensitive than Grams stain and blood culture (p < 0.05).',0 'Strains of indigenous Escherichia coli, Bacteroides, and Lactobacillus were isolated from the gastrointestinal tracts of specific pathogen-free (SPF) mice.',0 'Increases in MICs of 4- to 32-fold were observed for ampicillin, carbenicillin, erythromycin, novobiocin, rifampin, chloramphenicol, nalidixic acid, and oxolinic acid.',0 'A study was performed to determine the morbidity and mortality from ischaemic heart disease (IHD) in patients with heterozygous familial hypercholesterolaemia (FH) and severe hypertriglyceridaemia (pretreatment plasma triglyceride greater than 5 mmol/l).',0 'The phase I study was followed by a phase II study of 5-FU/LV/alpha-IF at the established 5-FU dose in 29 previously untreated patients with disseminated colorectal cancer.',0 'According to previous studies, focal capsulostriatal lesions may produce aphasia, hemineglect, gestural apraxia, frontal lobe dysfunction, and memory impairment.',0 '[The importance of growth factors in endocrinology and oncology].',0 'Titanium centerpieces and modified temperature control system for the Spinco analytical ultracentrifuge.',0 'Baseline function recovered over 24 h, as did the response to CSNS and NE.',0 '[Pericatheter urethrography and its use in post interlocking sound urethroplasty].',0 'Auditory screening of kindergarten children using the VASC.',0 'Initially, the programs concentrated on the isolation of genes encoding (deregulated) biosynthetic enzymes and the development of general molecular biology tools such as cloning vectors and DNA transfer methods.',0 'These findings indicate that both self-administration of an opiate that induces psychic as well as physical dependence and of a non-opiate stimulant inducing psychic but not physical dependence, results in a significant decrease of beta E and related peptides in limbic brain regions of the rat.',0 'The pathway for movement of chloride ions across frog skin is not well understood.',0 'Elevated circulating CEA levels occur in patients with benign gastrointestinal and hepatic disorders.',0 'Respiratory problems during sleep in infants and the elderly and possible relation to mattress compression.',0 'Color transition of neutral red ranges from 6.0 to 8.0 pH units.',0 'Twenty-five patients, median age 69 (range 65-77), without any prior systemic anticancer therapy received a continuous infusion of IL2 at a dose of 18 x 10(6) iu m-2 d-1 for 2 periods of 5 days separated by a 6 day break.',0 'There were no anastomotic disruptions.',0 'The three compartment model gave a reduction in the weighted sum of squared residuals and an improvement in the randomness of scatter of the experimental points about the theoretical curve.',0 'Management of the LE patient, including appropriate diagnostic studies and therapy relevant to the dermatologist, is discussed in the review.',0 'Pharmacotherapy for age-related behavioral deficiencies.',0 'The pathogenicity of bovine faecal isolates of Vibrio fetus var intestinalis serotype v in pregnant ewes.',0 'Different antiestrogens (tamoxifen and its derivatives) and another potent antiestrogen, ICI 164,384, significantly decrease the concentration of estradiol after incubation of estrone sulfate with the different hormone-dependent mammary cancer cell lines.',0 'We have found that the extracellular matrix molecule, tenascin, first appears in the scutate scale dermis at 12 days of development when the scale ridge is established.',0 'Compared with a control group, the treated group showed a significantly positive effect of ALG in the form of a faster reversal of rejection episodes (p less than 0.05).',0 '[Quality criteria for care of patient with accidental injuries].',0 'Neutralization of lymphocyte immortalization by different strains of Epstein-Barr virus with a murine monoclonal antibody.',0 'Continuity of care through improved documentation.',0 'No motilin binding sites were found in the mucosa of the gastrointestinal tract and pancreas.',0 'Molecular weights of 143,000 daltons for casein kinases from 3-, 9- and 18-month-old rats and 211,000 daltons for that from 30-month-old rats were obtained.',0 'Its particularities are difficulties for the histological diagnosis with confusion with Hodgkins disease, a temporary decrease of adenopathies after vincristine therapy, an eosinophilic infiltrate of lymph nodes and a long evolution during at least 4 years.',0 'This paper traces the development of knowledge concerning early lesions of atherosclerosis and the relationship to risk factors in children, youth, and young adults.',0 '[Radiotherapy of lymphogranulomatosis--relations between radiomyelitis and oncogenic alteration of the spinal marrow (authors transl)].',0 'It is concluded that heat stress activates the sympathetic nervous system to stimulate beta-receptor-mediated renin secretion by the kidney, this activation is controlled primarily by internal thermoreceptors, and variations in salt intake alters only the magnitude of the increase in PRA during heat stress, not the mechanisms that produce it.',0 'In this comparison, the laboratory provided a "diagnosis" which was 79% correct.',0 'The new laparoscopic procedure was developed and performed at the Dept., of Obstetrics and Gynecology of the University of Passo Fundo, Brazil.',0 'One tip of the catheter was positioned in the internal iliac artery, proximal and close to the superior glutea artery, through the arteria glutea superior or inferior with ligations of both arteria glutea superior and inferior so as to give high concentration of drugs in the lesion.',0 'The diagnostic possibilities of the microscopic examination of bronchial secretion smears, stained by Grams method, from 56 children with chronic bronchitis at different stages of exacerbation have been studied.',0 'Heart rate variability was used to classify the different patterns into two categories: terminal and decelerative.',0 'In searching for a clue to the role of actin filament bundles organized into polygonal arrays, or geodomes, in lens epithelial cells, we examined several physical events occurring in the young rabbit lens which may initiate their formation.',0 'The data indicate a different organization of certain stages of the meiotic and the mitotic chromosome (Bak et al. 1979).',0 'Advanced extra-uterine pregnancy associated with eclampsia. A report of 2 cases.',0 'The speciation of the chemical forms of arsenic in the biological monitoring of exposure to inorganic arsenic.',0 'Loxiglumide did not prevent the erythromycin-induced reduction in gallbladder volume.',0 'In the same muscle fibre where myofibrils became wavy during K contractures, no waviness appeared during repetitive electric stimulation in normal Ringer (50 shocks/sec, 12 degrees C), although s decreased below 1-5 mum.',0 'Both species show a 30-40% shrinkage of neurons in the layers of dorsal lateral geniculate nucleus receiving axons from the enucleated eye.',0 '[Factors determining the occurrence of tetracycline-induced changes in permanent teeth. Statistical evaluation of a group].',0 'The transtemporal approach gives a more accurate anatomical definition of the facial nerve.',0 'Minocycline excretion and distribution in relation to renal function in man.',0 'These two cases have been subjected to microspectrophotometric measurement of cell DNA as an objective test for the evaluation of risk in breast fibrocystic disease.',0 'To recover these proteins in outer membranes, it was necessary to transfer the Y. pestis low-Ca++ response plasmid to Yersinia pseudotuberculosis.',0 'Smooth pursuit showed large errors in most patients and several controls but none of the at-risk subjects.',0 'The maneuver was carried out under US guidance in 7 patients, using stereotaxic equipment in 88 patients and without stereotaxic equipment in 298 patients.',0 'They show that numbers of obstetric and gynecologic operations have decreased over the last five years, in spite of constantly increasing numbers of obstetrician-gynecologists.',0 '[Therapeutic value of functional laterocervical lymph node dissection in cases of capsular rupture].',0 'The Mr 54,000 component was identified as a tubulin subunit by immunoprecipitation with antitubulin monoclonal antibodies.',0 'Current state of cementless hip prostheses.',0 'This was shown using a system where adult F1 hybrid rats between two inbred strains were inoculated with T lymphocytes from one parental strain.',0 'Eight of them belonged to the group of 16 patients with catecholamine bombs and five belonged to the group of 49 patients with no bombs; the difference (8/16 versus 5/49) is very clear (p less than 0.001).',0 'In experimental alcohology, on different animal models (alcohol preferring or alcohol dependent) acamprosate induces a very clear and highly significant reduction of alcohol consumption.',0 '[Morphometric analysis of gastric dysplasia and malignancy].',0 'This Na+ leak likely occurs via incompletely inactivated voltage-gated Na+ channels.',0 'At acid pH values cathepsin B also released hydroxyproline from human glomerular basement membrane but the lysosomal carboxyl proteinase, cathepsin D, had no action.',0 'The ribosomal DNA(rDNA)-containing chromatin in eukaryotes forms a unique architecture called the "secondary constriction" or "nucleolus organiser region (NOR)" on mitotic chromosomes.',0 'Alkylation of cellular components, particularly DNA, is a critical event in the initiation of tumours by these carcinogens.',0 'Changes in late auditory evoked potentials induced by growth hormone-releasing hormone (GHRH) but not somatostatin (SRIF) after peripheral administration in male controls.',0 'e. CPB was observed on mesothelial cells in ascites, explaining the high level of CPB in ascites.',0 'Preoperative irradiation in clearly operable tumours can be given with a short course of 5 x 5 Gy over 5 days as the method of choice.',0 'The univariate regression results suggested a positive relationship between the Brooke and Jebsen scales.',0 'Biochemical and genetic approaches to the study of mammalian mitochondrial tRNAs.',0 'Silicon carbide may be one of the major etiologic agents in this case of pneumoconiosis.',0 'It can be concluded that epitopes specifically recognized by T lymphocytes of patients with myasthenia gravis also represent specific T-cell epitopes in the autoreactivity to the acetylcholine receptor in mice and that immune responsiveness to these peptides is influenced by the genetic make-up of the responding mouse strains.',0 'The utilization of these compounds and the growth correlated with the cleavage of the C-N bond and thereby with the formation of trimethylamin.',0 'Application of epidemiological methodology to sports and exercise science research.',0 'However, the higher protein diet with sodium bicarbonate improved nitrogen utilization.',0 'These changes are pathognomonic of a cystic malformation.',0 'The labeled product was coincident with a band on Coomassie Blue stained gels migrating slightly above an unlabeled thrombin band at Mr approximately 31,000.',0 'On 3rd, 4th, 5th, 6th day of life 4 standard heparinized microtubes were filled after lancing the heel: 2 microtubes to estimate the mean value of total bilirubin, 2 for the mean value of pH.',0 'CONCLUSIONS : We recommend that IOP be measured only after HR and MAP have returned to preintubation levels in children who have undergone tracheal intubation during halothane and N2O anesthesia.',0 'Forearm circulation in man at high altitude.',0 'In addition, the flavonol quercetin was able to compete for [3H]17 beta-oestradiol (E2) binding to type II EBS, the relative binding affinity (RBA) of quercetin being greater than that of diethylstillboestrol (DES).',0 'The key role of T cells in the antiplasmodial immune response is now well established, but all the regulatory heterogenous mechanisms are not yet fully known.',0 'Between 1964 and 1990 we examined 2588 women by galactography and performed 826 duct excisions.',0 'Liposomal-interferon was retained locally from one to three days, depending on liposome composition, whereas an equivalent injection of free interferon was undetectable after 24 hrs.',0 'Animals were immunized with either killed Pseudomonas aeruginosa or pyrogen-free Burns-Tracey saline (BTS) and challenged at various times post-immunization (p.i.) with a lethal dose of viable P. aeruginosa.',0 'Exploration revealed a bony lesion involving parts of 2nd and all of the 3rd coccygeal vertebrae.',0 'Effects of cytoskeletal inhibitors on water proton relaxation time changes in unfertilized and fertilized sea urchin eggs.',0 'Betablockers and calcium antagonists are now the corner store of antihypertensive therapy aimed at protecting the heart.',0 'The ventilation and CO2 chemoreceptor response of a group of infants in natural sleep were compared with those of a group receiving 50 mg/kg of chloral hydrate.',0 'It reveals that whereas uridine monophosphate and glutamate act competitively with respect to L-glutamine, carbamylphosphate and asparagine act non-competitively.',0 'The high DPG concentrations may compensate for the anemia by decreasing the hemoglobin-oxygen affinity and thereby facilitating tissue oxygenation at low hematocrits.',0 'Sinus nodal function was analyzed in 25 dogs by premature stimulation of the right atrium.',0 '[On the biological activity of cyclopentyl ethers of estriol. (Clinico-experimental contribution)].',0 'The interval between arrest and application of the pacemaker was prolonged because of long periods for ambulance response, field resuscitation, and transport.',0 'In order of magnitude associations were found between death and year of treatment (P less than 0.01), the type of anastomosis performed to correct the atresis (P less than 0.05), the presence of other congenital abnormalities (P less than 0.01) and presence of a malrotation (P less than 0.02).',0 'Uracils with the following substituents in position 5 were used: i-propyl, i-butyl, i-pentyl, sec-butyl, n-butyl, phenyl, benzyl, phenylethyl, methylthioethyl, ethylthiomethyl, and ethylthioethyl.',0 'The system allows simple, automated, and economical production of purified proteins with higher quality than that possible with current production methods.',0 'INTERVENTIONS : Fifty-five patients received combination therapy with zidovudine and didanosine, and 14 received zidovudine therapy alone (600 mg/d).',0 'The fibroblasts could be maintained in culture using standard methods and morphologically resembled those of synovial rather than dermal origin.',0 'We used a quasi-experimental "before and after" design to assess the impact of two college physics courses, and we examined selection-bias, test-retest, and task-format factors directly.',0 'Transcription of one or the other of these two genes is linked to a genetic rearrangement implying duplication and transposition of the "basic" coding sequence.',0 'The ultrastructural study provided evidence for the production and accumulation of secretory products (mucolipids) by the tumor cells.',0 'We conclude that coronary spasm as well as intracoronary thrombosis plays an important role in the production of acute myocardial infarction.',0 'Is radiology a nine to five specialty?',0 'Although the biological action of phthalates has been widely discussed there is little information on early cellular changes indicative for toxic or carcinogenic effects.',0 'Platelet function in congenital afibrinogenemia.',0 'The current activation displayed an instantaneous component followed by a monoexponential increase (tau a) to a peak amplitude.',0 'Against this background of tasks yet to be undertaken, we can be optimistic that we are on the brink of understanding the triggers that alter pain sensitivity, that we shall soon know which mediators are involved, and that this will give rise to new strategies for the prevention as well as the alleviation of pain.',0 'The excimer laser was operated at 308 nm, 135 nsec, 25 Hz, and 40 to 60 mjoules/mm2 and was coupled into multifiber wire-guided catheters of 1.4 to 2.0 mm diameter for coronary lesions and into catheters of 2.2 mm diameter for peripheral lesions.',0 'The experimental data and computer simulations of the granulocyte data suggest that time-dependent changes of both passive Ca2+ flux into the cytosol and Ca2+ flux of the plasma membrane pump are involved in the transient [Ca2+]i response.',0 'The nitrogen-15 signal for the coordinated cyanide ion is known to be highly variable among other hemoproteins, but the signal covers a range of only 855 to 865 ppm (nitrate ion reference) for vertebrate cytochromes c and 884 to 886 ppm for yeast cytochromes c. The cyanide ligand probe thus reports an amazing conservation of the heme and proximal ligand environment among the cytochromes.',0 'A striking, previously unreported pattern of orcein-positive deposits attributed to excess copper-binding protein was found in liver-biopsy specimens from twelve cases of Indian childhood cirrhosis.',0 'No recurrence of NPT was observed during 3 further courses of aplasia with the use of selective (2 patients) or complete (1 patient) bowel decontamination.',0 'HLA-DR4 is associated with RA.',0 'The best activity was found in the APTT and the thrombin time assays indicating that protease generation and the direct inhibition of thrombin may be sites of actions of this agent.',0 'It has often been suggested that certain personality traits predispose one to develop sympathetically related pain syndromes.',0 'In vivo evaluation was made by hemodynamic studies and the incidence of thromboembolism.',0 'The daily dose of labetalol eventually required to achieve good BP control in this group was relatively low: 600--1200 mg.',0 'This paper presents a procedure which allows for the correlation present, whilst adjusting the multiple p-values.',0 'In radioimmunoassay the relative somatostatin content in the mouse brain was 2-3 times higher than that in the rat.',0 'Fifteen minutes after embolization 10 animals were treated with rt-PA 10 mg kg-1; 11 with 15 mg kg-1; 12 with 20 mg kg-1 and 9 with 10 mg kg-1 + 20 mg kg-1 aspirin and 34 animals with saline.',0 'The information gained in addition to that of these procedures, as well as to that of the four conventional echocardiographic techniques was evaluated.',0 'It exists in the form of beta particles.',0 'Catechol-o-methyltransferase (COMT) activity in erythrocytes of alcoholics did not differ from that of controls.',0 'After maleate treatment the distribution of microvillar and lysosomal markers was unchanged, but the coated pit markers were redistributed--gp330 was concentrated in newly formed apical vacuoles, and clathrin was diffusely distributed in the apical cytoplasm or on apical coated vesicles.',0 'Diastematomyelia and structural spinal deformities.',0 'Vaginal absorption of insulin in the rat: effect of penetration enhancers on insulin uptake and mucosal histology.',0 'The observation is followed by commentaries about the frequency and clinic of Barlow syndrome.',0 '[Neural and cochlear potentials registered through the Eustachian tube].',0 'Learning from experience in the community: an ethnographic study of district nurse students.',0 'A growing understanding of prognostic factors has provided the stimulus for a third option, adjuvant chemotherapy after orchiectomy in high-risk patients.',0 'Resonance energy transfer was measured from extrinsic probes located on each of the cytoplasmic cysteine residues to the retinal in the trapped photoproducts.',0 'In the case of SN-38, the enhanced stability was shown to be due to preferential associations between the drugs lactone form and the blood protein.',0 'The incidence of cleft lip and palate among North American Negroes.',0 'The possible implantation of this animal model in fundamental and practical studies is discussed.',0 'Oral health after periodontal therapy.',0 'Reyes syndrome: a challenge not limited to critical care nurses.',0 'Comparative analysis of the partially purified erythrocyte catalase preparations obtained from normal and heterozygous individuals revealed no distinct differences between them regarding stability to heat, sodium dodecyl sulfate and some enzyme inhibitors or pH dependency.',0 'We conclude that early-stage rat fetal cells might have endogenous factors that promote cell transformation.',0 'Electrophysiologic effects of 50 mg iv ajmaline were evaluated in 10 patients with atrioventricular nodal reentrant paroxysmal supraventricular tachycardia (PSVT) utilizing the slow pathway for antegrade and the fast pathway for retrograde conduction.',0 'The change in affinity for folic acid transport at the two pH conditions may reflect different membrane carriers, or may be due to protonation of a membrane carrier and/or the folic acid molecule, favored at low pH.',0 'Enzyme assays were performed within subcellular preparations and intact cultures by quantifying the total nonpolar 3H-labeled metabolites formed from [3H]E1 sulfate (E1S) and [3H]DHEA sulfate (DHEAS).',0 '[Osteoid osteoma of the spine. Clinical, radiological, isotopic and x-ray computed tomographic study. Apropos of a case simulating spinal cord compression. Review of the literature].',0 'However, when given over prolonged time the adipose compartment plays an important role in the mixture of the product, explaining the prolonged sleep produced.',0 'Evaluation of blood ammonia alterations in uremic patients under hemodialysis and CAPD.',0 'Neocortex, cerebellum and pons (reference region) were delineated using X-ray computerized tomography (CT).',0 'Luminescence analysis of anti-inflammatory agents in blood or plasma following thin-layer chromatographic separation.',0 'Two types of evidence are brought.',0 'During the subsequent 54 days (postshift), all groups performances remained at the approximate level achieved at the end of the preshift period.',0 'In IVF-ET, cleaving embryos were replaced into the uterine cavity about 48 hours after insemination.',0 'The previously suggested correlations between the nonviability of vegetative "petites" mutants, the absence of repression of respiration by glucose, and the incapacity to grow under anaerobic conditions are thus not strictly valid for S. pombe.',0 'Bronchoscopy is a method of choice because broncholiths can be found in a visible zone of the bronchial tree.',0 'No significant responses of plasma oestradiol levels to OGTT were found.',0 'Separation of gametocytes of Leucocytozoon smithi from whole peripheral turkey blood.',0 'The axons arose from either the somata or the dendrites and had a conical initial portion, usually with a smooth contour.',0 '[Lipoma arborescens].',0 '[Pathology of the oral cavity in patients with congenital coagulopathies and HIV infections].',0 'The lengths of the left and right main bronchi were compared and 10 cases (10%) had a ratio less than 1.5 suggesting bronchial isomerism.',0 'The VL sequences of these A48 RI+ mAb has identified amino acid residues lying in four different idiotope-determining regions which may contribute to the structural correlate of this Id.',0 '[Malformations associated with esophageal atresia].',0 'Effect of time errors on infinity values obtained using Pronys method.',0 'Six cases are presented with emphasis on history, diagnosis, and treatment.',0 'The marked inhibition observed in the 10-30 Hz range, even with moderate intensity, suggests that particular attention should be devoted to avoid vibration in that frequency range in vehicles in order to prevent alteration of the performance of sensorimotor systems.',0 'Apoptosis was induced with mitomycin C (MMC), a DNA cross-linking and damaging agent, or with staurosporine (SSP), a protein kinase inhibitor.',0 'AA is inactive per se and its toxic expression is modulated by its alcohol dehydrogenase (ADH) oxidation to form acrolein, which is responsible for the hepatotoxic action.',0 'Occurrence of Australia antigen in chronic hepatitis in Italy.',0 'The technique can be used for the treatment of old cavities as well as for one-stage surgery.',0 'The variability of positions 5 and 11 is moderate, whereas position 8 shows only low substrate specificity in vitro.',0 '[Nursing care and functions in the outpatient clinic].',0 'She has remained free of infection as of the 2-year follow-up.',0 'PATIENTS : A total of 46 mechanically ventilated patients with respiratory failure requiring an inspired oxygen concentration of at least 50% and a PEEP of at least 5 cm of H2O.',0 'After immunization with gp160, specific T-cell proliferative responses were induced in all 40 patients.',0 '[Learning the concept of numbers: a study in thirty children aged 5 to 8 years (authors transl)].',0 'For the classes of 1980, 1981, and 1982, the frequency of medical conditions seen and procedures learned by the medical students have been computed.',0 'The free radicals generated by the azocompounds were carbon radicals and, in the presence of molecular oxygen, peroxyl/alkoxyl radicals.',0 'A monoclonal antibody known to inhibit specifically the ammonia-dependent and glutamine-dependent asparagine synthetase activities but not glutaminase (monoclonal antibody 2B4) binds to both the monomer and the dimer forms of untreated enzyme, as well as to the dimer form of the DON-inactivated enzyme.',0 'The same distribution of H2O2-stimulated cyclooxygenase was obtained when, instead of the MAO-NA system, hydrogen peroxide was generated by GOD in the presence of glucose.',0 'Tumor concentration and distribution of carcinoembryonic antigen measured by in vitro quantitative autoradiography.',0 'This automated injection system is connected to a 25-m methylsilicone fused-silica column which is coupled via an effluent splitter parallel to both detectors and used for screening in routine analysis.',0 'CT also became very useful in these cases.',0 'Each problem was designed to detect a specific heuristic-based bias in making diagnoses.',0 'Second degree block within the bundle branches.',0 'Between January 1986 and August 1988 349 previously untreated patients were recruited who fulfilled the entry criteria: age 15-75 (mean 56 years), stage II-IV.',0 'The facts that IL 2-induced NK boosting could occur without any appreciable production of IFN-gamma in neonatal lymphocytes, and that ample neutralizing doses of anti-IFN-gamma antibody hardly suppressed IL 2-mediated NK boosting even in adult lymphocytes, indicated that the effect of IL 2 on NK boosting might be independent of IFN-gamma production.',0 'DNA histograms revealed diploid distributions in all three samples.',0 'Using the methods of molecular biology, we have been able to clone 5 rat brain specific cDNAs coding for brain specific proteins.',0 'In each, the area of lysis was shown at operation to be related directly to a region in which there was a local defect in the cement mantle surrounding the stem.',0 'We have also selected a variant clone that has lost the capability for cell spreading.',0 'As a simple and direct means for comparison purposes this method was particularly useful for differentiating genetically similar organisms such as Bacteroides strains of the same species which shared greater than 75% homology.',0 'The 12 lesions in this group were evenly divided between MIH (six) and recurrent ASO (six).',0 'The single-chain hybrid was found to bind with high affinity to both truncated soluble insulin receptors and membrane-bound holoreceptors.',0 'These studies demonstrate that the large amounts of lactate appearing in human eccrine sweat can be accounted for by glandular metabolism and that both glycogen and glucose can be used as substrates.',0 'Clinical and experimental aspects of psychedelic drugs.',0 'Chemical modification of mitochondrial transhydrogenase: evidence for two classes of sulfhydryl groups.',0 '[The effect of hormones on renal function through the neurosecretory system of the hypothalamus].',0 'These IPSPs were also partially occluded when they were evoked simultaneously, which implied that some HCN-activated neurons inhibit both i-AB motoneurons and ipsilateral neck motoneurons.',0 'tarsalis should be most susceptible to infection in years with wet winter-early spring periods followed by cool springs.',0 'When both angiotensin and histamine were infused with antibody, the median tumour:liver ratio was 3.09 (i.q.r. 2.22-4.31), significantly greater than for systemic delivery (P = 0.01) but not significantly different from that obtained following the addition of histamine alone (P = 0.94).',0 'In an epidemiological study, nine isolates of dematiaceous fungi were recovered from the interior of a local feed and seed warehouse.',0 'These problems and the approach to asthma concomitant with other diseases are discussed.',0 'The higher-order autoregressive (AR) activity of a physiological system (Sato 1975a,b; Sato et al., 1977) was decomposed into first- and second-order activities.',0 'Visual, somatosensory and acoustic stimulation revealed both diffuse and regionally specific thermoreactions of the brain as well as multiple local termoresponses.',0 'Confirmation of a proteins cysteine content and of its location within the amino acid sequence is crucial in investigating the structural integrity of recombinant proteins.',0 'At one year follow-up examination the result was excellent.',0 'Intrahepatic cholestasis may result from obstruction of intrahepatic bile ducts or alteration of secretory mechanisms by the hepatocyte.',0 'The relevance of these findings to the understanding of the biochemical basis of suramin toxicity is discussed.',0 'Dissociation of proliferative and differentiative signals for human suppressor T cells.',0 'The treatment of strangulating hernias, usually an emergency operation, has not seen any recent technical progress.',0 'Phenotypically, this abnormal B-cell population corresponded to late B or early pre-plasma cells (20% to 80% of PBMC), as defined by the concomitant expression of low densities of CD19 and CD20, moderate densities of CALLA and PCA-1, and strong expression of CD45RO on all B cells, with weakly coexpressed CD45RA on a small proportion.',0 'By contrast, the combination of norethisterone and sulpiride (n = 9) suppressed both ovarian steroids to basal values, the suppression being even greater than with sulpiride alone (n = 5).',0 'These megabodies were membrane-delimited and exhibited dense content by electron microscopy, with myelin figures, highly osmiophilic, thick membranous contours, and lucent areas.',0 'A reduction in microbial growth to numbers less than 10(5) per gram of tissue in the wound, measured by quantitative biopsy, was compared with predicted susceptibility test results.',0 'The index subjects differed from the controls in having a greater difference between verbal and performance I.Q., better complex motor skills, and slower left hand finger tapping speed.',0 'The polymerase chain reaction showed multiple mtDNA deletions even in clinically asymptomatic tissues, the pattern of which differed with the type of tissue.',0 'The most common indication for allogeneic transplantation was chronic myeloid leukemia (n = 59), acute myeloid leukemia (n = 56), acute lymphoblastic leukemia (n = 43), and severe aplastic anaemia (n = 14).',0 'In the same time periods, total tripelennamine (free plus conjugated) amounts were found to be 0.92, 1.20, 0.96, 1.30, and 1.31%, respectively, and total amounts 2-[alpha-hydroxybenzyl(2-dimethylaminoethyl)amino]pyridine(alpha- hydroxytripelennamine) plus an unidentified metabolite were found to be 0.16, 3.35, 3.06, 7.46, and 8.85% of the dose, respectively.',0 'Quantitative studies on the adhesive properties of transformed cells have yielded inconclusive and sometimes contradictory results.',0 'Antibiotic prophylaxis regimens for hepatic resections have not yet been assessed and are the same as for conventional biliary surgery.',0 'The significant reduction in lymph cholesterol and fatty acids due to sesame oil feeding may be an important factor in reducing hypercholesterolemia.',0 'Indices of noradrenergic output in depression.',0 'Hemoglobin contains nearly 73% of the bodys iron.',0 'While in the full-term neonates differentiation between subdural and intracerebellar location is relatively easy, in the premature the cerebellar hematoma frequently has a crescentic shape that resembles a subdural collection.',0 'Their average time on study was 64.1 months.',0 'In this study, ROC analyses of previously published data suggest that (1) the accuracy of the DST might be improved by using a 0.5-mg oral steroid dose; (2) incorporation of dexamethasone serum levels does not improve the performance of the DST; and (3) the serum cortisol level used to define "no suppression" (or DST "positivity") should be varied to take into account diagnostic alternatives, prior probability of affective disorder, and the clinical goal for performing the test (e.g., maximizing utility, increasing information).',0 'We report a case of primary broncho-pulmonary cancer presenting as a round, fine walled cyst.',0 'The results from these and other studies have revealed two important mechanisms that regulate the beginning of animal development.',0 'Home health care is good economics.',0 'In vitro, halothane inhibited glutamate Q3s and R.C.I.s, slightly increased succinate Q3s and R.C.I.s, had no significant effect on glutamate or succinate Q4s, and, moderately lowered glutamate and succinate P/O ratios.',0 'Peak insulin action (determined from the time of the maximal glucose infusion rate) was delayed in the studies done at 276 mg/dl (4.7 +/- 0.2 h) compared to that in studies done at mean glucose concentrations of 130 mg/dl (4.3 +/- 0.2 h; P less than 0.05).',0 'with open angle (usually greater than 90 degrees) between the first and the second part of the P.2) Orthogonal ECG: P +/- in Y lead with a negative mode greater than 40 msec.',0 'Purification of titin and nebulin.',0 'Expression and characterization of human factor IX and factor IX-factor X chimeras in mouse C127 cells.',0